Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1970 1
2000 1
2001 1
2002 2
2003 3
2004 7
2005 5
2006 5
2007 4
2008 9
2009 8
2010 10
2011 6
2012 10
2013 9
2014 13
2015 10
2016 21
2017 13
2018 8
2019 14
2020 24
2021 26
2022 14
2023 15
2024 15

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

232 results

Results by year

Filters applied: . Clear all
Page 1
Host-gut microbiota crosstalk predicts neuroinflammation.
Polonio CM, Quintana FJ. Polonio CM, et al. Among authors: quintana fj. Nat Microbiol. 2024 Sep;9(9):2204-2205. doi: 10.1038/s41564-024-01790-y. Nat Microbiol. 2024. PMID: 39160294 No abstract available.
Deletion of murine astrocytic vesicular nucleotide transporter increases anxiety and depressive-like behavior and attenuates motivation for reward.
Huang Q, Lee HH, Volpe B, Zhang Q, Xue C, Liu BC, Abuhasan YR, Li L, Yang JS, Egholm J, Gutierrez-Vazquez C, Li A, Lee A, Tang S, Wong CW, Liu T, Huang Y, Ramos RL, Stout RF, El Ouaamari A, Quintana FJ, Lowell BB, Kahn CR, Pothos EN, Cai W. Huang Q, et al. Among authors: quintana fj. Mol Psychiatry. 2024 Aug 9. doi: 10.1038/s41380-024-02692-5. Online ahead of print. Mol Psychiatry. 2024. PMID: 39122778
Astrocytes at the border of repair.
Lee HG, Quintana FJ. Lee HG, et al. Among authors: quintana fj. Nat Neurosci. 2024 Aug;27(8):1445-1446. doi: 10.1038/s41593-024-01670-y. Nat Neurosci. 2024. PMID: 38907164 No abstract available.
STING: Stay near to STIM(1) neuroprotection.
Lee HG, Quintana FJ. Lee HG, et al. Among authors: quintana fj. Mol Cell. 2024 Jul 25;84(14):2596-2597. doi: 10.1016/j.molcel.2024.06.034. Mol Cell. 2024. PMID: 39059368
Author Correction: Disease-associated astrocyte epigenetic memory promotes CNS pathology.
Lee HG, Rone JM, Li Z, Akl CF, Shin SW, Lee JH, Flausino LE, Pernin F, Chao CC, Kleemann KL, Srun L, Illouz T, Giovannoni F, Charabati M, Sanmarco LM, Kenison JE, Piester G, Zandee SEJ, Antel JP, Rothhammer V, Wheeler MA, Prat A, Clark IC, Quintana FJ. Lee HG, et al. Among authors: quintana fj. Nature. 2024 Jul;631(8020):E8. doi: 10.1038/s41586-024-07734-0. Nature. 2024. PMID: 38907058 No abstract available.
Tapinarof validates the aryl hydrocarbon receptor as a therapeutic target: A clinical review.
Silverberg JI, Boguniewicz M, Quintana FJ, Clark RA, Gross L, Hirano I, Tallman AM, Brown PM, Fredericks D, Rubenstein DS, McHale KA. Silverberg JI, et al. Among authors: quintana fj. J Allergy Clin Immunol. 2024 Jul;154(1):1-10. doi: 10.1016/j.jaci.2023.12.013. Epub 2023 Dec 27. J Allergy Clin Immunol. 2024. PMID: 38154665 Free article. Review.
Therapeutic induction of antigen-specific immune tolerance.
Kenison JE, Stevens NA, Quintana FJ. Kenison JE, et al. Among authors: quintana fj. Nat Rev Immunol. 2024 May;24(5):338-357. doi: 10.1038/s41577-023-00970-x. Epub 2023 Dec 12. Nat Rev Immunol. 2024. PMID: 38086932 Free PMC article. Review.
Charting the cellular biogeography in colitis reveals fibroblast trajectories and coordinated spatial remodeling.
Cadinu P, Sivanathan KN, Misra A, Xu RJ, Mangani D, Yang E, Rone JM, Tooley K, Kye YC, Bod L, Geistlinger L, Lee T, Mertens RT, Ono N, Wang G, Sanmarco L, Quintana FJ, Anderson AC, Kuchroo VK, Moffitt JR, Nowarski R. Cadinu P, et al. Among authors: quintana fj. Cell. 2024 Apr 11;187(8):2010-2028.e30. doi: 10.1016/j.cell.2024.03.013. Epub 2024 Apr 2. Cell. 2024. PMID: 38569542
Astrocyte control of brain metastasis.
Rone JM, Faust Akl C, Quintana FJ. Rone JM, et al. Among authors: quintana fj. Dev Cell. 2024 Mar 11;59(5):559-560. doi: 10.1016/j.devcel.2024.02.004. Dev Cell. 2024. PMID: 38471436
Disease-associated astrocyte epigenetic memory promotes CNS pathology.
Lee HG, Rone JM, Li Z, Akl CF, Shin SW, Lee JH, Flausino LE, Pernin F, Chao CC, Kleemann KL, Srun L, Illouz T, Giovannoni F, Charabati M, Sanmarco LM, Kenison JE, Piester G, Zandee SEJ, Antel JP, Rothhammer V, Wheeler MA, Prat A, Clark IC, Quintana FJ. Lee HG, et al. Among authors: quintana fj. Nature. 2024 Mar;627(8005):865-872. doi: 10.1038/s41586-024-07187-5. Epub 2024 Mar 20. Nature. 2024. PMID: 38509377
The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology.
Linnerbauer M, Lößlein L, Vandrey O, Peter A, Han Y, Tsaktanis T, Wogram E, Needhamsen M, Kular L, Nagel L, Zissler J, Andert M, Meszaros L, Hanspach J, Zuber F, Naumann UJ, Diebold M, Wheeler MA, Beyer T, Nirschl L, Cirac A, Laun FB, Günther C, Winkler J, Bäuerle T, Jagodic M, Hemmer B, Prinz M, Quintana FJ, Rothhammer V. Linnerbauer M, et al. Among authors: quintana fj. Nat Immunol. 2024 Mar;25(3):432-447. doi: 10.1038/s41590-024-01756-6. Epub 2024 Feb 26. Nat Immunol. 2024. PMID: 38409259 Free PMC article.
