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Advances in Mechanism Research on Polygonatum in Prevention and Treatment of Diabetes.
Liu S, Jia QJ, Peng YQ, Feng TH, Hu ST, Dong JE, Liang ZS. Liu S, et al. Front Pharmacol. 2022 Feb 8;13:758501. doi: 10.3389/fphar.2022.758501. eCollection 2022. Front Pharmacol. 2022. PMID: 35211009 Free PMC article. Review.
Diabetes mellitus is a fast-growing disease with a major influence on people's quality of life. ...However, the research on the mechanism of these three Polygonatum spp. in diabetes has not been reviewed. This review provides a summary of the research …
Diabetes mellitus is a fast-growing disease with a major influence on people's quality of life. ...However, the research on th …
A Review: The Bioactivities and Pharmacological Applications of Polygonatum sibiricum polysaccharides.
Cui X, Wang S, Cao H, Guo H, Li Y, Xu F, Zheng M, Xi X, Han C. Cui X, et al. Molecules. 2018 May 14;23(5):1170. doi: 10.3390/molecules23051170. Molecules. 2018. PMID: 29757991 Free PMC article. Review.
Traditional Chinese Medicine (TCM) has been widely used in China and is regarded as the most important therapeutic. Polygonatum sibiricum (PS), a natural plant used in traditional Chinese medicine, has various functions associated with a number of its components. ...Of the …
Traditional Chinese Medicine (TCM) has been widely used in China and is regarded as the most important therapeutic. Polygonatum sibir …
Research progress on medicinal components and pharmacological activities of polygonatum sibiricum.
Liu R, Zhang X, Cai Y, Xu S, Xu Q, Ling C, Li X, Li W, Liu P, Liu W. Liu R, et al. J Ethnopharmacol. 2024 Jun 28;328:118024. doi: 10.1016/j.jep.2024.118024. Epub 2024 Mar 13. J Ethnopharmacol. 2024. PMID: 38484952 Review.
RESULTS: Several studies have demonstrated the strong antioxidant properties of polygonatum extract, which can be attributed to the presence of flavonoids and other polyphenol compounds; for diabetes and other metabolic-related diseases, polygonatum saponins …
RESULTS: Several studies have demonstrated the strong antioxidant properties of polygonatum extract, which can be attributed to the p …
The genus Polygonatum: A review of ethnopharmacology, phytochemistry and pharmacology.
Zhao P, Zhao C, Li X, Gao Q, Huang L, Xiao P, Gao W. Zhao P, et al. J Ethnopharmacol. 2018 Mar 25;214:274-291. doi: 10.1016/j.jep.2017.12.006. Epub 2017 Dec 12. J Ethnopharmacol. 2018. PMID: 29246502 Review.
A putative biosynthetic pathway of steroidal saponins and triterpenoid saponins has been established based on the compounds isolated from Polygonatum plants. The crude extracts and certain pure compounds from Polygonatum plants have shown a wide range of pharmacolog …
A putative biosynthetic pathway of steroidal saponins and triterpenoid saponins has been established based on the compounds isolated from …
Bioactive compounds from Polygonatum genus as anti-diabetic agents with future perspectives.
Shi Y, Si D, Chen D, Zhang X, Han Z, Yu Q, Liu J, Si J. Shi Y, et al. Food Chem. 2023 May 15;408:135183. doi: 10.1016/j.foodchem.2022.135183. Epub 2022 Dec 12. Food Chem. 2023. PMID: 36566543 Free article. Review.
Diabetes mellitus (DM) is one of the most serious health problems worldwide. Species in the genus Polygonatum are traditional food and medicinal plants, which play an important role in controlling blood glucose. In this reveiw, we systematically summarized th …
Diabetes mellitus (DM) is one of the most serious health problems worldwide. Species in the genus Polygonatum are tradi …
Polygonatum sibiricum saponin Exerts Beneficial Hypoglycemic Effects in Type 2 Diabetes Mice by Improving Hepatic Insulin Resistance and Glycogen Synthesis-Related Proteins.
