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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 2
1947 4
1948 3
1949 6
1950 5
1951 13
1952 13
1953 11
1954 19
1955 40
1956 82
1957 119
1958 112
1959 104
1960 111
1961 108
1962 143
1963 208
1964 238
1965 179
1966 209
1967 291
1968 385
1969 344
1970 374
1971 450
1972 543
1973 602
1974 598
1975 500
1976 467
1977 418
1978 442
1979 416
1980 439
1981 406
1982 380
1983 344
1984 345
1985 329
1986 422
1987 344
1988 339
1989 370
1990 435
1991 404
1992 346
1993 364
1994 359
1995 347
1996 391
1997 428
1998 442
1999 445
2000 445
2001 458
2002 537
2003 541
2004 552
2005 634
2006 697
2007 738
2008 733
2009 670
2010 739
2011 724
2012 739
2013 667
2014 756
2015 688
2016 694
2017 719
2018 802
2019 778
2020 660
2021 109
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27,435 results
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Psychedelics.
Nichols DE. Nichols DE. Pharmacol Rev. 2016 Apr;68(2):264-355. doi: 10.1124/pr.115.011478. Pharmacol Rev. 2016. PMID: 26841800 Free PMC article. Review.
Psychedelics (serotonergic hallucinogens) are powerful psychoactive substances that alter perception and mood and affect numerous cognitive processes. ...After the virtually contemporaneous discovery of (5R,8R)-(+)-lysergic acid-N,N-diethylamide (LSD)-25 and the ide …
Psychedelics (serotonergic hallucinogens) are powerful psychoactive substances that alter perception and mood and affect numer …
Psychedelics as Medicines: An Emerging New Paradigm.
Nichols DE, Johnson MW, Nichols CD. Nichols DE, et al. Clin Pharmacol Ther. 2017 Feb;101(2):209-219. doi: 10.1002/cpt.557. Epub 2016 Dec 26. Clin Pharmacol Ther. 2017. PMID: 28019026 Review.
Scientific interest in serotonergic psychedelics (e.g., psilocybin and LSD; 5-HT(2A) receptor agonists) has dramatically increased within the last decade. Clinical studies administering psychedelics with psychotherapy have shown preliminary evidence of robust effica …
Scientific interest in serotonergic psychedelics (e.g., psilocybin and LSD; 5-HT(2A) receptor agonists) has dramatically increased wi …
How do psychedelics work?
Carhart-Harris RL. Carhart-Harris RL. Curr Opin Psychiatry. 2019 Jan;32(1):16-21. doi: 10.1097/YCO.0000000000000467. Curr Opin Psychiatry. 2019. PMID: 30394903 Review.
RECENT FINDINGS: This brief opinion piece offers a perspective on how psychedelics work in the brain that may help contextualize these developments. ...The purpose of psychedelic therapy is to harness the opportunity afforded by this belief-relaxation to achieve a h …
RECENT FINDINGS: This brief opinion piece offers a perspective on how psychedelics work in the brain that may help contextualize thes …
Classic psychedelics: An integrative review of epidemiology, therapeutics, mystical experience, and brain network function.
Johnson MW, Hendricks PS, Barrett FS, Griffiths RR. Johnson MW, et al. Pharmacol Ther. 2019 May;197:83-102. doi: 10.1016/j.pharmthera.2018.11.010. Epub 2018 Dec 4. Pharmacol Ther. 2019. PMID: 30521880 Review.
The purpose of this paper is to provide an integrative review and offer novel insights regarding human research with classic psychedelics (classic hallucinogens), which are serotonin 2A receptor (5-HT(2A)R) agonists such as lysergic acid diethylamide (LSD), mescalin …
The purpose of this paper is to provide an integrative review and offer novel insights regarding human research with classic psychedelics …
Psychedelics and Psychedelic-Assisted Psychotherapy.
