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1990 1
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2023 61
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317 results

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Page 1
Quercetin and its derivates as antiviral potentials: A comprehensive review.
Di Petrillo A, Orrù G, Fais A, Fantini MC. Di Petrillo A, et al. Phytother Res. 2022 Jan;36(1):266-278. doi: 10.1002/ptr.7309. Epub 2021 Oct 28. Phytother Res. 2022. PMID: 34709675 Free PMC article. Review.
Quercetin, widely distributed in fruits and vegetables, is a flavonoid known for its antioxidant, antiviral, antimicrobial, and antiinflammatory properties. ...Quercetin could also be useful in combination with other drugs to potentially enhance the effects or syner
Quercetin, widely distributed in fruits and vegetables, is a flavonoid known for its antioxidant, antiviral, antimicrobial, and antii
A role for quercetin in coronavirus disease 2019 (COVID-19).
Derosa G, Maffioli P, D'Angelo A, Di Pierro F. Derosa G, et al. Phytother Res. 2021 Mar;35(3):1230-1236. doi: 10.1002/ptr.6887. Epub 2020 Oct 9. Phytother Res. 2021. PMID: 33034398 Free PMC article. Review.
Quercetin has a theoretical, but significant, capability to interfere with SARS-CoV-2 replication, with the results showing this to be the fifth best compound out of 18 candidates. On the basis of the clinical COVID-19 manifestations, the multifaceted aspect of querceti
Quercetin has a theoretical, but significant, capability to interfere with SARS-CoV-2 replication, with the results showing this to b
Quercetin in the Prevention and Treatment of Coronavirus Infections: A Focus on SARS-CoV-2.
Gasmi A, Mujawdiya PK, Lysiuk R, Shanaida M, Peana M, Gasmi Benahmed A, Beley N, Kovalska N, Bjørklund G. Gasmi A, et al. Pharmaceuticals (Basel). 2022 Aug 25;15(9):1049. doi: 10.3390/ph15091049. Pharmaceuticals (Basel). 2022. PMID: 36145270 Free PMC article. Review.
Amongst natural molecules for COVID-19 treatment, the flavonoid molecule quercetin (QR) is currently considered one of the most promising. QR is an active agent against SARS and MERS due to its antimicrobial, antiviral, anti-inflammatory, antioxidant, and some other benefi …
Amongst natural molecules for COVID-19 treatment, the flavonoid molecule quercetin (QR) is currently considered one of the most promi …
Senolytics reduce coronavirus-related mortality in old mice.
Camell CD, Yousefzadeh MJ, Zhu Y, Prata LGPL, Huggins MA, Pierson M, Zhang L, O'Kelly RD, Pirtskhalava T, Xun P, Ejima K, Xue A, Tripathi U, Espindola-Netto JM, Giorgadze N, Atkinson EJ, Inman CL, Johnson KO, Cholensky SH, Carlson TW, LeBrasseur NK, Khosla S, O'Sullivan MG, Allison DB, Jameson SC, Meves A, Li M, Prakash YS, Chiarella SE, Hamilton SE, Tchkonia T, Niedernhofer LJ, Kirkland JL, Robbins PD. Camell CD, et al. Science. 2021 Jul 16;373(6552):eabe4832. doi: 10.1126/science.abe4832. Epub 2021 Jun 8. Science. 2021. PMID: 34103349 Free PMC article.
The COVID-19 pandemic has revealed the pronounced vulnerability of the elderly and chronically ill to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced morbidity and mortality. Cellular senescence contributes to inflammation, multiple chronic diseases, a …
The COVID-19 pandemic has revealed the pronounced vulnerability of the elderly and chronically ill to severe acute respiratory syndrome c
Flavonoids as Potential Anti-Inflammatory Molecules: A Review.
Al-Khayri JM, Sahana GR, Nagella P, Joseph BV, Alessa FM, Al-Mssallem MQ. Al-Khayri JM, et al. Molecules. 2022 May 2;27(9):2901. doi: 10.3390/molecules27092901. Molecules. 2022. PMID: 35566252 Free PMC article. Review.
They inhibit the secretions of enzymes such as lysozymes and beta-glucuronidase and inhibit the secretion of arachidonic acid, which reduces inflammatory reactions. Flavonoids such as quercetin, genistein, apigenin, kaempferol, and epigallocatechin 3-gallate modulate the e …
They inhibit the secretions of enzymes such as lysozymes and beta-glucuronidase and inhibit the secretion of arachidonic acid, which reduces …
Senolytic drugs: from discovery to translation.
