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Year Number of Results
1979 1
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30 results

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Page 1
Optimizing animal models of autoimmune encephalitis using active immunization.
Linnoila J, Jalali Motlagh N, Jachimiec G, Lin CJ, Küllenberg E, Wojtkiewicz G, Tanzi R, Chen JW. Linnoila J, et al. Front Immunol. 2023 Jul 12;14:1177672. doi: 10.3389/fimmu.2023.1177672. eCollection 2023. Front Immunol. 2023. PMID: 37520559 Free PMC article.
N-methyl-D-aspartic acid receptor (NMDAR) encephalitis (NMDARE), characterized by serum and/or spinal fluid NMDAR antibodies, is the most common form of autoimmune encephalitis (AE). ...RESULTS: All immunized mice produced serum and CSF NMDAR antibodies, which peake …
N-methyl-D-aspartic acid receptor (NMDAR) encephalitis (NMDARE), characterized by serum and/or spinal fluid NMDAR antibodies, is the …
Immunogenic self-DNA drives neuropsychiatric systemic lupus erythematosus in conventional genetic background mice.
Xu F, Wen Z, Xiong S. Xu F, et al. Autoimmunity. 2025 Dec;58(1):2561610. doi: 10.1080/08916934.2025.2561610. Epub 2025 Sep 30. Autoimmunity. 2025. PMID: 41029970 Free article.
Self-DNA immunized mice developed progressive cognitive impairments, exhibiting spatial and working memory deficits from week 8 post-immunization, which worsened by week 12, alongside the emergence of anxiety-like and depression-like behaviors. ...Of note, blood-bra …
Self-DNA immunized mice developed progressive cognitive impairments, exhibiting spatial and working memory deficits from week 8 post- …
Anti-CRMP2 antibody induces anxiety-like behavior and increases pyramidal neuron excitability in mice.
Pan Y, Jiang Y, Wang D, Guo Z, He F, Chen Z, Dai C, Yuan Z, Chen R, Xu K, Hu Y. Pan Y, et al. Biochim Biophys Acta Mol Basis Dis. 2024 Oct;1870(7):167338. doi: 10.1016/j.bbadis.2024.167338. Epub 2024 Jul 8. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38986818 Free article.
BACKGROUND: We have previously identified auto-antibody (Ab) to collapsin response mediator protein 2 (CRMP2) in patients with encephalitis. The present study aims to evaluate the pathogenic effects of anti-CRMP2 Ab. ...RESULTS: The mice exhibited signs of impaired motor c …
BACKGROUND: We have previously identified auto-antibody (Ab) to collapsin response mediator protein 2 (CRMP2) in patients with encephalit …
Tinospora cordifolia Miers enhances the immune response in mice immunized with JEV-vaccine: A network pharmacology and experimental approach.
Tiwari P, Ali SA, Puri B, Kumar A, Datusalia AK. Tiwari P, et al. Phytomedicine. 2023 Oct;119:154976. doi: 10.1016/j.phymed.2023.154976. Epub 2023 Jul 19. Phytomedicine. 2023. PMID: 37573808
The surface expression of immune-cell markers (CD3(+), CD4(+), CD19(+), CD11c(+), CD40(+)) were evaluated on day 0 (pre-immunization), day 14 and 28 post-immunization. Additionally, inflammatory cytokines (IFN-gamma(+)/IL-17A(+)) were evaluated post-14 and 28 days o …
The surface expression of immune-cell markers (CD3(+), CD4(+), CD19(+), CD11c(+), CD40(+)) were evaluated on day 0 (pre-immunization), day 1 …
The suitability of yellow fever and Japanese encephalitis vaccines for immunization against West Nile virus.
