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Year Number of Results
2005 2
2007 1
2010 1
2011 1
2017 1
2019 2
2022 1
2023 0
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9 results
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Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma.
Jiang Y, Sun A, Zhao Y, Ying W, Sun H, Yang X, Xing B, Sun W, Ren L, Hu B, Li C, Zhang L, Qin G, Zhang M, Chen N, Zhang M, Huang Y, Zhou J, Zhao Y, Liu M, Zhu X, Qiu Y, Sun Y, Huang C, Yan M, Wang M, Liu W, Tian F, Xu H, Zhou J, Wu Z, Shi T, Zhu W, Qin J, Xie L, Fan J, Qian X, He F; Chinese Human Proteome Project (CNHPP) Consortium. Jiang Y, et al. Nature. 2019 Mar;567(7747):257-261. doi: 10.1038/s41586-019-0987-8. Epub 2019 Feb 27. Nature. 2019. PMID: 30814741
Here, using proteomic and phospho-proteomic profiling, we characterize 110 paired tumour and non-tumour tissues of clinical early-stage hepatocellular carcinoma related to hepatitis B virus infection. ...The proteomic stratificatio …
Here, using proteomic and phospho-proteomic profiling, we characterize 110 paired tumour and non-tumour tissues of clinical …
Proteomics of hepatocellular carcinoma in Chinese patients.
Luk JM, Liu AM. Luk JM, et al. OMICS. 2011 May;15(5):261-6. doi: 10.1089/omi.2010.0099. Epub 2011 Feb 24. OMICS. 2011. PMID: 21348761 Free article. Review.
Such new horizons of integrated profiling informatics have allowed us to search for and better identify clinically useful biomarkers and therapeutic targets for cancers including HCC. Capitalizing the large clinical samples cohort (over 100 pairs of tu …
Such new horizons of integrated profiling informatics have allowed us to search for and better identify clinically useful biom …
Combined Analysis of Metabolomes, Proteomes, and Transcriptomes of Hepatitis C Virus-Infected Cells and Liver to Identify Pathways Associated With Disease Development.
Lupberger J, Croonenborghs T, Roca Suarez AA, Van Renne N, Jühling F, Oudot MA, Virzì A, Bandiera S, Jamey C, Meszaros G, Brumaru D, Mukherji A, Durand SC, Heydmann L, Verrier ER, El Saghire H, Hamdane N, Bartenschlager R, Fereshetian S, Ramberger E, Sinha R, Nabian M, Everaert C, Jovanovic M, Mertins P, Carr SA, Chayama K, Dali-Youcef N, Ricci R, Bardeesy NM, Fujiwara N, Gevaert O, Zeisel MB, Hoshida Y, Pochet N, Baumert TF. Lupberger J, et al. Gastroenterology. 2019 Aug;157(2):537-551.e9. doi: 10.1053/j.gastro.2019.04.003. Epub 2019 Apr 9. Gastroenterology. 2019. PMID: 30978357 Free PMC article.
Using differential expression, gene set enrichment analyses, and protein interaction mapping, we identified pathways that changed in response to HCV infection. We validated our findings in studies of liver tissues from 216 patients with HCV infection and early-st …
Using differential expression, gene set enrichment analyses, and protein interaction mapping, we identified pathways that changed in …
Treatment of hepatocellular carcinoma.
Blum HE. Blum HE. Best Pract Res Clin Gastroenterol. 2005 Feb;19(1):129-45. doi: 10.1016/j.bpg.2004.11.008. Best Pract Res Clin Gastroenterol. 2005. PMID: 15757809 Review.
Hepatocellular carcinoma (HCC) is one of the most common malignant tumours worldwide. ...New technologies, including gene expression profiling and proteomic analyses, should further elucidate the molecular events underlying HCC development and ident …
Hepatocellular carcinoma (HCC) is one of the most common malignant tumours worldwide. ...New technologies, including ge …
Quantitative proteomics identification of phosphoglycerate mutase 1 as a novel therapeutic target in hepatocellular carcinoma.
Ren F, Wu H, Lei Y, Zhang H, Liu R, Zhao Y, Chen X, Zeng D, Tong A, Chen L, Wei Y, Huang C. Ren F, et al. Mol Cancer. 2010 Apr 19;9:81. doi: 10.1186/1476-4598-9-81. Mol Cancer. 2010. PMID: 20403181 Free PMC article.
There is an urgent need to develop novel biomarkers for early diagnosis, as well as to identify new drug targets for therapeutic interventions. ...CONCLUSION: Our studies suggested that PGAM1 plays an important role in hepatocarcinogenesis, and …
There is an urgent need to develop novel biomarkers for early diagnosis, as well as to identify new drug targets …
Hepatocellular carcinoma: an update.
Blum HE, Spangenberg HC. Blum HE, et al. Arch Iran Med. 2007 Jul;10(3):361-71. Arch Iran Med. 2007. PMID: 17604475 Review.
Hepatocellular carcinoma is one of the most common malignant tumors worldwide. ...New technologies, including gene expression profiling and proteomic analyses, should allow to further elucidate the molecular events underlying hepatocellular c …
Hepatocellular carcinoma is one of the most common malignant tumors worldwide. ...New technologies, including gene expr …
Hepatocellular carcinoma: therapy and prevention.
Blum HE. Blum HE. World J Gastroenterol. 2005 Dec 21;11(47):7391-400. doi: 10.3748/wjg.v11.i47.7391. World J Gastroenterol. 2005. PMID: 16437707 Free PMC article. Review.
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide. ...New technologies, including gene expression profiling and proteomic analyses, should allow to further elucidate the molecular events underlying HCC development and …
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide. ...New technologies, including gen …
HBV cccDNA-A Culprit and Stumbling Block for the Hepatitis B Virus Infection: Its Presence in Hepatocytes Perplexed the Possible Mission for a Functional Cure.
Bhat SA, Kazim SN. Bhat SA, et al. ACS Omega. 2022 Jul 7;7(28):24066-24081. doi: 10.1021/acsomega.2c02216. eCollection 2022 Jul 19. ACS Omega. 2022. PMID: 35874215 Free PMC article. Review.
It has been linked to the development of liver cirrhosis and hepatocellular carcinoma and can trigger different types of liver damage. ...Though cccDNA approaches for direct targeting are still in the early stages of development, the assembly of …
It has been linked to the development of liver cirrhosis and hepatocellular carcinoma and can trigger different types of liver …
Transglutaminase 2 is upregulated in primary hepatocellular carcinoma with early recurrence as determined by proteomic profiles.
Yamaguchi H, Kuroda K, Sugitani M, Takayama T, Hasegawa K, Esumi M. Yamaguchi H, et al. Int J Oncol. 2017 May;50(5):1749-1759. doi: 10.3892/ijo.2017.3917. Epub 2017 Mar 20. Int J Oncol. 2017. PMID: 28339069
The mechanism of early recurrence of hepato-cellular carcinoma (HCC) is not well understood. ...The proteomics of strictly classified HCCs would be useful for characterizing pro-metastatic HCC and for developing a new therapeutic target f …
The mechanism of early recurrence of hepato-cellular carcinoma (HCC) is not well understood. ...The proteomics of stric …