Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1956 2
1964 1
1968 2
1972 1
1974 7
1975 6
1976 11
1977 9
1978 13
1979 17
1980 11
1981 16
1982 25
1983 27
1984 23
1985 36
1986 34
1987 24
1988 26
1989 14
1990 19
1991 22
1992 31
1993 26
1994 17
1995 32
1996 41
1997 45
1998 65
1999 86
2000 98
2001 98
2002 103
2003 133
2004 132
2005 124
2006 113
2007 129
2008 142
2009 131
2010 132
2011 112
2012 118
2013 148
2014 148
2015 128
2016 122
2017 80
2018 81
2019 78
2020 78
2021 69
2022 60
2023 40
2024 67
2025 55
2026 28

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

3,146 results

Results by year

Filters applied: . Clear all
Page 1
Reconstituted Postsynaptic Density as a Molecular Platform for Understanding Synapse Formation and Plasticity.
Zeng M, Chen X, Guan D, Xu J, Wu H, Tong P, Zhang M. Zeng M, et al. Cell. 2018 Aug 23;174(5):1172-1187.e16. doi: 10.1016/j.cell.2018.06.047. Epub 2018 Aug 14. Cell. 2018. PMID: 30078712 Free article.
Here, we used a biochemical reconstitution approach to show that, both in solution and on supported membrane bilayers, multivalent interaction networks formed by major excitatory postsynaptic density (PSD) scaffold proteins led to formation of PSD-like assemb …
Here, we used a biochemical reconstitution approach to show that, both in solution and on supported membrane bilayers, multivalent in …
Postsynaptic density-membrane associated guanylate kinase proteins (PSD-MAGUKs) and their role in CNS disorders.
Gardoni F, Marcello E, Di Luca M. Gardoni F, et al. Neuroscience. 2009 Jan 12;158(1):324-33. doi: 10.1016/j.neuroscience.2008.07.068. Epub 2008 Aug 13. Neuroscience. 2009. PMID: 18773944 Review.
Membrane associated guanylate kinase proteins (MAGUKs) play a key role in the regulation of the intracellular trafficking and synaptic localization of ionotropic glutamate receptors. In particular, the postsynaptic density-95-like subfamily of MAGUKs (PSD-MAG …
Membrane associated guanylate kinase proteins (MAGUKs) play a key role in the regulation of the intracellular trafficking and synapti …
The postsynaptic density.
Boeckers TM. Boeckers TM. Cell Tissue Res. 2006 Nov;326(2):409-22. doi: 10.1007/s00441-006-0274-5. Epub 2006 Jul 25. Cell Tissue Res. 2006. PMID: 16865346 Review.
Glutamatergic synapses in the central nervous system are characterized by an electron-dense web underneath the postsynaptic membrane; this web is called the postsynaptic density (PSD). PSDs are composed of a dense network of several hundred proteins, c …
Glutamatergic synapses in the central nervous system are characterized by an electron-dense web underneath the postsynaptic membra …
Multiphase separation in postsynaptic density regulated by membrane geometry via interaction valency and volume.
Yamada R, Brandani GB, Takada S. Yamada R, et al. Elife. 2025 Sep 23;14:RP106602. doi: 10.7554/eLife.106602. Elife. 2025. PMID: 40985614 Free PMC article.
Recent studies reported a puzzling multiphase morphology in postsynaptic density components: AMPA receptor, NMDA receptor, PSD-95, and CaMKII. The multiphase morphology appears reversed when transitioning from the solution to the membrane. ...Then, we obtain …
Recent studies reported a puzzling multiphase morphology in postsynaptic density components: AMPA receptor, NMDA receptor, PSD …
Liquid-liquid phase separation in biology: mechanisms, physiological functions and human diseases.
Zhang H, Ji X, Li P, Liu C, Lou J, Wang Z, Wen W, Xiao Y, Zhang M, Zhu X. Zhang H, et al. Sci China Life Sci. 2020 Jul;63(7):953-985. doi: 10.1007/s11427-020-1702-x. Epub 2020 Apr 30. Sci China Life Sci. 2020. PMID: 32548680 Review.
The molecular mechanisms underlying the dynamics of membrane-bound organelles, such as their fusion and fission, vesicle-mediated trafficking and membrane contactmediated inter-organelle interactions, have been extensively characterized. ...Phase-separated condensat …
