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Year Number of Results
1984 1
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1997 3
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851 results

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Page 1
Quercetin improves vascular endothelial function through promotion of autophagy in hypertensive rats.
Lin X, Han T, Fan Y, Wu S, Wang F, Wang C. Lin X, et al. Life Sci. 2020 Oct 1;258:118106. doi: 10.1016/j.lfs.2020.118106. Epub 2020 Jul 16. Life Sci. 2020. PMID: 32682916
AIMS: Endothelial dysfunction is a hallmark of hypertension. Herein, we assessed the effect of quercetin, a common dietary antioxidant, on endothelial function of spontaneously hypertensive rats (SHRs), and investigated the underlying molecular mechani …
AIMS: Endothelial dysfunction is a hallmark of hypertension. Herein, we assessed the effect of quercetin, a common dietary ant …
Endothelial function and cardiovascular disease: effects of quercetin and wine polyphenols.
Perez-Vizcaino F, Duarte J, Andriantsitohaina R. Perez-Vizcaino F, et al. Free Radic Res. 2006 Oct;40(10):1054-65. doi: 10.1080/10715760600823128. Free Radic Res. 2006. PMID: 17015250 Review.
In the present paper, we review the effects of flavonoids, especially quercetin and wine polyphenols, on endothelial function and dysfunction and its potential protective role in hypertension, ischemic heart disease and stroke. ...Moreover, some clinical stud …
In the present paper, we review the effects of flavonoids, especially quercetin and wine polyphenols, on endothelial functi
The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
Zhu Y, Tchkonia T, Pirtskhalava T, Gower AC, Ding H, Giorgadze N, Palmer AK, Ikeno Y, Hubbard GB, Lenburg M, O'Hara SP, LaRusso NF, Miller JD, Roos CM, Verzosa GC, LeBrasseur NK, Wren JD, Farr JN, Khosla S, Stout MB, McGowan SJ, Fuhrmann-Stroissnigg H, Gurkar AU, Zhao J, Colangelo D, Dorronsoro A, Ling YY, Barghouthy AS, Navarro DC, Sano T, Robbins PD, Niedernhofer LJ, Kirkland JL. Zhu Y, et al. Aging Cell. 2015 Aug;14(4):644-58. doi: 10.1111/acel.12344. Epub 2015 Apr 22. Aging Cell. 2015. PMID: 25754370 Free PMC article.
Dasatinib eliminated senescent human fat cell progenitors, while quercetin was more effective against senescent human endothelial cells and mouse BM-MSCs. The combination of dasatinib and quercetin was effective in eliminating senescent MEFs. In vivo, this co …
Dasatinib eliminated senescent human fat cell progenitors, while quercetin was more effective against senescent human endothelial
Quercetin ameliorates atherosclerosis by inhibiting inflammation of vascular endothelial cells via Piezo1 channels.
Wang YM, Chu TJ, Wan RT, Niu WP, Bian YF, Li J. Wang YM, et al. Phytomedicine. 2024 Sep;132:155865. doi: 10.1016/j.phymed.2024.155865. Epub 2024 Jul 9. Phytomedicine. 2024. PMID: 39004029
BACKGROUND: Natural antioxidants, exemplified by quercetin (Qu), have been shown to exert a protective effect against atherosclerosis (AS). ...METHODS/STUDY DESIGNS: The inflammatory cytokine expression, activity of NLRP3 inflammasome and NF-kappaB, as well as mechanically …
BACKGROUND: Natural antioxidants, exemplified by quercetin (Qu), have been shown to exert a protective effect against atherosclerosis …
Quercetin protects endothelial function from inflammation induced by localized disturbed flow by inhibiting NRP2 -VEGFC complex.
Zhou W, Wang F, Qian X, Luo S, Wang Z, Gao X, Kong X, Zhang J, Chen S. Zhou W, et al. Int Immunopharmacol. 2023 Mar;116:109842. doi: 10.1016/j.intimp.2023.109842. Epub 2023 Feb 8. Int Immunopharmacol. 2023. PMID: 36764279
Atherosclerosis is a focal chronic inflammatory disease, the initial pathogenic event of which is endothelial dysfunction, and disturbed flow (DF) is the primary and vital factor underlying endothelial dysfunction. ...Knockdown of NRP2 in HUVECs significantly amelio …
Atherosclerosis is a focal chronic inflammatory disease, the initial pathogenic event of which is endothelial dysfunction, and distur …
Quercetin Attenuates Vascular Endothelial Dysfunction in Atherosclerotic Mice by Inhibiting Myeloperoxidase and NADPH Oxidase Function.
