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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1971 1
1998 1
2000 2
2001 1
2004 2
2005 3
2006 3
2007 6
2008 5
2009 11
2010 17
2011 15
2012 18
2013 38
2014 51
2015 56
2016 71
2017 78
2018 128
2019 125
2020 196
2021 225
2022 238
2023 2
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1,127 results
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Page 1
Propionic Acid Shapes the Multiple Sclerosis Disease Course by an Immunomodulatory Mechanism.
Duscha A, Gisevius B, Hirschberg S, Yissachar N, Stangl GI, Eilers E, Bader V, Haase S, Kaisler J, David C, Schneider R, Troisi R, Zent D, Hegelmaier T, Dokalis N, Gerstein S, Del Mare-Roumani S, Amidror S, Staszewski O, Poschmann G, Stühler K, Hirche F, Balogh A, Kempa S, Träger P, Zaiss MM, Holm JB, Massa MG, Nielsen HB, Faissner A, Lukas C, Gatermann SG, Scholz M, Przuntek H, Prinz M, Forslund SK, Winklhofer KF, Müller DN, Linker RA, Gold R, Haghikia A. Duscha A, et al. Cell. 2020 Mar 19;180(6):1067-1080.e16. doi: 10.1016/j.cell.2020.02.035. Epub 2020 Mar 10. Cell. 2020. PMID: 32160527 Free article.
Short-chain fatty acids are processed from indigestible dietary fibers by gut bacteria and have immunomodulatory properties. Here, we investigate propionic acid (PA) in multiple sclerosis (MS), an autoimmune and neurodegenerative disease. ...Post-hoc analyses reveal …
Short-chain fatty acids are processed from indigestible dietary fibers by gut bacteria and have immunomodulatory properties. Here, we invest …
Impact of the Gut Microbiota on Intestinal Immunity Mediated by Tryptophan Metabolism.
Gao J, Xu K, Liu H, Liu G, Bai M, Peng C, Li T, Yin Y. Gao J, et al. Front Cell Infect Microbiol. 2018 Feb 6;8:13. doi: 10.3389/fcimb.2018.00013. eCollection 2018. Front Cell Infect Microbiol. 2018. PMID: 29468141 Free PMC article. Review.
Moreover, Trp, endogenous Trp metabolites (kynurenines, serotonin, and melatonin), and bacterial Trp metabolites (indole, indolic acid, skatole, and tryptamine) have profound effects on gut microbial composition, microbial metabolism, the host's immune system, the h …
Moreover, Trp, endogenous Trp metabolites (kynurenines, serotonin, and melatonin), and bacterial Trp metabolites (indole, indolic acid
Gut microbiota-derived indole 3-propionic acid protects against radiation toxicity via retaining acyl-CoA-binding protein.
Xiao HW, Cui M, Li Y, Dong JL, Zhang SQ, Zhu CC, Jiang M, Zhu T, Wang B, Wang HC, Fan SJ. Xiao HW, et al. Microbiome. 2020 May 20;8(1):69. doi: 10.1186/s40168-020-00845-6. Microbiome. 2020. PMID: 32434586 Free PMC article.
RESULTS: FMT elevated the level of microbial-derived indole 3-propionic acid (IPA) in fecal pellets from irradiated mice. IPA replenishment via oral route attenuated hematopoietic system and gastrointestinal (GI) tract injuries intertwined with radiation exposure wi …
RESULTS: FMT elevated the level of microbial-derived indole 3-propionic acid (IPA) in fecal pellets from irradiated mice. IPA …
Formation of propionate and butyrate by the human colonic microbiota.
Louis P, Flint HJ. Louis P, et al. Environ Microbiol. 2017 Jan;19(1):29-41. doi: 10.1111/1462-2920.13589. Epub 2016 Dec 8. Environ Microbiol. 2017. PMID: 27928878 Review.
The human gut microbiota ferments dietary non-digestible carbohydrates into short-chain fatty acids (SCFA). ...The ecophysiology, including growth requirements and responses to environmental factors, of major propionate and butyrate producing bacteria are discussed in rela …
The human gut microbiota ferments dietary non-digestible carbohydrates into short-chain fatty acids (SCFA). ...The ecophysiology, inc …
Indole-3-propionic acid inhibits gut dysbiosis and endotoxin leakage to attenuate steatohepatitis in rats.
Zhao ZH, Xin FZ, Xue Y, Hu Z, Han Y, Ma F, Zhou D, Liu XL, Cui A, Liu Z, Liu Y, Gao J, Pan Q, Li Y, Fan JG. Zhao ZH, et al. Exp Mol Med. 2019 Sep 10;51(9):1-14. doi: 10.1038/s12276-019-0304-5. Exp Mol Med. 2019. PMID: 31506421 Free PMC article.
