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Tissue plasminogen activator induces microglial inflammation via a noncatalytic molecular mechanism involving activation of mitogen-activated protein kinases and Akt signaling pathways and AnnexinA2 and Galectin-1 receptors.
Pineda D, Ampurdanés C, Medina MG, Serratosa J, Tusell JM, Saura J, Planas AM, Navarro P. Pineda D, et al. Among authors: navarro p. Glia. 2012 Apr;60(4):526-40. doi: 10.1002/glia.22284. Epub 2011 Dec 7. Glia. 2012. PMID: 22162045 Free article.
Key contribution of CPEB4-mediated translational control to cancer progression.
Ortiz-Zapater E, Pineda D, Martínez-Bosch N, Fernández-Miranda G, Iglesias M, Alameda F, Moreno M, Eliscovich C, Eyras E, Real FX, Méndez R, Navarro P. Ortiz-Zapater E, et al. Among authors: pineda d, navarro p. Nat Med. 2011 Dec 4;18(1):83-90. doi: 10.1038/nm.2540. Nat Med. 2011. PMID: 22138752