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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1949 2
1950 1
1951 3
1952 3
1953 3
1954 5
1955 2
1956 5
1958 3
1959 1
1961 1
1962 4
1963 2
1979 1
1984 1
1994 1
1996 3
1997 3
1998 7
1999 9
2000 16
2001 11
2002 14
2003 9
2004 23
2005 15
2006 25
2007 21
2008 25
2009 21
2010 32
2011 20
2012 23
2013 27
2014 29
2015 34
2016 18
2017 24
2018 28
2019 39
2020 28
2021 25
2022 19
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521 results
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Pycnogenol(®) for the treatment of chronic disorders.
Schoonees A, Visser J, Musekiwa A, Volmink J. Schoonees A, et al. Cochrane Database Syst Rev. 2012 Feb 15;(2):CD008294. doi: 10.1002/14651858.CD008294.pub3. Cochrane Database Syst Rev. 2012. PMID: 22336841 Updated. Review.
Pycnogenol() is marketed as a supplement for preventing or treating a wide range of chronic conditions. ...We also contacted the manufacturer of Pycnogenol() and hand-searched bibliographies of included studies. SELECTION CRITERIA: Randomised controlled trials evalu
Pycnogenol() is marketed as a supplement for preventing or treating a wide range of chronic conditions. ...We also contacted the manu
Pycnogenol® Supplementation Prevents Recurrent Urinary Tract Infections/Inflammation and Interstitial Cystitis.
Ledda A, Hu S, Cesarone MR, Belcaro G, Dugall M, Feragalli B, Cotellese R, Hosoi M, Ippolito E, Corsi M, Luzzi R. Ledda A, et al. Evid Based Complement Alternat Med. 2021 Jun 23;2021:9976299. doi: 10.1155/2021/9976299. eCollection 2021. Evid Based Complement Alternat Med. 2021. PMID: 34257695 Free PMC article.

The incidence of UTI symptoms, in comparison with the period before inclusion in the standard management (SM) group, decreased significantly; there was a more pronounced decrease in the rate of recurrent infections in the Pycnogenol group (p < 0.05). The improvement in

The incidence of UTI symptoms, in comparison with the period before inclusion in the standard management (SM) group, decreased significantly …
French Maritime Pine Bark Extract (Pycnogenol®) Effects on Human Skin: Clinical and Molecular Evidence.
Grether-Beck S, Marini A, Jaenicke T, Krutmann J. Grether-Beck S, et al. Skin Pharmacol Physiol. 2016;29(1):13-7. doi: 10.1159/000441039. Epub 2015 Oct 23. Skin Pharmacol Physiol. 2016. PMID: 26492562 Free article. Review.
Within recent years, however, a growing number of studies suggests that the beneficial effects of these products clearly extend beyond photoprotection. In this review we take the nutritional supplement Pycnogenol, which is based on an extract prepared from French marine pi …
Within recent years, however, a growing number of studies suggests that the beneficial effects of these products clearly extend beyond photo …
Projected supportive effects of Pycnogenol in patients suffering from multi-dimensional health impairments after a SARS-CoV2 infection.
Weichmann F, Rohdewald P. Weichmann F, et al. Int J Antimicrob Agents. 2020 Dec;56(6):106191. doi: 10.1016/j.ijantimicag.2020.106191. Epub 2020 Oct 9. Int J Antimicrob Agents. 2020. PMID: 33045354 Free PMC article. Review.
Recent reports of patients who were infected with SARS-CoV2 suggest persistent health problems even months after the initial infection. The French maritime pine bark extract Pycnogenol(R) has demonstrated anti-inflammatory, vascular and endothelium-protective effects in ov …
Recent reports of patients who were infected with SARS-CoV2 suggest persistent health problems even months after the initial infection. The …
Effect of Pycnogenol® on attention-deficit hyperactivity disorder (ADHD): study protocol for a randomised controlled trial.
Verlaet AA, Ceulemans B, Verhelst H, Van West D, De Bruyne T, Pieters L, Savelkoul HF, Hermans N. Verlaet AA, et al. Trials. 2017 Mar 28;18(1):145. doi: 10.1186/s13063-017-1879-6. Trials. 2017. PMID: 28351412 Free PMC article. Clinical Trial.
