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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1956 1
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1979 4
1980 9
1981 5
1982 4
1983 11
1984 9
1985 8
1986 14
1987 12
1988 13
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1990 21
1991 22
1992 20
1993 22
1994 15
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1998 22
1999 34
2000 23
2001 18
2002 25
2003 27
2004 44
2005 49
2006 46
2007 51
2008 46
2009 57
2010 68
2011 81
2012 83
2013 106
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2015 134
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3,658 results

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Page 1
Metabolic challenges and interventions in CAR T cell therapy.
Peng JJ, Wang L, Li Z, Ku CL, Ho PC. Peng JJ, et al. Sci Immunol. 2023 Apr 14;8(82):eabq3016. doi: 10.1126/sciimmunol.abq3016. Epub 2023 Apr 14. Sci Immunol. 2023. PMID: 37058548 Review.
Chimeric antigen receptor (CAR) T cells have achieved true clinical success in treating hematological malignancy patients, laying the foundation of CAR T cells as a new pillar of cancer therapy. ...In addition, we discuss the use of novel approaches to target …
Chimeric antigen receptor (CAR) T cells have achieved true clinical success in treating hematological malignancy patients, laying the …
The principles of directed cell migration.
SenGupta S, Parent CA, Bear JE. SenGupta S, et al. Nat Rev Mol Cell Biol. 2021 Aug;22(8):529-547. doi: 10.1038/s41580-021-00366-6. Epub 2021 May 14. Nat Rev Mol Cell Biol. 2021. PMID: 33990789 Free PMC article. Review.
Cells have the ability to respond to various types of environmental cues, and in many cases these cues induce directed cell migration towards or away from these signals. How cells sense these cues and how they transmit that information to the cytoskeletal mac …
Cells have the ability to respond to various types of environmental cues, and in many cases these cues induce directed cell mi …
Advances in cancer immunotherapies.
Dagher OK, Schwab RD, Brookens SK, Posey AD Jr. Dagher OK, et al. Cell. 2023 Apr 13;186(8):1814-1814.e1. doi: 10.1016/j.cell.2023.02.039. Cell. 2023. PMID: 37059073 Free article.
Therapeutic modalities that engage the immune system to recognize and eliminate cancer, known as cancer immunotherapy, has emerged as a distinct pillar of cancer therapy. Among the most promising treatment approaches are therapeutic vaccines, immune checkpoint blockade, bi …
Therapeutic modalities that engage the immune system to recognize and eliminate cancer, known as cancer immunotherapy, has emerged as a dist …
Pillar-Based Mechanical Induction of an Aggressive Tumorigenic Lung Cancer Cell Model.
Lee G, Cho Y, Kim EH, Choi JM, Chae SS, Lee MG, Kim J, Choi WJ, Kwon J, Han EH, Kim SH, Park S, Chung YH, Chi SG, Jung BH, Shin JH, Lee JO. Lee G, et al. ACS Appl Mater Interfaces. 2022 Jan 12;14(1):20-31. doi: 10.1021/acsami.1c12380. Epub 2021 Dec 16. ACS Appl Mater Interfaces. 2022. PMID: 34914354
Moreover, the pillar-induced morphological deformation in nuclei was accompanied by cell-cycle arrest in the S phase, leading to suppressed proliferation. ...Furthermore, this study highlights the potential use of pillar-based mechanical stimuli as an in vitr …
Moreover, the pillar-induced morphological deformation in nuclei was accompanied by cell-cycle arrest in the S phase, leading …
A Pillar/Perfusion Plate Enhances Cell Growth, Reproducibility, Throughput, and User Friendliness in Dynamic 3D Cell Culture.
Lekkala VKR, Kang SY, Liu J, Shrestha S, Acharya P, Joshi P, Zolfaghar M, Lee M, Vanga MG, Jamdagneya P, Pagnis S, Kundi A, Kabbur S, Kim UT, Yang Y, Lee MY. Lekkala VKR, et al. ACS Biomater Sci Eng. 2024 May 13;10(5):3478-3488. doi: 10.1021/acsbiomaterials.4c00179. Epub 2024 May 2. ACS Biomater Sci Eng. 2024. PMID: 38695610 Free PMC article.
