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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 1
1988 2
1989 2
1990 2
1993 4
1994 2
1995 3
1996 3
1997 4
1998 6
1999 2
2000 16
2001 4
2002 2
2003 3
2004 8
2005 12
2006 13
2007 16
2008 32
2009 47
2010 65
2011 67
2012 105
2013 140
2014 182
2015 215
2016 251
2017 297
2018 336
2019 417
2020 528
2021 691
2022 753
2023 822
2024 1127
2025 1911
2026 1004

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8,226 results

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Page 1
Pharmacogenomics: Driving Personalized Medicine.
Sadee W, Wang D, Hartmann K, Toland AE. Sadee W, et al. Pharmacol Rev. 2023 Jul;75(4):789-814. doi: 10.1124/pharmrev.122.000810. Epub 2023 Mar 16. Pharmacol Rev. 2023. PMID: 36927888 Free PMC article. Review.
Personalized medicine tailors therapies, disease prevention, and health maintenance to the individual, with pharmacogenomics serving as a key tool to improve outcomes and prevent adverse effects. ...SIGNIFICANCE STATEMENT: Personalized medici …
Personalized medicine tailors therapies, disease prevention, and health maintenance to the individual, with pharmacogen …
Predictive, preventive, and personalized medicine in breast cancer: targeting the PI3K pathway.
Tufail M, Hu JJ, Liang J, He CY, Wan WD, Huang YQ, Jiang CH, Wu H, Li N. Tufail M, et al. J Transl Med. 2024 Jan 3;22(1):15. doi: 10.1186/s12967-023-04841-w. J Transl Med. 2024. PMID: 38172946 Free PMC article. Review.
This review article explores the implications of the PI3K pathway in predictive, preventive, and personalized medicine for BC. It emphasizes the identification of predictive biomarkers, such as PIK3CA mutations, and the utility of molecular prof …
This review article explores the implications of the PI3K pathway in predictive, preventive, and personalized medici …
Dynamic Changes in Metabolic Syndrome Scores and New-Onset Stroke Risk in Middle-Aged and Older Adults: A Nationwide Prospective Cohort Study in China Aligned With Predictive, Preventive, and Personalized Medicine.
Li Q, Liu Y, Gao X, Fang Q, Zeng L, Xu Y, Huang J. Li Q, et al. J Am Heart Assoc. 2025 Nov 18;14(22):e041833. doi: 10.1161/JAHA.125.041833. Epub 2025 Nov 11. J Am Heart Assoc. 2025. PMID: 41220136 Free PMC article.
The gradient boosting machine model achieved superior predictive accuracy, reflected by an area under the curve of 0.76 (95% CI, 0.72-0.79). Shapley additive explanations identified age, MetS score, and body mass index as the most influential predictors. ...Moreover, the M …
The gradient boosting machine model achieved superior predictive accuracy, reflected by an area under the curve of 0.76 (95% CI, 0.72 …
Targeted Therapy and Personalized Medicine.
Saeed RF, Awan UA, Saeed S, Mumtaz S, Akhtar N, Aslam S. Saeed RF, et al. Cancer Treat Res. 2023;185:177-205. doi: 10.1007/978-3-031-27156-4_10. Cancer Treat Res. 2023. PMID: 37306910
Targeted therapy and personalized medicine are novel emerging disciplines of cancer research intended for treatment and prevention. ...Hence, in this chapter, we will discuss recent advancements, challenges, and opportunities in personalized medicin …
Targeted therapy and personalized medicine are novel emerging disciplines of cancer research intended for treatment and pre …
The personal and clinical utility of polygenic risk scores.
Torkamani A, Wineinger NE, Topol EJ. Torkamani A, et al. Nat Rev Genet. 2018 Sep;19(9):581-590. doi: 10.1038/s41576-018-0018-x. Nat Rev Genet. 2018. PMID: 29789686 Review.
Initial expectations for genome-wide association studies were high, as such studies promised to rapidly transform personalized medicine with individualized disease risk predictions, prevention strategies and treatments. ...As a result, the practice of …
Initial expectations for genome-wide association studies were high, as such studies promised to rapidly transform personalized med …
Predictive, Personalized, Preventive and Participatory (4P) Medicine Applied to Telemedicine and eHealth in the Literature.
Alonso SG, de la Torre Díez I, Zapiraín BG. Alonso SG, et al. J Med Syst. 2019 Apr 12;43(5):140. doi: 10.1007/s10916-019-1279-4. J Med Syst. 2019. PMID: 30976942 Review.
The main objective of this work is to provide a review of existing research work into predictive, personalized, preventive and participatory medicine in telemedicine and ehealth. ...A total of 184 publications about predictive, personalized …
The main objective of this work is to provide a review of existing research work into predictive, personalized, preventive …
Application of P4 (Predictive, Preventive, Personalized, Participatory) Approach to Occupational Medicine.
Boffetta P, Collatuzzo G. Boffetta P, et al. Med Lav. 2022 Feb 22;113(1):e2022009. doi: 10.23749/mdl.v113i1.12622. Med Lav. 2022. PMID: 35226650 Free PMC article. Review.
Additionally, the prevalence and outcome of different chronic diseases and cancers is burdened by social disparities. P4 [predictive, preventive, personalized, participatory] medicine is the conceptualization of a new health care model, based on multid …
Additionally, the prevalence and outcome of different chronic diseases and cancers is burdened by social disparities. P4 [predictive, …
Impact of predictive, preventive and precision medicine strategies in epilepsy.
Nabbout R, Kuchenbuch M. Nabbout R, et al. Nat Rev Neurol. 2020 Dec;16(12):674-688. doi: 10.1038/s41582-020-0409-4. Epub 2020 Oct 19. Nat Rev Neurol. 2020. PMID: 33077944 Review.
Thus, now is the time for a paradigm shift in epilepsy treatment from a reactive attitude, treating patients after the onset of epilepsy and the initiation of seizures, to a proactive attitude that is more broadly integrated into a 'P4 medicine' approach. This P4 approach, …
Thus, now is the time for a paradigm shift in epilepsy treatment from a reactive attitude, treating patients after the onset of epilepsy and …
Personalised medicine in asthma: from curative to preventive medicine.
Guilleminault L, Ouksel H, Belleguic C, Le Guen Y, Germaud P, Desfleurs E, Leroyer C, Magnan A. Guilleminault L, et al. Eur Respir Rev. 2017 Jan 3;26(143):160010. doi: 10.1183/16000617.0010-2016. Print 2017 Jan. Eur Respir Rev. 2017. PMID: 28049124 Free PMC article. Review.
This personalised approach to curative medicine should make way in the coming years for personalised preventive and predictive medicine, focused on subjects at risk who are not yet ill, with the aim of preventing asthma before it occurs. The con …
This personalised approach to curative medicine should make way in the coming years for personalised preventive and predict …
The predictive, preventive, and personalized medicine of multiple sclerosis: ferroptosis and circulating proteins.
Xiong Y, Yang D, Cai S. Xiong Y, et al. Neurol Res. 2026 Jun;48(6):723-731. doi: 10.1080/01616412.2025.2541908. Epub 2025 Aug 14. Neurol Res. 2026. PMID: 40813130 Free article.
OBJECTIVE: Based on the principles of Predictive, Preventive, and Personalized Medicine (PPPM), this study aimed to identify ferroptosis-related genes associated with multiple sclerosis (MS) and to explore the underlying mechanisms through genetic appr …
OBJECTIVE: Based on the principles of Predictive, Preventive, and Personalized Medicine (PPPM), this study aimed …
8,226 results