Association between altered tryptophan metabolism, plasma aryl hydrocarbon receptor agonists, and inflammatory Chagas disease.
Ambrosio LF, Volpini X, Quiroz JN, Brugo MB, Knubel CP, Herrera MR, Fozzatti L, Avila Pacheco J, Clish CB, Takenaka MC, Beloscar J, Theumer MG, Quintana FJ, Perez AR, Motrán CC. Ambrosio LF, et al. Among authors: quintana fj. Front Immunol. 2024 Jan 12;14:1267641. doi: 10.3389/fimmu.2023.1267641. eCollection 2023. Front Immunol. 2024. PMID: 38283348 Free PMC article.
Disease-associated astrocyte epigenetic memory promotes CNS pathology.
Lee HG, Rone JM, Li Z, Akl CF, Shin SW, Lee JH, Flausino LE, Pernin F, Chao CC, Kleemann KL, Srun L, Illouz T, Giovannoni F, Charabati M, Sanmarco LM, Kenison JE, Piester G, Zandee SEJ, Antel J, Rothhammer V, Wheeler MA, Prat A, Clark IC, Quintana FJ. Lee HG, et al. Among authors: quintana fj. bioRxiv [Preprint]. 2024 Jan 5:2024.01.04.574196. doi: 10.1101/2024.01.04.574196. bioRxiv. 2024. Update in: Nature. 2024 Mar;627(8005):865-872. doi: 10.1038/s41586-024-07187-5. PMID: 38260616 Free PMC article. Updated. Preprint.
Neuroinflammation: An astrocyte perspective.
Lee HG, Lee JH, Flausino LE, Quintana FJ. Lee HG, et al. Among authors: quintana fj. Sci Transl Med. 2023 Nov 8;15(721):eadi7828. doi: 10.1126/scitranslmed.adi7828. Epub 2023 Nov 8. Sci Transl Med. 2023. PMID: 37939162 Review.
PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation.
Linnerbauer M, Beyer T, Nirschl L, Farrenkopf D, Lößlein L, Vandrey O, Peter A, Tsaktanis T, Kebir H, Laplaud D, Oellinger R, Engleitner T, Alvarez JI, Rad R, Korn T, Hemmer B, Quintana FJ, Rothhammer V. Linnerbauer M, et al. Among authors: quintana fj. Nat Commun. 2023 Sep 9;14(1):5555. doi: 10.1038/s41467-023-40982-8. Nat Commun. 2023. PMID: 37689786 Free PMC article.
Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells.
Sanmarco LM, Rone JM, Polonio CM, Fernandez Lahore G, Giovannoni F, Ferrara K, Gutierrez-Vazquez C, Li N, Sokolovska A, Plasencia A, Faust Akl C, Nanda P, Heck ES, Li Z, Lee HG, Chao CC, Rejano-Gordillo CM, Fonseca-Castro PH, Illouz T, Linnerbauer M, Kenison JE, Barilla RM, Farrenkopf D, Stevens NA, Piester G, Chung EN, Dailey L, Kuchroo VK, Hava D, Wheeler MA, Clish C, Nowarski R, Balsa E, Lora JM, Quintana FJ. Sanmarco LM, et al. Among authors: quintana fj. Nature. 2023 Aug;620(7975):881-889. doi: 10.1038/s41586-023-06409-6. Epub 2023 Aug 9. Nature. 2023. PMID: 37558878 Free PMC article.
Regulation of the programmed cell death protein 1/programmed cell death ligand 1 axis in relapsing-remitting multiple sclerosis.
Tsaktanis T, Linnerbauer M, Lößlein L, Farrenkopf D, Vandrey O, Peter A, Cirac A, Beyer T, Nirschl L, Grummel V, Mühlau M, Bussas M, Hemmer B, Quintana FJ, Rothhammer V. Tsaktanis T, et al. Among authors: quintana fj. Brain Commun. 2023 Jul 25;5(4):fcad206. doi: 10.1093/braincomms/fcad206. eCollection 2023. Brain Commun. 2023. PMID: 37564830 Free PMC article.
B-cell-specific checkpoint molecules that regulate anti-tumour immunity.
Bod L, Kye YC, Shi J, Torlai Triglia E, Schnell A, Fessler J, Ostrowski SM, Von-Franque MY, Kuchroo JR, Barilla RM, Zaghouani S, Christian E, Delorey TM, Mohib K, Xiao S, Slingerland N, Giuliano CJ, Ashenberg O, Li Z, Rothstein DM, Fisher DE, Rozenblatt-Rosen O, Sharpe AH, Quintana FJ, Apetoh L, Regev A, Kuchroo VK. Bod L, et al. Among authors: quintana fj. Nature. 2023 Jul;619(7969):348-356. doi: 10.1038/s41586-023-06231-0. Epub 2023 Jun 21. Nature. 2023. PMID: 37344597 Free PMC article.
Charting the cellular biogeography in colitis reveals fibroblast trajectories and coordinated spatial remodeling.
Cadinu P, Sivanathan KN, Misra A, Xu RJ, Mangani D, Yang E, Rone JM, Tooley K, Kye YC, Bod L, Geistlinger L, Lee T, Ono N, Wang G, Sanmarco L, Quintana FJ, Anderson AC, Kuchroo VK, Moffitt JR, Nowarski R. Cadinu P, et al. Among authors: quintana fj. bioRxiv [Preprint]. 2023 May 9:2023.05.08.539701. doi: 10.1101/2023.05.08.539701. bioRxiv. 2023. Update in: Cell. 2024 Apr 11;187(8):2010-2028.e30. doi: 10.1016/j.cell.2024.03.013. PMID: 37214800 Free PMC article. Updated. Preprint.
Engineered probiotics limit CNS autoimmunity by stabilizing HIF-1α in dendritic cells.
