Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 1
1999 1
2000 2
2001 2
2002 1
2003 2
2004 2
2005 4
2006 4
2007 6
2008 6
2009 4
2010 3
2011 7
2012 9
2013 15
2014 13
2015 14
2016 16
2017 18
2018 12
2019 16
2020 27
2021 33
2022 38
2023 35
2024 32
2025 32
2026 23

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

340 results

Results by year

Filters applied: . Clear all
Page 1
Punicalagin attenuates hyperuricemia via restoring hyperuricemia-induced renal and intestinal dysfunctions.
Han QQ, Ren QD, Guo X, Farag MA, Zhang YH, Zhang MQ, Chen YY, Sun ST, Sun JY, Li NY, Liu C. Han QQ, et al. J Adv Res. 2025 Mar;69:449-461. doi: 10.1016/j.jare.2024.03.029. Epub 2024 Apr 10. J Adv Res. 2025. PMID: 38609050 Free PMC article.
The two main organs in charge of excreting UA are the kidney (70%) and intestine (30%). Previous studies have reported that punicalagin (PU) could protect against kidney and intestinal damages, which makes it a potential candidate for alleviating hyperuricemia. ...
The two main organs in charge of excreting UA are the kidney (70%) and intestine (30%). Previous studies have reported that punicalagin …
Pomegranate.
[No authors listed] [No authors listed] 2023 Sep 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2023 Sep 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 37748009 Free Books & Documents. Review.
Pomegranate juice contains ellagitannins and numerous polyphenols such as delphinidin, cyanidin, pelargonidin, punicalin, pedunculagin, punicalagin, gallagic, and ellagic acid as well as vitamin C and B vitamins. Administration of pomegranate juice to nursing mothers resul …
Pomegranate juice contains ellagitannins and numerous polyphenols such as delphinidin, cyanidin, pelargonidin, punicalin, pedunculagin, p …
Punicalagin Protects Ram Sperm from Oxidative Stress by Enhancing Antioxidant Capacity and Mitochondrial Potential during Liquid Storage at 4 C.
Zhang L, Wang X, Sohail T, Jiang C, Sun Y, Wang J, Sun X, Li Y. Zhang L, et al. Animals (Basel). 2024 Jan 19;14(2):318. doi: 10.3390/ani14020318. Animals (Basel). 2024. PMID: 38275778 Free PMC article.
The aim of this study was to investigate the effect of punicalagin, an antioxidant, on ram sperm quality. Semen samples were collected and pooled from five rams, then diluted using a Tris-based diluent containing various concentrations (0, 5, 15, 30 and 45 muM) of …
The aim of this study was to investigate the effect of punicalagin, an antioxidant, on ram sperm quality. Semen samples were c …
Punicalagin Protects against Diabetic Liver Injury by Upregulating Mitophagy and Antioxidant Enzyme Activities.
Zhang Y, Tan X, Cao Y, An X, Chen J, Yang L. Zhang Y, et al. Nutrients. 2022 Jul 6;14(14):2782. doi: 10.3390/nu14142782. Nutrients. 2022. PMID: 35889739 Free PMC article.
Diabetic liver injury has received increasing attention as a serious complication of type 2 diabetes. Punicalagin (PU), a major component of pomegranate polyphenols, has various biological activities such as antioxidant, anti-inflammatory, and lipid metabolism regul …
Diabetic liver injury has received increasing attention as a serious complication of type 2 diabetes. Punicalagin (PU), a major compo …
Pomegranate Ellagitannins.
Heber D. Heber D. In: Benzie IFF, Wachtel-Galor S, editors. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 10. In: Benzie IFF, Wachtel-Galor S, editors. Herbal Medicine: Biomolecular and Clinical Aspects. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 10. PMID: 22593938 Free Books & Documents. Review.
Pomegranates have been shown to contain 124 different phytochemicals, and some of them act in concert to exert antioxidant and anti-inflammatory effects on cancer cells. Ellagitannins are bioactive polyphenols present in pomegranate. Pomegranate juice obtained by squeezing …