Chen Z, Luo J, Jia M, Chai Y, Bao Y. Chen Z, et al. Nutrients. 2022 Dec 8;14(24):5222. doi: 10.3390/nu14245222. Nutrients. 2022. PMID: 36558381 Free PMC article.
Type 2 diabetes mellitus (T2DM) is a systemic metabolic disorder characterized by insulin deficiency and insulin resistance. Recently, it has become a significant threat to public health. Polygonatum sibiricum saponin (PSS) has potential hypoglycemic effects, …
Type 2 diabetes mellitus (T2DM) is a systemic metabolic disorder characterized by insulin deficiency and insulin resistance. R …
Integrated 16S rRNA Sequencing and Untargeted Metabolomics Analysis to Reveal the Protective Mechanisms of Polygonatum sibiricum Polysaccharide on Type 2 Diabetes Mellitus Model Rats.
Zhang H, Li H, Pan B, Zhang S, Su X, Sun W, Zhang T, Zhang Z, Lv S, Cui H. Zhang H, et al. Curr Drug Metab. 2023;24(4):270-282. doi: 10.2174/1389200224666230406114012. Curr Drug Metab. 2023. PMID: 37038712
BACKGROUND: Polygonatum sibiricum polysaccharide (PSP) can improve insulin resistance and inhibit oxidative stress. However, the detailed anti-diabetic mechanism of PSP is still poorly defined. METHODS: In this study, the anti-diabetic, anti-inflammatory and …
BACKGROUND: Polygonatum sibiricum polysaccharide (PSP) can improve insulin resistance and inhibit oxidative stress. However, the deta …
Mechanisms of action and applications of Polygonatum sibiricum polysaccharide at the intestinal mucosa barrier: a review.
Ren Y, Sun Y, Liao YY, Wang S, Liu Q, Duan CY, Sun L, Li XY, Yuan JL. Ren Y, et al. Front Pharmacol. 2024 Aug 19;15:1421607. doi: 10.3389/fphar.2024.1421607. eCollection 2024. Front Pharmacol. 2024. PMID: 39224782 Free PMC article. Review.
As a medicinal and edible homologous Chinese herb, Polygonatum sibiricum has been used as a primary ingredient in various functional and medicinal products. Damage to the intestinal mucosal barrier can lead to or worsen conditions such as type 2 diabetes and Alzheim …
As a medicinal and edible homologous Chinese herb, Polygonatum sibiricum has been used as a primary ingredient in various functional …
Advances in Polygonatum sibiricum polysaccharides: Extraction, purification, structure, biosynthesis, and bioactivity.
Liu D, Tang W, Han C, Nie S. Liu D, et al. Front Nutr. 2022 Dec 5;9:1074671. doi: 10.3389/fnut.2022.1074671. eCollection 2022. Front Nutr. 2022. PMID: 36545471 Free PMC article. Review.
Polygonatum sibiricum has been used as food and medicine for thousands of years, and P. sibiricum polysaccharides (PSPs) have become the hot research spot due to their various health-promoting functions. ...Notably, it is concluded that PSPs mainly contain several types of …
Polygonatum sibiricum has been used as food and medicine for thousands of years, and P. sibiricum polysaccharides (PSPs) have become …
Therapeutic potential of genus Polygonatum in common neuropsychiatric disorders: The revival of an ancient remedy in modern medicine.
Li B, Wang J, Wang B, Wang X, Zhu G, Yang S. Li B, et al. J Ethnopharmacol. 2025 Jun 26;350:120052. doi: 10.1016/j.jep.2025.120052. Epub 2025 May 27. J Ethnopharmacol. 2025. PMID: 40441463 Review.
Modern studies have substantiated its pharmacological properties, including anti-aging, neuroprotective, immunomodulatory, anti-diabetic, memory-enhancing, anti-inflammatory, and antioxidant effects. Recently, research on Polygonatum in the neuropsychiatric disorder …
Modern studies have substantiated its pharmacological properties, including anti-aging, neuroprotective, immunomodulatory, anti-diabetic …
70 results