Sanmarco LM, Rone JM, Polonio CM, Giovannoni F, Lahore GF, Ferrara K, Gutierrez-Vazquez C, Li N, Sokolovska A, Plasencia A, Akl CF, Nanda P, Heck ES, Li Z, Lee HG, Chao CC, Rejano-Gordillo CM, Fonseca-Castro PH, Illouz T, Linnerbauer M, Kenison JE, Barilla RM, Farrenkopf D, Piester G, Dailey L, Kuchroo VK, Hava D, Wheeler MA, Clish C, Nowarski R, Balsa E, Lora JM, Quintana FJ. Sanmarco LM, et al. Among authors: quintana fj. bioRxiv [Preprint]. 2023 Mar 21:2023.03.17.532101. doi: 10.1101/2023.03.17.532101. bioRxiv. 2023. Update in: Nature. 2023 Aug;620(7975):881-889. doi: 10.1038/s41586-023-06409-6. PMID: 36993446 Free PMC article. Updated. Preprint.
Droplet-based forward genetic screening of astrocyte-microglia cross-talk.
Wheeler MA, Clark IC, Lee HG, Li Z, Linnerbauer M, Rone JM, Blain M, Akl CF, Piester G, Giovannoni F, Charabati M, Lee JH, Kye YC, Choi J, Sanmarco LM, Srun L, Chung EN, Flausino LE, Andersen BM, Rothhammer V, Yano H, Illouz T, Zandee SEJ, Daniel C, Artis D, Prinz M, Abate AR, Kuchroo VK, Antel JP, Prat A, Quintana FJ. Wheeler MA, et al. Among authors: quintana fj. Science. 2023 Mar 10;379(6636):1023-1030. doi: 10.1126/science.abq4822. Epub 2023 Mar 9. Science. 2023. PMID: 36893254 Free PMC article.
HIV silencing and cell survival signatures in infected T cell reservoirs.
Clark IC, Mudvari P, Thaploo S, Smith S, Abu-Laban M, Hamouda M, Theberge M, Shah S, Ko SH, Pérez L, Bunis DG, Lee JS, Kilam D, Zakaria S, Choi S, Darko S, Henry AR, Wheeler MA, Hoh R, Butrus S, Deeks SG, Quintana FJ, Douek DC, Abate AR, Boritz EA. Clark IC, et al. Among authors: quintana fj. Nature. 2023 Feb;614(7947):318-325. doi: 10.1038/s41586-022-05556-6. Epub 2023 Jan 4. Nature. 2023. PMID: 36599978 Free PMC article.
Identification of astrocyte regulators by nucleic acid cytometry.
Clark IC, Wheeler MA, Lee HG, Li Z, Sanmarco LM, Thaploo S, Polonio CM, Shin SW, Scalisi G, Henry AR, Rone JM, Giovannoni F, Charabati M, Akl CF, Aleman DM, Zandee SEJ, Prat A, Douek DC, Boritz EA, Quintana FJ, Abate AR. Clark IC, et al. Among authors: quintana fj. Nature. 2023 Feb;614(7947):326-333. doi: 10.1038/s41586-022-05613-0. Epub 2023 Jan 4. Nature. 2023. PMID: 36599367 Free PMC article.
Identification of environmental factors that promote intestinal inflammation.
Sanmarco LM, Chao CC, Wang YC, Kenison JE, Li Z, Rone JM, Rejano-Gordillo CM, Polonio CM, Gutierrez-Vazquez C, Piester G, Plasencia A, Li L, Giovannoni F, Lee HG, Faust Akl C, Wheeler MA, Mascanfroni I, Jaronen M, Alsuwailm M, Hewson P, Yeste A, Andersen BM, Franks DG, Huang CJ, Ekwudo M, Tjon EC, Rothhammer V, Takenaka M, de Lima KA, Linnerbauer M, Guo L, Covacu R, Queva H, Fonseca-Castro PH, Bladi MA, Cox LM, Hodgetts KJ, Hahn ME, Mildner A, Korzenik J, Hauser R, Snapper SB, Quintana FJ. Sanmarco LM, et al. Among authors: quintana fj. Nature. 2022 Nov;611(7937):801-809. doi: 10.1038/s41586-022-05308-6. Epub 2022 Oct 20. Nature. 2022. PMID: 36266581 Free PMC article.
Glucose promotes regulatory T cell differentiation to maintain intestinal homeostasis.
Yu Y, Yang W, Yu T, Zhao X, Zhou Z, Yu Y, Xiong L, Yang H, Bilotta AJ, Yao S, Golovko G, Plasencia A, Quintana FJ, Zhou L, Li Y, Cong Y. Yu Y, et al. Among authors: quintana fj. iScience. 2022 Aug 24;25(9):105004. doi: 10.1016/j.isci.2022.105004. eCollection 2022 Sep 16. iScience. 2022. PMID: 36093065 Free PMC article.
Glioblastoma scRNA-seq shows treatment-induced, immune-dependent increase in mesenchymal cancer cells and structural variants in distal neural stem cells.
Couturier CP, Nadaf J, Li Z, Baig S, Riva G, Le P, Kloosterman DJ, Monlong J, Nkili Meyong A, Allache R, Degenhard T, Al-Rashid M, Guiot MC, Bourque G, Ragoussis J, Akkari L, Quintana FJ, Petrecca K. Couturier CP, et al. Among authors: quintana fj. Neuro Oncol. 2022 Sep 1;24(9):1494-1508. doi: 10.1093/neuonc/noac085. Neuro Oncol. 2022. PMID: 35416251 Free PMC article.
Analysis of chronic kidney disease patients by targeted next-generation sequencing identifies novel variants in kidney-related genes.
Alaamery M, Alghamdi J, Massadeh S, Alsawaji M, Aljawini N, Albesher N, Alghamdi B, Almutairi M, Hejaili F, Alfadhel M, Baz B, Almuzzaini B, Almutairi AF, Abdullah M, Quintana FJ, Sayyari A. Alaamery M, et al. Among authors: quintana fj. Front Genet. 2022 Aug 11;13:886038. doi: 10.3389/fgene.2022.886038. eCollection 2022. Front Genet. 2022. PMID: 36035137 Free PMC article.
Neuro-immune crosstalk in drug-resistant epilepsy.
Andersen BM, Quintana FJ. Andersen BM, et al. Among authors: quintana fj. Nat Neurosci. 2022 Jul;25(7):843-844. doi: 10.1038/s41593-022-01112-7. Nat Neurosci. 2022. PMID: 35739272 No abstract available.