Yamshchikov G, Borisevich V, Kwok CW, Nistler R, Kohlmeier J, Seregin A, Chaporgina E, Benedict S, Yamshchikov V. Yamshchikov G, et al. Vaccine. 2005 Sep 15;23(39):4785-92. doi: 10.1016/j.vaccine.2005.04.036. Vaccine. 2005. PMID: 15939510
All donors developed high levels of yellow fever virus (YFV) and Japanese encephalitis virus (JEV) neutralizing antibodies with titers 1:50 to 1:1600 and 1:20 to 1:640, respectively, and WNV neutralizing antibodies with titers 1:10 to 1:80. ...Cross-reactive anti-WNV respo …
All donors developed high levels of yellow fever virus (YFV) and Japanese encephalitis virus (JEV) neutralizing antibodies with titer …
Astroglial connexin 43 is a novel therapeutic target for chronic multiple sclerosis model.
Takase EO, Yamasaki R, Nagata S, Watanabe M, Masaki K, Yamaguchi H, Kira JI, Takeuchi H, Isobe N. Takase EO, et al. Sci Rep. 2024 May 13;14(1):10877. doi: 10.1038/s41598-024-61508-2. Sci Rep. 2024. PMID: 38740862 Free PMC article.
In chronic stages of multiple sclerosis (MS) and its animal model, experimental autoimmune encephalitis (EAE), connexin (Cx)43 gap junction channel proteins are overexpressed because of astrogliosis. ...C57BL6 mice with chronic EAE initiated by MOG(35-55) received INI-0602 …
In chronic stages of multiple sclerosis (MS) and its animal model, experimental autoimmune encephalitis (EAE), connexin (Cx)43 gap ju …
Post-vaccination encephalomyelitis: literature review and illustrative case.
Huynh W, Cordato DJ, Kehdi E, Masters LT, Dedousis C. Huynh W, et al. J Clin Neurosci. 2008 Dec;15(12):1315-22. doi: 10.1016/j.jocn.2008.05.002. Epub 2008 Oct 30. J Clin Neurosci. 2008. PMID: 18976924 Free PMC article. Review.
ADEM forms one of several categories of primary inflammatory demyelinating disorders of the central nervous system including multiple sclerosis, optic neuropathy, acute transverse myelitis, and neuromyelitis optica (Devic's disease). Post-infectious and post-immunisatio …
ADEM forms one of several categories of primary inflammatory demyelinating disorders of the central nervous system including multiple sclero …
Vaccine-associated respiratory pathology correlates with viral clearance and protective immunity after immunization with self-amplifying RNA expressing the spike (S) protein of SARS-CoV-2 in mouse models.
Kachko A, Selvaraj P, Liu S, Kim J, Rotstein D, Stauft CB, Chabot S, Rajasagi N, Zhao Y, Wang T, Major M. Kachko A, et al. Vaccine. 2024 Jan 25;42(3):608-619. doi: 10.1016/j.vaccine.2023.12.052. Epub 2023 Dec 23. Vaccine. 2024. PMID: 38142216 Free article.
In this study, we evaluated the immunogenicity and protective immunity of in vitro transcribed Venezuelan equine encephalitis virus (VEEV TC-83 strain) self-amplifying RNA (saRNA) encoding the SARS-CoV-2 spike (S) protein in wild type (S-WT) and stabilized pre-fusion confo …
In this study, we evaluated the immunogenicity and protective immunity of in vitro transcribed Venezuelan equine encephalitis virus ( …
Post-marketing surveillance of immediate allergic reactions: polygeline-based versus polygeline-free pediatric TBE vaccine.
Zent O, Hennig R. Zent O, et al. Vaccine. 2004 Dec 16;23(5):579-84. doi: 10.1016/j.vaccine.2004.07.016. Vaccine. 2004. PMID: 15542177
Scattered cases of immediate allergic reactions occurred in the nineties after widespread use of the original (polygeline-based) pediatric tick-borne encephalitis (TBE) vaccine and were reported to Pharmacovigilance, Chiron Vaccines. Although, still indicating a very rare …
Scattered cases of immediate allergic reactions occurred in the nineties after widespread use of the original (polygeline-based) pediatric t …
30 results