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Pterostilbene alleviated NAFLD via AMPK/mTOR signaling pathways and autophagy by promoting Nrf2.
Shen B, Wang Y, Cheng J, Peng Y, Zhang Q, Li Z, Zhao L, Deng X, Feng H. Shen B, et al. Phytomedicine. 2023 Jan;109:154561. doi: 10.1016/j.phymed.2022.154561. Epub 2022 Nov 21. Phytomedicine. 2023. PMID: 36610156
Autophagy can degrade metabolic waste and accumulated toxic endogenous substances. Pterostilbene (PTE) is an active compound extracted from blueberry, and grape, that exhibits many biological effects, such as antiinflammation and antitumor. ...
Autophagy can degrade metabolic waste and accumulated toxic endogenous substances. Pterostilbene (PTE) is an active compound extracte …
The in vitro and in vivo depigmenting activity of pterostilbene through induction of autophagy in melanocytes and inhibition of UVA-irradiated alpha-MSH in keratinocytes via Nrf2-mediated antioxidant pathways.
Hseu YC, Vudhya Gowrisankar Y, Wang LW, Zhang YZ, Chen XZ, Huang PJ, Yen HR, Yang HL. Hseu YC, et al. Redox Biol. 2021 Aug;44:102007. doi: 10.1016/j.redox.2021.102007. Epub 2021 May 19. Redox Biol. 2021. PMID: 34049220 Free PMC article.
Pterostilbene (Pt) is a natural polyphenol found in blueberries and several grape varieties. ...In vivo results also confirmed that Pt-inhibited tyrosinase expression/activity and endogenous pigmentation in the zebrafish model. Therefore, pterostilbene is a p …
Pterostilbene (Pt) is a natural polyphenol found in blueberries and several grape varieties. ...In vivo results also confirmed …
Pterostilbene: a potential therapeutic agent for fibrotic diseases.
Wang W, Li K, Bai D, Wu J, Xiao W. Wang W, et al. Inflammopharmacology. 2024 Apr;32(2):975-989. doi: 10.1007/s10787-024-01440-z. Epub 2024 Mar 1. Inflammopharmacology. 2024. PMID: 38429613 Review.
This condition is primarily identified by the transformation of fibroblasts into myofibroblasts and the overproduction of extracellular matrix (ECM) by myofibroblasts. Pterostilbene (PTS) is a natural analogue of resveratrol and is most commonly found in blueberries …
This condition is primarily identified by the transformation of fibroblasts into myofibroblasts and the overproduction of extracellular matr …
Two-Stage Regulation of trans-Pterostilbene Biosynthesis in Blueberry Leaf-Derived Cell Cultures.
Kim TE, Pyee J. Kim TE, et al. ACS Omega. 2025 Nov 4;10(45):54167-54174. doi: 10.1021/acsomega.5c06116. eCollection 2025 Nov 18. ACS Omega. 2025. PMID: 41280866 Free PMC article.
Trans-pterostilbene (t-Pt), a methylated derivative of trans-resveratrol (t-R), exhibits potent pharmacological properties but accumulates minimally in plants, limiting its practical applications. This study establishes a proof-of-concept in vitro system for t-Pt pr …
Trans-pterostilbene (t-Pt), a methylated derivative of trans-resveratrol (t-R), exhibits potent pharmacological properties but accumu …
Pterostilbene and cancer: current review.
McCormack D, McFadden D. McCormack D, et al. J Surg Res. 2012 Apr;173(2):e53-61. doi: 10.1016/j.jss.2011.09.054. Epub 2011 Oct 21. J Surg Res. 2012. PMID: 22099605 Review.
Pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene) is an antioxidant that is primarily found in blueberries. ...Additionally, preliminary studies show that pterostilbene exhibits much greater bioavailability compared with other stilbene compounds; however …
Pterostilbene (trans-3,5-dimethoxy-4-hydroxystilbene) is an antioxidant that is primarily found in blueberries. ...Additionall …
Blueberry Component Pterostilbene Protects Corneal Epithelial Cells from Inflammation via Anti-oxidative Pathway.