The Immune Response in Multiple Sclerosis.
Rodríguez Murúa S, Farez MF, Quintana FJ. Rodríguez Murúa S, et al. Among authors: quintana fj. Annu Rev Pathol. 2022 Jan 24;17:121-139. doi: 10.1146/annurev-pathol-052920-040318. Epub 2021 Oct 4. Annu Rev Pathol. 2022. PMID: 34606377 Review.
DICAM promotes TH17 lymphocyte trafficking across the blood-brain barrier during autoimmune neuroinflammation.
Charabati M, Grasmuck C, Ghannam S, Bourbonnière L, Fournier AP, Lécuyer MA, Tastet O, Kebir H, Rébillard RM, Hoornaert C, Gowing E, Larouche S, Fortin O, Pittet C, Filali-Mouhim A, Lahav B, Moumdjian R, Bouthillier A, Girard M, Duquette P, Cayrol R, Peelen E, Quintana FJ, Antel JP, Flügel A, Larochelle C, Arbour N, Zandee S, Prat A. Charabati M, et al. Among authors: quintana fj. Sci Transl Med. 2022 Jan 5;14(626):eabj0473. doi: 10.1126/scitranslmed.abj0473. Epub 2022 Jan 5. Sci Transl Med. 2022. PMID: 34985970
Synthetic biology: at the crossroads of genetic engineering and human therapeutics-a Keystone Symposia report.
Cable J, Leonard JN, Lu TK, Xie Z, Chang MW, Fernández LÁ, Lora JM, Kaufman HL, Quintana FJ, Geiger R, F Lesser C, Lynch JP, Hava DL, Cornish VW, Lee GK, DiAndreth B, Fero M, Srivastava R, De Coster T, Roybal KT, Rackham OJL, Kiani S, Zhu I, Hernandez-Lopez RA, Guo T, Chen WCW. Cable J, et al. Among authors: quintana fj. Ann N Y Acad Sci. 2021 Dec;1506(1):98-117. doi: 10.1111/nyas.14710. Epub 2021 Nov 16. Ann N Y Acad Sci. 2021. PMID: 34786712 Review.
Glial and myeloid heterogeneity in the brain tumour microenvironment.
Andersen BM, Faust Akl C, Wheeler MA, Chiocca EA, Reardon DA, Quintana FJ. Andersen BM, et al. Among authors: quintana fj. Nat Rev Cancer. 2021 Dec;21(12):786-802. doi: 10.1038/s41568-021-00397-3. Epub 2021 Sep 28. Nat Rev Cancer. 2021. PMID: 34584243 Free PMC article. Review.
Repositioning TH cell polarization from single cytokines to complex help.
Tuzlak S, Dejean AS, Iannacone M, Quintana FJ, Waisman A, Ginhoux F, Korn T, Becher B. Tuzlak S, et al. Among authors: quintana fj. Nat Immunol. 2021 Oct;22(10):1210-1217. doi: 10.1038/s41590-021-01009-w. Epub 2021 Sep 20. Nat Immunol. 2021. PMID: 34545250 Review.
Functional immune cell-astrocyte interactions.
Sanmarco LM, Polonio CM, Wheeler MA, Quintana FJ. Sanmarco LM, et al. Among authors: quintana fj. J Exp Med. 2021 Sep 6;218(9):e20202715. doi: 10.1084/jem.20202715. Epub 2021 Jul 22. J Exp Med. 2021. PMID: 34292315 Free PMC article. Review.
AHR signaling is induced by infection with coronaviruses.
Giovannoni F, Li Z, Remes-Lenicov F, Dávola ME, Elizalde M, Paletta A, Ashkar AA, Mossman KL, Dugour AV, Figueroa JM, Barquero AA, Ceballos A, Garcia CC, Quintana FJ. Giovannoni F, et al. Among authors: quintana fj. Nat Commun. 2021 Aug 26;12(1):5148. doi: 10.1038/s41467-021-25412-x. Nat Commun. 2021. PMID: 34446714 Free PMC article.
TrbK controls astrocyte-driven oligodendrocyte copper poisoning.
Quintana FJ, Weiner HL. Quintana FJ, et al. Proc Natl Acad Sci U S A. 2021 Aug 10;118(32):e2110998118. doi: 10.1073/pnas.2110998118. Proc Natl Acad Sci U S A. 2021. PMID: 34344829 Free PMC article. No abstract available.
Treatment of chronic diabetic foot ulcers with adipose-derived stromal vascular fraction cell injections: Safety and evidence of efficacy at 1 year.
Carstens MH, Quintana FJ, Calderwood ST, Sevilla JP, Ríos AB, Rivera CM, Calero DW, Zelaya ML, Garcia N, Bertram KA, Rigdon J, Dos-Anjos S, Correa D. Carstens MH, et al. Among authors: quintana fj. Stem Cells Transl Med. 2021 Aug;10(8):1138-1147. doi: 10.1002/sctm.20-0497. Epub 2021 Apr 7. Stem Cells Transl Med. 2021. PMID: 33826245 Free PMC article. Clinical Trial.
The Aryl Hydrocarbon Receptor-Dependent TGF-α/VEGF-B Ratio Correlates With Disease Subtype and Prognosis in Multiple Sclerosis.
Cirac A, Tsaktanis T, Beyer T, Linnerbauer M, Andlauer T, Grummel V, Nirschl L, Loesslein L, Quintana FJ, Hemmer B, Rothhammer V. Cirac A, et al. Among authors: quintana fj. Neurol Neuroimmunol Neuroinflamm. 2021 Jul 23;8(5):e1043. doi: 10.1212/NXI.0000000000001043. Print 2021 Jul. Neurol Neuroimmunol Neuroinflamm. 2021. PMID: 34301821 Free PMC article.
Tryptophan metabolism drives dynamic immunosuppressive myeloid states in IDH-mutant gliomas.
