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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1989 1
1991 1
1993 1
1994 1
1995 1
1996 4
1997 3
1998 1
1999 8
2000 12
2001 20
2002 25
2003 21
2004 30
2005 21
2006 27
2007 24
2008 32
2009 29
2010 29
2011 36
2012 35
2013 34
2014 47
2015 44
2016 46
2017 44
2018 52
2019 37
2020 36
2021 54
2022 43
2023 42
2024 23

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182 results

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Filters applied: Review, in the last 5 years. Clear all
Page 1
Pharmacogenomics in Psychiatry Practice: The Value and the Challenges.
Alchakee A, Ahmed M, Eldohaji L, Alhaj H, Saber-Ayad M. Alchakee A, et al. Int J Mol Sci. 2022 Nov 3;23(21):13485. doi: 10.3390/ijms232113485. Int J Mol Sci. 2022. PMID: 36362270 Free PMC article. Review.
We also highlight the gene variants that may potentially increase susceptibility to obesity and metabolic syndrome, as the adverse effects of some psychiatry medications. Collectively, the literature revealed that variation of CYP450 activity is mostly investigated in rela …
We also highlight the gene variants that may potentially increase susceptibility to obesity and metabolic syndrome, as the adverse effects o …
Pharmacogenomics in treatment of depression and psychosis: an update.
Jukic M, Milosavljević F, Molden E, Ingelman-Sundberg M. Jukic M, et al. Trends Pharmacol Sci. 2022 Dec;43(12):1055-1069. doi: 10.1016/j.tips.2022.09.011. Epub 2022 Oct 25. Trends Pharmacol Sci. 2022. PMID: 36307251 Free article. Review.
Genetic factors can, to a certain extent, successfully predict the therapeutic effects, metabolism, and adverse reactions of drugs. This research field, pharmacogenomics, is well developed in oncology and is currently expanding in psychiatry. Here, we summarize the …
Genetic factors can, to a certain extent, successfully predict the therapeutic effects, metabolism, and adverse reactions of drugs. This res …
Pharmacogenomics: A road ahead for precision medicine in psychiatry.
Pardiñas AF, Owen MJ, Walters JTR. Pardiñas AF, et al. Neuron. 2021 Dec 15;109(24):3914-3929. doi: 10.1016/j.neuron.2021.09.011. Epub 2021 Oct 6. Neuron. 2021. PMID: 34619094 Free article. Review.
The pharmacogenomics of treatment response encapsulates both pharmacokinetic ("what the body does to a drug") and pharmacodynamic ("what the drug does to the body") effects. ...Nonetheless, advances in genomics and health informatics present distinct opportunities for psyc …
The pharmacogenomics of treatment response encapsulates both pharmacokinetic ("what the body does to a drug") and pharmacodynamic ("w …
A Review of the Important Role of CYP2D6 in Pharmacogenomics.
Taylor C, Crosby I, Yip V, Maguire P, Pirmohamed M, Turner RM. Taylor C, et al. Genes (Basel). 2020 Oct 30;11(11):1295. doi: 10.3390/genes11111295. Genes (Basel). 2020. PMID: 33143137 Free PMC article. Review.
Cytochrome P450 2D6 (CYP2D6) is a critical pharmacogene involved in the metabolism of ~20% of commonly used drugs across a broad spectrum of medical disciplines including psychiatry, pain management, oncology and cardiology. Nevertheless, CYP2D6 is highly polymorphic with …
Cytochrome P450 2D6 (CYP2D6) is a critical pharmacogene involved in the metabolism of ~20% of commonly used drugs across a broad spectrum of …
Pharmacogenomics in psychiatry - the challenge of cytochrome P450 enzyme phenoconversion and solutions to assist precision dosing.
Mostafa S, Polasek TM, Bousman CA, Müeller DJ, Sheffield LJ, Rembach J, Kirkpatrick CM. Mostafa S, et al. Pharmacogenomics. 2022 Oct;23(15):857-867. doi: 10.2217/pgs-2022-0104. Epub 2022 Sep 28. Pharmacogenomics. 2022. PMID: 36169629 Review.
