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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1957 1
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1959 4
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1965 16
1966 23
1967 12
1968 15
1969 20
1970 25
1971 30
1972 25
1973 26
1974 22
1975 23
1976 18
1977 14
1978 14
1979 22
1980 14
1981 13
1982 18
1983 7
1984 15
1985 10
1986 10
1987 16
1988 6
1989 10
1990 9
1991 6
1992 5
1993 5
1994 8
1995 5
1996 3
1997 9
1998 5
1999 4
2000 19
2001 17
2002 18
2003 24
2004 7
2005 15
2006 25
2007 30
2008 38
2009 37
2010 34
2011 35
2012 45
2013 46
2014 58
2015 51
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2017 44
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2023 56
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1,406 results

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Page 1
Natamycin (pimaricin).
[No authors listed] [No authors listed] Drug Ther Bull. 1970 Jun 19;8(13):52. Drug Ther Bull. 1970. PMID: 5311190 No abstract available.
Pimaricin in aspergillosis.
Henderson AH, Pearson JE. Henderson AH, et al. Lancet. 1968 Jun 22;1(7556):1377. doi: 10.1016/s0140-6736(68)92082-5. Lancet. 1968. PMID: 4172677 No abstract available.
Fungal keratitis: A review of clinical presentations, treatment strategies and outcomes.
Sharma N, Bagga B, Singhal D, Nagpal R, Kate A, Saluja G, Maharana PK. Sharma N, et al. Ocul Surf. 2022 Apr;24:22-30. doi: 10.1016/j.jtos.2021.12.001. Epub 2021 Dec 13. Ocul Surf. 2022. PMID: 34915188 Review.
The advent of rapid diagnostic tools, molecular methods, in vitro anti-fungal drug sensitivity testing, alternatives to natamycin, targeted drug delivery and most importantly the results of large randomized controlled trials have significantly improved our understanding an …
The advent of rapid diagnostic tools, molecular methods, in vitro anti-fungal drug sensitivity testing, alternatives to natamycin, ta …
Biotechnological production and application of the antibiotic pimaricin: biosynthesis and its regulation.
Aparicio JF, Barreales EG, Payero TD, Vicente CM, de Pedro A, Santos-Aberturas J. Aparicio JF, et al. Appl Microbiol Biotechnol. 2016 Jan;100(1):61-78. doi: 10.1007/s00253-015-7077-0. Epub 2015 Oct 29. Appl Microbiol Biotechnol. 2016. PMID: 26512010 Free PMC article. Review.
Pimaricin (natamycin) is a small polyene macrolide antibiotic used worldwide. This efficient antimycotic and antiprotozoal agent, produced by several soil bacterial species of the genus Streptomyces, has found application in human therapy, in the food and beverage i
Pimaricin (natamycin) is a small polyene macrolide antibiotic used worldwide. This efficient antimycotic and antiprotozoal age
Pimaricin, a new fungistatic.
de ROOY A. de ROOY A. Ophthalmologica. 1961 Jun;141:489. doi: 10.1159/000304109. Ophthalmologica. 1961. PMID: 13743198 No abstract available.
Insight into Structural Characteristics of Protein-Substrate Interaction in Pimaricin Thioesterase.
Fan S, Wang R, Li C, Bai L, Zhao YL, Shi T. Fan S, et al. Int J Mol Sci. 2019 Feb 18;20(4):877. doi: 10.3390/ijms20040877. Int J Mol Sci. 2019. PMID: 30781619 Free PMC article.
In our study, molecular dynamics (MD) simulations were conducted on pimaricin TE-polyketide complex and PRS, as well as pre-organization state (POS), a molecular conformation possessing a pivotal intra-molecular hydrogen bond, were detected. ...Our study advanced a compreh …
In our study, molecular dynamics (MD) simulations were conducted on pimaricin TE-polyketide complex and PRS, as well as pre-organizat …
Engineered biosynthesis of pimaricin derivatives with improved antifungal activity and reduced cytotoxicity.
Qi Z, Kang Q, Jiang C, Han M, Bai L. Qi Z, et al. Appl Microbiol Biotechnol. 2015 Aug;99(16):6745-52. doi: 10.1007/s00253-015-6635-9. Epub 2015 May 8. Appl Microbiol Biotechnol. 2015. PMID: 25952111
Pimaricin is an important antifungal antibiotic for antifungal therapy and prevention of mould contamination in the food industry. In this study, three new pimaricin derivatives, 12-decarboxy-12-methyl pimaricin (1), 4,5-desepoxy-12-decarboxy-12-methyl pim
Pimaricin is an important antifungal antibiotic for antifungal therapy and prevention of mould contamination in the food industry. In
Theoretical Studies of Mutual Effects between 6-m-r Hemiketalization and 26-m-r Lactonization in Pimaricin Thioesterase.
Jiang C, Zhou Y, Tao W, Ji S, Mao Y, Shi T, Zheng J, Bai L, Zhao YL. Jiang C, et al. Chem Asian J. 2023 Apr 3;18(7):e202201229. doi: 10.1002/asia.202201229. Epub 2023 Feb 13. Chem Asian J. 2023. PMID: 36755200
Pimaricin is a small polyene macrolide antibiotic and has been broadly used as an antimycotic and antiprotozoal agent in both humans and foods. ...Our results propose that pimTE could be a bi-functional enzyme, which can synergistically catalyze tandem 6-m-r and 26-m-r for
Pimaricin is a small polyene macrolide antibiotic and has been broadly used as an antimycotic and antiprotozoal agent in both humans
Enzymology of the polyenes pimaricin and candicidin biosynthesis.
Martín JF, Aparicio JF. Martín JF, et al. Methods Enzymol. 2009;459:215-42. doi: 10.1016/S0076-6879(09)04610-2. Methods Enzymol. 2009. PMID: 19362642
Pimaricin and candicidin are prototypical representatives of the "small" and the "aromatic" polyene macrolides, respectively. ...Two transcriptional regulators directly modulate transcription of certain genes in the cluster; an extracellular cholesterol oxidase also partic
Pimaricin and candicidin are prototypical representatives of the "small" and the "aromatic" polyene macrolides, respectively. ...Two
Genome-wide analysis of the regulation of pimaricin production in Streptomyces natalensis by reactive oxygen species.
Beites T, Rodríguez-García A, Santos-Beneit F, Moradas-Ferreira P, Aparicio JF, Mendes MV. Beites T, et al. Appl Microbiol Biotechnol. 2014 Mar;98(5):2231-41. doi: 10.1007/s00253-013-5455-z. Epub 2014 Jan 11. Appl Microbiol Biotechnol. 2014. PMID: 24413916
To investigate the molecular mechanisms that interplay between oxygen metabolism and secondary metabolism in Streptomyces natalensis, we compared the transcriptomes of the strains CAM.02 (deltasodF), pimaricin under-producer phenotype, and CAM.04 (deltaahpCD), pimaricin
To investigate the molecular mechanisms that interplay between oxygen metabolism and secondary metabolism in Streptomyces natalensis, we com …
1,406 results