Friedrich M, Sankowski R, Bunse L, Kilian M, Green E, Ramallo Guevara C, Pusch S, Poschet G, Sanghvi K, Hahn M, Bunse T, Münch P, Gegner HM, Sonner JK, von Landenberg A, Cichon F, Aslan K, Trobisch T, Schirmer L, Abu-Sammour D, Kessler T, Ratliff M, Schrimpf D, Sahm F, Hopf C, Heiland DH, Schnell O, Beck J, Böttcher C, Fernandez-Zapata C, Priller J, Heiland S, Gutcher I, Quintana FJ, von Deimling A, Wick W, Prinz M, Platten M. Friedrich M, et al. Among authors: quintana fj. Nat Cancer. 2021 Jul;2(7):723-740. doi: 10.1038/s43018-021-00201-z. Epub 2021 May 24. Nat Cancer. 2021. PMID: 35121943
Self-tunable engineered yeast probiotics for the treatment of inflammatory bowel disease.
Scott BM, Gutiérrez-Vázquez C, Sanmarco LM, da Silva Pereira JA, Li Z, Plasencia A, Hewson P, Cox LM, O'Brien M, Chen SK, Moraes-Vieira PM, Chang BSW, Peisajovich SG, Quintana FJ. Scott BM, et al. Among authors: quintana fj. Nat Med. 2021 Jul;27(7):1212-1222. doi: 10.1038/s41591-021-01390-x. Epub 2021 Jun 28. Nat Med. 2021. PMID: 34183837
Role of sphingolipid metabolism in neurodegeneration.
Alaamery M, Albesher N, Aljawini N, Alsuwailm M, Massadeh S, Wheeler MA, Chao CC, Quintana FJ. Alaamery M, et al. Among authors: quintana fj. J Neurochem. 2021 Jul;158(1):25-35. doi: 10.1111/jnc.15044. Epub 2020 Jul 3. J Neurochem. 2021. PMID: 32402091 Free PMC article. Review.
A cell-based drug delivery platform for treating central nervous system inflammation.
Levy O, Rothhammer V, Mascanfroni I, Tong Z, Kuai R, De Biasio M, Wang Q, Majid T, Perrault C, Yeste A, Kenison JE, Safaee H, Musabeyezu J, Heinelt M, Milton Y, Kuang H, Lan H, Siders W, Multon MC, Rothblatt J, Massadeh S, Alaamery M, Alhasan AH, Quintana FJ, Karp JM. Levy O, et al. Among authors: quintana fj. J Mol Med (Berl). 2021 May;99(5):663-671. doi: 10.1007/s00109-020-02003-9. Epub 2021 Jan 4. J Mol Med (Berl). 2021. PMID: 33398468 Free PMC article.
Barcoded viral tracing of single-cell interactions in central nervous system inflammation.
Clark IC, Gutiérrez-Vázquez C, Wheeler MA, Li Z, Rothhammer V, Linnerbauer M, Sanmarco LM, Guo L, Blain M, Zandee SEJ, Chao CC, Batterman KV, Schwabenland M, Lotfy P, Tejeda-Velarde A, Hewson P, Manganeli Polonio C, Shultis MW, Salem Y, Tjon EC, Fonseca-Castro PH, Borucki DM, Alves de Lima K, Plasencia A, Abate AR, Rosene DL, Hodgetts KJ, Prinz M, Antel JP, Prat A, Quintana FJ. Clark IC, et al. Among authors: quintana fj. Science. 2021 Apr 23;372(6540):eabf1230. doi: 10.1126/science.abf1230. Science. 2021. PMID: 33888612 Free PMC article.
The Aryl Hydrocarbon Receptor as a Modulator of Anti-viral Immunity.
Torti MF, Giovannoni F, Quintana FJ, García CC. Torti MF, et al. Among authors: quintana fj. Front Immunol. 2021 Mar 5;12:624293. doi: 10.3389/fimmu.2021.624293. eCollection 2021. Front Immunol. 2021. PMID: 33746961 Free PMC article. Review.
Reactive astrocyte nomenclature, definitions, and future directions.
Escartin C, Galea E, Lakatos A, O'Callaghan JP, Petzold GC, Serrano-Pozo A, Steinhäuser C, Volterra A, Carmignoto G, Agarwal A, Allen NJ, Araque A, Barbeito L, Barzilai A, Bergles DE, Bonvento G, Butt AM, Chen WT, Cohen-Salmon M, Cunningham C, Deneen B, De Strooper B, Díaz-Castro B, Farina C, Freeman M, Gallo V, Goldman JE, Goldman SA, Götz M, Gutiérrez A, Haydon PG, Heiland DH, Hol EM, Holt MG, Iino M, Kastanenka KV, Kettenmann H, Khakh BS, Koizumi S, Lee CJ, Liddelow SA, MacVicar BA, Magistretti P, Messing A, Mishra A, Molofsky AV, Murai KK, Norris CM, Okada S, Oliet SHR, Oliveira JF, Panatier A, Parpura V, Pekna M, Pekny M, Pellerin L, Perea G, Pérez-Nievas BG, Pfrieger FW, Poskanzer KE, Quintana FJ, Ransohoff RM, Riquelme-Perez M, Robel S, Rose CR, Rothstein JD, Rouach N, Rowitch DH, Semyanov A, Sirko S, Sontheimer H, Swanson RA, Vitorica J, Wanner IB, Wood LB, Wu J, Zheng B, Zimmer ER, Zorec R, Sofroniew MV, Verkhratsky A. Escartin C, et al. Among authors: quintana fj. Nat Neurosci. 2021 Mar;24(3):312-325. doi: 10.1038/s41593-020-00783-4. Epub 2021 Feb 15. Nat Neurosci. 2021. PMID: 33589835 Free PMC article. Review.
Aryl Hydrocarbon Receptor Plasma Agonist Activity Correlates With Disease Activity in Progressive MS.
Tsaktanis T, Beyer T, Nirschl L, Linnerbauer M, Grummel V, Bussas M, Tjon E, Mühlau M, Korn T, Hemmer B, Quintana FJ, Rothhammer V. Tsaktanis T, et al. Among authors: quintana fj. Neurol Neuroimmunol Neuroinflamm. 2020 Dec 24;8(2):e933. doi: 10.1212/NXI.0000000000000933. Print 2021 Mar. Neurol Neuroimmunol Neuroinflamm. 2020. PMID: 33361385 Free PMC article.
Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes.
