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Improving quercetin bioavailability: A systematic review and meta-analysis of human intervention studies.
Liu L, Barber E, Kellow NJ, Williamson G. Liu L, et al. Food Chem. 2025 Jun 15;477:143630. doi: 10.1016/j.foodchem.2025.143630. Epub 2025 Feb 26. Food Chem. 2025. PMID: 40037045 Free article.
The bioavailability of quercetin in humans was affected by several factors. 1) Chemical structure: Quercetin-3-O-oligoglucosides exhibited 2-fold higher bioavailability than quercetin-3-O-glucoside, 10-fold higher than quercetin-3-O-rutin …
The bioavailability of quercetin in humans was affected by several factors. 1) Chemical structure: Quercetin-3-O-oligog …
Quercetin Phytosome as a potential candidate for managing COVID-19.
DI Pierro F, Khan A, Bertuccioli A, Maffioli P, Derosa G, Khan S, Khan BA, Nigar R, Ujjan I, Devrajani BR. DI Pierro F, et al. Minerva Gastroenterol (Torino). 2021 Jun;67(2):190-195. doi: 10.23736/S2724-5985.20.02771-3. Epub 2020 Oct 5. Minerva Gastroenterol (Torino). 2021. PMID: 33016666 Free article. Review.
A phospholipid delivery form of quercetin (Quercetin Phytosome( )) has been recently tested in humans to evaluate a possible improvement in oral bioavailability. ...It has been also observed that the presence of specific glucuronidase could yield free …
A phospholipid delivery form of quercetin (Quercetin Phytosome( )) has been recently tested in humans to evaluate a pos …
Effects of repeated oral intake of a quercetin-containing supplement on allergic reaction: a randomized, placebo-controlled, double-blind parallel-group study.
Yamada S, Shirai M, Inaba Y, Takara T. Yamada S, et al. Eur Rev Med Pharmacol Sci. 2022 Jun;26(12):4331-4345. doi: 10.26355/eurrev_202206_29072. Eur Rev Med Pharmacol Sci. 2022. PMID: 35776034 Free article. Clinical Trial.
A new food-grade bioavailable formulation of quercetin, Quercetin phytosome , was used. RESULTS: At 1:4 weeks after the start of the supplement intake, several scores of JRQLQ, including allergic symptoms, such as eye itching, sneezing, nasal discharge …
A new food-grade bioavailable formulation of quercetin, Quercetin phytosome , was used. RESULTS: At 1:4 weeks af …
Improved Oral Absorption of Quercetin from Quercetin Phytosome , a New Delivery System Based on Food Grade Lecithin.
Riva A, Ronchi M, Petrangolini G, Bosisio S, Allegrini P. Riva A, et al. Eur J Drug Metab Pharmacokinet. 2019 Apr;44(2):169-177. doi: 10.1007/s13318-018-0517-3. Eur J Drug Metab Pharmacokinet. 2019. PMID: 30328058 Free PMC article. Clinical Trial.
Twelve healthy volunteers of both sexes with an age range of 18-50 years were recruited; one dose of quercetin and two different doses of Quercetin Phytosome were administered orally as film-coated tablets. ...These results suggest that Quercetin Ph
Twelve healthy volunteers of both sexes with an age range of 18-50 years were recruited; one dose of quercetin and two different dose …
Enhanced therapeutic benefit of quercetin-loaded phytosome nanoparticles in ovariectomized rats.
Abd El-Fattah AI, Fathy MM, Ali ZY, El-Garawany AEA, Mohamed EK. Abd El-Fattah AI, et al. Chem Biol Interact. 2017 Jun 1;271:30-38. doi: 10.1016/j.cbi.2017.04.026. Epub 2017 Apr 29. Chem Biol Interact. 2017. PMID: 28460884
Quercetin, a dietary flavonol phytoestrogen, has many health benefits but it is poorly absorbed when administered orally. To improve its bioavailability, we prepared quercetin-loaded phytosome nanoparticles (QP) using the thin film hydration method. ..
Quercetin, a dietary flavonol phytoestrogen, has many health benefits but it is poorly absorbed when administered orally. To improve
Nano Drug Delivery Strategies for an Oral Bioenhanced Quercetin Formulation.
