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Showing results for prenatal famine
Your search for prenantal famine retrieved no results
Persistent epigenetic differences associated with prenatal exposure to famine in humans.
Heijmans BT, Tobi EW, Stein AD, Putter H, Blauw GJ, Susser ES, Slagboom PE, Lumey LH. Heijmans BT, et al. Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17046-9. doi: 10.1073/pnas.0806560105. Epub 2008 Oct 27. Proc Natl Acad Sci U S A. 2008. PMID: 18955703 Free PMC article.
Although the mechanisms behind these relationships are unclear, an involvement of epigenetic dysregulation has been hypothesized. Here we show that individuals who were prenatally exposed to famine during the Dutch Hunger Winter in 1944-45 had, 6 decades later, less …
Although the mechanisms behind these relationships are unclear, an involvement of epigenetic dysregulation has been hypothesized. Here we sh …
Prenatal exposure to the Dutch famine and disease in later life: an overview.
Painter RC, Roseboom TJ, Bleker OP. Painter RC, et al. Reprod Toxicol. 2005 Sep-Oct;20(3):345-52. doi: 10.1016/j.reprotox.2005.04.005. Reprod Toxicol. 2005. PMID: 15893910 Review.
We found more coronary heart disease, raised lipids, altered clotting and more obesity after exposure to famine in early gestation compared to those not exposed to the famine. ...Future research should shed more light upon the underlying pathophysiology of the far-r …
We found more coronary heart disease, raised lipids, altered clotting and more obesity after exposure to famine in early gestation co …
DNA methylation signatures link prenatal famine exposure to growth and metabolism.
Tobi EW, Goeman JJ, Monajemi R, Gu H, Putter H, Zhang Y, Slieker RC, Stok AP, Thijssen PE, Müller F, van Zwet EW, Bock C, Meissner A, Lumey LH, Eline Slagboom P, Heijmans BT. Tobi EW, et al. Nat Commun. 2014 Nov 26;5:5592. doi: 10.1038/ncomms6592. Nat Commun. 2014. PMID: 25424739 Free PMC article.
However, a comprehensive assessment of the characteristics of prenatal malnutrition-associated differentially methylated regions (P-DMRs) is lacking in humans. ...P-DMRs located in INSR and CPT1A have enhancer activity in vitro and differential methylation is associated wi …
However, a comprehensive assessment of the characteristics of prenatal malnutrition-associated differentially methylated regions (P-D …
Effects of prenatal exposure to the Dutch famine on adult disease in later life: an overview.
Roseboom TJ, van der Meulen JH, Ravelli AC, Osmond C, Barker DJ, Bleker OP. Roseboom TJ, et al. Mol Cell Endocrinol. 2001 Dec 20;185(1-2):93-8. doi: 10.1016/s0303-7207(01)00721-3. Mol Cell Endocrinol. 2001. PMID: 11738798 Review.
It is thought that undernutrition of the fetus during critical periods of development would lead to adaptations in the structure and physiology of the fetal body, and thereby increase the risk of diseases in later life. The Dutch famine--though a historical disaster--provi …
It is thought that undernutrition of the fetus during critical periods of development would lead to adaptations in the structure and physiol …
Transgenerational effects of prenatal exposure to the 1944-45 Dutch famine.
Veenendaal MV, Painter RC, de Rooij SR, Bossuyt PM, van der Post JA, Gluckman PD, Hanson MA, Roseboom TJ. Veenendaal MV, et al. BJOG. 2013 Apr;120(5):548-53. doi: 10.1111/1471-0528.12136. Epub 2013 Jan 24. BJOG. 2013. PMID: 23346894
MAIN OUTCOME MEASURES: Weight, body mass index (BMI), and health in F2 adults, according to F1 prenatal famine exposure. RESULTS: Adult offspring (F2) of prenatally exposed F1 fathers had higher weights and BMIs than offspring of prenatally unexposed F …
MAIN OUTCOME MEASURES: Weight, body mass index (BMI), and health in F2 adults, according to F1 prenatal famine exposure. RESUL …
Hungry in the womb: what are the consequences? Lessons from the Dutch famine.
Roseboom TJ, Painter RC, van Abeelen AF, Veenendaal MV, de Rooij SR. Roseboom TJ, et al. Maturitas. 2011 Oct;70(2):141-5. doi: 10.1016/j.maturitas.2011.06.017. Epub 2011 Jul 28. Maturitas. 2011. PMID: 21802226 Review.
An increasing body of evidence suggests that poor nutrition at the very beginning of life - even before birth - leads to large and long term negative consequences for both mental and physical health. This paper reviews the evidence from studies on the Dutch famine, which i …
An increasing body of evidence suggests that poor nutrition at the very beginning of life - even before birth - leads to large and long term …
Prenatal famine exposure and mental health in later midlife.
van den Broek T, Fleischmann M. van den Broek T, et al. Aging Ment Health. 2019 Feb;23(2):166-170. doi: 10.1080/13607863.2017.1402293. Epub 2017 Nov 10. Aging Ment Health. 2019. PMID: 29125320
OBJECTIVES: Maternal malnutrition during pregnancy may have long-lasting effects on offspring's mental health. We investigate the effect of prenatal exposure to the Dutch famine (mid November 1944 to late April 1945) on mental health in later mid-life. ...We use dif …
OBJECTIVES: Maternal malnutrition during pregnancy may have long-lasting effects on offspring's mental health. We investigate the effect of …
Prenatal famine and adult health.
Lumey LH, Stein AD, Susser E. Lumey LH, et al. Annu Rev Public Health. 2011;32:237-62. doi: 10.1146/annurev-publhealth-031210-101230. Annu Rev Public Health. 2011. PMID: 21219171 Free PMC article. Review.
The studies show consistent associations between prenatal famine and adult body size, diabetes, and schizophrenia. For other measures of adult health, findings are less robust. A relation between prenatal famine and some reported epigenetic changes may …
The studies show consistent associations between prenatal famine and adult body size, diabetes, and schizophrenia. For other m …
DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific.
Tobi EW, Lumey LH, Talens RP, Kremer D, Putter H, Stein AD, Slagboom PE, Heijmans BT. Tobi EW, et al. Hum Mol Genet. 2009 Nov 1;18(21):4046-53. doi: 10.1093/hmg/ddp353. Epub 2009 Aug 4. Hum Mol Genet. 2009. PMID: 19656776 Free PMC article.
Prenatal famine in humans has been associated with various later-life consequences, depending on the gestational timing of the insult and the sex of the exposed individual. ...Indeed, animal studies and our early human data on the imprinted IGF2 locus indicated a li
Prenatal famine in humans has been associated with various later-life consequences, depending on the gestational timing of the
Late-life brain perfusion after prenatal famine exposure.
de Rooij SR, Mutsaerts HJMM, Petr J, Asllani I, Caan MWA, Groot P, Nederveen AJ, Schwab M, Roseboom TJ. de Rooij SR, et al. Neurobiol Aging. 2019 Oct;82:1-9. doi: 10.1016/j.neurobiolaging.2019.06.012. Epub 2019 Jul 8. Neurobiol Aging. 2019. PMID: 31376728 Free article.
Early nutritional deprivation may cause irreversible damage to the brain and seems to affect cognitive function in older age. We investigated whether prenatal undernutrition was associated with brain perfusion differences in older age. ...The latter seemed largely mediated …
Early nutritional deprivation may cause irreversible damage to the brain and seems to affect cognitive function in older age. We investigate …
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