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Cryptic inhibitory regions nearby activation domains.

Knight A, Piskacek M. Knight A, et al. Among authors: piskacek m. Biochimie. 2022 May 10;200:19-26. doi: 10.1016/j.biochi.2022.05.004. Online ahead of print. Biochimie. 2022. PMID: 35561946

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Clozapine Reverses Dysfunction of Glutamatergic Neurons Derived From Clozapine-Responsive Schizophrenia Patients.

Hribkova H, Svoboda O, Bartecku E, Zelinkova J, Horinkova J, Lacinova L, Piskacek M, Lipovy B, Provaznik I, Glover JC, Kasparek T, Sun YM. Hribkova H, et al. Among authors: piskacek m. Front Cell Neurosci. 2022 Feb 23;16:830757. doi: 10.3389/fncel.2022.830757. eCollection 2022. Front Cell Neurosci. 2022. PMID: 35281293 Free PMC article.

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Blocking of EphA2 on Endometrial Tumor Cells Reduces Susceptibility to Vδ1 Gamma-Delta T-Cell-Mediated Killing.

Hudecek R, Kohlova B, Siskova I, Piskacek M, Knight A. Hudecek R, et al. Among authors: piskacek m. Front Immunol. 2021 Oct 7;12:752646. doi: 10.3389/fimmu.2021.752646. eCollection 2021. Front Immunol. 2021. PMID: 34691070 Free PMC article.

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Plasmacytoid Dendritic Cells in Patients with MGUS and Multiple Myeloma.

Knight A, Rihova L, Kralova R, Penka M, Adam Z, Pour L, Piskacek M, Hajek R. Knight A, et al. Among authors: piskacek m. J Clin Med. 2021 Aug 20;10(16):3717. doi: 10.3390/jcm10163717. J Clin Med. 2021. PMID: 34442012 Free PMC article.

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The 9aaTAD Activation Domains in the Yamanaka Transcription Factors Oct4, Sox2, Myc, and Klf4.

Piskacek M, Otasevic T, Repko M, Knight A. Piskacek M, et al. Stem Cell Rev Rep. 2021 Oct;17(5):1934-1936. doi: 10.1007/s12015-021-10225-8. Epub 2021 Aug 3. Stem Cell Rev Rep. 2021. PMID: 34342803 No abstract available.

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Universal two-point interaction of mediator KIX with 9aaTAD activation domains.

Hofrova A, Lousa P, Kubickova M, Hritz J, Otasevic T, Repko M, Knight A, Piskacek M. Hofrova A, et al. Among authors: piskacek m. J Cell Biochem. 2021 Oct;122(10):1544-1555. doi: 10.1002/jcb.30075. Epub 2021 Jul 5. J Cell Biochem. 2021. PMID: 34224597

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The evolution of the 9aaTAD domain in Sp2 proteins: inactivation with valines and intron reservoirs.

Piskacek M, Havelka M, Jendruchova K, Knight A, Keegan LP. Piskacek M, et al. Cell Mol Life Sci. 2020 May;77(9):1793-1810. doi: 10.1007/s00018-019-03251-w. Epub 2019 Aug 2. Cell Mol Life Sci. 2020. PMID: 31375868

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Nuclear hormone receptors: Ancient 9aaTAD and evolutionally gained NCoA activation pathways.

Piskacek M, Havelka M, Jendruchova K, Knight A. Piskacek M, et al. J Steroid Biochem Mol Biol. 2019 Mar;187:118-123. doi: 10.1016/j.jsbmb.2018.11.008. Epub 2018 Nov 20. J Steroid Biochem Mol Biol. 2019. PMID: 30468856

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The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases.

Fafilek B, Balek L, Bosakova MK, Varecha M, Nita A, Gregor T, Gudernova I, Krenova J, Ghosh S, Piskacek M, Jonatova L, Cernohorsky NH, Zieba JT, Kostas M, Haugsten EM, Wesche J, Erneux C, Trantirek L, Krakow D, Krejci P. Fafilek B, et al. Among authors: piskacek m. Sci Signal. 2018 Sep 18;11(548):eaap8608. doi: 10.1126/scisignal.aap8608. Sci Signal. 2018. PMID: 30228226

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The 9aaTAD Is Exclusive Activation Domain in Gal4.

Piskacek M, Havelka M, Rezacova M, Knight A. Piskacek M, et al. PLoS One. 2017 Jan 5;12(1):e0169261. doi: 10.1371/journal.pone.0169261. eCollection 2017. PLoS One. 2017. PMID: 28056036 Free PMC article.

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