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152 results

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Page 1
Cancer therapy using natural ligands that target estrogen receptor beta.
Sareddy GR, Vadlamudi RK. Sareddy GR, et al. Chin J Nat Med. 2015 Nov;13(11):801-807. doi: 10.1016/S1875-5364(15)30083-2. Chin J Nat Med. 2015. PMID: 26614454 Free PMC article. Review.
Estrogen receptor beta (ERbeta) is one of the two key receptors (ERalpha, ERbeta) that facilitate biological actions of 17beta-estradiol (E2). ERbeta is widely expressed in many tissues, and its expression is reduced or lost during progression of many tumors. …
Estrogen receptor beta (ERbeta) is one of the two key receptors (ERalpha, ERbeta) that facilitate biological actions of …
Detection of isoflavones and phytoestrogen-rich plant extracts binding to estrogen receptor beta using a yeast-based fluorescent assay.
Bekić S, Petri E, Krstić S, Ćelić A, Jovanović-Šanta S. Bekić S, et al. Anal Biochem. 2024 Jul;690:115529. doi: 10.1016/j.ab.2024.115529. Epub 2024 Apr 4. Anal Biochem. 2024. PMID: 38582243
The aims of the present study were to evaluate the relative binding affinities (RBAs) of plant-derived phytoestrogens for estrogen receptor beta (ERbeta) using fluorescent biosensor in yeast and to apply this assay for the assessment of the pote …
The aims of the present study were to evaluate the relative binding affinities (RBAs) of plant-derived phytoestrogens for e …
Phytoestrogens and the metabolic syndrome.
Jungbauer A, Medjakovic S. Jungbauer A, et al. J Steroid Biochem Mol Biol. 2014 Jan;139:277-89. doi: 10.1016/j.jsbmb.2012.12.009. Epub 2013 Jan 11. J Steroid Biochem Mol Biol. 2014. PMID: 23318879 Review.
Phytoestrogens are a diverse class of non-steroidal compounds that have an affinity for estrogen receptors alpha and beta, for the peroxisome proliferator-activated receptor (PPAR) family and for the aryl hydrocarbon receptor. ...In addition to …
Phytoestrogens are a diverse class of non-steroidal compounds that have an affinity for estrogen receptors alpha and beta …
SAR Study on Estrogen Receptor alpha/beta Activity of (Iso)flavonoids: Importance of Prenylation, C-Ring (Un)Saturation, and Hydroxyl Substituents.
Mbachu OC, Howell C, Simmler C, Malca Garcia GR, Skowron KJ, Dong H, Ellis SG, Hitzman RT, Hajirahimkhan A, Chen SN, Nikolic D, Moore TW, Vollmer G, Pauli GF, Bolton JL, Dietz BM. Mbachu OC, et al. J Agric Food Chem. 2020 Sep 30;68(39):10651-10663. doi: 10.1021/acs.jafc.0c03526. Epub 2020 Sep 18. J Agric Food Chem. 2020. PMID: 32945668 Free PMC article.
Many botanicals used for women's health contain estrogenic (iso)flavonoids. The literature suggests that estrogen receptor beta (ERbeta) activity can counterbalance estrogen receptor alpha (ERalpha)-mediated proliferation, thus providing a bette …
Many botanicals used for women's health contain estrogenic (iso)flavonoids. The literature suggests that estrogen receptor …
Natural Herbal Estrogen-Mimetics (Phytoestrogens) Promote the Differentiation of Fallopian Tube Epithelium into Multi-Ciliated Cells via Estrogen Receptor Beta.
Zhu M, Takeda S, Iwano T. Zhu M, et al. Molecules. 2021 Jan 30;26(3):722. doi: 10.3390/molecules26030722. Molecules. 2021. PMID: 33573260 Free PMC article.