The molecular mechanisms underlying the dynamics of membrane-bound organelles, such as their fusion and fission, vesicle-mediated tra …
Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity.
Zeng M, Shang Y, Araki Y, Guo T, Huganir RL, Zhang M. Zeng M, et al. Cell. 2016 Aug 25;166(5):1163-1175.e12. doi: 10.1016/j.cell.2016.07.008. Cell. 2016. PMID: 27565345 Free PMC article.
Postsynaptic densities (PSDs) are membrane semi-enclosed, submicron protein-enriched cellular compartments beneath postsynaptic membranes, which constantly exchange their components with bulk aqueous cytoplasm in synaptic spines. ...
Postsynaptic densities (PSDs) are membrane semi-enclosed, submicron protein-enriched cellular compartments beneath postsyna …
Microneedle-mediated nose-to-brain drug delivery for improved Alzheimer's disease treatment.
Ruan S, Li J, Ruan H, Xia Q, Hou X, Wang Z, Guo T, Zhu C, Feng N, Zhang Y. Ruan S, et al. J Control Release. 2024 Feb;366:712-731. doi: 10.1016/j.jconrel.2024.01.013. Epub 2024 Jan 18. J Control Release. 2024. PMID: 38219911
The efficacy of huperzine A on scopolamine- and D-galactose & AlCl(3)-induced memory deficits in rats was significantly improved, as evidenced by inhibiting acetylcholinesterase activity, alleviating oxidative stress damage in the brain, and improving learning function, meanw …
The efficacy of huperzine A on scopolamine- and D-galactose & AlCl(3)-induced memory deficits in rats was significantly improved, as evi …
The postsynaptic density in excitatory synapses is composed of clustered, heterogeneous nanoblocks.
Sun R, Allen JP, Mao Z, Wilson L, Haider M, Alten B, Zhou Z, Wang X, Zhou Q. Sun R, et al. J Cell Biol. 2025 Jun 2;224(6):e202406133. doi: 10.1083/jcb.202406133. Epub 2025 Mar 27. J Cell Biol. 2025. PMID: 40145863 Free PMC article.
Here, we used cryo-electron tomography (cryo-ET) to directly visualize the three-dimensional architecture and supramolecular organization of postsynaptic components in both synaptosomes and synapses from cultured neurons. Cryo-ET revealed that postsynaptic densit …
Here, we used cryo-electron tomography (cryo-ET) to directly visualize the three-dimensional architecture and supramolecular organization of …
Postsynaptic Density Proteins and Their Role in the Trafficking of Group I Metabotropic Glutamate Receptors.
Aruna K, Pal S, Khanna A, Bhattacharyya S. Aruna K, et al. J Membr Biol. 2024 Dec;257(5-6):257-268. doi: 10.1007/s00232-024-00326-z. Epub 2024 Oct 6. J Membr Biol. 2024. PMID: 39369356 Review.
There is growing evidence implicating dysregulated glutamate receptor trafficking in the pathophysiology of several neuropsychiatric disorders. The postsynaptic density (PSD) region consists of many specialized proteins which are assembled beneath the postsynapti …
There is growing evidence implicating dysregulated glutamate receptor trafficking in the pathophysiology of several neuropsychiatric disorde …
Association of membrane rafts and postsynaptic density: proteomics, biochemical, and ultrastructural analyses.
Suzuki T, Zhang J, Miyazawa S, Liu Q, Farzan MR, Yao WD. Suzuki T, et al. J Neurochem. 2011 Oct;119(1):64-77. doi: 10.1111/j.1471-4159.2011.07404.x. Epub 2011 Aug 22. J Neurochem. 2011. PMID: 21797867 Free PMC article.
Neurochem. (2011) 119, 64-77. ABSTRACT: Postsynaptic membrane rafts are believed to play important roles in synaptic signaling, plasticity, and maintenance. ...Further, how they interact with the well-established signaling specialization, the postsynaptic …
Neurochem. (2011) 119, 64-77. ABSTRACT: Postsynaptic membrane rafts are believed to play important roles in synaptic signaling …
3,146 results