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883 results

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Page 1
Psilocybin-assisted therapy for depression: A systematic review and meta-analysis.
Haikazian S, Chen-Li DCJ, Johnson DE, Fancy F, Levinta A, Husain MI, Mansur RB, McIntyre RS, Rosenblat JD. Haikazian S, et al. Psychiatry Res. 2023 Nov;329:115531. doi: 10.1016/j.psychres.2023.115531. Epub 2023 Oct 11. Psychiatry Res. 2023. PMID: 37844352 Review.
The aim of this review was to determine the effect of psilocybin on depressive symptoms in patients diagnosed with life-threatening illnesses or major depressive disorder. ...The primary outcome was the standardized mean difference (SMD) in depressi
The aim of this review was to determine the effect of psilocybin on depressive symptoms in patients diagnosed with life-threat …
Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression.
Goodwin GM, Aaronson ST, Alvarez O, Arden PC, Baker A, Bennett JC, Bird C, Blom RE, Brennan C, Brusch D, Burke L, Campbell-Coker K, Carhart-Harris R, Cattell J, Daniel A, DeBattista C, Dunlop BW, Eisen K, Feifel D, Forbes M, Haumann HM, Hellerstein DJ, Hoppe AI, Husain MI, Jelen LA, Kamphuis J, Kawasaki J, Kelly JR, Key RE, Kishon R, Knatz Peck S, Knight G, Koolen MHB, Lean M, Licht RW, Maples-Keller JL, Mars J, Marwood L, McElhiney MC, Miller TL, Mirow A, Mistry S, Mletzko-Crowe T, Modlin LN, Nielsen RE, Nielson EM, Offerhaus SR, O'Keane V, Páleníček T, Printz D, Rademaker MC, van Reemst A, Reinholdt F, Repantis D, Rucker J, Rudow S, Ruffell S, Rush AJ, Schoevers RA, Seynaeve M, Shao S, Soares JC, Somers M, Stansfield SC, Sterling D, Strockis A, Tsai J, Visser L, Wahba M, Williams S, Young AH, Ywema P, Zisook S, Malievskaia E. Goodwin GM, et al. N Engl J Med. 2022 Nov 3;387(18):1637-1648. doi: 10.1056/NEJMoa2206443. N Engl J Med. 2022. PMID: 36322843 Clinical Trial.
BACKGROUND: Psilocybin is being studied for use in treatment-resistant depression. METHODS: In this phase 2 double-blind trial, we randomly assigned adults with treatment-resistant depression to receive a single dose of a proprietary, synthetic formulation of …
BACKGROUND: Psilocybin is being studied for use in treatment-resistant depression. METHODS: In this phase 2 double-blind trial …
Molecular Mechanisms of Psilocybin and Implications for the Treatment of Depression.
Ling S, Ceban F, Lui LMW, Lee Y, Teopiz KM, Rodrigues NB, Lipsitz O, Gill H, Subramaniapillai M, Mansur RB, Lin K, Ho R, Rosenblat JD, Castle D, McIntyre RS. Ling S, et al. CNS Drugs. 2022 Jan;36(1):17-30. doi: 10.1007/s40263-021-00877-y. Epub 2021 Nov 17. CNS Drugs. 2022. PMID: 34791625 Review.
Preliminary studies with psilocybin have shown therapeutic promise across diverse populations including major depressive disorder. ...Along with the direct effects on neurochemical systems, psilocybin alters neural circuitry and key brain regions previ …
Preliminary studies with psilocybin have shown therapeutic promise across diverse populations including major depressive di
Trial of Psilocybin versus Escitalopram for Depression.
Carhart-Harris R, Giribaldi B, Watts R, Baker-Jones M, Murphy-Beiner A, Murphy R, Martell J, Blemings A, Erritzoe D, Nutt DJ. Carhart-Harris R, et al. N Engl J Med. 2021 Apr 15;384(15):1402-1411. doi: 10.1056/NEJMoa2032994. N Engl J Med. 2021. PMID: 33852780 Clinical Trial.