Pomegranates have been shown to contain 124 different phytochemicals, and some of them act in concert to exert antioxidant and anti-i …
Physiological and Immune Functions of Punicalagin.
Venusova E, Kolesarova A, Horky P, Slama P. Venusova E, et al. Nutrients. 2021 Jun 23;13(7):2150. doi: 10.3390/nu13072150. Nutrients. 2021. PMID: 34201484 Free PMC article. Review.
Punicalagin (PUN) is an ellagitannin found in the peel of pomegranate (Punica granatum). ...This work describes the source, metabolism, functions and effects of punicalagin, its derivatives and metabolites. Furthermore, its anti-inflammatory and antioxidant e …
Punicalagin (PUN) is an ellagitannin found in the peel of pomegranate (Punica granatum). ...This work describes the source, metabolis …
Punicalagin as a novel selective aryl hydrocarbon receptor (AhR) modulator upregulates AhR expression through the PDK1/p90RSK/AP-1 pathway to promote the anti-inflammatory response and bactericidal activity of macrophages.
Dai W, Yin S, Wang F, Kuang T, Xiao H, Kang W, Yun C, Wang F, Luo L, Ao S, Zhou J, Yang X, Fan C, Li W, He D, Jin H, Tang W, Liu L, Wang R, Liang H, Zhu J. Dai W, et al. Cell Commun Signal. 2024 Oct 3;22(1):473. doi: 10.1186/s12964-024-01847-9. Cell Commun Signal. 2024. PMID: 39363344 Free PMC article.
Aryl hydrocarbon receptor (AhR) plays an important role in inflammation and immunity as a new therapeutic target for infectious disease and sepsis. Punicalagin (PUN) is a Chinese herbal monomer extract of pomegranate peel that has beneficial anti-inflammatory, antioxida …
Aryl hydrocarbon receptor (AhR) plays an important role in inflammation and immunity as a new therapeutic target for infectious disease and …
In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice.
Seeram NP, Adams LS, Henning SM, Niu Y, Zhang Y, Nair MG, Heber D. Seeram NP, et al. J Nutr Biochem. 2005 Jun;16(6):360-7. doi: 10.1016/j.jnutbio.2005.01.006. J Nutr Biochem. 2005. PMID: 15936648 Free article.
Punicalagin is the major antioxidant polyphenol ingredient in PJ. Punicalagin, EA, a standardized total pomegranate tannin (TPT) extract and PJ were evaluated for in vitro antiproliferative, apoptotic and antioxidant activities. ...Punicalagin, …
Punicalagin is the major antioxidant polyphenol ingredient in PJ. Punicalagin, EA, a standardized total pomegranate tan …
Ellagitannin Component Punicalin Ameliorates Cognitive Dysfunction, Oxidative Stress, and Neuroinflammation via the Inhibition of cGAS-STING Signaling in the Brain of an Aging Mouse Model.
Chen P, Zhang Z, Lei J, Zhu J, Liu G. Chen P, et al. Phytother Res. 2024 Dec;38(12):5690-5712. doi: 10.1002/ptr.8343. Epub 2024 Sep 23. Phytother Res. 2024. PMID: 39313488
Punicalin (PUN), an ellagitannin component, exerts anti-inflammatory, antioxidant, and anti-apoptotic effects. This study investigated the beneficial effects of PUN against age-related brain damage in mice and explored the underlying mechanisms. ...In conclusion, PUN impro …
Punicalin (PUN), an ellagitannin component, exerts anti-inflammatory, antioxidant, and anti-apoptotic effects. This study investigate …
Multifaceted Neuroprotective Role of Punicalagin: A Review.
Siddiqui N, Saifi A, Chaudhary A, Tripathi PN, Chaudhary A, Sharma A. Siddiqui N, et al. Neurochem Res. 2024 Jun;49(6):1427-1436. doi: 10.1007/s11064-023-04081-w. Epub 2023 Dec 12. Neurochem Res. 2024. PMID: 38085406 Review.
Herbal medicines which have been used in traditional medicine for millennia to treat various neurological problems are also being investigated and scientifically assessed. Punicalagin is a known polyphenol that has significant antioxidant, anti-inflammatory, anti-vi …
Herbal medicines which have been used in traditional medicine for millennia to treat various neurological problems are also being investigat …
340 results