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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1960 1
1961 3
1962 1
1963 2
1964 1
1968 1
1997 1
1999 1
2000 3
2002 1
2003 3
2004 11
2005 7
2006 3
2007 3
2008 13
2009 9
2010 9
2011 15
2012 7
2013 17
2014 13
2015 17
2016 18
2017 25
2018 34
2019 31
2020 47
2021 21
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282 results
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Page 1
Prolotherapy for Osteoarthritis and Tendinopathy: a Descriptive Review.
Rabago D, Nourani B. Rabago D, et al. Curr Rheumatol Rep. 2017 Jun;19(6):34. doi: 10.1007/s11926-017-0659-3. Curr Rheumatol Rep. 2017. PMID: 28484944 Review.
The development of new therapeutic options in both conditions is a public health priority. Prolotherapy is an injection-based outpatient regenerative therapy for chronic musculoskeletal conditions, including osteoarthritis and tendinopathy. The authors reviewed the basic s …
The development of new therapeutic options in both conditions is a public health priority. Prolotherapy is an injection-based outpati …
Dextrose Prolotherapy: A Narrative Review of Basic Science, Clinical Research, and Best Treatment Recommendations.
Reeves KD, Sit RW, Rabago DP. Reeves KD, et al. Phys Med Rehabil Clin N Am. 2016 Nov;27(4):783-823. doi: 10.1016/j.pmr.2016.06.001. Phys Med Rehabil Clin N Am. 2016. PMID: 27788902 Review.
A variety of solutions have been used; dextrose prolotherapy is the most rigorously studied and is the focus of this review. ...Research on the mechanism of action and clinical effects of dextrose prolotherapy are under way....
A variety of solutions have been used; dextrose prolotherapy is the most rigorously studied and is the focus of this review. ...Resea …
Hypertonic dextrose injections (prolotherapy) in the treatment of symptomatic knee osteoarthritis: A systematic review and meta-analysis.
Sit RW, Chung VCh, Reeves KD, Rabago D, Chan KK, Chan DC, Wu X, Ho RS, Wong SY. Sit RW, et al. Sci Rep. 2016 May 5;6:25247. doi: 10.1038/srep25247. Sci Rep. 2016. PMID: 27146849 Free PMC article. Review.
Hypertonic dextrose injections (prolotherapy) is an emerging treatment for symptomatic knee osteoarthritis (OA) but its efficacy is uncertain. ...Adequately powered, longer-term trials with uniform end points are needed to better elucidate the efficacy of prolotherapy
Hypertonic dextrose injections (prolotherapy) is an emerging treatment for symptomatic knee osteoarthritis (OA) but its efficacy is u …
Prolotherapy for the Thoracolumbar Myofascial System.
Fullerton BD. Fullerton BD. Phys Med Rehabil Clin N Am. 2018 Feb;29(1):125-138. doi: 10.1016/j.pmr.2017.08.010. Phys Med Rehabil Clin N Am. 2018. PMID: 29173658 Review.
Prolotherapy has focused on entheses as a key source of chronic low back pain, even without clear diagnosis of enthesopathy. ...Detailed case reports provide proof of concept for the 60-year history of prolotherapy in the treatment of chronic low back pain....
Prolotherapy has focused on entheses as a key source of chronic low back pain, even without clear diagnosis of enthesopathy. ...Detai
A Systematic Review of Dextrose Prolotherapy for Chronic Musculoskeletal Pain.
Hauser RA, Lackner JB, Steilen-Matias D, Harris DK. Hauser RA, et al. Clin Med Insights Arthritis Musculoskelet Disord. 2016 Jul 7;9:139-59. doi: 10.4137/CMAMD.S39160. eCollection 2016. Clin Med Insights Arthritis Musculoskelet Disord. 2016. PMID: 27429562 Free PMC article. Review.
OBJECTIVE: The aim of this study was to systematically review dextrose (d-glucose) prolotherapy efficacy in the treatment of chronic musculoskeletal pain. ...All 15 studies solely using subjective or psychometric measures reported positive findings. CONCLUSION: Use of dext …
OBJECTIVE: The aim of this study was to systematically review dextrose (d-glucose) prolotherapy efficacy in the treatment of chronic …
Prolotherapy: Potential for the Treatment of Chronic Wounds?
