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Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
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Double-blinded randomised placebo controlled trial of enterosgel (polymethylsiloxane polyhydrate) for the treatment of IBS with diarrhoea (IBS-D).
Howell CA, Kemppinen A, Allgar V, Dodd M, Knowles CH, McLaughlin J, Pandya P, Whorwell P, Markaryan E, Yiannakou Y. Howell CA, et al. Gut. 2022 Dec;71(12):2430-2438. doi: 10.1136/gutjnl-2022-327293. Epub 2022 Jun 27. Gut. 2022. PMID: 35760493 Free PMC article. Clinical Trial.
OBJECTIVE: Irritable bowel syndrome with diarrhoea (IBS-D) is a common and challenging condition that significantly reduces quality of life. Enterosgel (polymethylsiloxane polyhydrate) is an intestinal adsorbent which sequesters harmful molecules and is safe and eff …
OBJECTIVE: Irritable bowel syndrome with diarrhoea (IBS-D) is a common and challenging condition that significantly reduces quality of life. …
Randomised feasibility study of an intestinal adsorbent in acute diarrhoea in The Gambia.
Rahden P, Fatty A, Jobarteh ML, Sallah A, Jaiteh E, Allen A, Umoh D, Bass F, Dodd M, Howell C, Markaryan E, Hnatič R, Allen S. Rahden P, et al. BMJ Paediatr Open. 2025 Jan 23;9(1):e003133. doi: 10.1136/bmjpo-2024-003133. BMJ Paediatr Open. 2025. PMID: 39855680 Free PMC article. Clinical Trial.
METHODS: Randomised controlled feasibility trial with two phases: phase 1 (0-4 hours and double-blind) and phase 2 (up to 5 days and open-label). 50 children aged 6-59 months with acute diarrhoea presenting with no or some dehydration to the emergency paediatric unit and outpatie …
METHODS: Randomised controlled feasibility trial with two phases: phase 1 (0-4 hours and double-blind) and phase 2 (up to 5 days and open-la …