Zinc(2+) ion inhibits SARS-CoV-2 main protease and viral replication in vitro.
Panchariya L, Khan WA, Kuila S, Sonkar K, Sahoo S, Ghoshal A, Kumar A, Verma DK, Hasan A, Khan MA, Jain N, Mohapatra AK, Das S, Thakur JK, Maiti S, Nanda RK, Halder R, Sunil S, Arockiasamy A.
Panchariya L, et al.
Chem Commun (Camb). 2021 Sep 30;57(78):10083-10086. doi: 10.1039/d1cc03563k.
Chem Commun (Camb). 2021.
PMID: 34514483
Zinc deficiency is linked to poor prognosis in COVID-19 patients while clinical trials with zinc demonstrate better clinical outcomes. The molecular targets and mechanistic details of the anti-coronaviral activity of zinc remain obscure. We show that zinc …
Zinc deficiency is linked to poor prognosis in COVID-19 patients while clinical trials with zinc demonstrate better clinical o …