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Did you mean piperine lipid cholesterol ratio (5 results)?
Effect of multicomponent crystal of piperine-nicotinic acid on antihyperlipidemic activity in rats.
Octavia MD, Hasmiwati H, Revilla G, Zaini E. Octavia MD, et al. Pak J Pharm Sci. 2023 Nov;36(6):1777-1781. Pak J Pharm Sci. 2023. PMID: 38124418
This study aims to examine the effects of multicomponent nicotinic acid-piperine crystals on antihyperlipidemic activity in rats fed a high-fat diet. To increase the effectiveness of piperine, we prepared multicomponent crystals by the solvent-drop grinding m …
This study aims to examine the effects of multicomponent nicotinic acid-piperine crystals on antihyperlipidemic activity in rats …
Antioxidant efficacy of black pepper (Piper nigrum L.) and piperine in rats with high fat diet induced oxidative stress.
Vijayakumar RS, Surya D, Nalini N. Vijayakumar RS, et al. Redox Rep. 2004;9(2):105-10. doi: 10.1179/135100004225004742. Redox Rep. 2004. PMID: 15231065 Free article.
The present study was aimed to explore the effect of black pepper (Piper nigrum L.) on tissue lipid peroxidation, enzymic and non-enzymic antioxidants in rats fed a high-fat diet. Thirty male Wistar rats (95-115 g) were divided into 5 groups. They were fed st …
The present study was aimed to explore the effect of black pepper (Piper nigrum L.) on tissue lipid peroxidation, enzymic and non-enz …
Effects of piperine on the lipid composition and enzymes of the pyruvate-malate cycle in the testis of the rat in vivo.
Malini T, Arunakaran J, Aruldhas MM, Govindarajulu P. Malini T, et al. Biochem Mol Biol Int. 1999 Mar;47(3):537-45. doi: 10.1080/15216549900201573. Biochem Mol Biol Int. 1999. PMID: 10204091
Piperine treatment depleted the total lipid content which was mainly due to the diminution of the total phospholipid concentration. All the classes of phospholipids were decreased markedly following high dose piperine treatment. In contrast, a marked increase …
Piperine treatment depleted the total lipid content which was mainly due to the diminution of the total phospholipid concentra …
Fenofibrate ameliorated atorvastatin and piperine-induced ROS mediated reproductive toxicity in male Wistar rats.
Ghosh S, Sarkar S, Biswas M. Ghosh S, et al. Toxicol Rep. 2024 Dec 10;14:101861. doi: 10.1016/j.toxrep.2024.101861. eCollection 2025 Jun. Toxicol Rep. 2024. PMID: 39758804 Free PMC article.
Atorvastatin and fenofibrate are well-known lipid-lowering drugs. Atorvastatin acts by reducing the production of cholesterol through the inhibition of the 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMG Co-A reductase) enzyme, whereas fenofibrate is a PPAR-al …
Atorvastatin and fenofibrate are well-known lipid-lowering drugs. Atorvastatin acts by reducing the production of cholesterol …
Nano-cocrystals of piperine-succinic acid and its antihyperlipidemic effect in male Wistar rats.
Fitriani L, Hidayah N, Agustin R, Badriyya E, Zaini E. Fitriani L, et al. Pak J Pharm Sci. 2026 Aug;39(8):2461-2471. doi: 10.36721/PJPS.2026.39.8.231.1. Pak J Pharm Sci. 2026. PMID: 42262205
However, piperine exhibits poor solubility and impairs pharmacological effectiveness. OBJECTIVES: The aim of the study was to develop piperine-succinic acid nano-cocrystals and to investigate their efficacy in reducing serum cholesterol and triglyceride level …
However, piperine exhibits poor solubility and impairs pharmacological effectiveness. OBJECTIVES: The aim of the study was to develop …
Hypolipidemic effects of a new piperine derivative GB-N from Piper longum in high-fat diet-fed rats.
