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The genus Polygonatum: A review of ethnopharmacology, phytochemistry and pharmacology.
Zhao P, Zhao C, Li X, Gao Q, Huang L, Xiao P, Gao W. Zhao P, et al. J Ethnopharmacol. 2018 Mar 25;214:274-291. doi: 10.1016/j.jep.2017.12.006. Epub 2017 Dec 12. J Ethnopharmacol. 2018. PMID: 29246502 Review.
A putative biosynthetic pathway of steroidal saponins and triterpenoid saponins has been established based on the compounds isolated from Polygonatum plants. The crude extracts and certain pure compounds from Polygonatum plants have shown a wide range of pharmacolog …
A putative biosynthetic pathway of steroidal saponins and triterpenoid saponins has been established based on the compounds isolated from …
Advances in Mechanism Research on Polygonatum in Prevention and Treatment of Diabetes.
Liu S, Jia QJ, Peng YQ, Feng TH, Hu ST, Dong JE, Liang ZS. Liu S, et al. Front Pharmacol. 2022 Feb 8;13:758501. doi: 10.3389/fphar.2022.758501. eCollection 2022. Front Pharmacol. 2022. PMID: 35211009 Free PMC article. Review.
Diabetes mellitus is a fast-growing disease with a major influence on people's quality of life. ...However, the research on the mechanism of these three Polygonatum spp. in diabetes has not been reviewed. This review provides a summary of the research …
Diabetes mellitus is a fast-growing disease with a major influence on people's quality of life. ...However, the research on th …
A Review: The Bioactivities and Pharmacological Applications of Polygonatum sibiricum polysaccharides.
Cui X, Wang S, Cao H, Guo H, Li Y, Xu F, Zheng M, Xi X, Han C. Cui X, et al. Molecules. 2018 May 14;23(5):1170. doi: 10.3390/molecules23051170. Molecules. 2018. PMID: 29757991 Free PMC article. Review.
Traditional Chinese Medicine (TCM) has been widely used in China and is regarded as the most important therapeutic. Polygonatum sibiricum (PS), a natural plant used in traditional Chinese medicine, has various functions associated with a number of its components. ...Of the …
Traditional Chinese Medicine (TCM) has been widely used in China and is regarded as the most important therapeutic. Polygonatum sibir …
Effects of Polygonatum sibiricum saponin on hyperglycemia, gut microbiota composition and metabolic profiles in type 2 diabetes mice.
Chai Y, Luo J, Bao Y. Chai Y, et al. Biomed Pharmacother. 2021 Nov;143:112155. doi: 10.1016/j.biopha.2021.112155. Epub 2021 Sep 10. Biomed Pharmacother. 2021. PMID: 34517283 Free article.
Diabetes is a global disease that endangers human health. As reported, saponins are effective bioactive compounds for treating type 2 diabetes mellitus (T2DM) and have nontoxic side effects. This study aimed to examine the hypoglycemic effects of Polygonat …
Diabetes is a global disease that endangers human health. As reported, saponins are effective bioactive compounds for treating type 2 …
Polysaccharides from Polygonatum kingianum improve glucose and lipid metabolism in rats fed a high fat diet.
Gu W, Wang Y, Zeng L, Dong J, Bi Q, Yang X, Che Y, He S, Yu J. Gu W, et al. Biomed Pharmacother. 2020 May;125:109910. doi: 10.1016/j.biopha.2020.109910. Epub 2020 Feb 3. Biomed Pharmacother. 2020. PMID: 32028238 Free article.
OBJECTIVE: Polygonatum kingianum is a traditional Chinese medicine commonly used to treat diabetes and hyperlipidemia. Polysaccharides from Polygonatum kingianum could regulate glucose and lipid metabolism in high-fat diet (HFD) rats. ...
OBJECTIVE: Polygonatum kingianum is a traditional Chinese medicine commonly used to treat diabetes and hyperlipidemia. Polysac …
Polygonatum sibiricum polysaccharide potentially attenuates diabetic retinal injury in a diabetic rat model.