Attar ES, Chaudhari VH, Deokar CG, Dyawanapelly S, Devarajan PV. Attar ES, et al. Eur J Drug Metab Pharmacokinet. 2023 Sep;48(5):495-514. doi: 10.1007/s13318-023-00843-7. Epub 2023 Jul 31. Eur J Drug Metab Pharmacokinet. 2023. PMID: 37523008 Review.
However, the oral use of quercetin is limited due to its poor water solubility, low bioavailability, rapid metabolism, and rapid plasma clearance. Quercetin has been studied extensively when used with various nanodelivery systems for enhancing quercetin
However, the oral use of quercetin is limited due to its poor water solubility, low bioavailability, rapid metabolism, and rap …
Novel Nanotechnological Strategies for Skin Anti-aging.
Pozos-Nonato S, Domínguez-Delgado CL, Campos-Santander KA, Benavides AA, Pacheco-Ortin SM, Higuera-Piedrahita RI, Resendiz-González G, Molina-Trinidad EM. Pozos-Nonato S, et al. Curr Pharm Biotechnol. 2023;24(11):1397-1419. doi: 10.2174/1389201024666221223095315. Curr Pharm Biotechnol. 2023. PMID: 36567280 Review.
RESULTS AND DISCUSSION: Results show an enhanced skin anti-aging effect of actives-loaded nanoparticles of next generation (nanostructured lipid carriers, fullerenes, transfersomes, protransfersomes, niosomes, ethosomes, transethosomes, glycerosomes, phytosomes) compared w …
RESULTS AND DISCUSSION: Results show an enhanced skin anti-aging effect of actives-loaded nanoparticles of next generation (nanostructured l …
Quercetin for the treatment of COVID-19 patients: A systematic review and meta-analysis.
Cheema HA, Sohail A, Fatima A, Shahid A, Shahzil M, Ur Rehman ME, Awan RU, Chinnam S, Nashwan AJ. Cheema HA, et al. Rev Med Virol. 2023 Mar;33(2):e2427. doi: 10.1002/rmv.2427. Epub 2023 Feb 13. Rev Med Virol. 2023. PMID: 36779438
Quercetin is a cheap and easily accessible therapeutic option for COVID-19 patients. However, it has not been evaluated in a systematic review until now. ...Quercetin may be of benefit in COVID-19 patients, especially if administered in its phytosome formulat
Quercetin is a cheap and easily accessible therapeutic option for COVID-19 patients. However, it has not been evaluated in a systemat
Polyphenolic phytosomes for targeted drug delivery.
Khabarov IA, Sergazy SD, Amanzhan A, Maikenova AS, Zhabayeva AN, Adekenov SM. Khabarov IA, et al. Fitoterapia. 2025 Dec;187:106920. doi: 10.1016/j.fitote.2025.106920. Epub 2025 Oct 3. Fitoterapia. 2025. PMID: 41046876 Review.
Polyphenolic compounds, such as silybin, curcumin, quercetin, epigallocatechin gallate (EGCG), and grape seed proanthocyanidins, have been successfully formulated into phytosomes, resulting in a significant enhancement of oral bioavailability and therapeutic …
Polyphenolic compounds, such as silybin, curcumin, quercetin, epigallocatechin gallate (EGCG), and grape seed proanthocyanidins, have …
Novel Nanoformulations to Overcome Obstacles in Herbal Drug Delivery for Alzheimer's Disease.
Kumar D, Wal P, Wal A, Lari MQ, Ashesh AM, Kumar D, Singh SK, Singh B, Kumar A. Kumar D, et al. Curr Top Med Chem. 2025;25(28):3234-3250. doi: 10.2174/0115680266362594250527112018. Curr Top Med Chem. 2025. PMID: 40589006 Review.
RESULTS: Curcumin, Centella asiatica, thymoquinone, Hypericum perforatum, Panax ginseng, quercetin, piperine, and a variety of other herbs and herbal medicines have all been examined for their potential to aid in the treatment of brain disorders like Alzheimer's disease. T …
RESULTS: Curcumin, Centella asiatica, thymoquinone, Hypericum perforatum, Panax ginseng, quercetin, piperine, and a variety of other …
18 results