Sanmarco LM, Wheeler MA, Gutiérrez-Vázquez C, Polonio CM, Linnerbauer M, Pinho-Ribeiro FA, Li Z, Giovannoni F, Batterman KV, Scalisi G, Zandee SEJ, Heck ES, Alsuwailm M, Rosene DL, Becher B, Chiu IM, Prat A, Quintana FJ. Sanmarco LM, et al. Among authors: quintana fj. Nature. 2021 Feb;590(7846):473-479. doi: 10.1038/s41586-020-03116-4. Epub 2021 Jan 6. Nature. 2021. PMID: 33408417 Free PMC article.
The aryl hydrocarbon receptor and the gut-brain axis.
Barroso A, Mahler JV, Fonseca-Castro PH, Quintana FJ. Barroso A, et al. Among authors: quintana fj. Cell Mol Immunol. 2021 Feb;18(2):259-268. doi: 10.1038/s41423-020-00585-5. Epub 2021 Jan 6. Cell Mol Immunol. 2021. PMID: 33408340 Free PMC article. Review.
Tolerogenic nanoparticles suppress central nervous system inflammation.
Kenison JE, Jhaveri A, Li Z, Khadse N, Tjon E, Tezza S, Nowakowska D, Plasencia A, Stanton VP Jr, Sherr DH, Quintana FJ. Kenison JE, et al. Among authors: quintana fj. Proc Natl Acad Sci U S A. 2020 Dec 15;117(50):32017-32028. doi: 10.1073/pnas.2016451117. Epub 2020 Nov 25. Proc Natl Acad Sci U S A. 2020. PMID: 33239445 Free PMC article.
T Follicular Regulatory Cell-Derived Fibrinogen-like Protein 2 Regulates Production of Autoantibodies and Induction of Systemic Autoimmunity.
Sungnak W, Wagner A, Kowalczyk MS, Bod L, Kye YC, Sage PT, Sharpe AH, Sobel RA, Quintana FJ, Rozenblatt-Rosen O, Regev A, Wang C, Yosef N, Kuchroo VK. Sungnak W, et al. Among authors: quintana fj. J Immunol. 2020 Dec 15;205(12):3247-3262. doi: 10.4049/jimmunol.2000748. Epub 2020 Nov 9. J Immunol. 2020. PMID: 33168576 Free PMC article.
From initial segment to cauda: a regional characterization of mouse epididymal CD11c+ mononuclear phagocytes based on immune phenotype and function.
Mendelsohn AC, Sanmarco LM, Spallanzani RG, Brown D, Quintana FJ, Breton S, Battistone MA. Mendelsohn AC, et al. Among authors: quintana fj. Am J Physiol Cell Physiol. 2020 Dec 1;319(6):C997-C1010. doi: 10.1152/ajpcell.00392.2020. Epub 2020 Sep 29. Am J Physiol Cell Physiol. 2020. PMID: 32991210 Free PMC article.
Astrocyte Crosstalk in CNS Inflammation.
Linnerbauer M, Wheeler MA, Quintana FJ. Linnerbauer M, et al. Among authors: quintana fj. Neuron. 2020 Nov 25;108(4):608-622. doi: 10.1016/j.neuron.2020.08.012. Epub 2020 Sep 7. Neuron. 2020. PMID: 32898475 Free PMC article. Review.
Negative feedback control of neuronal activity by microglia.
Badimon A, Strasburger HJ, Ayata P, Chen X, Nair A, Ikegami A, Hwang P, Chan AT, Graves SM, Uweru JO, Ledderose C, Kutlu MG, Wheeler MA, Kahan A, Ishikawa M, Wang YC, Loh YE, Jiang JX, Surmeier DJ, Robson SC, Junger WG, Sebra R, Calipari ES, Kenny PJ, Eyo UB, Colonna M, Quintana FJ, Wake H, Gradinaru V, Schaefer A. Badimon A, et al. Among authors: quintana fj. Nature. 2020 Oct;586(7829):417-423. doi: 10.1038/s41586-020-2777-8. Epub 2020 Sep 30. Nature. 2020. PMID: 32999463 Free PMC article.
Author Correction: AHR is a Zika virus host factor and a candidate target for antiviral therapy.
Giovannoni F, Bosch I, Polonio CM, Torti MF, Wheeler MA, Li Z, Romorini L, Rodriguez Varela MS, Rothhammer V, Barroso A, Tjon EC, Sanmarco LM, Takenaka MC, Modaresi SMS, Gutiérrez-Vázquez C, Zanluqui NG, Dos Santos NB, Munhoz CD, Wang Z, Damonte EB, Sherr D, Gehrke L, Peron JPS, Garcia CC, Quintana FJ. Giovannoni F, et al. Among authors: quintana fj. Nat Neurosci. 2020 Oct;23(10):1307. doi: 10.1038/s41593-020-0700-0. Nat Neurosci. 2020. PMID: 32778795
The Role of Astrocytes in CNS Inflammation.
Giovannoni F, Quintana FJ. Giovannoni F, et al. Among authors: quintana fj. Trends Immunol. 2020 Sep;41(9):805-819. doi: 10.1016/j.it.2020.07.007. Epub 2020 Aug 13. Trends Immunol. 2020. PMID: 32800705 Free PMC article. Review.
AHR is a Zika virus host factor and a candidate target for antiviral therapy.
Giovannoni F, Bosch I, Polonio CM, Torti MF, Wheeler MA, Li Z, Romorini L, Rodriguez Varela MS, Rothhammer V, Barroso A, Tjon EC, Sanmarco LM, Takenaka MC, Modaresi SMS, Gutiérrez-Vázquez C, Zanluqui NG, Dos Santos NB, Munhoz CD, Wang Z, Damonte EB, Sherr D, Gehrke L, Peron JPS, Garcia CC, Quintana FJ. Giovannoni F, et al. Among authors: quintana fj. Nat Neurosci. 2020 Aug;23(8):939-951. doi: 10.1038/s41593-020-0664-0. Epub 2020 Jul 20. Nat Neurosci. 2020. PMID: 32690969 Free PMC article.
The Gut-CNS Axis in Multiple Sclerosis.
Kadowaki A, Quintana FJ. Kadowaki A, et al. Among authors: quintana fj. Trends Neurosci. 2020 Aug;43(8):622-634. doi: 10.1016/j.tins.2020.06.002. Epub 2020 Jul 7. Trends Neurosci. 2020. PMID: 32650957 Free PMC article. Review.