BACKGROUND: Psilocybin may have antidepressant properties, but direct comparisons between psilocybin and established treatments for depression are lacking. METHODS: In a phase 2, double-blind, randomized, controlled trial involving patients with long-standing …
BACKGROUND: Psilocybin may have antidepressant properties, but direct comparisons between psilocybin and established treatment …
Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial.
Griffiths RR, Johnson MW, Carducci MA, Umbricht A, Richards WA, Richards BD, Cosimano MP, Klinedinst MA. Griffiths RR, et al. J Psychopharmacol. 2016 Dec;30(12):1181-1197. doi: 10.1177/0269881116675513. J Psychopharmacol. 2016. PMID: 27909165 Free PMC article. Clinical Trial.
Cancer patients often develop chronic, clinically significant symptoms of depression and anxiety. Previous studies suggest that psilocybin may decrease depression and anxiety in cancer patients. The effects of psilocybin were studied in 51 cancer patie …
Cancer patients often develop chronic, clinically significant symptoms of depression and anxiety. Previous studies suggest that ps
Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study.
Carhart-Harris RL, Bolstridge M, Rucker J, Day CM, Erritzoe D, Kaelen M, Bloomfield M, Rickard JA, Forbes B, Feilding A, Taylor D, Pilling S, Curran VH, Nutt DJ. Carhart-Harris RL, et al. Lancet Psychiatry. 2016 Jul;3(7):619-27. doi: 10.1016/S2215-0366(16)30065-7. Epub 2016 May 17. Lancet Psychiatry. 2016. PMID: 27210031 Free article. Clinical Trial.
The primary outcome measure for feasibility was patient-reported intensity of psilocybin's effects. Patients were monitored for adverse reactions during the dosing sessions and subsequent clinic and remote follow-up. ...This trial is registered with ISRCTN, number I …
The primary outcome measure for feasibility was patient-reported intensity of psilocybin's effects. Patients were monitored fo …
Psychotherapy with Psilocybin for Depression: Systematic Review.
Dawood Hristova JJ, Pérez-Jover V. Dawood Hristova JJ, et al. Behav Sci (Basel). 2023 Mar 31;13(4):297. doi: 10.3390/bs13040297. Behav Sci (Basel). 2023. PMID: 37102811 Free PMC article. Review.
Psychopharmacological therapies with psychedelics, particularly those with psilocybin, are showing promising potential for the treatment of depression, among other conditions. ...The aim of this project was to provide experimental evidence about therapeutic procedur …
Psychopharmacological therapies with psychedelics, particularly those with psilocybin, are showing promising potential for the treatm …
Psilocybin in Treatment-Resistant Depression.
Madras BK. Madras BK. N Engl J Med. 2022 Nov 3;387(18):1708-1709. doi: 10.1056/NEJMe2210975. N Engl J Med. 2022. PMID: 36322849 No abstract available.
Psilocybin for depression.
De Giorgi R, Ede R. De Giorgi R, et al. BMJ. 2024 May 1;385:q798. doi: 10.1136/bmj.q798. BMJ. 2024. PMID: 38692675 No abstract available.
Psilocybin-assisted therapy for depression: A systematic review and dose-response meta-analysis of human studies.
Perez N, Langlest F, Mallet L, De Pieri M, Sentissi O, Thorens G, Seragnoli F, Zullino D, Kirschner M, Kaiser S, Solmi M, Sabé M. Perez N, et al. Eur Neuropsychopharmacol. 2023 Nov;76:61-76. doi: 10.1016/j.euroneuro.2023.07.011. Epub 2023 Aug 7. Eur Neuropsychopharmacol. 2023. PMID: 37557019 Free article. Review.
Psilocybin is increasingly studied for its antidepressant effect, but its optimal dosage for depression remains unclear. We conducted a systematic review and a dose-response meta-analysis to find the optimal dosage of psilocybin to reduce depression sc
Psilocybin is increasingly studied for its antidepressant effect, but its optimal dosage for depression remains unclear. We co
883 results