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Year Number of Results
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949 results

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Page 1
Jinlida for Diabetes Prevention in Impaired Glucose Tolerance and Multiple Metabolic Abnormalities: The FOCUS Randomized Clinical Trial.
Ji H, Zhao X, Chen X, Fang H, Gao H, Wei G, Zhang M, Kuang H, Yang B, Cai X, Su Y, Piao C, Zhao S, Li L, Sun W, Xu T, Xu Q, Fan Y, Ye J, Yao C, Shang M, Song G, Chen L, Zheng Q, Xiao X, Yan L, Lian F, Tong X, Jia Z; FOCUS Trial Committees and Investigators. Ji H, et al. JAMA Intern Med. 2024 Jul 1;184(7):727-735. doi: 10.1001/jamainternmed.2024.1190. JAMA Intern Med. 2024. PMID: 38829648 Free PMC article. Clinical Trial.
IMPORTANCE: Previous studies have shown that Jinlida (JLD) granules, an approved treatment for type 2 diabetes in China, can reduce blood glucose level, reduce glycated hemoglobin (HbA1c), and improve insulin resistance in people with type 2 diabetes. ...MAIN …
IMPORTANCE: Previous studies have shown that Jinlida (JLD) granules, an approved treatment for type 2 diabetes in China, can reduce blood …
Hepatic insulin resistance and muscle insulin resistance are characterized by distinct postprandial plasma metabolite profiles: a cross-sectional study.
Gijbels A, Erdős B, Trouwborst I, Jardon KM, Adriaens ME, Goossens GH, Blaak EE, Feskens EJM, Afman LA. Gijbels A, et al. Cardiovasc Diabetol. 2024 Mar 16;23(1):97. doi: 10.1186/s12933-024-02188-0. Cardiovasc Diabetol. 2024. PMID: 38493102 Free PMC article.
BACKGROUND: Tissue-specific insulin resistance (IR) predominantly in muscle (muscle IR) or liver (liver IR) has previously been linked to distinct fasting metabolite profiles, but postprandial metabolite profiles have not been investigated in tissue-specific …
BACKGROUND: Tissue-specific insulin resistance (IR) predominantly in muscle (muscle IR) or liver (liver IR) has previously bee …
Postprandial fatty acid-binding protein 4 is associated with muscle insulin resistance.
Okura T, Ito Y, Anno M, Endo S, Kitao S, Nakamura R, Matsumoto K, Shoji K, Okura H, Matsuzawa K, Izawa S, Ichihara Y, Ueta E, Kato M, Imamura T, Taniguchi SI, Yamamoto K. Okura T, et al. Diabetologia. 2024 Oct;67(10):2304-2315. doi: 10.1007/s00125-024-06222-4. Epub 2024 Jul 26. Diabetologia. 2024. PMID: 39060707
AIMS/HYPOTHESIS: Fatty acid-binding protein 4 (FABP4) has been reported to act as a hepatic insulin resistance factor. We previously reported that fasting FABP4 was correlated with insulin resistance measurements derived from the glucose clamp, …
AIMS/HYPOTHESIS: Fatty acid-binding protein 4 (FABP4) has been reported to act as a hepatic insulin resistance factor. We prev …
Association of postprandial triglyceride responses with insulin resistance among rotational night shift healthcare workers.
Kiranmala K, Aslam M, Mishra BK, Jhamb R, Madhu SV. Kiranmala K, et al. Exp Physiol. 2019 Jun;104(6):819-825. doi: 10.1113/EP087514. Epub 2019 Apr 2. Exp Physiol. 2019. PMID: 30941848 Free article.
Does long-term rotational night shift work among healthcare workers alter postprandial triglyceride metabolism, and are the postprandial triglyceride responses associated with insulin resistance? ...ABSTRACT: Studies on the postprandial perio
Does long-term rotational night shift work among healthcare workers alter postprandial triglyceride metabolism, and are the postpr
On the paradox insulin resistance/insulin hypersensitivity and obesity: two tales of the same history.