Role of AHR in the control of GBM-associated myeloid cells.
Gabriely G, Quintana FJ. Gabriely G, et al. Among authors: quintana fj. Semin Cancer Biol. 2020 Aug;64:13-18. doi: 10.1016/j.semcancer.2019.05.014. Epub 2019 May 23. Semin Cancer Biol. 2020. PMID: 31128300 Free PMC article. Review.
Checkpoint Receptor TIGIT Expressed on Tim-1+ B Cells Regulates Tissue Inflammation.
Xiao S, Bod L, Pochet N, Kota SB, Hu D, Madi A, Kilpatrick J, Shi J, Ho A, Zhang H, Sobel R, Weiner HL, Strom TB, Quintana FJ, Joller N, Kuchroo VK. Xiao S, et al. Among authors: quintana fj. Cell Rep. 2020 Jul 14;32(2):107892. doi: 10.1016/j.celrep.2020.107892. Cell Rep. 2020. PMID: 32668241 Free PMC article.
Serum antibodies to phosphatidylcholine in MS.
Sádaba MC, Rothhammer V, Muñoz Ú, Sebal C, Escudero E, Kivisäkk P, Garcia Sanchez MI, Izquierdo G, Hauser SL, Baranzini SE, Oksenberg JR, Álvarez-Lafuente R, Bakshi R, Weiner HL, Quintana FJ. Sádaba MC, et al. Among authors: quintana fj. Neurol Neuroimmunol Neuroinflamm. 2020 Jun 9;7(4):e765. doi: 10.1212/NXI.0000000000000765. Print 2020 Jul. Neurol Neuroimmunol Neuroinflamm. 2020. PMID: 32518205 Free PMC article.
DNA vaccine encoding heat shock protein 90 protects from murine lupus.
Liu A, Shi FD, Cohen IR, Castaldo G, Matarese G, Quintana FJ, La Cava A. Liu A, et al. Among authors: quintana fj. Arthritis Res Ther. 2020 Jun 22;22(1):152. doi: 10.1186/s13075-020-02246-4. Arthritis Res Ther. 2020. PMID: 32571400 Free PMC article.
Activin-A limits Th17 pathogenicity and autoimmune neuroinflammation via CD39 and CD73 ectonucleotidases and Hif1-α-dependent pathways.
Morianos I, Trochoutsou AI, Papadopoulou G, Semitekolou M, Banos A, Konstantopoulos D, Manousopoulou A, Kapasa M, Wei P, Lomenick B, Belaidi E, Kalamatas T, Karageorgiou K, Doskas T, Sallusto F, Pan F, Garbis SD, Quintana FJ, Xanthou G. Morianos I, et al. Among authors: quintana fj. Proc Natl Acad Sci U S A. 2020 Jun 2;117(22):12269-12280. doi: 10.1073/pnas.1918196117. Epub 2020 May 14. Proc Natl Acad Sci U S A. 2020. PMID: 32409602 Free PMC article.
Imaging-AMARETTO: An Imaging Genomics Software Tool to Interrogate Multiomics Networks for Relevance to Radiography and Histopathology Imaging Biomarkers of Clinical Outcomes.
Gevaert O, Nabian M, Bakr S, Everaert C, Shinde J, Manukyan A, Liefeld T, Tabor T, Xu J, Lupberger J, Haas BJ, Baumert TF, Hernaez M, Reich M, Quintana FJ, Uhlmann EJ, Krichevsky AM, Mesirov JP, Carey V, Pochet N. Gevaert O, et al. Among authors: quintana fj. JCO Clin Cancer Inform. 2020 May;4:421-435. doi: 10.1200/CCI.19.00125. JCO Clin Cancer Inform. 2020. PMID: 32383980 Free PMC article.
A potential role for AHR in SARS-CoV-2 pathology.
Giovannoni F, Li Z, Garcia CC, Quintana FJ. Giovannoni F, et al. Among authors: quintana fj. Res Sq [Preprint]. 2020 Apr 27:rs.3.rs-25639. doi: 10.21203/rs.3.rs-25639/v1. Res Sq. 2020. PMID: 32702728 Free PMC article. Preprint.
MAFG-driven astrocytes promote CNS inflammation.
Wheeler MA, Clark IC, Tjon EC, Li Z, Zandee SEJ, Couturier CP, Watson BR, Scalisi G, Alkwai S, Rothhammer V, Rotem A, Heyman JA, Thaploo S, Sanmarco LM, Ragoussis J, Weitz DA, Petrecca K, Moffitt JR, Becher B, Antel JP, Prat A, Quintana FJ. Wheeler MA, et al. Among authors: quintana fj. Nature. 2020 Feb;578(7796):593-599. doi: 10.1038/s41586-020-1999-0. Epub 2020 Feb 12. Nature. 2020. PMID: 32051591 Free PMC article.
Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS.
Chao CC, Gutiérrez-Vázquez C, Rothhammer V, Mayo L, Wheeler MA, Tjon EC, Zandee SEJ, Blain M, de Lima KA, Takenaka MC, Avila-Pacheco J, Hewson P, Liu L, Sanmarco LM, Borucki DM, Lipof GZ, Trauger SA, Clish CB, Antel JP, Prat A, Quintana FJ. Chao CC, et al. Among authors: quintana fj. Cell. 2019 Dec 12;179(7):1483-1498.e22. doi: 10.1016/j.cell.2019.11.016. Epub 2019 Dec 5. Cell. 2019. PMID: 31813625 Free PMC article.
Author Correction: Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39.
Takenaka MC, Gabriely G, Rothhammer V, Mascanfroni ID, Wheeler MA, Chao CC, Gutiérrez-Vázquez C, Kenison J, Tjon EC, Barroso A, Vandeventer T, de Lima KA, Rothweiler S, Mayo L, Ghannam S, Zandee S, Healy L, Sherr D, Farez MF, Prat A, Antel J, Reardon DA, Zhang H, Robson SC, Getz G, Weiner HL, Quintana FJ. Takenaka MC, et al. Among authors: quintana fj. Nat Neurosci. 2019 Sep;22(9):1533. doi: 10.1038/s41593-019-0446-8. Nat Neurosci. 2019. PMID: 31197266 Free PMC article.