Wang Y, Lan C, Liao X, Chen D, Song W, Zhang Q. Wang Y, et al. J Diabetes Investig. 2019 Jul;10(4):915-924. doi: 10.1111/jdi.12976. Epub 2018 Dec 16. J Diabetes Investig. 2019. PMID: 30426692 Free PMC article.
AIMS/INTRODUCTION: To investigate the protective effect of Polygonatum sibiricum polysaccharide (PSP) on the retina in diabetic rats. MATERIALS AND METHODS: A total of 120 Sprague-Dawley rats were randomly divided into blank control, control model (meaning diabet …
AIMS/INTRODUCTION: To investigate the protective effect of Polygonatum sibiricum polysaccharide (PSP) on the retina in diabetic …
[Research on anti-tumor natural product diosgenin].
Zhang SQ, Song YX, Zhang WX, Chen MJ, Man SL. Zhang SQ, et al. Zhongguo Zhong Yao Za Zhi. 2021 Sep;46(17):4360-4366. doi: 10.19540/j.cnki.cjcmm.20210610.701. Zhongguo Zhong Yao Za Zhi. 2021. PMID: 34581038 Review. Chinese.
Diosgenin is widely distributed in many plants, such as Polygonatum sibiricum, Paris polyphylla, Dioscorea oppositifolia, Trigonella foenum-graecum, Costus speciosus, Tacca chantrieri, which has good anti-tumor activity and preferable effects on preventing atherosclerosis, …
Diosgenin is widely distributed in many plants, such as Polygonatum sibiricum, Paris polyphylla, Dioscorea oppositifolia, Trigonella …
Original Research: Potential ocular protection and dynamic observation of Polygonatum sibiricum polysaccharide against streptozocin-induced diabetic rats' model.
Wang Y, Qin S, Pen G, Chen D, Han C, Miao C, Lu B, Su C, Feng S, Li W, Han J, Cho NC, Si Y. Wang Y, et al. Exp Biol Med (Maywood). 2017 Jan;242(1):92-101. doi: 10.1177/1535370216663866. Epub 2016 Aug 9. Exp Biol Med (Maywood). 2017. PMID: 27510582 Free PMC article.
The purpose of the study is to evaluate the protective effect of Polygonatum sibiricum polysaccharide, an important component of Polygonatum sibiricum, on ocular complications in streptozotocin-induced diabetes mellitus rats. ...In conclusion, these re …
The purpose of the study is to evaluate the protective effect of Polygonatum sibiricum polysaccharide, an important component of P …
Polygonatum sibiricum polysaccharide inhibits high glucose-induced oxidative stress, inflammatory response, and apoptosis in RPE cells.
Wang W, Li S, Song M. Wang W, et al. J Recept Signal Transduct Res. 2022 Apr;42(2):189-196. doi: 10.1080/10799893.2021.1883061. Epub 2021 Feb 8. J Recept Signal Transduct Res. 2022. PMID: 33554697
Diabetic retinopathy is one of the major diabetic complications and remains the most common cause of adult blindness among patients with diabetes mellitus. Polygonatum sibiricum polysaccharides (PSP) are a group important component of Polygon …
Diabetic retinopathy is one of the major diabetic complications and remains the most common cause of adult blindness among pat …
Polysaccharide-rich extract from Polygonatum sibiricum protects hematopoiesis in bone marrow suppressed by triple negative breast cancer.
Xie Y, Jiang Z, Yang R, Ye Y, Pei L, Xiong S, Wang S, Wang L, Liu S. Xie Y, et al. Biomed Pharmacother. 2021 May;137:111338. doi: 10.1016/j.biopha.2021.111338. Epub 2021 Feb 9. Biomed Pharmacother. 2021. PMID: 33578234 Free article.
Polysaccharide is one of main components in Polygonatum sibiricum (PS), which is an herbal medicine widely used in East Asia. Polysaccharides from Polygonatum sibiricum has been shown to exhibit multiple biological activities, such as anti-diabetes, anti-infl …
Polysaccharide is one of main components in Polygonatum sibiricum (PS), which is an herbal medicine widely used in East Asia. Polysac …
44 results