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Year Number of Results
1987 2
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2001 4
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255 results

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Page 1
Vitamin B12 Deficiency: Recognition and Management.
Langan RC, Goodbred AJ. Langan RC, et al. Am Fam Physician. 2017 Sep 15;96(6):384-389. Am Fam Physician. 2017. PMID: 28925645 Free article.
Screening average-risk adults for vitamin B12 deficiency is not recommended. Screening may be warranted in patients with one or more risk factors, such as gastric or small intestine resections, inflammatory bowel disease, use of metformin for more than four months, …
Screening average-risk adults for vitamin B12 deficiency is not recommended. Screening may be warranted in patients with one o …
Vitamin B12 deficiency and use of proton pump inhibitors: a systematic review and meta-analysis.
Choudhury A, Jena A, Jearth V, Dutta AK, Makharia G, Dutta U, Goenka M, Kochhar R, Sharma V. Choudhury A, et al. Expert Rev Gastroenterol Hepatol. 2023 May;17(5):479-487. doi: 10.1080/17474124.2023.2204229. Epub 2023 Apr 19. Expert Rev Gastroenterol Hepatol. 2023. PMID: 37060552
BACKGROUND: Proton pump inhibitors (PPI) may impact the absorption of vitamin B12. We performed a systematic review to ascertain if PPI use increases risk of vitamin B12 deficiency. ...We selected studies that compared the frequenc …
BACKGROUND: Proton pump inhibitors (PPI) may impact the absorption of vitamin B12. We performed a systema …
Association of long-term proton pump inhibitor therapy with bone fractures and effects on absorption of calcium, vitamin B12, iron, and magnesium.
Ito T, Jensen RT. Ito T, et al. Curr Gastroenterol Rep. 2010 Dec;12(6):448-57. doi: 10.1007/s11894-010-0141-0. Curr Gastroenterol Rep. 2010. PMID: 20882439 Free PMC article. Review.
Proton pump inhibitors (PPI) are one of the most widely used classes of drugs. PPIs have a very favorable safety profile, and it is unusual for a patient to stop them because of side effects. ...
Proton pump inhibitors (PPI) are one of the most widely used classes of drugs. PPIs have a very favorable safety profil …
Vitamin B12 Deficiency: Common Questions and Answers.
Patel H, McGuirk R. Patel H, et al. Am Fam Physician. 2025 Sep;112(3):294-300. Am Fam Physician. 2025. PMID: 40961307 Review.
Vitamin B12 deficiency occurs in approximately 2% to 3% of adults in the United States. Risk factors include malabsorptive processes, limited dietary intake of vitamin B12, use of certain medications (eg, metformin, proton pump inhibit …
Vitamin B12 deficiency occurs in approximately 2% to 3% of adults in the United States. Risk factors include malabsorptive pro …
Long-Term Proton Pump Inhibitor-Acid Suppressive Treatment Can Cause Vitamin B(12) Deficiency in Zollinger-Ellison Syndrome (ZES) Patients.
Ito T, Ramos-Alvarez I, Jensen RT. Ito T, et al. Int J Mol Sci. 2024 Jul 2;25(13):7286. doi: 10.3390/ijms25137286. Int J Mol Sci. 2024. PMID: 39000391 Free PMC article.
Whether the long-term treatment of patients with proton pump inhibitors (PPIs) with different diseases [GERD, Zollinger-Ellison syndrome (ZES), etc.] can result in vitamin B(12) (VB(12)) deficiency is controversial. ...
Whether the long-term treatment of patients with proton pump inhibitors (PPIs) with different diseases [GERD, Zollinger …
The Risks and Benefits of Long-term Use of Proton Pump Inhibitors: Expert Review and Best Practice Advice From the American Gastroenterological Association.
Freedberg DE, Kim LS, Yang YX. Freedberg DE, et al. Gastroenterology. 2017 Mar;152(4):706-715. doi: 10.1053/j.gastro.2017.01.031. Gastroenterology. 2017. PMID: 28257716 Review.
BACKGROUND & AIMS: The purpose of this review is to evaluate the risks associated with long-term use of proton pump inhibitors (PPIs), focusing on long-term use of PPIs for three common indications: gastroesophageal reflux disease (GERD), Barrett's esopha …
BACKGROUND & AIMS: The purpose of this review is to evaluate the risks associated with long-term use of proton pump inh …
Association Between Long-Term Proton Pump Inhibitor Therapy and Vitamin B12 Status: A Systematic Review and Meta-Analysis.
Parnham O, Patient W. Parnham O, et al. Cureus. 2025 Aug 13;17(8):e90038. doi: 10.7759/cureus.90038. eCollection 2025 Aug. Cureus. 2025. PMID: 40823471 Free PMC article. Review.
Proton pump inhibitors (PPIs) are widely prescribed medications that have been linked to vitamin B12 deficiency. ...There was no association between chronic PPI use and vitamin B12 deficiency when assessing total serum vitamin …
Proton pump inhibitors (PPIs) are widely prescribed medications that have been linked to vitamin B12 defi …
Metformin-Induced Vitamin B12 Deficiency in Patients With Type-2 Diabetes Mellitus.
Tiwari A, Kumar Singh R, Satone PD, Meshram RJ. Tiwari A, et al. Cureus. 2023 Oct 26;15(10):e47771. doi: 10.7759/cureus.47771. eCollection 2023 Oct. Cureus. 2023. PMID: 38034222 Free PMC article. Review.
Various studies also show a relation between vitamin B12 insufficiency and metformin-treated T2DM patients as decreased absorption of vitamin B12. There could be a severe complication of vitamin B12 deficiency in T2DM patients. The use of …
Various studies also show a relation between vitamin B12 insufficiency and metformin-treated T2DM patients as decreased absorp …
Proton Pump Inhibitors (PPIs)-An Evidence-Based Review of Indications, Efficacy, Harms, and Deprescribing.
Andrawes M, Andrawes W, Das A, Siau K. Andrawes M, et al. Medicina (Kaunas). 2025 Aug 31;61(9):1569. doi: 10.3390/medicina61091569. Medicina (Kaunas). 2025. PMID: 41010960 Free PMC article. Review.
Proton pump inhibitors (PPIs) are among the most prescribed drugs worldwide owing to their proven efficacy in symptom control and mucosal healing for acid-related disorders including gastroesophageal reflux disease (GORD), peptic ulcer disease, Helicobacter p …
Proton pump inhibitors (PPIs) are among the most prescribed drugs worldwide owing to their proven efficacy in symptom c …
Adverse Effects Associated with Long-Term Use of Proton Pump Inhibitors.
Maideen NMP. Maideen NMP. Chonnam Med J. 2023 May;59(2):115-127. doi: 10.4068/cmj.2023.59.2.115. Epub 2023 May 25. Chonnam Med J. 2023. PMID: 37303818 Free PMC article. Review.
Clinicians including prescribers and pharmacists should be aware of the adverse effects of taking proton pump inhibitors for an extended period of time. In addition, the patients taking proton pump inhibitors for long-term should be monit …
Clinicians including prescribers and pharmacists should be aware of the adverse effects of taking proton pump inhibitors …
255 results