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Adeno-associated Virus (AAV) Serotypes Have Distinctive Interactions with Domains of the Cellular AAV Receptor.
Pillay S, Zou W, Cheng F, Puschnik AS, Meyer NL, Ganaie SS, Deng X, Wosen JE, Davulcu O, Yan Z, Engelhardt JF, Brown KE, Chapman MS, Qiu J, Carette JE. Pillay S, et al. Among authors: brown ke, qiu j. J Virol. 2017 Aug 24;91(18):e00391-17. doi: 10.1128/JVI.00391-17. Print 2017 Sep 15. J Virol. 2017. PMID: 28679762 Free PMC article.
Adeno-associated virus (AAV) entry is determined by its interactions with specific surface glycans and a proteinaceous receptor(s). Adeno-associated virus receptor (AAVR) (also named KIAA0319L) is an essential cellular receptor req
Adeno-associated virus (AAV) entry is determined by its interactions with specific surface glycans and a proteinaceous
An Alternate Route for Adeno-associated Virus (AAV) Entry Independent of AAV Receptor.
Dudek AM, Pillay S, Puschnik AS, Nagamine CM, Cheng F, Qiu J, Carette JE, Vandenberghe LH. Dudek AM, et al. Among authors: qiu j. J Virol. 2018 Mar 14;92(7):e02213-17. doi: 10.1128/JVI.02213-17. Print 2018 Apr 1. J Virol. 2018. PMID: 29343568 Free PMC article.
Determinants and mechanisms of cell attachment and entry steer adeno-associated virus (AAV) in its utility as a gene therapy vector. ...This work furthers our understanding of the entry of AAV, a vector system of broad utility in gene therapy.IMPORTANCE Ad
Determinants and mechanisms of cell attachment and entry steer adeno-associated virus (AAV) in its utility as a gene th …
Human Parvoviruses.
Qiu J, Söderlund-Venermo M, Young NS. Qiu J, et al. Clin Microbiol Rev. 2017 Jan;30(1):43-113. doi: 10.1128/CMR.00040-16. Clin Microbiol Rev. 2017. PMID: 27806994 Free PMC article. Review.
Parvovirus B19 (B19V) and human bocavirus 1 (HBoV1), members of the large Parvoviridae family, are human pathogens responsible for a variety of diseases. ...Additional human parvoviruses, including HBoV2 to -4, human parvovirus 4 (PARV4), and human buf
Parvovirus B19 (B19V) and human bocavirus 1 (HBoV1), members of the large Parvoviridae family, are human pathogens responsible
Novel Chimeric Gene Therapy Vectors Based on Adeno-Associated Virus and Four Different Mammalian Bocaviruses.
Fakhiri J, Schneider MA, Puschhof J, Stanifer M, Schildgen V, Holderbach S, Voss Y, El Andari J, Schildgen O, Boulant S, Meister M, Clevers H, Yan Z, Qiu J, Grimm D. Fakhiri J, et al. Among authors: qiu j. Mol Ther Methods Clin Dev. 2019 Jan 18;12:202-222. doi: 10.1016/j.omtm.2019.01.003. eCollection 2019 Mar 15. Mol Ther Methods Clin Dev. 2019. PMID: 30766894 Free PMC article.
Parvoviruses are highly attractive templates for the engineering of safe, efficient, and specific gene therapy vectors, as best exemplified by adeno-associated virus (AAV). Another candidate that currently garners increasing attention is human bocav
Parvoviruses are highly attractive templates for the engineering of safe, efficient, and specific gene therapy vectors, as best exemp
SARS-CoV-2 is an appropriate name for the new coronavirus.
Wu Y, Ho W, Huang Y, Jin DY, Li S, Liu SL, Liu X, Qiu J, Sang Y, Wang Q, Yuen KY, Zheng ZM. Wu Y, et al. Among authors: qiu j. Lancet. 2020 Mar 21;395(10228):949-950. doi: 10.1016/S0140-6736(20)30557-2. Epub 2020 Mar 6. Lancet. 2020. PMID: 32151324 Free PMC article. No abstract available.
Recent Advances in Replication and Infection of Human Parvovirus B19.
Ganaie SS, Qiu J. Ganaie SS, et al. Among authors: qiu j. Front Cell Infect Microbiol. 2018 Jun 5;8:166. doi: 10.3389/fcimb.2018.00166. eCollection 2018. Front Cell Infect Microbiol. 2018. PMID: 29922597 Free PMC article. Review.
The exclusive restriction of B19V replication to erythroid lineage cells is partly due to the expression of receptor and co-receptor(s) on the cell surface of human EPCs and partly depends on the intracellular factors essential for virus replication. ...We discuss t …
The exclusive restriction of B19V replication to erythroid lineage cells is partly due to the expression of receptor and co-receptor(s
Molecular characterization of the small nonstructural proteins of parvovirus Aleutian mink disease virus (AMDV) during infection.
Huang Q, Luo Y, Cheng F, Best SM, Bloom ME, Qiu J. Huang Q, et al. Among authors: qiu j. Virology. 2014 Mar;452-453:23-31. doi: 10.1016/j.virol.2014.01.005. Epub 2014 Jan 28. Virology. 2014. PMID: 24606679 Free PMC article.
Aleutian mink disease virus (AMDV) is the only member in genus Amdovirus of the family Parvoviridae. ...More importantly, we provided evidence that both NS2 and NS3 are necessary for AMDV replication....
Aleutian mink disease virus (AMDV) is the only member in genus Amdovirus of the family Parvoviridae. ...More importantl …
Establishment of a Recombinant AAV2/HBoV1 Vector Production System in Insect Cells.
Deng X, Zou W, Yan Z, Qiu J. Deng X, et al. Among authors: qiu j. Genes (Basel). 2020 Apr 17;11(4):439. doi: 10.3390/genes11040439. Genes (Basel). 2020. PMID: 32316599 Free PMC article.
We have previously developed an rAAV2/HBoV1 vector in which a recombinant adeno-associated virus 2 (rAAV2) genome is pseudopackaged into a human bocavirus 1 (HBoV1) capsid. ...
We have previously developed an rAAV2/HBoV1 vector in which a recombinant adeno-associated virus 2 (rAAV2) genome is ps …
Parvovirus infection-induced DNA damage response.
Luo Y, Qiu J. Luo Y, et al. Among authors: qiu j. Future Virol. 2013 Mar 1;8(3):245-257. doi: 10.2217/fvl.13.5. Future Virol. 2013. PMID: 25429305 Free PMC article.
Parvoviruses are a group of small DNA viruses with ssDNA genomes flanked by two inverted terminal structures. Due to a limited genetic resource they require host cellular factors and sometimes a helper virus for efficient viral replication. Recent studies hav
Parvoviruses are a group of small DNA viruses with ssDNA genomes flanked by two inverted terminal structures. Due to a limited
N6-methyladenosine modification and METTL3 modulate enterovirus 71 replication.
Hao H, Hao S, Chen H, Chen Z, Zhang Y, Wang J, Wang H, Zhang B, Qiu J, Deng F, Guan W. Hao H, et al. Among authors: qiu j. Nucleic Acids Res. 2019 Jan 10;47(1):362-374. doi: 10.1093/nar/gky1007. Nucleic Acids Res. 2019. PMID: 30364964 Free PMC article.
It has been previously reported that viral RNA contains internal m6A modifications; however, only recently the function of m6A modification in viral RNAs has been elucidated during infections of HIV, hepatitis C virus and Zika virus. In the present study, we …
It has been previously reported that viral RNA contains internal m6A modifications; however, only recently the function of m6A modification …
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