Epicutaneous Allergic Sensitization by Cooperation between Allergen Protease Activity and Mechanical Skin Barrier Damage in Mice.
Shimura S, Takai T, Iida H, Maruyama N, Ochi H, Kamijo S, Nishioka I, Hara M, Matsuda A, Saito H, Nakae S, Ogawa H, Okumura K, Ikeda S.
Shimura S, et al.
J Invest Dermatol. 2016 Jul;136(7):1408-1417. doi: 10.1016/j.jid.2016.02.810. Epub 2016 Mar 14.
J Invest Dermatol. 2016.
PMID: 26987428
Free article.
Allergen sources such as mites, insects, fungi, and pollen contain proteases. Airway exposure to proteases induces allergic airway inflammation and IgE/IgG1 responses via IL-33-dependent mechanisms in mice. ...These results suggest that allergen source …
Allergen sources such as mites, insects, fungi, and pollen contain proteases. Airway exposure to proteases induces a …