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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1966 1
1967 2
1968 2
1970 1
1971 6
1972 5
1973 2
1974 4
1975 22
1976 20
1977 10
1978 30
1979 24
1980 22
1981 19
1982 17
1983 21
1984 27
1985 30
1986 35
1987 50
1988 39
1989 42
1990 51
1991 49
1992 57
1993 51
1994 64
1995 64
1996 59
1997 68
1998 67
1999 72
2000 53
2001 58
2002 79
2003 67
2004 69
2005 44
2006 62
2007 53
2008 37
2009 43
2010 49
2011 50
2012 53
2013 55
2014 43
2015 38
2016 30
2017 30
2018 39
2019 33
2020 36
2021 30
2022 25
2023 24
2024 20
2025 17

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2,066 results

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Page 1
High endothelial venules in cancer: Regulation, function, and therapeutic implication.
Vella G, Hua Y, Bergers G. Vella G, et al. Cancer Cell. 2023 Mar 13;41(3):527-545. doi: 10.1016/j.ccell.2023.02.002. Epub 2023 Feb 23. Cancer Cell. 2023. PMID: 36827979 Free article. Review.
The lack of sufficient intratumoral CD8(+) T lymphocytes is a significant obstacle to effective immunotherapy in cancer. High endothelial venules (HEVs) are organ-specific and specialized postcapillary venules uniquely poised to facilitate the transmigration …
The lack of sufficient intratumoral CD8(+) T lymphocytes is a significant obstacle to effective immunotherapy in cancer. High endothelial …
Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy.
Asrir A, Tardiveau C, Coudert J, Laffont R, Blanchard L, Bellard E, Veerman K, Bettini S, Lafouresse F, Vina E, Tarroux D, Roy S, Girault I, Molinaro I, Martins F, Scoazec JY, Ortega N, Robert C, Girard JP. Asrir A, et al. Cancer Cell. 2022 Mar 14;40(3):318-334.e9. doi: 10.1016/j.ccell.2022.01.002. Epub 2022 Feb 3. Cancer Cell. 2022. PMID: 35120598 Free article.
We show in murine models that tumor-associated high endothelial venules (TA-HEVs) are major sites of lymphocyte entry into tumors at baseline and upon treatment with anti-PD-1/anti-CTLA-4 immune checkpoint blockade (ICB). TA-HEV endothelial cells (TA-HECs) derive from post …
We show in murine models that tumor-associated high endothelial venules (TA-HEVs) are major sites of lymphocyte entry into tumors at …
Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop.
Hua Y, Vella G, Rambow F, Allen E, Antoranz Martinez A, Duhamel M, Takeda A, Jalkanen S, Junius S, Smeets A, Nittner D, Dimmeler S, Hehlgans T, Liston A, Bosisio FM, Floris G, Laoui D, Hollmén M, Lambrechts D, Merchiers P, Marine JC, Schlenner S, Bergers G. Hua Y, et al. Cancer Cell. 2022 Dec 12;40(12):1600-1618.e10. doi: 10.1016/j.ccell.2022.11.002. Epub 2022 Nov 23. Cancer Cell. 2022. PMID: 36423635 Free PMC article.
By employing single-cell transcriptomics, endothelial fate mapping, and functional multiplex immune profiling, we demonstrate that antiangiogenic immune-modulating therapies evoke transdifferentiation of postcapillary venules into inflamed high-endothelial venule …
By employing single-cell transcriptomics, endothelial fate mapping, and functional multiplex immune profiling, we demonstrate that antiangio …
Single-cell transcriptome profiling reveals vascular endothelial cell heterogeneity in human skin.
Li Q, Zhu Z, Wang L, Lin Y, Fang H, Lei J, Cao T, Wang G, Dang E. Li Q, et al. Theranostics. 2021 Apr 19;11(13):6461-6476. doi: 10.7150/thno.54917. eCollection 2021. Theranostics. 2021. PMID: 33995668 Free PMC article.
Metabolic transcriptome analysis revealed a preference for oxidative phosphorylation in arteriole ECs when compared to capillary and venule ECs. Capillary ECs abundantly expressed HLA-II molecules, suggesting its immune-surveillance role. Post-capillary venule ECs, …
Metabolic transcriptome analysis revealed a preference for oxidative phosphorylation in arteriole ECs when compared to capillary and venu …
[Angioedema].
Holguín-Gómez L, Vásquez-Ochoa LA, Cardona R. Holguín-Gómez L, et al. Rev Alerg Mex. 2016 Oct-Dec;63(4):373-384. doi: 10.29262/ram.v63i4.220. Rev Alerg Mex. 2016. PMID: 27795218 Spanish.
