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Quo Vadis qNMR?
Diehl B, Holzgrabe U, Monakhova Y, Schönberger T. Diehl B, et al. J Pharm Biomed Anal. 2020 Jan 5;177:112847. doi: 10.1016/j.jpba.2019.112847. Epub 2019 Aug 30. J Pharm Biomed Anal. 2020. PMID: 31505431 Review.
Mixtures can be characterized much better by applying various chemometric methods and separating the signals of mixture components can be achieved by DOSY experiments. All these methods contribute to the platform of qNMR methods and extend the possibilities of NMR for quan …
Mixtures can be characterized much better by applying various chemometric methods and separating the signals of mixture components can be ac …
The qNMR Summit 5.0: Proceedings and Status of qNMR Technology.
Giancaspro G, Adams KM, Bhavaraju S, Corbett C, Diehl B, Freudenberger JC, Fritsch K, Krishnamurthy K, Laatikainen P, Martos G, Miura T, Nam JW, Niemitz M, Nishizaki Y, Sugimoto N, Obkircher M, Phansalkar R, Ray GJ, Saito T, Sørensen D, Urbas A, Napolitano JG, Tadjimukhamedov F, Bzhelyansky A, Liu Y, Pauli GF. Giancaspro G, et al. Anal Chem. 2021 Sep 14;93(36):12162-12169. doi: 10.1021/acs.analchem.1c02056. Epub 2021 Sep 2. Anal Chem. 2021. PMID: 34473490 Free article. Review.
The goal of the qNMR Summit is to take stock of the status quo and the recent developments in qNMR research and applications in a timely and accurate manner. It provides a platform for both advanced and novice qNMR practitioners to receive a well-rounded upda …
The goal of the qNMR Summit is to take stock of the status quo and the recent developments in qNMR research and applications i …
Quantitative NMR (qNMR) for pharmaceutical analysis: The pioneering work of George Hanna at the US FDA.
Jaki BU, Bzhelyansky A, Pauli GF. Jaki BU, et al. Magn Reson Chem. 2021 Jan;59(1):7-15. doi: 10.1002/mrc.5099. Epub 2020 Oct 13. Magn Reson Chem. 2021. PMID: 32910504 Review.
In the last two decades, quantitative NMR (qNMR) has become increasingly important for the analysis of pharmaceuticals, chemicals, and natural products including dietary supplements. ...His work has the potential to inspire new developments in qNMR applied to small …
In the last two decades, quantitative NMR (qNMR) has become increasingly important for the analysis of pharmaceuticals, chemicals, an …
Enzyme kinetics by real-time quantitative NMR (qNMR) spectroscopy with progress curve analysis.
Vang JY, Breceda C Jr, Her C, Krishnan VV. Vang JY, et al. Anal Biochem. 2022 Dec 1;658:114919. doi: 10.1016/j.ab.2022.114919. Epub 2022 Sep 22. Anal Biochem. 2022. PMID: 36154835 Free article. Review.
This review article summarizes how the experimental data obtained using quantitative nuclear magnetic resonance (qNMR) spectroscopy can be combined with progress curve analysis to determine enzyme kinetic parameters. The qNMR approach enables following the enzymatic …
This review article summarizes how the experimental data obtained using quantitative nuclear magnetic resonance (qNMR) spectroscopy c …
The application of qNMR for the determination of rosuvastatin in tablet form.
Dİkmen G, Uslu O. Dİkmen G, et al. Turk J Chem. 2021 Feb 17;45(1):132-142. doi: 10.3906/kim-2007-7. eCollection 2021. Turk J Chem. 2021. PMID: 33679159 Free PMC article.
Moreover, LOD and LOQ values using qNMR method were observed as 0.25 mg/mL and 0.80 mg/mL, respectively. ...It was found that qNMR method is simple, efficient, reliable, and accurate method. ...
Moreover, LOD and LOQ values using qNMR method were observed as 0.25 mg/mL and 0.80 mg/mL, respectively. ...It was found that qNMR
(1)H qNMR-Based Metabolomics Discrimination of Covid-19 Severity.
Correia BSB, Ferreira VG, Piagge PMFD, Almeida MB, Assunção NA, Raimundo JRS, Fonseca FLA, Carrilho E, Cardoso DR. Correia BSB, et al. J Proteome Res. 2022 Jul 1;21(7):1640-1653. doi: 10.1021/acs.jproteome.1c00977. Epub 2022 Jun 8. J Proteome Res. 2022. PMID: 35674498
[~1H-qNMR quantification of total ginsenosides in Shenmai Injection].
Li WZ, Yang JY, Zhao F, Pan JY, Qu HB. Li WZ, et al. Zhongguo Zhong Yao Za Zhi. 2022 Feb;47(3):587-592. doi: 10.19540/j.cnki.cjcmm.20211108.302. Zhongguo Zhong Yao Za Zhi. 2022. PMID: 35178940 Chinese.
A content determination method based on ~1H-qNMR was developed for the determination of total ginsenosides in Shenmai Injection. ...The developed ~1H-qNMR-based method for total ginsenosides is simple in operation, short in analysis time, strong in specificity, inde …
A content determination method based on ~1H-qNMR was developed for the determination of total ginsenosides in Shenmai Injection. ...T …
Quantification of polyols in sugar-free foodstuffs by qNMR.
Scettri A, Schievano E. Scettri A, et al. Food Chem. 2022 Oct 1;390:133125. doi: 10.1016/j.foodchem.2022.133125. Epub 2022 May 2. Food Chem. 2022. PMID: 35569397
We present a qNMR method for the determination of low calories sweeteners (erythritol, mannitol, maltitol, sorbitol, isomalt and xylitol) in sugar-free foodstuff. ...
We present a qNMR method for the determination of low calories sweeteners (erythritol, mannitol, maltitol, sorbitol, isomalt and xyli …
A (19)F-qNMR-Guided Mathematical Model for G Protein-Coupled Receptor Signaling.
Giraldo J, Madsen JJ, Wang X, Wang L, Zhang C, Ye L. Giraldo J, et al. Mol Pharmacol. 2023 Dec 15;105(1):54-62. doi: 10.1124/molpharm.123.000754. Mol Pharmacol. 2023. PMID: 37907352
However, research indicates that a GPCR possesses multiple active-(like) states that can interact with Galphabetagamma independently, regulating varied nucleotide exchanges. With the guide of (19)F-qNMR, the transitions among these states are quantified as a function of li …
However, research indicates that a GPCR possesses multiple active-(like) states that can interact with Galphabetagamma independently, regula …
[Quality evaluation of ginsenoside reference substances based on qNMR spectroscopy].
Pan JY, Zhao F, Li WZ, Qu HB. Pan JY, et al. Zhongguo Zhong Yao Za Zhi. 2022 Feb;47(3):575-580. doi: 10.19540/j.cnki.cjcmm.20211108.304. Zhongguo Zhong Yao Za Zhi. 2022. PMID: 35178938 Chinese.
In conclusion, the qNMR spectroscopy-based method can ensure the quality of ginsenoside reference substances and provide powerful support for the accurate quality evaluation of Chinese medicine and its preparations. The qNMR spectroscopy-based method is simple, rapi …
In conclusion, the qNMR spectroscopy-based method can ensure the quality of ginsenoside reference substances and provide powerful sup …
501 results