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Page 1
Did you mean opyrrolizidine alkaloid (545,936 results)?
Regulatory Perspectives of Pyrrolizidine Alkaloid Contamination in Herbal Medicinal Products.
Wiesner J. Wiesner J. Planta Med. 2022 Feb;88(2):118-124. doi: 10.1055/a-1494-1363. Epub 2021 Jun 24. Planta Med. 2022. PMID: 34169489 Free article. Review.
The toxicity of plants containing certain pyrrolizidine alkaloids has long been recognized in grazing animals and humans. Genotoxicity and carcinogenicity data from in vitro and in vivo (animal) studies were published over the last few decades for some of the 1,2-un …
The toxicity of plants containing certain pyrrolizidine alkaloids has long been recognized in grazing animals and humans. Geno …
Fasting augments pyrrolizidine alkaloid-induced hepatotoxicity.
Ma J, Zhang C, He Y, Chen X, Lin G. Ma J, et al. Arch Toxicol. 2022 Feb;96(2):639-651. doi: 10.1007/s00204-021-03193-y. Epub 2021 Nov 18. Arch Toxicol. 2022. PMID: 34792613
Pyrrolizidine alkaloids (PAs) are phytotoxins widely present in various natural products and foodstuffs. ...
Pyrrolizidine alkaloids (PAs) are phytotoxins widely present in various natural products and foodstuffs. ...
Quinolizidine and Pyrrolizidine Alkaloid Chemical Ecology - a Mini-Review on Their Similarities and Differences.
Wink M. Wink M. J Chem Ecol. 2019 Feb;45(2):109-115. doi: 10.1007/s10886-018-1005-6. Epub 2018 Aug 6. J Chem Ecol. 2019. PMID: 30079442 Review.
This mini-review summarizes over 40 years of research on quinolizidine (QAs) and pyrrolizidine alkaloids (PAs). Emphasis is on the chemical ecology of both groups of alkaloids, which serve as general defense compounds against herbivores for the plants produci …
This mini-review summarizes over 40 years of research on quinolizidine (QAs) and pyrrolizidine alkaloids (PAs). Emphasis is on …
Pyrrolizidine alkaloid biosynthesis, evolution of a pathway in plant secondary metabolism.
Ober D, Kaltenegger E. Ober D, et al. Phytochemistry. 2009 Oct-Nov;70(15-16):1687-95. doi: 10.1016/j.phytochem.2009.05.017. Epub 2009 Jun 21. Phytochemistry. 2009. PMID: 19545881 Review.
The system of pyrrolizidine alkaloids has proven to be a powerful system for studying the evolution of a biosynthetic pathway in plant secondary metabolism. Pyrrolizidine alkaloids are typical plant secondary products produced by the plant as a defense …
The system of pyrrolizidine alkaloids has proven to be a powerful system for studying the evolution of a biosynthetic pathway …
Pyrrole-protein adducts - A biomarker of pyrrolizidine alkaloid-induced hepatotoxicity.
Ma J, Xia Q, Fu PP, Lin G. Ma J, et al. J Food Drug Anal. 2018 Jul;26(3):965-972. doi: 10.1016/j.jfda.2018.05.005. Epub 2018 Jun 14. J Food Drug Anal. 2018. PMID: 29976414 Free PMC article. Review.
Pyrrolizidine alkaloids (PAs) are phytotoxins identified in over 6000 plant species worldwide. ...
Pyrrolizidine alkaloids (PAs) are phytotoxins identified in over 6000 plant species worldwide. ...
Pyrrolizidine Alkaloid-Induced Hepatotoxicity Associated with the Formation of Reactive Metabolite-Derived Pyrrole-Protein Adducts.
Ma J, Li M, Li N, Chan WY, Lin G. Ma J, et al. Toxins (Basel). 2021 Oct 13;13(10):723. doi: 10.3390/toxins13100723. Toxins (Basel). 2021. PMID: 34679016 Free PMC article.
Pyrrolizidine alkaloids (PAs) with 1,2-unsaturated necine base are hepatotoxic phytotoxins. ...
Pyrrolizidine alkaloids (PAs) with 1,2-unsaturated necine base are hepatotoxic phytotoxins. ...
Tu-San-Qi (Gynura japonica): the culprit behind pyrrolizidine alkaloid-induced liver injury in China.
Zhu L, Zhang CY, Li DP, Chen HB, Ma J, Gao H, Ye Y, Wang JY, Fu PP, Lin G. Zhu L, et al. Acta Pharmacol Sin. 2021 Aug;42(8):1212-1222. doi: 10.1038/s41401-020-00553-9. Epub 2020 Nov 5. Acta Pharmacol Sin. 2021. PMID: 33154553 Free PMC article. Review.
Among different hepatotoxic herbs, the pyrrolizidine alkaloid (PA)-producing herb Gynura japonica contributes significantly to HILI by inducing hepatic sinusoidal obstruction syndrome (HSOS), a liver disorder characterized by hepatomegaly, hyperbilirubinemia, and as …
Among different hepatotoxic herbs, the pyrrolizidine alkaloid (PA)-producing herb Gynura japonica contributes significantly to …
New otonecine-type pyrrolizidine alkaloid from Petasites japonicus.
Kitajima M, Okabe K, Yoshida M, Nakabayashi R, Saito K, Kogure N, Takayama H. Kitajima M, et al. J Nat Med. 2019 Jun;73(3):602-607. doi: 10.1007/s11418-019-01285-9. Epub 2019 Feb 19. J Nat Med. 2019. PMID: 30784002
One new otonecine-type pyrrolizidine alkaloid secopetasitenine (1), along with petasitenine (fukinotoxine, 2), neopetasitenine (3), and senkirkine (4), was isolated from the whole plant of Petasites japonicus. The structure of 1 was determined by spectroscopic analy …
One new otonecine-type pyrrolizidine alkaloid secopetasitenine (1), along with petasitenine (fukinotoxine, 2), neopetasitenine …
Expert consensus on the clinical management of pyrrolizidine alkaloid-induced hepatic sinusoidal obstruction syndrome.
Zhuge Y, Liu Y, Xie W, Zou X, Xu J, Wang J; Chinese Society of Gastroenterology Committee of Hepatobiliary Disease. Zhuge Y, et al. J Gastroenterol Hepatol. 2019 Apr;34(4):634-642. doi: 10.1111/jgh.14612. Epub 2019 Feb 21. J Gastroenterol Hepatol. 2019. PMID: 30669184 Review.
In China, this disease is often associated with the oral intake of plants that contain pyrrolidine alkaloids. The existing guidelines are limited to HSOS associated with hematopoietic stem cell transplantation in Western countries. ...
In China, this disease is often associated with the oral intake of plants that contain pyrrolidine alkaloids. The existing guidelines …
4,430 results