One small randomised trial in ADHD suggests, despite various limitations, therapeutic benefit from Pycnogenol, a herbal, polyphenol-rich extract. METHODS: This phase III trial is a 10-week, randomised, double-blind, placebo and active treatment controlled multicentre trial …
One small randomised trial in ADHD suggests, despite various limitations, therapeutic benefit from Pycnogenol, a herbal, polyphenol-r …
Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis.
Liu X, Machado GC, Eyles JP, Ravi V, Hunter DJ. Liu X, et al. Br J Sports Med. 2018 Feb;52(3):167-175. doi: 10.1136/bjsports-2016-097333. Epub 2017 Oct 10. Br J Sports Med. 2018. PMID: 29018060 Review.
RESULTS: Of 20 supplements investigated in 69 eligible studies, 7 (collagen hydrolysate, passion fruit peel extract, Curcuma longa extract, Boswellia serrata extract, curcumin, pycnogenol and L-carnitine) demonstrated large (effect size >0.80) and clinically important e …
RESULTS: Of 20 supplements investigated in 69 eligible studies, 7 (collagen hydrolysate, passion fruit peel extract, Curcuma longa extract, …
Treatment of erectile dysfunction with pycnogenol and L-arginine.
Stanislavov R, Nikolova V. Stanislavov R, et al. J Sex Marital Ther. 2003 May-Jun;29(3):207-13. doi: 10.1080/00926230390155104. J Sex Marital Ther. 2003. PMID: 12851125 Clinical Trial.
During the second month, patients were additionally supplemented with 40 mg Pycnogenol two times per day; during the third month, the daily dosage was increased to three 40-mg Pycnogenol tablets. ...We conclude that oral administration of L-arginine in combination w …
During the second month, patients were additionally supplemented with 40 mg Pycnogenol two times per day; during the third month, the …
Pycnogenol® in Metabolic Syndrome and Related Disorders.
Gulati OP. Gulati OP. Phytother Res. 2015 Jul;29(7):949-68. doi: 10.1002/ptr.5341. Epub 2015 May 1. Phytother Res. 2015. PMID: 25931421 Review.
Pycnogenol is a French maritime pine bark extract produced from the outer bark of Pinus pinaster Ait. ...This review highlights the pathophysiology of metabolic syndrome and related clinical research findings on the safety and efficacy of Pycnogenol. The results of
Pycnogenol is a French maritime pine bark extract produced from the outer bark of Pinus pinaster Ait. ...This review highlights the p
Primary benign back pain: supplementation with Pycnogenol®.
Cox D, Belcaro G, Cesarone MR, Cotellese R, Dugall M, Feragalli B, Hosoi M, Corsi M, Luzzi R. Cox D, et al. Panminerva Med. 2021 Dec;63(4):472-477. doi: 10.23736/S0031-0808.20.03961-0. Panminerva Med. 2021. PMID: 34915691
No safety problems or tolerability problems were observed with Pycnogenol() or with the SM. The two groups, SM and SM+Pycnogenol(), were comparable at inclusion. ...The decrease in back pain score (VASL score) was faster and more pronounced with Pycnogenol() …
No safety problems or tolerability problems were observed with Pycnogenol() or with the SM. The two groups, SM and SM+Pycnogenol
Pycnogenol® (extract of French maritime pine bark) for the treatment of chronic disorders.
Schoonees A, Visser J, Musekiwa A, Volmink J. Schoonees A, et al. Cochrane Database Syst Rev. 2012 Apr 18;(4):CD008294. doi: 10.1002/14651858.CD008294.pub4. Cochrane Database Syst Rev. 2012. PMID: 22513958 Updated. Review.
Pycnogenol() is marketed as a supplement for preventing or treating a wide range of chronic conditions. ...We also contacted the manufacturer of Pycnogenol() and hand-searched bibliographies of included studies. SELECTION CRITERIA: Randomised controlled trials evalu
Pycnogenol() is marketed as a supplement for preventing or treating a wide range of chronic conditions. ...We also contacted the manu
521 results