Microbial metabolites have emerged as critical components that mediate the metabolic effects of the gut microbiota. Here, we show that indole-3-propionic acid (IPA), a tryptophan metabolite produced by gut bacteria, is a potent anti-non-alcoholic steatohepati …
Microbial metabolites have emerged as critical components that mediate the metabolic effects of the gut microbiota. Here, we show tha …
Precision Microbiome Modulation with Discrete Dietary Fiber Structures Directs Short-Chain Fatty Acid Production.
Deehan EC, Yang C, Perez-Muñoz ME, Nguyen NK, Cheng CC, Triador L, Zhang Z, Bakal JA, Walter J. Deehan EC, et al. Cell Host Microbe. 2020 Mar 11;27(3):389-404.e6. doi: 10.1016/j.chom.2020.01.006. Epub 2020 Jan 30. Cell Host Microbe. 2020. PMID: 32004499 Free article. Clinical Trial.
Dietary fibers (DFs) impact the gut microbiome in ways often considered beneficial. However, it is unknown if precise and predictable manipulations of the gut microbiota, and especially its metabolic activity, can be achieved through DFs with discrete chemical struc …
Dietary fibers (DFs) impact the gut microbiome in ways often considered beneficial. However, it is unknown if precise and predictable …
Short-Chain Fatty Acids, Maternal Microbiota and Metabolism in Pregnancy.
Ziętek M, Celewicz Z, Szczuko M. Ziętek M, et al. Nutrients. 2021 Apr 9;13(4):1244. doi: 10.3390/nu13041244. Nutrients. 2021. PMID: 33918804 Free PMC article. Review.
Short-chain fatty acids (SCFAs), as products of intestinal bacterial metabolism, are particularly relevant in the diagnosis of intestinal dysbiosis. The most common studies of microbiome metabolites include butyric acid, propionic acid and acetic ac
Short-chain fatty acids (SCFAs), as products of intestinal bacterial metabolism, are particularly relevant in the diagnosis of intestinal dy …
Gut microbiota mediates intermittent-fasting alleviation of diabetes-induced cognitive impairment.
Liu Z, Dai X, Zhang H, Shi R, Hui Y, Jin X, Zhang W, Wang L, Wang Q, Wang D, Wang J, Tan X, Ren B, Liu X, Zhao T, Wang J, Pan J, Yuan T, Chu C, Lan L, Yin F, Cadenas E, Shi L, Zhao S, Liu X. Liu Z, et al. Nat Commun. 2020 Feb 18;11(1):855. doi: 10.1038/s41467-020-14676-4. Nat Commun. 2020. PMID: 32071312 Free PMC article.
Moreover, strong connections are observed between IF affected genes, microbiota and metabolites, as assessed by integrative modelling. Removing gut microbiota with antibiotics partly abolishes the neuroprotective effects of IF. Administration of 3-indolepropionic …
Moreover, strong connections are observed between IF affected genes, microbiota and metabolites, as assessed by integrative modelling …
Microbial regulation of organismal energy homeostasis.
Cani PD, Van Hul M, Lefort C, Depommier C, Rastelli M, Everard A. Cani PD, et al. Nat Metab. 2019 Jan;1(1):34-46. doi: 10.1038/s42255-018-0017-4. Epub 2019 Jan 7. Nat Metab. 2019. PMID: 32694818 Review.
The gut microbiome has emerged as a key regulator of host metabolism. Here we review the various mechanisms through which the gut microbiome influences the energy metabolism of its host, highlighting the complex interactions between gut microbes, their metabolites a …
The gut microbiome has emerged as a key regulator of host metabolism. Here we review the various mechanisms through which the gut …
GC-MS Analysis of Short-Chain Fatty Acids in Feces, Cecum Content, and Blood Samples.
Hoving LR, Heijink M, van Harmelen V, van Dijk KW, Giera M. Hoving LR, et al. Methods Mol Biol. 2018;1730:247-256. doi: 10.1007/978-1-4939-7592-1_17. Methods Mol Biol. 2018. PMID: 29363078
Short-chain fatty acids, the end products of fermentation of dietary fibers by the gut microbiota, have been shown to exert multiple effects on mammalian metabolism. ...Here, we describe a fast, reliable, and reproducible method for the separation and quantification of sho …
Short-chain fatty acids, the end products of fermentation of dietary fibers by the gut microbiota, have been shown to exert multiple …
1,127 results