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1,258 results

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Page 1
Atopic Dermatitis and Psoriasis: Similarities and Differences in Metabolism and Microbiome.
Chen Y, Peng C, Zhu L, Wang J, Cao Q, Chen X, Li J. Chen Y, et al. Clin Rev Allergy Immunol. 2024 Jun;66(3):294-315. doi: 10.1007/s12016-024-08995-3. Epub 2024 Jul 2. Clin Rev Allergy Immunol. 2024. PMID: 38954264 Review.
Atopic dermatitis and psoriasis are common chronic inflammatory diseases of high incidence that share some clinical features, including symptoms of pruritus and pain, scaly lesions, and histologically, acanthosis and hyperkeratosis. ...Meanwhile, recent studi
Atopic dermatitis and psoriasis are common chronic inflammatory diseases of high incidence that share some clinical fea
Atopic dermatitis and psoriasis: two different immune diseases or one spectrum?
Guttman-Yassky E, Krueger JG. Guttman-Yassky E, et al. Curr Opin Immunol. 2017 Oct;48:68-73. doi: 10.1016/j.coi.2017.08.008. Epub 2017 Sep 1. Curr Opin Immunol. 2017. PMID: 28869867 Review.
Psoriasis and atopic dermatitis (AD) are common T-cell mediated inflammatory diseases of the skin that can be treated by specific cytokine antagonists or more broad immunosuppressive drugs. ...Today, 90% of psoriasis patients have extremely controlled
Psoriasis and atopic dermatitis (AD) are common T-cell mediated inflammatory diseases of the skin that can be treated b
Atopic Dermatitis Is an IL-13-Dominant Disease with Greater Molecular Heterogeneity Compared to Psoriasis.
Tsoi LC, Rodriguez E, Degenhardt F, Baurecht H, Wehkamp U, Volks N, Szymczak S, Swindell WR, Sarkar MK, Raja K, Shao S, Patrick M, Gao Y, Uppala R, Perez White BE, Getsios S, Harms PW, Maverakis E, Elder JT, Franke A, Gudjonsson JE, Weidinger S. Tsoi LC, et al. J Invest Dermatol. 2019 Jul;139(7):1480-1489. doi: 10.1016/j.jid.2018.12.018. Epub 2019 Jan 11. J Invest Dermatol. 2019. PMID: 30641038 Free PMC article.
Atopic dermatitis (AD) affects up to 20% of children and adults worldwide. To gain a deeper understanding of the pathophysiology of AD, we conducted a large-scale transcriptomic study of AD with deeply sequenced RNA-sequencing samples using long (126-bp) paired-end
Atopic dermatitis (AD) affects up to 20% of children and adults worldwide. To gain a deeper understanding of the pathophysiolo
The immunology of atopic dermatitis and its reversibility with broad-spectrum and targeted therapies.
Brunner PM, Guttman-Yassky E, Leung DY. Brunner PM, et al. J Allergy Clin Immunol. 2017 Apr;139(4S):S65-S76. doi: 10.1016/j.jaci.2017.01.011. J Allergy Clin Immunol. 2017. PMID: 28390479 Free PMC article. Review.
Atopic dermatitis (AD), the most common chronic inflammatory skin disease, is driven by both terminal keratinocyte differentiation defects and strong type 2 immune responses. In contrast to chronic plaque-type psoriasis, AD is now understood to be a much more
Atopic dermatitis (AD), the most common chronic inflammatory skin disease, is driven by both terminal keratinocyte differentia
Subtypes of atopic dermatitis: From phenotype to endotype.
Tokura Y, Hayano S. Tokura Y, et al. Allergol Int. 2022 Jan;71(1):14-24. doi: 10.1016/j.alit.2021.07.003. Epub 2021 Jul 31. Allergol Int. 2022. PMID: 34344611 Free article. Review.
Atopic dermatitis (AD) is a heterogenous disorder and can be classified into different types. ...While extrinsic AD is the major subtype possessing skin barrier impairment (high incidence of filaggrin mutations), intrinsic AD occupies about 20% of AD with female dom
Atopic dermatitis (AD) is a heterogenous disorder and can be classified into different types. ...While extrinsic AD is the maj
Beyond the dichotomy: understanding the overlap between atopic dermatitis and psoriasis.
Li M, Wang J, Liu Q, Liu Y, Mi W, Li W, Li J. Li M, et al. Front Immunol. 2025 Feb 10;16:1541776. doi: 10.3389/fimmu.2025.1541776. eCollection 2025. Front Immunol. 2025. PMID: 39995673 Free PMC article. Review.
