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Page 1
Did you mean pre apoptotic proteins (4,823 results)?
Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax.
Li J, Sun X, Yang N, Ni J, Xie H, Guo H, Wang X, Zhou L, Liu J, Chen S, Wang X, Zhang Y, Yu C, Zhang W, Lu L. Li J, et al. Kidney Int. 2023 Jan;103(1):115-133. doi: 10.1016/j.kint.2022.08.022. Epub 2022 Sep 8. Kidney Int. 2023. PMID: 36089186
Knockdown of PGAM5 inhibited the hypoxia/reoxygenation-induced cytosolic release of mitochondrial DNA (mtDNA) and binding of mtDNA with the cellular DNA receptor cGAS in cultured cells. cGAS deficiency also attenuated the inflammation and kidney injury in AKI. Mechanistically, as …
Knockdown of PGAM5 inhibited the hypoxia/reoxygenation-induced cytosolic release of mitochondrial DNA (mtDNA) and binding of mtDNA with the …
The ARTS of p53-dependent mitochondrial apoptosis.
Hao Q, Chen J, Lu H, Zhou X. Hao Q, et al. J Mol Cell Biol. 2023 Mar 29;14(10):mjac074. doi: 10.1093/jmcb/mjac074. J Mol Cell Biol. 2023. PMID: 36565718 Free PMC article. Review.
The tumor-suppressive activity of p53 is largely attributed to its ability to induce cell death, including apoptosis, through transcription-dependent and transcription-independent mechanisms. On the one hand, nuclear p53 transcriptionally activates the expression of a myri …
The tumor-suppressive activity of p53 is largely attributed to its ability to induce cell death, including apoptosis, through transcr …
BCL-2 protein family: attractive targets for cancer therapy.
Kaloni D, Diepstraten ST, Strasser A, Kelly GL. Kaloni D, et al. Apoptosis. 2023 Feb;28(1-2):20-38. doi: 10.1007/s10495-022-01780-7. Epub 2022 Nov 7. Apoptosis. 2023. PMID: 36342579 Free PMC article. Review.
Acquired resistance to cell death is a hallmark of cancer. The BCL-2 protein family members play important roles in controlling apoptotic cell death. Abnormal over-expression of pro-survival BCL-2 family members or abnormal reduction of pro-apoptoti …
Acquired resistance to cell death is a hallmark of cancer. The BCL-2 protein family members play important roles in controlling ap …
Insights into the structure and protein-protein interactions of the pro-apoptotic protein ASPP2.
Rotem S, Katz C, Friedler A. Rotem S, et al. Biochem Soc Trans. 2007 Nov;35(Pt 5):966-9. doi: 10.1042/BST0350966. Biochem Soc Trans. 2007. PMID: 17956256 Review.
ASPP (apoptosis-stimulating protein of p53) 2 is a pro-apoptotic protein that stimulates the p53-mediated apoptotic response. ...The Ank-SH3 domains mediate interactions between ASPP2 and numerous proteins involved in apoptosis …
ASPP (apoptosis-stimulating protein of p53) 2 is a pro-apoptotic protein that stimulates the p53-mediated …
Stepwise activation of the pro-apoptotic protein Bid at mitochondrial membranes.
Hung CL, Chang HH, Lee SW, Chiang YW. Hung CL, et al. Cell Death Differ. 2021 Jun;28(6):1910-1925. doi: 10.1038/s41418-020-00716-5. Epub 2021 Jan 18. Cell Death Differ. 2021. PMID: 33462413 Free PMC article.
Caspase-8-cleaved Bid (cBid) associates with mitochondria and promotes the activation of BAX, leading to mitochondria outer membrane permeabilization (MOMP) and apoptosis. However, current structural models of cBid are largely based on studies using membrane vesicles and d …
Caspase-8-cleaved Bid (cBid) associates with mitochondria and promotes the activation of BAX, leading to mitochondria outer membrane permeab …
Plants expressing murine pro-apoptotic protein Bid do not have enhanced PCD.