Kirkland JL, Tchkonia T. Kirkland JL, et al. J Intern Med. 2020 Nov;288(5):518-536. doi: 10.1111/joim.13141. Epub 2020 Aug 4. J Intern Med. 2020. PMID: 32686219 Free PMC article. Review.
Senolytics are a class of drugs that selectively clear senescent cells (SC). The first senolytic drugs Dasatinib, Quercetin, Fisetin and Navitoclax were discovered using a hypothesis-driven approach. ...
Senolytics are a class of drugs that selectively clear senescent cells (SC). The first senolytic drugs Dasatinib, Quercetin, Fisetin …
Natural product derived phytochemicals in managing acute lung injury by multiple mechanisms.
He YQ, Zhou CC, Yu LY, Wang L, Deng JL, Tao YL, Zhang F, Chen WS. He YQ, et al. Pharmacol Res. 2021 Jan;163:105224. doi: 10.1016/j.phrs.2020.105224. Epub 2020 Sep 29. Pharmacol Res. 2021. PMID: 33007416 Free PMC article. Review.
With increasing in-depth studies of ALI/ARDS, significant breakthroughs have been made, however, there are still no effective pharmacological therapies for treatment of ALI/ARDS. Especially, the novel coronavirus pneumonia (COVID-19) is ravaging the globe, and causes sever …
With increasing in-depth studies of ALI/ARDS, significant breakthroughs have been made, however, there are still no effective pharmacologica …
Bioactive compounds from Huashi Baidu decoction possess both antiviral and anti-inflammatory effects against COVID-19.
Xu H, Li S, Liu J, Cheng J, Kang L, Li W, Zhong Y, Wei C, Fu L, Qi J, Zhang Y, You M, Zhou Z, Zhang C, Su H, Yao S, Zhou Z, Shi Y, Deng R, Lv Q, Li F, Qi F, Chen J, Zhang S, Ma X, Xu Z, Li S, Xu Y, Peng K, Shi Y, Jiang H, Gao GF, Huang L. Xu H, et al. Proc Natl Acad Sci U S A. 2023 May 2;120(18):e2301775120. doi: 10.1073/pnas.2301775120. Epub 2023 Apr 24. Proc Natl Acad Sci U S A. 2023. PMID: 37094153 Free PMC article.
The coronavirus disease 2019 (COVID-19) pandemic is an ongoing global health concern, and effective antiviral reagents are urgently needed. ...Among the 60 compounds, six compounds (magnolol, glycyrrhisoflavone, licoisoflavone A, emodin, echinatin, and quercetin) we …
The coronavirus disease 2019 (COVID-19) pandemic is an ongoing global health concern, and effective antiviral reagents are urgently n …
Could SARS-CoV-2 Spike Protein Be Responsible for Long-COVID Syndrome?
Theoharides TC. Theoharides TC. Mol Neurobiol. 2022 Mar;59(3):1850-1861. doi: 10.1007/s12035-021-02696-0. Epub 2022 Jan 13. Mol Neurobiol. 2022. PMID: 35028901 Free PMC article. Review.
Hence, there is urgent need to better understand the neurotoxic effects of the spike protein and to consider possible interventions to mitigate spike protein-related detrimental effects to the brain, possibly via use of small natural molecules, especially the flavonoids luteolin …
Hence, there is urgent need to better understand the neurotoxic effects of the spike protein and to consider possible interventions to mitig …
Evaluation of antiviral activities of Houttuynia cordata Thunb. extract, quercetin, quercetrin and cinanserin on murine coronavirus and dengue virus infection.
Chiow KH, Phoon MC, Putti T, Tan BK, Chow VT. Chiow KH, et al. Asian Pac J Trop Med. 2016 Jan;9(1):1-7. doi: 10.1016/j.apjtm.2015.12.002. Epub 2015 Dec 19. Asian Pac J Trop Med. 2016. PMID: 26851778 Free PMC article. Review.
OBJECTIVE: To evaluate the in vitro activities of the ethyl acetate (EA) fraction of Houttuynia cordata (H. cordata) Thunb. (Saururaceae) and three of its constituent flavonoids (quercetin, quercitrin and rutin) against murine coronavirus and dengue virus (DENV). .. …
OBJECTIVE: To evaluate the in vitro activities of the ethyl acetate (EA) fraction of Houttuynia cordata (H. cordata) Thunb. (Saururaceae) an …
317 results