Pharmacogenomic (PGx) testing of cytochrome P450 (CYP) enzymes may improve the efficacy and/or safety of some medications. ...However, the common occurrence of CYP phenoconversion, a mismatch between genotype-predicted CYP phenotype and the actual CYP phenotype, currently
Pharmacogenomic (PGx) testing of cytochrome P450 (CYP) enzymes may improve the efficacy and/or safety of some medications. ...However
Precision Psychiatry Applications with Pharmacogenomics: Artificial Intelligence and Machine Learning Approaches.
Lin E, Lin CH, Lane HY. Lin E, et al. Int J Mol Sci. 2020 Feb 1;21(3):969. doi: 10.3390/ijms21030969. Int J Mol Sci. 2020. PMID: 32024055 Free PMC article. Review.
A growing body of evidence now suggests that precision psychiatry, an interdisciplinary field of psychiatry, precision medicine, and pharmacogenomics, serves as an indispensable foundation of medical practices by offering the accurate medication with the accu …
A growing body of evidence now suggests that precision psychiatry, an interdisciplinary field of psychiatry, precision medicin …
The emergence, implementation, and future growth of pharmacogenomics in psychiatry: a narrative review.
Bousman CA, Maruf AA, Marques DF, Brown LC, Müller DJ. Bousman CA, et al. Psychol Med. 2023 Dec;53(16):7983-7993. doi: 10.1017/S0033291723002817. Epub 2023 Sep 29. Psychol Med. 2023. PMID: 37772416 Free PMC article. Review.
This is, in part, attributed to interindividual variation in genes that are involved in pharmacokinetic (i.e. absorption, distribution, metabolism, elimination) and pharmacodynamic (e.g. receptors, signaling pathways) processes that in large part, determine whether a medication w …
This is, in part, attributed to interindividual variation in genes that are involved in pharmacokinetic (i.e. absorption, distribution, meta …
The Autism Spectrum: Behavioral, Psychiatric and Genetic Associations.
Genovese A, Butler MG. Genovese A, et al. Genes (Basel). 2023 Mar 9;14(3):677. doi: 10.3390/genes14030677. Genes (Basel). 2023. PMID: 36980949 Free PMC article. Review.
Behavioral and psychiatric conditions in autism impacted by genetics influence clinical evaluations, counseling, diagnoses, therapeutic interventions and treatment approaches. Pharmacogenetics testing is now possible to help guide the selection of psychotropic medications …
Behavioral and psychiatric conditions in autism impacted by genetics influence clinical evaluations, counseling, diagnoses, therapeutic inte …
Pharmacogenomics in pregnancy.
Betcher HK, George AL Jr. Betcher HK, et al. Semin Perinatol. 2020 Apr;44(3):151222. doi: 10.1016/j.semperi.2020.151222. Epub 2020 Jan 25. Semin Perinatol. 2020. PMID: 32081407 Free PMC article. Review.
The efficacy of medications is affected by the many physiological changes during pregnancy, and these events may be further impacted by genetic factors. Research on pharmacogenomic and pharmacokinetic influences on drug disposition during pregnancy has lagged behind other …
The efficacy of medications is affected by the many physiological changes during pregnancy, and these events may be further impacted by gene …
A Narrative Review on Pharmacogenomics in Psychiatry: Scientific Definitions, Principles, and Practical Resources.
Palumbo S, Mariotti V, Pellegrini S. Palumbo S, et al. J Clin Psychopharmacol. 2024 Jan-Feb 01;44(1):49-56. doi: 10.1097/JCP.0000000000001795. Epub 2023 Nov 12. J Clin Psychopharmacol. 2024. PMID: 38100778 Review.
PURPOSE/BACKGROUND: Pharmacogenetics (PGx) studies the genetic factors underlying interindividual variability in drug response. ...This review aims at further highlighting the importance of PGx-driven clinical decision making for psychotropic medications and raising psychi …
PURPOSE/BACKGROUND: Pharmacogenetics (PGx) studies the genetic factors underlying interindividual variability in drug response. ...Th …
182 results