Manara A, Imanifard Z, Fracasso L, Bellin D, Crimi M. Manara A, et al. BMC Res Notes. 2020 Sep 21;13(1):450. doi: 10.1186/s13104-020-05285-x. BMC Res Notes. 2020. PMID: 32957987 Free PMC article.
RESULTS: We have expressed the mouse pro-apoptotic protein Bid in Arabidopsis thaliana and in Nicotiana tabacum. We did not obtain any transformed plant constitutively expressing the truncated protein (tBid-i.e. the caspase-activated form) whereas ecto …
RESULTS: We have expressed the mouse pro-apoptotic protein Bid in Arabidopsis thaliana and in Nicotiana tabacum. We did …
Anti-Apoptotic and Pro-Apoptotic Bcl-2 Family Proteins in Peri-Implant Diseases.
Yilmaz D, Gürsoy M, Gürsoy UK. Yilmaz D, et al. Clin Oral Implants Res. 2023 Jun;34(6):582-590. doi: 10.1111/clr.14067. Epub 2023 Apr 10. Clin Oral Implants Res. 2023. PMID: 37035912 Free article.

RESULTS: The pro-apoptotic proteins; Bak, Bax and anti-apoptotic proteins Bcl-2, Bcl-xL, Mcl-1 were detected significantly higher in controls compared with patients with peri-implant mucositis and peri-implantitis (p < .001), respectively. Th

…
RESULTS: The pro-apoptotic proteins; Bak, Bax and anti-apoptotic proteins Bcl-2, Bcl-xL, Mcl-1 were detec …
Regulation of pro-apoptotic and anti-apoptotic factors in obesity-related esophageal adenocarcinoma.
Agrawal S, Podber A, Gillespie M, Dietz N, Hansen LA, Nandipati KC. Agrawal S, et al. Mol Biol Rep. 2024 Oct 12;51(1):1049. doi: 10.1007/s11033-024-09931-6. Mol Biol Rep. 2024. PMID: 39395071 Free PMC article.
The samples were analyzed for the expression levels of pro-apoptotic and anti-apoptotic factors, PKC-delta, cIAP2, FLIP, IGF-1, Akt, NF-kB and Ki67 by immunofluorescence and RT-PCR. ...RESULTS: Our results showed decreased gene and protein expression o …
The samples were analyzed for the expression levels of pro-apoptotic and anti-apoptotic factors, PKC-delta, cIAP2, FLIP …
Combined effect of the pro-apoptotic rhTRAIL protein and HSV-1 virus in head and neck cancer cell lines.
Bravo Perina L, Faria Gomes IN, Alcantara Pelloso AR, Silva VAO, Rebolho Batista Arantes LM, Eliseo Melendez M. Bravo Perina L, et al. Sci Rep. 2023 Oct 21;13(1):18023. doi: 10.1038/s41598-023-44888-9. Sci Rep. 2023. PMID: 37865660 Free PMC article.
Here we evaluated the combined effect of the pro-apoptotic protein rhTRAIL with the replication-competent wild-type HSV-1 virus in head and neck cancer cell lines. We observed a difference in the modulation profile of proteins related to apoptotic …
Here we evaluated the combined effect of the pro-apoptotic protein rhTRAIL with the replication-competent wild-type HSV …
Phosphorylation of the pro-apoptotic protein BIK: mapping of phosphorylation sites and effect on apoptosis.
Verma S, Zhao LJ, Chinnadurai G. Verma S, et al. J Biol Chem. 2001 Feb 16;276(7):4671-6. doi: 10.1074/jbc.M008983200. Epub 2000 Nov 17. J Biol Chem. 2001. PMID: 11084041 Free article.
BIK is a pro-apoptotic BCL-2 family member and is the founding member of a subfamily of pro-apoptotic proteins known as "BH3-alone" proteins. Ectopic expression of BIK induces apoptosis in variety of mammalian cells. BIK complexes …
BIK is a pro-apoptotic BCL-2 family member and is the founding member of a subfamily of pro-apoptotic protein …
169,447 results
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