Reiff CM, Richman EE, Nemeroff CB, Carpenter LL, Widge AS, Rodriguez CI, Kalin NH, McDonald WM; the Work Group on Biomarkers and Novel Treatments, a Division of the American Psychiatric Association Council of Research. Reiff CM, et al. Am J Psychiatry. 2020 May 1;177(5):391-410. doi: 10.1176/appi.ajp.2019.19010035. Epub 2020 Feb 26. Am J Psychiatry. 2020. PMID: 32098487 Review.
OBJECTIVE: The authors provide an evidenced-based summary of the literature on the clinical application of psychedelic drugs in psychiatric disorders. METHODS: Searches of PubMed and PsycINFO via Ovid were conducted for articles in English, in peer-reviewed journals, repor …
OBJECTIVE: The authors provide an evidenced-based summary of the literature on the clinical application of psychedelic drugs in psych …
Return of the psychedelics: Psilocybin for treatment resistant depression.
Patra S. Patra S. Asian J Psychiatr. 2016 Dec;24:51-52. doi: 10.1016/j.ajp.2016.08.010. Epub 2016 Aug 23. Asian J Psychiatr. 2016. PMID: 27931907 Review.
Psilocybin, the clinically most researched classic psychedelic has recently been tested for its safety and efficacy in a clinical population of treatment resistant depression. ...Mechanism of action of psilocybin and efficacy in treatment resistant depression are discussed …
Psilocybin, the clinically most researched classic psychedelic has recently been tested for its safety and efficacy in a clinical pop …
Taking Psychedelics Seriously.
Byock I. Byock I. J Palliat Med. 2018 Apr;21(4):417-421. doi: 10.1089/jpm.2017.0684. Epub 2018 Jan 22. J Palliat Med. 2018. PMID: 29356590 Free PMC article. Review.
BACKGROUND: Psychiatric research in the 1950s and 1960s showed potential for psychedelic medications to markedly alleviate depression and suffering associated with terminal illness. ...Given the prevalence of persistent suffering and growing acceptance of physician-hastene …
BACKGROUND: Psychiatric research in the 1950s and 1960s showed potential for psychedelic medications to markedly alleviate depression …
Psychedelics and music: neuroscience and therapeutic implications.
Barrett FS, Preller KH, Kaelen M. Barrett FS, et al. Int Rev Psychiatry. 2018 Aug;30(4):350-362. doi: 10.1080/09540261.2018.1484342. Epub 2018 Sep 21. Int Rev Psychiatry. 2018. PMID: 30240282 Review.
From the beginning of therapeutic research with psychedelics, music listening has been consistently used as a method to guide or support therapeutic experiences during the acute effects of psychedelic drugs. Recent findings point to the potential of music to support …
From the beginning of therapeutic research with psychedelics, music listening has been consistently used as a method to guide or supp …
Dreams and Psychedelics: Neurophenomenological Comparison and Therapeutic Implications.
Kraehenmann R. Kraehenmann R. Curr Neuropharmacol. 2017;15(7):1032-1042. doi: 10.2174/1573413713666170619092629. Curr Neuropharmacol. 2017. PMID: 28625125 Free PMC article. Review.
The aim of this review is to introduce readers to the similarities and dissimilarities between psychedelic states and night dreams, and to draw conclusions related to therapeutic applications of psychedelics in psychiatry. ...CONCLUSION: The broad overlap between dr …
The aim of this review is to introduce readers to the similarities and dissimilarities between psychedelic states and night dreams, a …
Classical psychedelics for the treatment of depression and anxiety: A systematic review.
Muttoni S, Ardissino M, John C. Muttoni S, et al. J Affect Disord. 2019 Nov 1;258:11-24. doi: 10.1016/j.jad.2019.07.076. Epub 2019 Jul 30. J Affect Disord. 2019. PMID: 31382100
Pharmacological and psychosocial interventions are used to manage these conditions, but their efficacy is limited. Recent interest into the use of psychedelic-assisted therapy using ayahuasca, psilocybin or lysergic acid diethylamide (LSD) may be a promising alternative fo …
Pharmacological and psychosocial interventions are used to manage these conditions, but their efficacy is limited. Recent interest into the …
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