Phytoestrogens are herbal polyphenolic compounds that exert various estrogen-like effects in animals and can be taken in easily from a foodstuff in daily life. The fallopian tube lumen, where transportation of the oocyte occurs, is lined with secretory cells …
Phytoestrogens are herbal polyphenolic compounds that exert various estrogen-like effects in animals and can be taken i …
Oxyresveratrol Is a Phytoestrogen Exerting Anti-inflammatory Effects Through NF-kappaB and Estrogen Receptor Signaling.
Wei J, Chen JR, Pais EMA, Wang TY, Miao L, Li L, Li LY, Qiu F, Hu LM, Gao XM, Fan GW. Wei J, et al. Inflammation. 2017 Aug;40(4):1285-1296. doi: 10.1007/s10753-017-0572-y. Inflammation. 2017. PMID: 28484893
Recent studies suggest an anti-inflammatory activity of oxyresveratrol, a stilbene extracted from Cortex mori root used in traditional Chinese medicine that also presents estrogen-like activity. We herein tested the hypothesis that oxyreservatrol exerts an anti-infl …
Recent studies suggest an anti-inflammatory activity of oxyresveratrol, a stilbene extracted from Cortex mori root used in traditional Chine …
[Research progress in phytoestrogens of traditional Chinese medicine].
Zhao Y, Zheng HX, Xu Y, Lin N. Zhao Y, et al. Zhongguo Zhong Yao Za Zhi. 2017 Sep;42(18):3474-3487. doi: 10.19540/j.cnki.cjcmm.2017.0135. Zhongguo Zhong Yao Za Zhi. 2017. PMID: 29218931 Review. Chinese.
Phytoestrogens are plant-derived compounds, which have a similarity in structure with human endogenous estrogen 17-beta-estradiol. Structural likeness enables phytoestrogens to interact with estrogen receptors, not simply mimicking the ef …
Phytoestrogens are plant-derived compounds, which have a similarity in structure with human endogenous estrogen 17-b …
Phytoestrogens derived from red clover: an alternative to estrogen replacement therapy?
Beck V, Rohr U, Jungbauer A. Beck V, et al. J Steroid Biochem Mol Biol. 2005 Apr;94(5):499-518. doi: 10.1016/j.jsbmb.2004.12.038. Epub 2005 Mar 23. J Steroid Biochem Mol Biol. 2005. PMID: 15876415 Review.
The benefits of plant extracts from soy and red clover as alternatives to conventional hormone replacement therapy (HRT) have been debated in the past. Here, an attempt has been made to summarize the biochemical and pharmacological data in the light of clinical aspe …
The benefits of plant extracts from soy and red clover as alternatives to conventional hormone replacement therapy (HRT) have …
Screening for Phytoestrogens using a Cell-based Estrogen Receptor beta Reporter Assay.
Chester EM, Fender E, Wasserman MD. Chester EM, et al. J Vis Exp. 2020 Jun 7;(160). doi: 10.3791/61005. J Vis Exp. 2020. PMID: 32568227
Here we present the novel use of a cell-based assay to screen plant extracts for the presence of compounds that have estrogenic biological activity. This assay uses mammalian cells engineered to highly express estrogen receptor beta (ERbeta) and …
Here we present the novel use of a cell-based assay to screen plant extracts for the presence of compounds that have estrogeni …
Ameliorative effects of Schizandra chinensis on osteoporosis via activation of estrogen receptor (ER)-alpha/-beta.
Kim MH, Choi YY, Han JM, Lee HS, Hong SB, Lee SG, Yang WM. Kim MH, et al. Food Funct. 2014 Jul 25;5(7):1594-601. doi: 10.1039/c4fo00133h. Food Funct. 2014. PMID: 24881676
Estrogen deficiency in menopausal women is the main cause of osteoporosis. Phytoestrogen could be a suitable candidate for treatment of post-menopausal osteoporosis. ...Serum estradiol concentration was significantly increased in the SC-treated group. The expression …
Estrogen deficiency in menopausal women is the main cause of osteoporosis. Phytoestrogen could be a suitable candidate for tre …
152 results