Siadat AH, Isseroff RR. Siadat AH, et al. Adv Wound Care (New Rochelle). 2019 Apr 1;8(4):160-167. doi: 10.1089/wound.2018.0866. Epub 2019 Apr 3. Adv Wound Care (New Rochelle). 2019. PMID: 31646060 Free PMC article. Review.
Multiple irritants are reported to be efficacious, but the focus here is on dextrose prolotherapy. In vitro and in vivo studies support translation to clinical use. ...Numerous clinical trials report pro-reparative effects of dextrose prolotherapy in joint diseases, …
Multiple irritants are reported to be efficacious, but the focus here is on dextrose prolotherapy. In vitro and in vivo studies suppo …
Effectiveness of prolotherapy in the treatment of chronic rotator cuff lesions.
Seven MM, Ersen O, Akpancar S, Ozkan H, Turkkan S, Yıldız Y, Koca K. Seven MM, et al. Orthop Traumatol Surg Res. 2017 May;103(3):427-433. doi: 10.1016/j.otsr.2017.01.003. Epub 2017 Feb 16. Orthop Traumatol Surg Res. 2017. PMID: 28215611 Free article. Clinical Trial.
HYPOTHESIS: Dextrose prolotherapy will reduce pain and improve shoulder function and patient satisfaction. ...Patients were divided into two groups: one treated with exercise (control group; n=60) and the other treated with prolotherapy injection (prolotherapy
HYPOTHESIS: Dextrose prolotherapy will reduce pain and improve shoulder function and patient satisfaction. ...Patients were divided i …
Prolotherapy injections and physiotherapy used singly and in combination for lateral epicondylalgia: a single-blinded randomised clinical trial.
Yelland M, Rabago D, Ryan M, Ng SK, Vithanachchi D, Manickaraj N, Bisset L. Yelland M, et al. BMC Musculoskelet Disord. 2019 Nov 3;20(1):509. doi: 10.1186/s12891-019-2905-5. BMC Musculoskelet Disord. 2019. PMID: 31679521 Free PMC article. Clinical Trial.
This trial aimed to compare the short- and long-term clinical effectiveness, cost effectiveness, and safety of prolotherapy used singly and in combination with physiotherapy. METHODS: Using a single-blinded randomised clinical trial design, 120 participants with lateral ep …
This trial aimed to compare the short- and long-term clinical effectiveness, cost effectiveness, and safety of prolotherapy used sing …
Prolotherapy for the patients with chronic musculoskeletal pain: systematic review and meta-analysis.
Bae G, Kim S, Lee S, Lee WY, Lim Y. Bae G, et al. Anesth Pain Med (Seoul). 2021 Jan;16(1):81-95. doi: 10.17085/apm.20078. Epub 2020 Dec 16. Anesth Pain Med (Seoul). 2021. PMID: 33348947 Free PMC article.
CONCLUSIONS: Dextrose prolotherapy is more effective in the treatment of chronic pain compared to saline injection or exercise. ...Adequately powered, homogeneous, and longer-term trials are needed to better elucidate the efficacy of prolotherapy....
CONCLUSIONS: Dextrose prolotherapy is more effective in the treatment of chronic pain compared to saline injection or exercise. ...Ad …
Prolotherapy: An effective therapy for Tietze syndrome.
Senturk E, Sahin E, Serter S. Senturk E, et al. J Back Musculoskelet Rehabil. 2017 Sep 22;30(5):975-978. doi: 10.3233/BMR-159269. J Back Musculoskelet Rehabil. 2017. PMID: 28505950
PURPOSE: To compare the short-term effect of prolotherapy and conservative terapy for the Tietze syndrome. PATIENTS AND METHODS: From 2013 to 2014, twenty-one patients underwent prolotherapy (group 1) and thirteen underwent conservative therapy with analgesics (grou …
PURPOSE: To compare the short-term effect of prolotherapy and conservative terapy for the Tietze syndrome. PATIENTS AND METHODS: From …
282 results
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