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Year Number of Results
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308 results

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Page 1
Quercetin and its derivates as antiviral potentials: A comprehensive review.
Di Petrillo A, Orrù G, Fais A, Fantini MC. Di Petrillo A, et al. Phytother Res. 2022 Jan;36(1):266-278. doi: 10.1002/ptr.7309. Epub 2021 Oct 28. Phytother Res. 2022. PMID: 34709675 Free PMC article. Review.
Quercetin, widely distributed in fruits and vegetables, is a flavonoid known for its antioxidant, antiviral, antimicrobial, and antiinflammatory properties. Several studies highlight the potential use of quercetin as an antiviral, due to its ability to inhibit the i
Quercetin, widely distributed in fruits and vegetables, is a flavonoid known for its antioxidant, antiviral, antimicrobial, and antii
Senolytic drugs: from discovery to translation.
Kirkland JL, Tchkonia T. Kirkland JL, et al. J Intern Med. 2020 Nov;288(5):518-536. doi: 10.1111/joim.13141. Epub 2020 Aug 4. J Intern Med. 2020. PMID: 32686219 Free PMC article. Review.
Senolytics are a class of drugs that selectively clear senescent cells (SC). The first senolytic drugs Dasatinib, Quercetin, Fisetin and Navitoclax were discovered using a hypothesis-driven approach. SC accumulate with ageing and at causal sites of multiple chronic disorde …
Senolytics are a class of drugs that selectively clear senescent cells (SC). The first senolytic drugs Dasatinib, Quercetin, Fisetin …
Quercetin as a Natural Therapeutic Candidate for the Treatment of Influenza Virus.
Mehrbod P, Hudy D, Shyntum D, Markowski J, Łos MJ, Ghavami S. Mehrbod P, et al. Biomolecules. 2020 Dec 24;11(1):10. doi: 10.3390/biom11010010. Biomolecules. 2020. PMID: 33374214 Free PMC article. Review.
Plant materials and active compounds have been tested for many years, including, more recently, active compounds like flavonoids. Quercetin is a compound belonging to the flavonols class and has shown therapeutic effects against influenza virus. The focus of this re …
Plant materials and active compounds have been tested for many years, including, more recently, active compounds like flavonoids. Quercet
Virus-induced senescence is a driver and therapeutic target in COVID-19.
Lee S, Yu Y, Trimpert J, Benthani F, Mairhofer M, Richter-Pechanska P, Wyler E, Belenki D, Kaltenbrunner S, Pammer M, Kausche L, Firsching TC, Dietert K, Schotsaert M, Martínez-Romero C, Singh G, Kunz S, Niemeyer D, Ghanem R, Salzer HJF, Paar C, Mülleder M, Uccellini M, Michaelis EG, Khan A, Lau A, Schönlein M, Habringer A, Tomasits J, Adler JM, Kimeswenger S, Gruber AD, Hoetzenecker W, Steinkellner H, Purfürst B, Motz R, Di Pierro F, Lamprecht B, Osterrieder N, Landthaler M, Drosten C, García-Sastre A, Langer R, Ralser M, Eils R, Reimann M, Fan DNY, Schmitt CA. Lee S, et al. Nature. 2021 Nov;599(7884):283-289. doi: 10.1038/s41586-021-03995-1. Epub 2021 Sep 13. Nature. 2021. PMID: 34517409
Here we show that SARS-CoV-2, like other viruses, evokes cellular senescence as a primary stress response in infected cells. Virus-induced senescence (VIS) is indistinguishable from other forms of cellular senescence and is accompanied by a senescence-associated sec …
Here we show that SARS-CoV-2, like other viruses, evokes cellular senescence as a primary stress response in infected cells. Virus
Quercetin as an antiviral agent inhibits the Pseudorabies virus in vitro and in vivo.
Sun Y, Li C, Li Z, Shangguan A, Jiang J, Zeng W, Zhang S, He Q. Sun Y, et al. Virus Res. 2021 Nov;305:198556. doi: 10.1016/j.virusres.2021.198556. Epub 2021 Sep 4. Virus Res. 2021. PMID: 34492238
This anti-PRV activity of quercetin was found to be dose-dependent. Furthermore, quercetin also inhibited a wide the infections by a spectrum of PRV strains like HNX, Ea, Bartha and Fa strain. These virucidal effects of quercetin suggest the interaction betwe …
This anti-PRV activity of quercetin was found to be dose-dependent. Furthermore, quercetin also inhibited a wide the infection …
Quercetin pentaacetate inhibits in vitro human respiratory syncytial virus adhesion.