Guiducci L, Iervasi G, Quinones-Galvan A. Guiducci L, et al. Expert Rev Cardiovasc Ther. 2014 Jun;12(6):637-42. doi: 10.1586/14779072.2014.910115. Expert Rev Cardiovasc Ther. 2014. PMID: 24846675
Insulin resistance (IR) associated with obesity represents a well-known risk factor for chronic disease. ...By performing an OGTT in obese or obese-prone individuals we observed that tardive post-prandial hypoglycemia (3h from glucose load) is not a ra
Insulin resistance (IR) associated with obesity represents a well-known risk factor for chronic disease. ...By performing an
Postprandial reactive hypoglycemia.
Brun JF, Fedou C, Mercier J. Brun JF, et al. Diabetes Metab. 2000 Nov;26(5):337-51. Diabetes Metab. 2000. PMID: 11119013 Review.
Neither the oral glucose tolerance test (OGTT) nor mixed meals are suitable for this diagnosis, due to respectively false positive and false negative results. ...PRH could result from (a) an exaggerated insulin response, either related to ins
Neither the oral glucose tolerance test (OGTT) nor mixed meals are suitable for this diagnosis, due to respectiv …
Both macronutrient food composition and fasting insulin resistance affect postprandial glycemic responses in senior subjects.
Galarregui C , Navas-Carretero S , González-Navarro CJ , Martínez JA , Zulet MA , Abete I . Galarregui C , et al. Food Funct. 2021 Jul 21;12(14):6540-6548. doi: 10.1039/d1fo00731a. Epub 2021 Jun 7. Food Funct. 2021. PMID: 34096954 Clinical Trial.
INTRODUCTION: Postprandial hyperglycemia is a risk factor for type 2 diabetes. Insulin resistance (IR) might affect metabolic responses in non-fasting states. ...METHODS: In a randomized, controlled crossover design, thirty-four adults consumed a test
INTRODUCTION: Postprandial hyperglycemia is a risk factor for type 2 diabetes. Insulin resistance (IR) might affect met …
Sucralose consumption modifies glucose homeostasis, gut microbiota, Curli protein, and related metabolites in healthy individuals: A randomized placebo-controlled, triple-blind trial.
Romo-Romo A, Sánchez-Tapia M, López-Carrasco MG, Guillén-Pineda LE, Brito-Córdova GX, Martagón AJ, Granados-Portillo O, Walther G, Gómez-Pérez FJ, Aguilar-Salinas CA, Tovar AR, Torres N, Almeda-Valdes P. Romo-Romo A, et al. Clin Nutr ESPEN. 2025 Oct;69:733-744. doi: 10.1016/j.clnesp.2025.08.029. Epub 2025 Sep 2. Clin Nutr ESPEN. 2025. PMID: 40907790 Clinical Trial.
BACKGROUND & AIMS: Sucralose consumption has been associated with a reduction in insulin sensitivity, potentially through changes in gut microbiota, induction of low-grade inflammation and other pathophysiologic mechanisms, thus the aim of this study was to evaluate th …
BACKGROUND & AIMS: Sucralose consumption has been associated with a reduction in insulin sensitivity, potentially through changes …
Effects of Obesity and Hyperglycemia on Postprandial Insulin-Mediated and Non-Insulin-Mediated Glucose Disposal.
Mittendorfer B, Patterson BW, Smith GI, Yoshino M, Klein S. Mittendorfer B, et al. Diabetes Care. 2025 Jan 1;48(1):84-92. doi: 10.2337/dc24-1280. Diabetes Care. 2025. PMID: 39499792 Free PMC article.
RESEARCH DESIGN AND METHODS: We developed and validated a new glucose tracer model in conjunction with an oral glucose tolerance test to determine IMGD, NIMGD, and TGD (sum of IMGD and NIMGD) after glucose ingestion in four groups of people: 1) …
RESEARCH DESIGN AND METHODS: We developed and validated a new glucose tracer model in conjunction with an oral glucose tole
Glucose allostasis.
Stumvoll M, Tataranni PA, Stefan N, Vozarova B, Bogardus C. Stumvoll M, et al. Diabetes. 2003 Apr;52(4):903-9. doi: 10.2337/diabetes.52.4.903. Diabetes. 2003. PMID: 12663459
In many organisms, normoglycemia is achieved by a tight coupling of nutrient-stimulated insulin secretion in the pancreatic beta-cell (acute insulin response [AIR]) and the metabolic action of insulin to stimulate glucose disposal (insulin actio …
In many organisms, normoglycemia is achieved by a tight coupling of nutrient-stimulated insulin secretion in the pancreatic beta-cell …
949 results