Li JX, Tian R, Lu N. Li JX, et al. Chem Res Toxicol. 2023 Feb 20;36(2):260-269. doi: 10.1021/acs.chemrestox.2c00334. Epub 2023 Jan 31. Chem Res Toxicol. 2023. PMID: 36719041
Herein, we found that dietary quercetin significantly inhibited vascular endothelial dysfunction and atherosclerosis in apolipoprotein E-deficient (ApoE(-/-)) mice. ...Moreover, quercetin effectively attenuated MPO/H(2)O(2)-mediated HOCl production and toxici …
Herein, we found that dietary quercetin significantly inhibited vascular endothelial dysfunction and atherosclerosis in apolip …
The Effects of Quercetin Supplementation on Blood Pressures and Endothelial Function Among Patients with Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Tamtaji OR, Milajerdi A, Dadgostar E, Kolahdooz F, Chamani M, Amirani E, Mirzaei H, Asemi Z. Tamtaji OR, et al. Curr Pharm Des. 2019;25(12):1372-1384. doi: 10.2174/1381612825666190513095352. Curr Pharm Des. 2019. PMID: 31092175
BACKGROUND: This systematic review and meta-analysis of randomized controlled trials (RCTs) were performed to determine the effect of quercetin administration on blood pressures and endothelial function among patients with metabolic syndrome (MetS) and relate …
BACKGROUND: This systematic review and meta-analysis of randomized controlled trials (RCTs) were performed to determine the effect of que
Quercetin ameliorates ox-LDL-induced cellular senescence of aortic endothelial cells and macrophages by p16/p21, p53/SERPINE1, and AMPK/mTOR pathways.
Liang X, Zhang J, Yu J, Zhao J, Yang S. Liang X, et al. Eur J Med Res. 2025 May 3;30(1):359. doi: 10.1186/s40001-025-02562-y. Eur J Med Res. 2025. PMID: 40319296 Free PMC article.
METHODS: Oxidized low-density lipoprotein (ox-LDL)-induced human aortic endothelial cells (HAECs) and mouse RAW264.7 macrophages were established, with quercetin treatment or p16, p21 or SERPINE1 siRNA transfection. ...In AS mouse models, quercetin treatment …
METHODS: Oxidized low-density lipoprotein (ox-LDL)-induced human aortic endothelial cells (HAECs) and mouse RAW264.7 macrophages were …
Quercetin Mitigates Endothelial Activation in a Novel Intestinal-Endothelial-Monocyte/Macrophage Coculture Setup.
Vissenaekens H, Grootaert C, Raes K, De Munck J, Smagghe G, Boon N, Van Camp J. Vissenaekens H, et al. Inflammation. 2022 Aug;45(4):1600-1611. doi: 10.1007/s10753-022-01645-w. Epub 2022 Mar 30. Inflammation. 2022. PMID: 35352237
Atherosclerosis initiation is associated with a pro-inflammatory state of the endothelium. Quercetin is a flavonoid abundantly present in plant-based foods, with a possible impact on cardiovascular health. In this study, the effects of quercetin on lipopolysa …
Atherosclerosis initiation is associated with a pro-inflammatory state of the endothelium. Quercetin is a flavonoid abundantly …
Mechanism of Bazhen decoction in the treatment of colorectal cancer based on network pharmacology, molecular docking, and experimental validation.
Lu S, Sun X, Zhou Z, Tang H, Xiao R, Lv Q, Wang B, Qu J, Yu J, Sun F, Deng Z, Tian Y, Li C, Yang Z, Yang P, Rao B. Lu S, et al. Front Immunol. 2023 Sep 20;14:1235575. doi: 10.3389/fimmu.2023.1235575. eCollection 2023. Front Immunol. 2023. PMID: 37799727 Free PMC article.
Furthermore, BZD has the potential to downregulate the PD-1 expression on T cell surfaces, indicating its ability to effectively restore T cell function by inhibiting immune checkpoints. The results of HE staining suggest that BZD exhibits favorable safety profiles. ...Fur …
Furthermore, BZD has the potential to downregulate the PD-1 expression on T cell surfaces, indicating its ability to effectively restore T c …
851 results