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The genus Polygonatum: A review of ethnopharmacology, phytochemistry and pharmacology.

Zhao P, Zhao C, Li X, Gao Q, Huang L, Xiao P, Gao W. Zhao P, et al. J Ethnopharmacol. 2018 Mar 25;214:274-291. doi: 10.1016/j.jep.2017.12.006. Epub 2017 Dec 12. J Ethnopharmacol. 2018. PMID: 29246502 Review.

A putative biosynthetic pathway of steroidal saponins and triterpenoid saponins has been established based on the compounds isolated from Polygonatum plants. The crude extracts and certain pure compounds from Polygonatum plants have shown a wide range of pharmacolog …

A putative biosynthetic pathway of steroidal saponins and triterpenoid saponins has been established based on the compounds isolated from …

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A Review: The Bioactivities and Pharmacological Applications of Polygonatum sibiricum polysaccharides.

Cui X, Wang S, Cao H, Guo H, Li Y, Xu F, Zheng M, Xi X, Han C. Cui X, et al. Molecules. 2018 May 14;23(5):1170. doi: 10.3390/molecules23051170. Molecules. 2018. PMID: 29757991 Free PMC article. Review.

Traditional Chinese Medicine (TCM) has been widely used in China and is regarded as the most important therapeutic. Polygonatum sibiricum (PS), a natural plant used in traditional Chinese medicine, has various functions associated with a number of its components. ...Of the …

Traditional Chinese Medicine (TCM) has been widely used in China and is regarded as the most important therapeutic. Polygonatum sibir …

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Polygonatum sibiricum polysaccharide potentially attenuates diabetic retinal injury in a diabetic rat model.

Wang Y, Lan C, Liao X, Chen D, Song W, Zhang Q. Wang Y, et al. J Diabetes Investig. 2019 Jul;10(4):915-924. doi: 10.1111/jdi.12976. Epub 2018 Dec 16. J Diabetes Investig. 2019. PMID: 30426692 Free PMC article.

AIMS/INTRODUCTION: To investigate the protective effect of Polygonatum sibiricum polysaccharide (PSP) on the retina in diabetic rats. MATERIALS AND METHODS: A total of 120 Sprague-Dawley rats were randomly divided into blank control, control model (meaning diabet …

AIMS/INTRODUCTION: To investigate the protective effect of Polygonatum sibiricum polysaccharide (PSP) on the retina in diabetic …

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Polysaccharides from Polygonatum kingianum improve glucose and lipid metabolism in rats fed a high fat diet.

Gu W, Wang Y, Zeng L, Dong J, Bi Q, Yang X, Che Y, He S, Yu J. Gu W, et al. Biomed Pharmacother. 2020 May;125:109910. doi: 10.1016/j.biopha.2020.109910. Epub 2020 Feb 3. Biomed Pharmacother. 2020. PMID: 32028238 Free article.

OBJECTIVE: Polygonatum kingianum is a traditional Chinese medicine commonly used to treat diabetes and hyperlipidemia. Polysaccharides from Polygonatum kingianum could regulate glucose and lipid metabolism in high-fat diet (HFD) rats. ...

OBJECTIVE: Polygonatum kingianum is a traditional Chinese medicine commonly used to treat diabetes and hyperlipidemia. Polysac …

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Original Research: Potential ocular protection and dynamic observation of Polygonatum sibiricum polysaccharide against streptozocin-induced diabetic rats' model.

Wang Y, Qin S, Pen G, Chen D, Han C, Miao C, Lu B, Su C, Feng S, Li W, Han J, Cho NC, Si Y. Wang Y, et al. Exp Biol Med (Maywood). 2017 Jan;242(1):92-101. doi: 10.1177/1535370216663866. Epub 2016 Aug 9. Exp Biol Med (Maywood). 2017. PMID: 27510582 Free PMC article.

The purpose of the study is to evaluate the protective effect of Polygonatum sibiricum polysaccharide, an important component of Polygonatum sibiricum, on ocular complications in streptozotocin-induced diabetes mellitus rats. ...In conclusion, these re …

The purpose of the study is to evaluate the protective effect of Polygonatum sibiricum polysaccharide, an important component of P …

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Hypoglycemic effects and modulation of gut microbiota of diabetic mice by saponin from Polygonatum sibiricum.