Atopic dermatitis and psoriasis have traditionally been considered distinct inflammatory skin diseases with unique pathogenic mechanisms. ...This review comprehensively examines the complex relationship between psoriasis and atopic dermatitis
Atopic dermatitis and psoriasis have traditionally been considered distinct inflammatory skin diseases with unique path
Microbe-host interplay in atopic dermatitis and psoriasis.
Fyhrquist N, Muirhead G, Prast-Nielsen S, Jeanmougin M, Olah P, Skoog T, Jules-Clement G, Feld M, Barrientos-Somarribas M, Sinkko H, van den Bogaard EH, Zeeuwen PLJM, Rikken G, Schalkwijk J, Niehues H, Däubener W, Eller SK, Alexander H, Pennino D, Suomela S, Tessas I, Lybeck E, Baran AM, Darban H, Gangwar RS, Gerstel U, Jahn K, Karisola P, Yan L, Hansmann B, Katayama S, Meller S, Bylesjö M, Hupé P, Levi-Schaffer F, Greco D, Ranki A, Schröder JM, Barker J, Kere J, Tsoka S, Lauerma A, Soumelis V, Nestle FO, Homey B, Andersson B, Alenius H. Fyhrquist N, et al. Nat Commun. 2019 Oct 16;10(1):4703. doi: 10.1038/s41467-019-12253-y. Nat Commun. 2019. PMID: 31619666 Free PMC article.
Here we perform a comparative analysis of skin microbial communities coupled to global patterns of cutaneous gene expression in patients with atopic dermatitis or psoriasis. The skin microbiota is analysed by 16S amplicon or whole genome sequencing and the sk …
Here we perform a comparative analysis of skin microbial communities coupled to global patterns of cutaneous gene expression in patients wit …
Gut microbiota and skin pathologies: Mechanism of the gut-skin axis in atopic dermatitis and psoriasis.
Chen M, Wang R, Wang T. Chen M, et al. Int Immunopharmacol. 2024 Nov 15;141:112658. doi: 10.1016/j.intimp.2024.112658. Epub 2024 Aug 12. Int Immunopharmacol. 2024. PMID: 39137625 Review.
Atopic dermatitis (AD) and psoriasis are chronic skin diseases with a global impact, posing significant challenges to public health systems and severely affecting patients' quality of life. ...We comprehensively assessed the pathogenesis, clinical manifestati
Atopic dermatitis (AD) and psoriasis are chronic skin diseases with a global impact, posing significant challenges to p
Developmental cell programs are co-opted in inflammatory skin disease.
Reynolds G, Vegh P, Fletcher J, Poyner EFM, Stephenson E, Goh I, Botting RA, Huang N, Olabi B, Dubois A, Dixon D, Green K, Maunder D, Engelbert J, Efremova M, Polański K, Jardine L, Jones C, Ness T, Horsfall D, McGrath J, Carey C, Popescu DM, Webb S, Wang XN, Sayer B, Park JE, Negri VA, Belokhvostova D, Lynch MD, McDonald D, Filby A, Hagai T, Meyer KB, Husain A, Coxhead J, Vento-Tormo R, Behjati S, Lisgo S, Villani AC, Bacardit J, Jones PH, O'Toole EA, Ogg GS, Rajan N, Reynolds NJ, Teichmann SA, Watt FM, Haniffa M. Reynolds G, et al. Science. 2021 Jan 22;371(6527):eaba6500. doi: 10.1126/science.aba6500. Science. 2021. PMID: 33479125 Free PMC article.
We profiled the transcriptomes of more than 500,000 single cells from developing human fetal skin, healthy adult skin, and adult skin with atopic dermatitis and psoriasis. We leveraged these datasets to compare cell states across development, homeostasis, and …
We profiled the transcriptomes of more than 500,000 single cells from developing human fetal skin, healthy adult skin, and adult skin with …
Tape strips detect distinct immune and barrier profiles in atopic dermatitis and psoriasis.
He H, Bissonnette R, Wu J, Diaz A, Saint-Cyr Proulx E, Maari C, Jack C, Louis M, Estrada Y, Krueger JG, Zhang N, Pavel AB, Guttman-Yassky E. He H, et al. J Allergy Clin Immunol. 2021 Jan;147(1):199-212. doi: 10.1016/j.jaci.2020.05.048. Epub 2020 Jul 21. J Allergy Clin Immunol. 2021. PMID: 32709423
BACKGROUND: Our current understanding of atopic dermatitis (AD) and psoriasis pathophysiology is largely derived from skin biopsy studies that cause scarring and may be impractical in large-scale clinical trials. ...Terminal differentiation (FLG2 and LCE5A), …
BACKGROUND: Our current understanding of atopic dermatitis (AD) and psoriasis pathophysiology is largely derived from s …
1,258 results