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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 1
1956 1
1957 2
1959 2
1960 1
1961 2
1962 2
1963 2
1964 12
1965 9
1966 6
1967 19
1968 32
1969 26
1970 49
1971 48
1972 73
1973 62
1974 109
1975 242
1976 221
1977 206
1978 241
1979 282
1980 361
1981 380
1982 461
1983 546
1984 632
1985 637
1986 734
1987 676
1988 847
1989 1061
1990 1125
1991 1232
1992 1419
1993 1464
1994 1704
1995 1861
1996 1937
1997 2145
1998 2386
1999 2676
2000 2992
2001 3120
2002 3383
2003 3666
2004 3927
2005 3804
2006 4045
2007 3886
2008 4100
2009 4037
2010 4115
2011 4204
2012 4442
2013 4372
2014 4159
2015 4116
2016 3824
2017 3648
2018 3478
2019 3632
2020 3431
2021 3406
2022 2967
2023 2756
2024 3053
2025 3497
2026 2180

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114,311 results

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Page 1
Imaging intracellular fluorescent proteins at nanometer resolution.
Betzig E, Patterson GH, Sougrat R, Lindwasser OW, Olenych S, Bonifacino JS, Davidson MW, Lippincott-Schwartz J, Hess HF. Betzig E, et al. Science. 2006 Sep 15;313(5793):1642-5. doi: 10.1126/science.1127344. Epub 2006 Aug 10. Science. 2006. PMID: 16902090
We introduce a method for optically imaging intracellular proteins at nanometer spatial resolution. Numerous sparse subsets of photoactivatable fluorescent protein molecules were activated, localized (to approximately 2 to 25 nanometers), and then bleached. . …
We introduce a method for optically imaging intracellular proteins at nanometer spatial resolution. Numerous sparse subsets of photoa …
A plasma membrane localized protein phosphatase in Toxoplasma gondii, PPM5C, regulates attachment to host cells.
Yang C, Broncel M, Dominicus C, Sampson E, Blakely WJ, Treeck M, Arrizabalaga G. Yang C, et al. Sci Rep. 2019 Apr 11;9(1):5924. doi: 10.1038/s41598-019-42441-1. Sci Rep. 2019. PMID: 30976120 Free PMC article.
In this study, we focused on the five protein phosphatases that are predicted to be membrane-associated either integrally or peripherally. We have determined that of these only PPM5C, a PP2C family member, localizes to the plasma membrane of Tox …
In this study, we focused on the five protein phosphatases that are predicted to be membrane-associated either integrally or p …
The Cwr1 protein kinase localizes to the plasma membrane and mediates resistance to cell wall stress in Candida albicans.
Naseem S, Zahumenský J, Lanze CE, Douglas LM, Malínský J, Konopka JB. Naseem S, et al. mSphere. 2024 Dec 19;9(12):e0039124. doi: 10.1128/msphere.00391-24. Epub 2024 Nov 29. mSphere. 2024. PMID: 39611854 Free PMC article.
The Cwr1 protein shows strong similarity to protein kinases, suggesting it plays a regulatory role in coordinating plasma membrane and cell wall functions. A Cwr1-green fluorescent protein (GFP) fusion protein localized to p …
The Cwr1 protein shows strong similarity to protein kinases, suggesting it plays a regulatory role in coordinating plasma …
Dynamic localization of the Na+-HCO3- co-transporter NBCn1 to the plasma membrane, centrosomes, spindle and primary cilia.
Severin M, Pedersen EL, Borre MT, Axholm I, Christiansen FB, Ponniah M, Czaplinska D, Larsen T, Pardo LA, Pedersen SF. Severin M, et al. J Cell Sci. 2023 Apr 1;136(7):jcs260687. doi: 10.1242/jcs.260687. Epub 2023 Apr 11. J Cell Sci. 2023. PMID: 37039101
Finely tuned regulation of transport protein localization is vital for epithelial function. The Na+-HCO3- co-transporter NBCn1 (also known as SLC4A7) is a key contributor to epithelial pH homeostasis, yet the regulation of its subcellular localization is not …
Finely tuned regulation of transport protein localization is vital for epithelial function. The Na+-HCO3- co-transporter NBCn1 …
The ERM-1 membrane-binding domain directs erm-1 mRNA localization to the plasma membrane in the C. elegans embryo.