Luo J , Chai Y , Zhao M , Guo Q , Bao Y . Luo J , et al. Food Funct. 2020 May 1;11(5):4327-4338. doi: 10.1039/d0fo00428f. Epub 2020 May 5. Food Funct. 2020. PMID: 32367101

Saponin is one of the biologically active components of Polygonatum sibiricum. This study aimed to extract saponin from Polygonatum sibiricum (PSS) and to investigate its hypoglycemic effect and effect on gut micorbiota in diabetic mice. ...In summary, PSS ma …

Saponin is one of the biologically active components of Polygonatum sibiricum. This study aimed to extract saponin from Polygonatu …

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Syringaresinol-di-O-beta-D-glucoside, a phenolic compound from Polygonatum sibiricum, exhibits an antidiabetic and antioxidative effect on a streptozotocin-induced mouse model of diabetes.

Zhai L, Wang X. Zhai L, et al. Mol Med Rep. 2018 Dec;18(6):5511-5519. doi: 10.3892/mmr.2018.9580. Epub 2018 Oct 23. Mol Med Rep. 2018. PMID: 30365054 Free PMC article.

Syringaresinol-di-O-beta-D-glucoside (SOG) is a phenolic compound extracted from Polygonatum sibiricum. The present study aimed to investigate the antidiabetic effect of SOG on streptozocin (STZ)-induced diabetic mice and determine the potential underlying mechanism …

Syringaresinol-di-O-beta-D-glucoside (SOG) is a phenolic compound extracted from Polygonatum sibiricum. The present study aimed to in …

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Comparative transcriptomic analysis of rhizomes, stems, and leaves of Polygonatum odoratum (Mill.) Druce reveals candidate genes associated with polysaccharide synthesis.

Zhang S, Shi Y, Huang L, Wang C, Zhao D, Ma K, Wu J, Peng D. Zhang S, et al. Gene. 2020 Jun 20;744:144626. doi: 10.1016/j.gene.2020.144626. Epub 2020 Mar 26. Gene. 2020. PMID: 32224272

Polygonatum odoratum (Mill.) Druce is a well-known traditional Chinese herb. Polysaccharides are major bioactive components of Polygonatum odoratum, which can improve immunity, and are used to treat rheumatic heart disease, cardiovascular disease, and diabetes …

Polygonatum odoratum (Mill.) Druce is a well-known traditional Chinese herb. Polysaccharides are major bioactive components of Pol …

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Colletotrichum spaethianum Causing Anthracnose on Polygonatum cyrtonema Hua in Anhui Province, China.

Ma J, Xiao X, Wang X, Guo M. Ma J, et al. Plant Dis. 2020 Aug 20. doi: 10.1094/PDIS-04-20-0778-PDN. Online ahead of print. Plant Dis. 2020. PMID: 32815485 Free article.

Polygonatum cyrtonema Hua, also known as Huangjing, is an important traditional Chinese herb for treating diabetes and asthma. ...The same pathogen was reisolated and confirmed as C. spaethianum by sequencing of ITS, GAPDH and Tub2, fulfilling Koch's postulates. Pre …

Polygonatum cyrtonema Hua, also known as Huangjing, is an important traditional Chinese herb for treating diabetes and asthma. …

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Structural characterization, hypoglycemic effects and antidiabetic mechanism of a novel polysaccharides from Polygonatum kingianum Coll. et Hemsl.

Li R, Tao A, Yang R, Fan M, Zhang X, Du Z, Shang F, Xia C, Duan B. Li R, et al. Biomed Pharmacother. 2020 Nov;131:110687. doi: 10.1016/j.biopha.2020.110687. Epub 2020 Sep 25. Biomed Pharmacother. 2020. PMID: 33152904 Free article.

The rhizome of Polygonatum kingianum has been used as a traditional medicine in China. ...The hypoglycemic activity of PKPs-1was investigated by in vitro assay with the HepG2 cell line and in vivo test using STZ-induced diabetic mice. Results showed that the average …

The rhizome of Polygonatum kingianum has been used as a traditional medicine in China. ...The hypoglycemic activity of PKPs-1was inve …

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