A comparison of 2H2O and phenylalanine flooding dose to investigate muscle protein synthesis with acute exercise in rats.
Am J Physiol Endocrinol Metab. 2009.
PMID: 19366878
Free PMC article.
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Mixed muscle protein synthesis and breakdown after resistance exercise in humans.
Am J Physiol. 1997 Jul;273(1 Pt 1):E99-107. doi: 10.1152/ajpendo.1997.273.1.E99.
Am J Physiol. 1997.
PMID: 9252485
Mixed muscle protein fractional synthesis rate (FSR) and fractional breakdown rate (FBR) were examined after an isolated bout of either concentric or eccentric resistance exercise. Subjects were eight untrained volunteers (4 males, 4 females). Mixed …
Mixed muscle protein fractional synthesis rate (FSR) and fractional breakdown rate (FBR) were examined after an isolate …
Timing and distribution of protein ingestion during prolonged recovery from resistance exercise alters myofibrillar protein synthesis.
J Physiol. 2013 May 1;591(9):2319-31. doi: 10.1113/jphysiol.2012.244897. Epub 2013 Mar 4.
J Physiol. 2013.
PMID: 23459753
Free PMC article.
Clinical Trial.
We determined how different distributions of protein feeding during 12 h recovery after resistance exercise affects anabolic responses in skeletal muscle. ...Muscle biopsies were obtained at rest and after 1, 4, 6, 7 and 12 h post exercise. Rest …
We determined how different distributions of protein feeding during 12 h recovery after resistance exercise affects anabolic r …
Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men.
J Appl Physiol (1985). 2009 Sep;107(3):987-92. doi: 10.1152/japplphysiol.00076.2009. Epub 2009 Jul 9.
J Appl Physiol (1985). 2009.
PMID: 19589961
Free article.
This study was designed to compare the acute response of mixed muscle protein synthesis (MPS) to rapidly (i.e., whey hydrolysate and soy) and slowly (i.e., micellar casein) digested proteins both at rest and after resistance exercise. ...MPS was …
This study was designed to compare the acute response of mixed muscle protein synthesis (MPS) to rapidly (i.e., whey hy …
Myofibrillar muscle protein synthesis rates subsequent to a meal in response to increasing doses of whey protein at rest and after resistance exercise.
Am J Clin Nutr. 2014 Jan;99(1):86-95. doi: 10.3945/ajcn.112.055517. Epub 2013 Nov 20.
Am J Clin Nutr. 2014.
PMID: 24257722
Free article.
Clinical Trial.
BACKGROUND: The intake of whey, compared with casein and soy protein intakes, stimulates a greater acute response of muscle protein synthesis (MPS) to protein ingestion in rested and exercised muscle. ...CONCLUSIONS: A 20-g dose of …
BACKGROUND: The intake of whey, compared with casein and soy protein intakes, stimulates a greater acute response of muscle …
The response of muscle protein synthesis following whole-body resistance exercise is greater following 40 g than 20 g of ingested whey protein.
Physiol Rep. 2016 Aug;4(15):e12893. doi: 10.14814/phy2.12893.
Physiol Rep. 2016.
PMID: 27511985
Free PMC article.
The currently accepted amount of protein required to achieve maximal stimulation of myofibrillar protein synthesis (MPS) following resistance exercise is 20-25 g. ...MPS was measured with the infusion of (13)C6-phenylalanine tracer and collectio …
The currently accepted amount of protein required to achieve maximal stimulation of myofibrillar protein synthesis (MPS …
Pre-sleep Protein Ingestion Increases Mitochondrial Protein Synthesis Rates During Overnight Recovery from Endurance Exercise: A Randomized Controlled Trial.
Sports Med. 2023 Jul;53(7):1445-1455. doi: 10.1007/s40279-023-01822-3. Epub 2023 Mar 1.
Sports Med. 2023.
PMID: 36857005
Free PMC article.
Clinical Trial.
It remains to be assessed whether pre-sleep protein ingestion can also increase mitochondrial protein synthesis rates. Though it has been suggested that casein protein may be preferred as a pre-sleep protein source, no study has compared the imp …
It remains to be assessed whether pre-sleep protein ingestion can also increase mitochondrial protein synthesis rates. …
Consumption of whole eggs promotes greater stimulation of postexercise muscle protein synthesis than consumption of isonitrogenous amounts of egg whites in young men.
Am J Clin Nutr. 2017 Dec;106(6):1401-1412. doi: 10.3945/ajcn.117.159855. Epub 2017 Oct 4.
Am J Clin Nutr. 2017.
PMID: 28978542
Free article.
Clinical Trial.
However, the effect of consuming protein within its natural whole-food matrix on postprandial protein metabolism remains understudied in humans.Objective: We aimed to compare the whole-body and muscle protein metabolic responses after the consum …
However, the effect of consuming protein within its natural whole-food matrix on postprandial protein metabolism remain …
Ingestion of a Whey Plus Collagen Protein Blend Increases Myofibrillar and Muscle Connective Protein Synthesis Rates.
Med Sci Sports Exerc. 2025 Mar 1;57(3):544-554. doi: 10.1249/MSS.0000000000003596. Epub 2024 Nov 6.
Med Sci Sports Exerc. 2025.
PMID: 39501478
Free PMC article.
Clinical Trial.
Post-prandial myofibrillar and muscle connective protein synthesis rates were higher in the exercised compared with the rested leg ( P < 0.001). ...CONCLUSIONS: Ingestion of a whey (25 g) plus collagen (5 g) protein blend increases both myofi
…
Post-prandial myofibrillar and muscle connective protein synthesis rates were higher in the exercised compared w …
Protein ingestion before sleep improves postexercise overnight recovery.
Med Sci Sports Exerc. 2012 Aug;44(8):1560-9. doi: 10.1249/MSS.0b013e31824cc363.
Med Sci Sports Exerc. 2012.
PMID: 22330017
Thereafter, 30 min before sleep (2330 h), subjects ingested a beverage with (PRO) or without (PLA) 40 g of specifically produced intrinsically [1-C]phenylalanine-labeled casein protein. Continuous intravenous infusions with [ring-H5]phenylalanine and [ring-H2 …
Thereafter, 30 min before sleep (2330 h), subjects ingested a beverage with (PRO) or without (PLA) 40 g of specifically produced intrinsical …
The Effects of Ingesting a Single Bolus of Hydrolyzed Collagen versus Free Amino Acids on Muscle Connective Protein Synthesis Rates.
Med Sci Sports Exerc. 2025 Nov 1;57(11):2394-2408. doi: 10.1249/MSS.0000000000003788. Epub 2025 Jun 13.
Med Sci Sports Exerc. 2025.
PMID: 40523226
Free PMC article.
Clinical Trial.
Blood and muscle tissue samples were collected over 6 h to assess myofibrillar and muscle connective protein synthesis rates and associated signaling responses. ...Similarly, both collagen and free amino acid ingestion did not significantly increase …
Blood and muscle tissue samples were collected over 6 h to assess myofibrillar and muscle connective protein synthes …
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