Lopes BRP, da Costa MF, Genova Ribeiro A, da Silva TF, Lima CS, Caruso IP, de Araujo GC, Kubo LH, Iacovelli F, Falconi M, Desideri A, de Oliveira J, Regasini LO, de Souza FP, Toledo KA. Lopes BRP, et al. Virus Res. 2020 Jan 15;276:197805. doi: 10.1016/j.virusres.2019.197805. Epub 2019 Nov 9. Virus Res. 2020. PMID: 31712123 Free article.
Some works criticize the pharmacological use of Quercetin because it has low solubility and low specificity. In this sense, we acetylated Quercetin structure and we used in vitro and in silico assays to compare anti-hRSV function between Quercetin (Q0) and it …
Some works criticize the pharmacological use of Quercetin because it has low solubility and low specificity. In this sense, we acetyl …
Senolytics reduce coronavirus-related mortality in old mice.
Camell CD, Yousefzadeh MJ, Zhu Y, Prata LGPL, Huggins MA, Pierson M, Zhang L, O'Kelly RD, Pirtskhalava T, Xun P, Ejima K, Xue A, Tripathi U, Espindola-Netto JM, Giorgadze N, Atkinson EJ, Inman CL, Johnson KO, Cholensky SH, Carlson TW, LeBrasseur NK, Khosla S, O'Sullivan MG, Allison DB, Jameson SC, Meves A, Li M, Prakash YS, Chiarella SE, Hamilton SE, Tchkonia T, Niedernhofer LJ, Kirkland JL, Robbins PD. Camell CD, et al. Science. 2021 Jul 16;373(6552):eabe4832. doi: 10.1126/science.abe4832. Epub 2021 Jun 8. Science. 2021. PMID: 34103349 Free PMC article.
Quercetin Blocks Ebola Virus Infection by Counteracting the VP24 Interferon-Inhibitory Function.
Fanunza E, Iampietro M, Distinto S, Corona A, Quartu M, Maccioni E, Horvat B, Tramontano E. Fanunza E, et al. Antimicrob Agents Chemother. 2020 Jun 23;64(7):e00530-20. doi: 10.1128/AAC.00530-20. Print 2020 Jun 23. Antimicrob Agents Chemother. 2020. PMID: 32366711 Free PMC article.
Ebola virus (EBOV) is among the most devastating pathogens causing fatal hemorrhagic fever in humans. ...Quercetin significantly blocked viral infection, specifically targeting EBOV VP24 anti-IFN-I function. ...
Ebola virus (EBOV) is among the most devastating pathogens causing fatal hemorrhagic fever in humans. ...Quercetin significant …
Oral supplementation of quercetin in PRRSV-1 modified-live virus vaccinated pigs in response to HP-PRRSV-2 challenge.
Ruansit W, Charerntantanakul W. Ruansit W, et al. Vaccine. 2020 Apr 23;38(19):3570-3581. doi: 10.1016/j.vaccine.2020.03.019. Epub 2020 Mar 14. Vaccine. 2020. PMID: 32184034
This study evaluated the immunomodulatory effect of quercetin on improving cross protection of porcine reproductive and respiratory syndrome virus-1 (PRRSV-1) modified-live virus (MLV) vaccine against highly pathogenic (HP)-PRRSV-2 challenge. ...Our findings …
This study evaluated the immunomodulatory effect of quercetin on improving cross protection of porcine reproductive and respiratory s …
Quercetin can reduce viral RNA level of O'nyong-nyong virus and resulting innate immune cytokine responses in cultured human synovial fibroblasts.
Septembre-Malaterre A, Bedoui Y, Giry C, Gasque P, Guiraud P, Sélambarom J. Septembre-Malaterre A, et al. Sci Rep. 2021 Mar 18;11(1):6369. doi: 10.1038/s41598-021-85840-z. Sci Rep. 2021. PMID: 33737658 Free PMC article.
O'nyong-nyong virus is an alphavirus closely related to chikungunya virus, causing arthralgia, rash and fever. ...These results highlighted the high value of the flavonol quercetin to reduce viral RNA levels and inflammatory status induced by ONNV in HSF cell …
O'nyong-nyong virus is an alphavirus closely related to chikungunya virus, causing arthralgia, rash and fever. ...These result …
308 results