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2002 1
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Page 1
The immunology of smallpox vaccines.
Kennedy RB, Ovsyannikova IG, Jacobson RM, Poland GA. Kennedy RB, et al. Among authors: poland ga. Curr Opin Immunol. 2009 Jun;21(3):314-20. doi: 10.1016/j.coi.2009.04.004. Epub 2009 Jun 11. Curr Opin Immunol. 2009. PMID: 19524427 Free PMC article. Review.
The eradication effort was largely made possible by the availability of an effective vaccine based on the immunologically cross-protective vaccinia virus. Although the concept of vaccination dates back to the late 1800s with Edward Jenner, it is only in the p …
The eradication effort was largely made possible by the availability of an effective vaccine based on the immunologically cross-prote …
Defending against smallpox: a focus on vaccines.
Voigt EA, Kennedy RB, Poland GA. Voigt EA, et al. Among authors: poland ga. Expert Rev Vaccines. 2016 Sep;15(9):1197-211. doi: 10.1080/14760584.2016.1175305. Epub 2016 Apr 28. Expert Rev Vaccines. 2016. PMID: 27049653 Free PMC article. Review.
Concerns remain, however, about the development and use of the smallpox virus as a biological weapon, which necessitates the need for continued vaccine development. Smallpox vaccine development is thus a much-reviewed topic of high interest. Thi …
Concerns remain, however, about the development and use of the smallpox virus as a biological weapon, which necessitates the n …
Cytokine production associated with smallpox vaccine responses.
Simon WL, Salk HM, Ovsyannikova IG, Kennedy RB, Poland GA. Simon WL, et al. Among authors: poland ga. Immunotherapy. 2014;6(10):1097-112. doi: 10.2217/imt.14.72. Immunotherapy. 2014. PMID: 25428648 Free PMC article. Review.
Smallpox was eradicated 34 years ago due to the success of the smallpox vaccine; yet, the vaccine continues to be studied because of its importance in responding to potential biological warfare and the adverse events associated with current smallpox …
Smallpox was eradicated 34 years ago due to the success of the smallpox vaccine; yet, the vaccine continues to b …
Smallpox vaccine: problems and prospects.
Poland GA, Neff JM. Poland GA, et al. Immunol Allergy Clin North Am. 2003 Nov;23(4):731-43. doi: 10.1016/s0889-8561(03)00096-1. Immunol Allergy Clin North Am. 2003. PMID: 14753389 Review.
Smallpox justifiably is feared because of its morbidity and mortality. Wide-spread population-level susceptibility to smallpox exists, and the only effective tool against the virus is a live, attenuated vaccine that is highly reactogenic and controvers …
Smallpox justifiably is feared because of its morbidity and mortality. Wide-spread population-level susceptibility to smallpox …
Application of pharmacogenomics to vaccines.
Poland GA, Ovsyannikova IG, Jacobson RM. Poland GA, et al. Pharmacogenomics. 2009 May;10(5):837-52. doi: 10.2217/pgs.09.25. Pharmacogenomics. 2009. PMID: 19450131 Free PMC article. Review.
This paper discusses the hypothesis of the 'immune response gene network' and genetic (and bioinformatic) strategies to study associations between immune response gene polymorphisms and variations in humoral and cellular immune responses to prophylactic viral vaccines, suc …
This paper discusses the hypothesis of the 'immune response gene network' and genetic (and bioinformatic) strategies to study associations b …
Proteomic assessment of humoral immune responses in smallpox vaccine recipients.
Kennedy RB, Ovsyannikova IG, Haralambieva IH, Grill DE, Poland GA. Kennedy RB, et al. Among authors: poland ga. Vaccine. 2022 Jan 31;40(5):789-797. doi: 10.1016/j.vaccine.2021.12.033. Epub 2021 Dec 21. Vaccine. 2022. PMID: 34952760 Free PMC article.
The availability of effective smallpox vaccines was a critical element of the successful eradication of smallpox in 1980. ...In this cohort, which consisted of both ACAM2000 and Dryvax recipients, we noted minute differences in the antibody responses to a res …
The availability of effective smallpox vaccines was a critical element of the successful eradication of smallpox in 198 …
The US smallpox vaccination program: a review of a large modern era smallpox vaccination implementation program.
Poland GA, Grabenstein JD, Neff JM. Poland GA, et al. Vaccine. 2005 Mar 18;23(17-18):2078-81. doi: 10.1016/j.vaccine.2005.01.012. Vaccine. 2005. PMID: 15755574 Review.
We describe the US experience with a large-scale smallpox vaccination program in the modern era and quantify the anticipated and unanticipated local and systemic side-effects of smallpox vaccination. ...These results constitute the largest dataset of a …
We describe the US experience with a large-scale smallpox vaccination program in the modern era and quantify the anticipated a …
Prevention of monkeypox with vaccines: a rapid review.
Poland GA, Kennedy RB, Tosh PK. Poland GA, et al. Lancet Infect Dis. 2022 Dec;22(12):e349-e358. doi: 10.1016/S1473-3099(22)00574-6. Epub 2022 Sep 15. Lancet Infect Dis. 2022. PMID: 36116460 Free PMC article. Review.
These data are supported by a large number of animal studies (primarily in non-human primates) with live virus challenge by various inoculation routes. These studies uniformly showed a high degree of protection and immunity against monkeypox virus following vacci …
These data are supported by a large number of animal studies (primarily in non-human primates) with live virus challenge by various i …
Smallpox vaccines for biodefense.
Kennedy RB, Ovsyannikova I, Poland GA. Kennedy RB, et al. Among authors: poland ga. Vaccine. 2009 Nov 5;27 Suppl 4:D73-9. doi: 10.1016/j.vaccine.2009.07.103. Vaccine. 2009. PMID: 19837292 Free PMC article. Review.
With fatality rates up to 30%, smallpox left its survivors with extensive scarring and other serious sequelae. It is estimated that smallpox killed 500 million people in the 19th and 20th centuries. Given the ongoing concerns regarding the use of variola as a …
With fatality rates up to 30%, smallpox left its survivors with extensive scarring and other serious sequelae. It is estimated that …
53 results