Winkenbach LP, Parker DM, Williams RTP, Nishimura EO. Winkenbach LP, et al. Development. 2022 Nov 15;149(22):dev200930. doi: 10.1242/dev.200930. Epub 2022 Nov 18. Development. 2022. PMID: 36314842 Free PMC article.
mRNA localization and transport are integral in regulating gene expression. In Caenorhabditis elegans embryos, the maternally inherited mRNA erm-1 (Ezrin/Radixin/Moesin) becomes concentrated in anterior blastomeres. erm-1 mRNA localizes within those blastomeres to t …
mRNA localization and transport are integral in regulating gene expression. In Caenorhabditis elegans embryos, the maternally inherit …
Steric exclusion and protein conformation determine the localization of plasma membrane transporters.
Bianchi F, Syga Ł, Moiset G, Spakman D, Schavemaker PE, Punter CM, Seinen AB, van Oijen AM, Robinson A, Poolman B. Bianchi F, et al. Nat Commun. 2018 Feb 5;9(1):501. doi: 10.1038/s41467-018-02864-2. Nat Commun. 2018. PMID: 29402931 Free PMC article.
The plasma membrane (PM) of Saccharomyces cerevisiae contains membrane compartments, MCC/eisosomes and MCPs, named after the protein residents Can1 and Pma1, respectively. ...Our data indicate that the mobile fraction of all integral plasma m …
The plasma membrane (PM) of Saccharomyces cerevisiae contains membrane compartments, MCC/eisosomes and MCPs, named afte …
Multiple plasma membrane reporters discern LHFPL5 region that blocks trafficking to the plasma membrane.
Soler DC, Ballesteros A, Sloan AE, McCormick TS, Stepanyan R. Soler DC, et al. Sci Rep. 2023 Feb 13;13(1):2528. doi: 10.1038/s41598-023-28045-w. Sci Rep. 2023. PMID: 36781873 Free PMC article.
Despite localizing to the plasma membrane of stereocilia, the mechanosensing organelles of hair cells, LHFPL5 requires its binding partner within the MET complex, PCDH15, to localize to the stereocilia tips in hair cells and to the plasma mem …
Despite localizing to the plasma membrane of stereocilia, the mechanosensing organelles of hair cells, LHFPL5 requires …
SEC18/NSF-independent, protein-sorting pathway from the yeast cortical ER to the plasma membrane.
Jüschke C, Wächter A, Schwappach B, Seedorf M. Jüschke C, et al. J Cell Biol. 2005 May 23;169(4):613-22. doi: 10.1083/jcb.200503033. J Cell Biol. 2005. PMID: 15911878 Free PMC article.
The yeast protein Ist2p, which is synthesized from a localized mRNA, travels from the ER to the plasma membrane via a novel route that operates independently of the formation of coat protein complex II-coated vesicles. ...Based on these observat …
The yeast protein Ist2p, which is synthesized from a localized mRNA, travels from the ER to the plasma membrane …
TORC2 plasma membrane localization is essential for cell viability and restricted to a distinct domain.
Berchtold D, Walther TC. Berchtold D, et al. Mol Biol Cell. 2009 Mar;20(5):1565-75. doi: 10.1091/mbc.e08-10-1001. Epub 2009 Jan 14. Mol Biol Cell. 2009. PMID: 19144819 Free PMC article.
Here, we show that TORC1 and TORC2 have different localizations in Saccharomyces cerevisiae. TORC1 is localized exclusively to the vacuolar membrane, whereas TORC2 is localized dynamically in a previously unrecognized plasma membrane doma …
Here, we show that TORC1 and TORC2 have different localizations in Saccharomyces cerevisiae. TORC1 is localized exclusively to …
114,311 results
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