Bao L, Bai S, Borijihan G. Bao L, et al. Pharm Biol. 2012 Aug;50(8):962-7. doi: 10.3109/13880209.2012.654395. Epub 2012 Apr 12. Pharm Biol. 2012. PMID: 22494195 Free article.
OBJECTIVE: To investigate the hypolipidemic effects of a new piperine derivative GB-N isolated from long pepper in high-fat diet-fed rats. METHODS: The levels of serum total cholesterol, triacylglycerols (TG), low-density lipoprotein cholesterol (LDL-C …
OBJECTIVE: To investigate the hypolipidemic effects of a new piperine derivative GB-N isolated from long pepper in high-fat diet-fed …
Mitigating efficacy of piperine in the physiological derangements of high fat diet induced obesity in Sprague Dawley rats.
BrahmaNaidu P, Nemani H, Meriga B, Mehar SK, Potana S, Ramgopalrao S. BrahmaNaidu P, et al. Chem Biol Interact. 2014 Sep 25;221:42-51. doi: 10.1016/j.cbi.2014.07.008. Epub 2014 Jul 31. Chem Biol Interact. 2014. PMID: 25087745
This study was aimed to evaluate anti-obesity effects of piperine on high fat diet (HFD) induced obesity in rats. Piperine was isolated from methanolic extract of Piper nigrum by using column chromatography and confirmed by LC-MS analysis. Male SD rats …
This study was aimed to evaluate anti-obesity effects of piperine on high fat diet (HFD) induced obesity in rats. Piperine …
Piperine modulates isoproterenol induced myocardial ischemia through antioxidant and anti-dyslipidemic effect in male Wistar rats.
Dhivya V, Priya LB, Chirayil HT, Sathiskumar S, Huang CY, Padma VV. Dhivya V, et al. Biomed Pharmacother. 2017 Mar;87:705-713. doi: 10.1016/j.biopha.2017.01.002. Epub 2017 Jan 12. Biomed Pharmacother. 2017. PMID: 28088738
Isoproterenol (ISO) induced myocardial infarction and the protection offered by piperine was investigated in the present report. Lipid profile analysis by determining the levels of cholesterol, phospholipids, triglycerides and lipoproteins in serum and heart …
Isoproterenol (ISO) induced myocardial infarction and the protection offered by piperine was investigated in the present report. L …
Efficacy of piperine, an alkaloidal constituent from Piper nigrum on erythrocyte antioxidant status in high fat diet and antithyroid drug induced hyperlipidemic rats.
Vijayakumar RS, Nalini N. Vijayakumar RS, et al. Cell Biochem Funct. 2006 Nov-Dec;24(6):491-8. doi: 10.1002/cbf.1331. Cell Biochem Funct. 2006. PMID: 16927417
The main aim of this study was to investigate the effect of piperine on erythrocyte antioxidant status in high fat diet (HFD) and antithyroid drug induced hyperlipidemic rats. ...Significantly increased osmotic fragility, total cholesterol/phospholipid ratio, …
The main aim of this study was to investigate the effect of piperine on erythrocyte antioxidant status in high fat diet (HFD) and ant …
Characterization and interactions between piperine and ezetimibe in their Anti-hyperlipidemic efficacy using Biopharmaceutics and Pharmacokinetics.
Marati K, Palatheeya S, Chettupalli AK, Naik Bukke SP. Marati K, et al. BMC Pharmacol Toxicol. 2025 Jan 14;26(1):7. doi: 10.1186/s40360-025-00836-z. BMC Pharmacol Toxicol. 2025. PMID: 39810264 Free PMC article.
The objective of this study was to increase the bioavailability of EZ while also improving its potency and reducing its toxicity by using piperine as a bioenhancer. Therefore, rats were given piperine combined with EZ, and their antihyperlipidemic activity wa …
The objective of this study was to increase the bioavailability of EZ while also improving its potency and reducing its toxicity by using …
26 results