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1947 1
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1959 6
1960 4
1961 7
1962 5
1963 3
1964 9
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1968 8
1969 6
1970 16
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1972 14
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1974 26
1975 23
1976 12
1977 11
1978 10
1979 22
1980 34
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1982 44
1983 33
1984 17
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1986 32
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1988 38
1989 33
1990 40
1991 35
1992 31
1993 27
1994 29
1995 29
1996 32
1997 27
1998 40
1999 45
2000 43
2001 62
2002 47
2003 49
2004 69
2005 62
2006 75
2007 80
2008 59
2009 81
2010 86
2011 112
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2013 125
2014 138
2015 155
2016 175
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2018 147
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3,502 results

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Page 1
Trial of Sodium Phenylbutyrate-Taurursodiol for Amyotrophic Lateral Sclerosis.
Paganoni S, Macklin EA, Hendrix S, Berry JD, Elliott MA, Maiser S, Karam C, Caress JB, Owegi MA, Quick A, Wymer J, Goutman SA, Heitzman D, Heiman-Patterson T, Jackson CE, Quinn C, Rothstein JD, Kasarskis EJ, Katz J, Jenkins L, Ladha S, Miller TM, Scelsa SN, Vu TH, Fournier CN, Glass JD, Johnson KM, Swenson A, Goyal NA, Pattee GL, Andres PL, Babu S, Chase M, Dagostino D, Dickson SP, Ellison N, Hall M, Hendrix K, Kittle G, McGovern M, Ostrow J, Pothier L, Randall R, Shefner JM, Sherman AV, Tustison E, Vigneswaran P, Walker J, Yu H, Chan J, Wittes J, Cohen J, Klee J, Leslie K, Tanzi RE, Gilbert W, Yeramian PD, Schoenfeld D, Cudkowicz ME. Paganoni S, et al. N Engl J Med. 2020 Sep 3;383(10):919-930. doi: 10.1056/NEJMoa1916945. N Engl J Med. 2020. PMID: 32877582 Free PMC article. Clinical Trial.
BACKGROUND: Sodium phenylbutyrate and taurursodiol have been found to reduce neuronal death in experimental models. ...Participants were randomly assigned in a 2:1 ratio to receive sodium phenylbutyrate-taurursodiol (3 g of sodium phenylbutyrate and 1 g of ta …
BACKGROUND: Sodium phenylbutyrate and taurursodiol have been found to reduce neuronal death in experimental models. ...Participants w …
Sodium Phenylbutyrate and Ursodoxicoltaurine: First Approval.
Heo YA. Heo YA. CNS Drugs. 2022 Sep;36(9):1007-1013. doi: 10.1007/s40263-022-00945-x. CNS Drugs. 2022. PMID: 35907175 Review.
An oral, fixed-dose coformulation of sodium phenylbutyrate and ursodoxicoltaurine (ALBRIOZA(); hereafter denoted sodium phenylbutyrate/ursodoxicoltaurine) is being developed by Amylyx Pharmaceuticals for the treatment of neurodegenerative diseases. ...The approval w …
An oral, fixed-dose coformulation of sodium phenylbutyrate and ursodoxicoltaurine (ALBRIOZA(); hereafter denoted sodium phenylbuty …
Sodium Phenylbutyrate and Taurursodiol: A New Therapeutic Option for the Treatment of Amyotrophic Lateral Sclerosis.
Alqallaf A, Cates DW, Render KP, Patel KA. Alqallaf A, et al. Ann Pharmacother. 2024 Feb;58(2):165-173. doi: 10.1177/10600280231172802. Epub 2023 Jun 3. Ann Pharmacother. 2024. PMID: 37269231 Review.
OBJECTIVE: To review the safety and efficacy of sodium phenylbutyrate and taurursodiol (SP + T) in slowing progression of amyotrophic lateral sclerosis (ALS) compared with pre-existing therapies. DATA SOURCES: A PubMed (from January 1, 2009, to April 13, 2023) and Clinical …
OBJECTIVE: To review the safety and efficacy of sodium phenylbutyrate and taurursodiol (SP + T) in slowing progression of amyotrophic …
Sodium Phenylbutyrate and Taurursodiol.
[No authors listed] [No authors listed] Am J Health Syst Pharm. 2023 Mar 7;80(6):316-318. doi: 10.1093/ajhp/zxac363. Am J Health Syst Pharm. 2023. PMID: 36645072 No abstract available.
Sodium Phenylbutyrate and Tauroursodeoxycholic Acid: A Story of Hope Turned to Disappointment in Amyotrophic Lateral Sclerosis Treatment.
Ketabforoush A, Faghihi F, Azedi F, Ariaei A, Habibi MA, Khalili M, Ashtiani BH, Joghataei MT, Arnold WD. Ketabforoush A, et al. Clin Drug Investig. 2024 Jul;44(7):495-512. doi: 10.1007/s40261-024-01371-1. Epub 2024 Jun 23. Clin Drug Investig. 2024. PMID: 38909349 Review.
As at the end of 2023, five treatments - riluzole, edaravone, dextromethorphan hydrobromide + quinidine sulfate (DHQ), tofersen, and sodium phenylbutyrate-tauroursodeoxycholic acid (PB-TUDCA) - were FDA approved for the treatment of patients with ALS. ...
As at the end of 2023, five treatments - riluzole, edaravone, dextromethorphan hydrobromide + quinidine sulfate (DHQ), tofersen, and sodium …
Phenylbutyrate and beta-cell function: contribution of histone deacetylases and ER stress inhibition.
Khan S, Komarya SK, Jena G. Khan S, et al. Epigenomics. 2017 May;9(5):711-720. doi: 10.2217/epi-2016-0160. Epub 2017 May 4. Epigenomics. 2017. PMID: 28470097 Review.
Incidences of diabetes are increasing globally due to involvement of genetic and epigenetic factors. Phenylbutyrate (PBA) is a US FDA approved drug for treatment of urea cycle disorder in children. ...
Incidences of diabetes are increasing globally due to involvement of genetic and epigenetic factors. Phenylbutyrate (PBA) is a US FDA …
Sodium Phenylbutyrate-Taurursodiol for ALS.
Turnbull J. Turnbull J. N Engl J Med. 2020 Dec 3;383(23):2293-2294. doi: 10.1056/NEJMc2030710. N Engl J Med. 2020. PMID: 33264553 No abstract available.
Sodium Phenylbutyrate-Taurursodiol for ALS.
Herz J, Stüve O. Herz J, et al. N Engl J Med. 2020 Dec 3;383(23):2294. doi: 10.1056/NEJMc2030710. N Engl J Med. 2020. PMID: 33264554 No abstract available.
Sodium Phenylbutyrate-Taurursodiol for ALS. Reply.
Paganoni S, Cudkowicz ME. Paganoni S, et al. N Engl J Med. 2020 Dec 3;383(23):2294. doi: 10.1056/NEJMc2030710. N Engl J Med. 2020. PMID: 33264555 No abstract available.
3,502 results

Searches related to "phenylbutyrate"