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Cardiopulmonary Profiling of Athletes with Post-Exertional Malaise after COVID-19 Infection-A Single-Center Experience.
Wernhart S, Weihe E, Totzeck M, Balcer B, Rassaf T, Luedike P. Wernhart S, et al. J Clin Med. 2023 Jun 28;12(13):4348. doi: 10.3390/jcm12134348. J Clin Med. 2023. PMID: 37445382 Free PMC article.
(1) Background: Cardiopulmonary exercise testing (CPET) has been suggested by the European Society of Cardiology (ESC) for assessing the exercise limitations of apparently healthy individuals, but data on elite athletes regarding this test are scarce. (2) Met …
(1) Background: Cardiopulmonary exercise testing (CPET) has been suggested by the European Society of Cardiology (ESC) for ass …
Predicting post-exertional malaise in Gulf War Illness based on acute exercise responses.
Boruch AE, Lindheimer JB, Klein-Adams JC, Stegner AJ, Wylie GR, Ninneman JV, Alexander T, Gretzon NP, Samy B, Van Riper SM, Falvo MJ, Cook DB. Boruch AE, et al. Life Sci. 2021 Sep 1;280:119701. doi: 10.1016/j.lfs.2021.119701. Epub 2021 Jun 10. Life Sci. 2021. PMID: 34119538 Free PMC article.
AIMS: Post-exertional malaise (PEM) is poorly understood in Gulf War Illness (GWI). Exercise challenges have emerged as stimuli to study PEM; however, little attention has been paid to unique cardiorespiratory and perceptual responses during exercis …
AIMS: Post-exertional malaise (PEM) is poorly understood in Gulf War Illness (GWI). Exercise challenges have eme …
Two-day cardiopulmonary exercise testing in long COVID post-exertional malaise diagnosis.
Gattoni C, Abbasi A, Ferguson C, Lanks CW, Decato TW, Rossiter HB, Casaburi R, Stringer WW. Gattoni C, et al. Respir Physiol Neurobiol. 2025 Jan;331:104362. doi: 10.1016/j.resp.2024.104362. Epub 2024 Oct 28. Respir Physiol Neurobiol. 2025. PMID: 39490617 Free article.
BACKGROUND: Long COVID patients present with a myriad of symptoms that can include fatigue, exercise intolerance and post exertional malaise (PEM). Long COVID has been compared to other post viral syndromes, including myalgic encephalomyelitis/chronic …
BACKGROUND: Long COVID patients present with a myriad of symptoms that can include fatigue, exercise intolerance and post e …
Post-exertional malaise in daily life and experimental exercise models in patients with myalgic encephalomyelitis/chronic fatigue syndrome.
Vøllestad NK, Mengshoel AM. Vøllestad NK, et al. Front Physiol. 2023 Dec 4;14:1257557. doi: 10.3389/fphys.2023.1257557. eCollection 2023. Front Physiol. 2023. PMID: 38111900 Free PMC article.
Post-exertional malaise (PEM) is commonly recognized as a hallmark of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and is often used as one of several criteria for diagnosing ME/CFS. ...There are indications of altered muscular metabolism and a …
Post-exertional malaise (PEM) is commonly recognized as a hallmark of myalgic encephalomyelitis/chronic fatigue syndrom …
Precision Medicine Study of Post-Exertional Malaise Epigenetic Changes in Myalgic Encephalomyelitis/Chronic Fatigue Patients During Exercise.
Sharma S, Hodges LD, Peppercorn K, Davis J, Edgar CD, Rodger EJ, Chatterjee A, Tate WP. Sharma S, et al. Int J Mol Sci. 2025 Sep 3;26(17):8563. doi: 10.3390/ijms26178563. Int J Mol Sci. 2025. PMID: 40943482 Free PMC article.
Post-exertional malaise (PEM) is a defining symptom of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), yet its molecular underpinnings remain elusive. This study investigated the temporal-longitudinal DNA methylation changes associated with PEM u …
Post-exertional malaise (PEM) is a defining symptom of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), yet …
Post-exertional malaise in Long COVID: subjective reporting versus objective assessment.