Here, we overcome these challenges by developing a pillar/perfusion plate platform and demonstrating high-throughput, dynamic 3D cell culture. ...The pillar/perfusion plate enhanced cell growth by rapid diffusion, reproducibility, assay throughput, and …
Here, we overcome these challenges by developing a pillar/perfusion plate platform and demonstrating high-throughput, dynamic 3D c …
Effective anticancer agents based-on two Pillar[5]arene derivatives for pancreas cancer cell lines: synthesis, apoptotic effect, caspase pathway.
Karaselek MA, Kuccukturk S, Duran T, Kursunlu AN, Ozmen M, Bozdag C, Alkan S, Varman A, Yildirim MA, Kucukkartallar T, Vatansev C. Karaselek MA, et al. Invest New Drugs. 2023 Apr;41(2):202-209. doi: 10.1007/s10637-023-01343-w. Epub 2023 Mar 11. Invest New Drugs. 2023. PMID: 36905565
This study aimed to evaluate the possible anticancer effects of two different pillar[5]arene derivatives (5Q-[P5] and 10Q-P[5]) on two different pancreatic cancer cell lines in vitro. ...This suggested that it may activate different death pathways for BxPC-3 cell …
This study aimed to evaluate the possible anticancer effects of two different pillar[5]arene derivatives (5Q-[P5] and 10Q-P[5]) on tw …
beta-Catenin transcriptional activity is required for establishment of inner pillar cell identity during cochlear development.
Ebeid M, Kishimoto I, Roy P, Zaidi MAA, Cheng AG, Huh SH. Ebeid M, et al. PLoS Genet. 2023 Aug 28;19(8):e1010925. doi: 10.1371/journal.pgen.1010925. eCollection 2023 Aug. PLoS Genet. 2023. PMID: 37639482 Free PMC article.
The mammalian cochlea is composed of sensory hair cells as well as multiple different types of non-sensory supporting cells. Pillar cells are one type of supporting cell that form the tunnel of Corti and include two morphologically and functiona …
The mammalian cochlea is composed of sensory hair cells as well as multiple different types of non-sensory supporting cells. …
Micro-engineered "pillar forests" to study cell migration in complex but controlled 3D environments.
Renkawitz J, Reversat A, Leithner A, Merrin J, Sixt M. Renkawitz J, et al. Methods Cell Biol. 2018;147:79-91. doi: 10.1016/bs.mcb.2018.07.004. Epub 2018 Jul 27. Methods Cell Biol. 2018. PMID: 30165964
Here, we describe simple, robust, and versatile "pillar forests" to investigate cell migration in complex but fully controllable 3D environments. ...Thus, pillar forests combine the advantages of 2D cell migration assays with the precise definition of …
Here, we describe simple, robust, and versatile "pillar forests" to investigate cell migration in complex but fully controllab …
Impacts of potential anticancer agents based on pillar[5]arene for head and neck squamous cell carcinoma cells.
Kuccukturk S, Karaselek MA, Duran T, Kursunlu AN, Ozmen M. Kuccukturk S, et al. J Cancer Res Clin Oncol. 2023 Sep;149(11):8711-8718. doi: 10.1007/s00432-023-04822-y. Epub 2023 May 1. J Cancer Res Clin Oncol. 2023. PMID: 37126106 Free PMC article.
PURPOSE: This study was conducted to investigate impacts of potential anticancer (associated with apoptosis and caspase pathways) of two newly synthesized derivatives of pillar[5]arene, named as d-Q-P5 and p-Q-P5, on Squamous cell carcinomas of the head and neck (HN …
PURPOSE: This study was conducted to investigate impacts of potential anticancer (associated with apoptosis and caspase pathways) of two new …
Host-Guest Chemistry Triggered Differential HeLa Cell Behavior Based on Pillar[5]arene-Modified Graphene Oxide Surfaces.
Mao X, Cheng M, Chen L, Cheng J, Li H. Mao X, et al. ACS Appl Bio Mater. 2021 Sep 20;4(9):6954-6961. doi: 10.1021/acsabm.1c00623. Epub 2021 Sep 1. ACS Appl Bio Mater. 2021. PMID: 35006995
To address this task, we adopt a strategy, based on bridging the host-guest recognition capacities of pillar[5]arene and good attachment for cell adhesion abilities of graphene oxide, to construct a smart pillar[5]arene triazole-linked naphthalene-modified gr …
To address this task, we adopt a strategy, based on bridging the host-guest recognition capacities of pillar[5]arene and good attachm …
3,658 results