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Epicutaneous Allergic Sensitization by Cooperation between Allergen Protease Activity and Mechanical Skin Barrier Damage in Mice.
Shimura S, Takai T, Iida H, Maruyama N, Ochi H, Kamijo S, Nishioka I, Hara M, Matsuda A, Saito H, Nakae S, Ogawa H, Okumura K, Ikeda S. Shimura S, et al. J Invest Dermatol. 2016 Jul;136(7):1408-1417. doi: 10.1016/j.jid.2016.02.810. Epub 2016 Mar 14. J Invest Dermatol. 2016. PMID: 26987428 Free article.
Allergen sources such as mites, insects, fungi, and pollen contain proteases. Airway exposure to proteases induces allergic airway inflammation and IgE/IgG1 responses via IL-33-dependent mechanisms in mice. ...These results suggest that allergen source …
Allergen sources such as mites, insects, fungi, and pollen contain proteases. Airway exposure to proteases induces a
Barrier dysfunction caused by environmental proteases in the pathogenesis of allergic diseases.
Takai T, Ikeda S. Takai T, et al. Allergol Int. 2011 Mar;60(1):25-35. doi: 10.2332/allergolint.10-RAI-0273. Epub 2011 Dec 25. Allergol Int. 2011. PMID: 21173566 Free article. Review.
Skin barrier dysfunction has emerged as a critical driving force in the initiation and exacerbation of atopic dermatitis and the "atopic march" in allergic diseases. ...Sources of allergens such as mites, cockroaches, fungi, and pollen
Skin barrier dysfunction has emerged as a critical driving force in the initiation and exacerbation of atopic dermat
Analysis of Results of Specific IgE in 100 Atopic Dermatitis Patients with the Use of Multiplex Examination ALEX2-Allergy Explorer.
Čelakovská J, Bukač J, Cermákova E, Vaňková R, Skalská H, Krejsek J, Andrýs C. Čelakovská J, et al. Int J Mol Sci. 2021 May 17;22(10):5286. doi: 10.3390/ijms22105286. Int J Mol Sci. 2021. PMID: 34067936 Free PMC article.
Our study analyses the results of specific IgE to 295 allergen reagents (117 allergenic extracts and 178 molecular components) in patients suffering from atopic dermatitis (AD) with the use of ALEX2 Allergy Explorer. METHOD: The complete dermatological and allergolo …
Our study analyses the results of specific IgE to 295 allergen reagents (117 allergenic extracts and 178 molecular components) in patients s …