Stussman B, Camarillo N, McCrossin G, Stockman M, Norato G, Vetter CS, Ferrufino A, Adedamola A, Grayson N, Nath A, Chan L, Walitt B, Chin LMK. Stussman B, et al. Front Neurol. 2025 Apr 23;16:1534352. doi: 10.3389/fneur.2025.1534352. eCollection 2025. Front Neurol. 2025. PMID: 40337174 Free PMC article.
BACKGROUND: Post-exertional malaise (PEM) is a central feature of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and has emerged as a prominent feature of Long COVID. ...All cohorts completed questionnaires related to physical function, fatigue, …
BACKGROUND: Post-exertional malaise (PEM) is a central feature of myalgic encephalomyelitis/chronic fatigue syndrome (M …
Exercise-induced changes in gene expression do not mediate post exertional malaise in Gulf War illness.
Boruch AE, Lindheimer JB, Ninneman JV, Wylie GR, Alexander T, Klein-Adams JC, Stegner AJ, Gretzon NP, Samy B, Falvo MJ, Cook DB. Boruch AE, et al. Brain Behav Immun Health. 2023 Mar 11;29:100612. doi: 10.1016/j.bbih.2023.100612. eCollection 2023 May. Brain Behav Immun Health. 2023. PMID: 36950022 Free PMC article.
BACKGROUND: Post-exertional malaise (PEM) is considered a characteristic feature of chronic multi-symptom illnesses (CMI) like Gulf War illness (GWI); however, its pathophysiology remains understudied. ...Relative quantification of gene expression, symptom me …
BACKGROUND: Post-exertional malaise (PEM) is considered a characteristic feature of chronic multi-symptom illnesses (CM …
Characterization of Post-exertional Malaise in Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.
Stussman B, Williams A, Snow J, Gavin A, Scott R, Nath A, Walitt B. Stussman B, et al. Front Neurol. 2020 Sep 18;11:1025. doi: 10.3389/fneur.2020.01025. eCollection 2020. Front Neurol. 2020. PMID: 33071931 Free PMC article.
Methods: Nine focus groups totaling 43 patients who reported being diagnosed with myalgic encephalomyelitis/chronic fatigue syndrome were held between November 2016 and August 2019. Focus groups queried post-exertional malaise in daily life and participants' …
Methods: Nine focus groups totaling 43 patients who reported being diagnosed with myalgic encephalomyelitis/chronic fatigue syndrome were he …
Repeated Cardiopulmonary Exercise Testing of ME/CFS Patients.
Hodges L. Hodges L. Methods Mol Biol. 2025;2920:163-172. doi: 10.1007/978-1-0716-4498-0_10. Methods Mol Biol. 2025. PMID: 40372683
Post-exertional malaise is a cardinal symptom present in 95% of individuals with myalgic encephalomyelitis (ME/CFS). ...In this chapter, I describe the process and methods of repeated cardiopulmonary exercise testing, used to assess exercise …
Post-exertional malaise is a cardinal symptom present in 95% of individuals with myalgic encephalomyelitis (ME/CFS). .. …
Two symptoms can accurately identify post-exertional malaise in myalgic encephalomyelitis/chronic fatigue syndrome.
Davenport TE, Chu L, Stevens SR, Stevens J, Snell CR, Van Ness JM. Davenport TE, et al. Work. 2023;74(4):1199-1213. doi: 10.3233/WOR-220554. Work. 2023. PMID: 36938769
BACKGROUND: Post-exertional malaise (PEM) is the hallmark symptom of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) yet its diverse manifestations make it difficult to recognize. ...METHOD: 49 ME/CFS and 10 healthy, sedentary subjects recruited f …
BACKGROUND: Post-exertional malaise (PEM) is the hallmark symptom of myalgic encephalomyelitis/chronic fatigue syndrome …
41 results