Li J, Ruzhi Deng, Hua X, Zhang L, Lu F, Coursey TG, Pflugfelder SC, Li DQ. Li J, et al. Sci Rep. 2016 Jan 14;6:19408. doi: 10.1038/srep19408. Sci Rep. 2016. PMID: 26762881 Free PMC article.
Blueberries have been recognized to possess protective properties from inflammation and various diseases, but not for eye and ocular disorders. This study explores potential benefits of pterostilbene (PS), a natural component of blueberries, in preventing ocu …
Blueberries have been recognized to possess protective properties from inflammation and various diseases, but not for eye and ocular …
The blueberry component pterostilbene has potent anti-myeloma activity in bortezomib-resistant cells.
Chen G, Xu Z, Chang G, Hou J, Hu L, Zhang Y, Yu D, Li B, Chang S, Xie Y, Zhang Y, Wei R, Wu H, Xiao W, Sun X, Tao Y, Gao L, Dai B, Shi J, Zhu W. Chen G, et al. Oncol Rep. 2017 Jul;38(1):488-496. doi: 10.3892/or.2017.5675. Epub 2017 May 30. Oncol Rep. 2017. PMID: 28560392
Multiple myeloma (MM) is an incurable hematologic malignancy because of its drug resistance. Pterostilbene (Pter) is found mainly in blueberries and grapes. The effects of Pter and its exact pharmacologic mechanisms on chemoresistant myeloma are not known. ...
Multiple myeloma (MM) is an incurable hematologic malignancy because of its drug resistance. Pterostilbene (Pter) is found mainly in …
Effect of resveratrol and pterostilbene on aging and longevity.
Li YR, Li S, Lin CC. Li YR, et al. Biofactors. 2018 Jan;44(1):69-82. doi: 10.1002/biof.1400. Epub 2017 Dec 6. Biofactors. 2018. PMID: 29210129 Review.
In this review, we discuss the relationship between resveratrol and pterostilbene and possible aging biomarker, including oxidative stress, inflammation, and high-calorie diets. Moreover, we also discuss the positive effect of resveratrol and pterostilbene on lifesp …
In this review, we discuss the relationship between resveratrol and pterostilbene and possible aging biomarker, including oxidative s …
Pterostilbene mitigates scopolamine-induced cognitive impairment by modulating cholinergic pathway and reducing neuroinflammation.
Wang C, Chen L, Wen R, Peng L, Chen C, Zhuo R, Zhao Y, Qiu Y, Yang L, Zhou Y. Wang C, et al. Phytomedicine. 2026 Jan;150:157630. doi: 10.1016/j.phymed.2025.157630. Epub 2025 Dec 1. Phytomedicine. 2026. PMID: 41353883
While current therapies (eg., donepezil) target single pathways (eg., cholinergic), Pterostilbene (Pte), a natural compound from blueberries and traditional medicine offers unexplored potential for multi-target intervention. ...
While current therapies (eg., donepezil) target single pathways (eg., cholinergic), Pterostilbene (Pte), a natural compound from b …
Effects of Pterostilbene on Cardiovascular Health and Disease.
Tian R, Miao L, Cheang WS. Tian R, et al. Curr Issues Mol Biol. 2024 Aug 30;46(9):9576-9587. doi: 10.3390/cimb46090569. Curr Issues Mol Biol. 2024. PMID: 39329921 Free PMC article. Review.
Pterostilbene is a phenolic compound commonly found in blueberries, peanuts, grapes, and other plants. ...Cardiovascular disease is closely related to pathological processes such as inflammation and oxidative stress, which aligns well with the treatment appli …
Pterostilbene is a phenolic compound commonly found in blueberries, peanuts, grapes, and other plants. ...Cardiovascula …
115 results