It occurs due to increased permeability of the mucosal and submucosal capillaries and postcapillary venules, with resulting plasma extravasation. There are different types of angioedema: histaminergic (which may be mediated by immunoglobulin E), hereditary, from acq …
It occurs due to increased permeability of the mucosal and submucosal capillaries and postcapillary venules, with resulting pl …
Mediators of Capillary-to-Venule Conversion in the Chronic Inflammatory Skin Disease Psoriasis.
He Y, Kim J, Tacconi C, Moody J, Dieterich LC, Anzengruber F, Maul JT, Gousopoulos E, Restivo G, Levesque MP, Lindenblatt N, Shin JW, Hon CC, Detmar M. He Y, et al. J Invest Dermatol. 2022 Dec;142(12):3313-3326.e13. doi: 10.1016/j.jid.2022.05.1089. Epub 2022 Jun 28. J Invest Dermatol. 2022. PMID: 35777499 Free article.
Blood capillaries, in particular, showed upregulation of the melanoma cell adhesion molecule as well as its binding partners and adopted postcapillary venule-like characteristics during chronic inflammation that are more permissive to leukocyte transmigration. ...
Blood capillaries, in particular, showed upregulation of the melanoma cell adhesion molecule as well as its binding partners and adopted …
A composite model of the human postcapillary venule for investigation of microvascular leukocyte recruitment.
Lauridsen HM, Pober JS, Gonzalez AL. Lauridsen HM, et al. FASEB J. 2014 Mar;28(3):1166-80. doi: 10.1096/fj.13-240986. Epub 2013 Dec 2. FASEB J. 2014. PMID: 24297702 Free PMC article.
Neutrophil extravasation occurs across postcapillary venules, structures composed of endothelial cells (ECs), pericytes (PCs), and basement membrane (BM). We constructed composite models of the human postcapillary venule, combining ECs with PCs or PC-d …
Neutrophil extravasation occurs across postcapillary venules, structures composed of endothelial cells (ECs), pericytes (PCs), …
Cutaneous small-vessel vasculitis.
Lotti T, Ghersetich I, Comacchi C, Jorizzo JL. Lotti T, et al. J Am Acad Dermatol. 1998 Nov;39(5 Pt 1):667-87; quiz 688-90. doi: 10.1016/s0190-9622(98)70039-8. J Am Acad Dermatol. 1998. PMID: 9810883 Review.
Cutaneous small-vessel vasculitis (CSVV) refers to a group of disorders usually characterized by palpable purpura; it is caused by leukocytoclastic vasculitis of postcapillary venules. CSVV can be idiopathic or can be associated with a drug, infection, or underlying …
Cutaneous small-vessel vasculitis (CSVV) refers to a group of disorders usually characterized by palpable purpura; it is caused by leukocyto …
Role of high endothelial postcapillary venules and selected adhesion molecules in periodontal diseases: a review.
Kasprzak A, Surdacka A, Tomczak M, Konkol M. Kasprzak A, et al. J Periodontal Res. 2013 Feb;48(1):1-21. doi: 10.1111/j.1600-0765.2012.01492.x. Epub 2012 May 14. J Periodontal Res. 2013. PMID: 22582923 Review.
Periodontitis is accompanied by the proliferation of small blood vessels in the gingival lamina propria. Specialized postcapillary venules, termed periodontal high endothelial-like venules, are also present, and demonstrate morphological and functional traits …
Periodontitis is accompanied by the proliferation of small blood vessels in the gingival lamina propria. Specialized postcapillary …
Postcapillary venule endothelial cells in kidney express a multispecific chemokine receptor that is structurally and functionally identical to the erythroid isoform, which is the Duffy blood group antigen.
Hadley TJ, Lu ZH, Wasniowska K, Martin AW, Peiper SC, Hesselgesser J, Horuk R. Hadley TJ, et al. J Clin Invest. 1994 Sep;94(3):985-91. doi: 10.1172/JCI117465. J Clin Invest. 1994. PMID: 8083383 Free PMC article.
Immunocytochemical staining of kidney with Fy6 localized expression to endothelial cells present in postcapillary venules. These studies implicate the Duffy antigen/chemokine receptor in the complex interactions between postcapillary endothelial cells and gra …
Immunocytochemical staining of kidney with Fy6 localized expression to endothelial cells present in postcapillary venules. The …
2,066 results