Meningeal Memories of Viral Infection.
Sanmarco LM, Quintana FJ. Sanmarco LM, et al. Among authors: quintana fj. Trends Neurosci. 2019 Aug;42(8):513-514. doi: 10.1016/j.tins.2019.06.001. Epub 2019 Jun 25. Trends Neurosci. 2019. PMID: 31253444
Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39.
Takenaka MC, Gabriely G, Rothhammer V, Mascanfroni ID, Wheeler MA, Chao CC, Gutiérrez-Vázquez C, Kenison J, Tjon EC, Barroso A, Vandeventer T, de Lima KA, Rothweiler S, Mayo L, Ghannam S, Zandee S, Healy L, Sherr D, Farez MF, Prat A, Antel J, Reardon DA, Zhang H, Robson SC, Getz G, Weiner HL, Quintana FJ. Takenaka MC, et al. Among authors: quintana fj. Nat Neurosci. 2019 May;22(5):729-740. doi: 10.1038/s41593-019-0370-y. Epub 2019 Apr 8. Nat Neurosci. 2019. PMID: 30962630 Free PMC article.
MRI phenotypes in MS: Longitudinal changes and miRNA signatures.
Hemond CC, Healy BC, Tauhid S, Mazzola MA, Quintana FJ, Gandhi R, Weiner HL, Bakshi R. Hemond CC, et al. Among authors: quintana fj. Neurol Neuroimmunol Neuroinflamm. 2019 Feb 14;6(2):e530. doi: 10.1212/NXI.0000000000000530. eCollection 2019 Mar. Neurol Neuroimmunol Neuroinflamm. 2019. PMID: 30800720 Free PMC article.
Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation.
Wheeler MA, Jaronen M, Covacu R, Zandee SEJ, Scalisi G, Rothhammer V, Tjon EC, Chao CC, Kenison JE, Blain M, Rao VTS, Hewson P, Barroso A, Gutiérrez-Vázquez C, Prat A, Antel JP, Hauser R, Quintana FJ. Wheeler MA, et al. Among authors: quintana fj. Cell. 2019 Jan 24;176(3):581-596.e18. doi: 10.1016/j.cell.2018.12.012. Epub 2019 Jan 17. Cell. 2019. PMID: 30661753 Free PMC article.
Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation.
Starossom SC, Campo Garcia J, Woelfle T, Romero-Suarez S, Olah M, Watanabe F, Cao L, Yeste A, Tukker JJ, Quintana FJ, Imitola J, Witzel F, Schmitz D, Morkel M, Paul F, Infante-Duarte C, Khoury SJ. Starossom SC, et al. Among authors: quintana fj. Nat Commun. 2019 Jan 15;10(1):217. doi: 10.1038/s41467-018-08140-7. Nat Commun. 2019. PMID: 30644388 Free PMC article.
Regulation of Astrocyte Functions in Multiple Sclerosis.
Wheeler MA, Quintana FJ. Wheeler MA, et al. Among authors: quintana fj. Cold Spring Harb Perspect Med. 2019 Jan 2;9(1):a029009. doi: 10.1101/cshperspect.a029009. Cold Spring Harb Perspect Med. 2019. PMID: 29358321 Free PMC article. Review.
HIF-1α-induced xenobiotic transporters promote Th17 responses in Crohn's disease.
Xie A, Robles RJ, Mukherjee S, Zhang H, Feldbrügge L, Csizmadia E, Wu Y, Enjyoji K, Moss AC, Otterbein LE, Quintana FJ, Robson SC, Longhi MS. Xie A, et al. Among authors: quintana fj. J Autoimmun. 2018 Nov;94:122-133. doi: 10.1016/j.jaut.2018.07.022. Epub 2018 Aug 8. J Autoimmun. 2018. PMID: 30098863 Free PMC article.
Effects of Systolic Blood Pressure on Brain Integrity in Multiple Sclerosis.
Dossi DE, Chaves H, Heck ES, Rodriguez Murúa S, Ventrice F, Bakshi R, Quintana FJ, Correale J, Farez MF. Dossi DE, et al. Among authors: quintana fj. Front Neurol. 2018 Jun 25;9:487. doi: 10.3389/fneur.2018.00487. eCollection 2018. Front Neurol. 2018. PMID: 29988562 Free PMC article.
Microglial control of astrocytes in response to microbial metabolites.
Rothhammer V, Borucki DM, Tjon EC, Takenaka MC, Chao CC, Ardura-Fabregat A, de Lima KA, Gutiérrez-Vázquez C, Hewson P, Staszewski O, Blain M, Healy L, Neziraj T, Borio M, Wheeler M, Dragin LL, Laplaud DA, Antel J, Alvarez JI, Prinz M, Quintana FJ. Rothhammer V, et al. Among authors: quintana fj. Nature. 2018 May;557(7707):724-728. doi: 10.1038/s41586-018-0119-x. Epub 2018 May 16. Nature. 2018. PMID: 29769726 Free PMC article.
Detection of aryl hydrocarbon receptor agonists in human samples.
Rothhammer V, Borucki DM, Kenison JE, Hewson P, Wang Z, Bakshi R, Sherr DH, Quintana FJ. Rothhammer V, et al. Among authors: quintana fj. Sci Rep. 2018 Mar 21;8(1):4970. doi: 10.1038/s41598-018-23323-4. Sci Rep. 2018. PMID: 29563571 Free PMC article.
Sample size requirements for one-year treatment effects using deep gray matter volume from 3T MRI in progressive forms of multiple sclerosis.
Kim G, Chu R, Yousuf F, Tauhid S, Stazzone L, Houtchens MK, Stankiewicz JM, Severson C, Kimbrough D, Quintana FJ, Chitnis T, Weiner HL, Healy BC, Bakshi R. Kim G, et al. Among authors: quintana fj. Int J Neurosci. 2017 Nov;127(11):971-980. doi: 10.1080/00207454.2017.1283313. Epub 2017 Feb 2. Int J Neurosci. 2017. PMID: 28100092
A gut feeling about multiple sclerosis.
Quintana FJ, Prinz M. Quintana FJ, et al. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10528-10529. doi: 10.1073/pnas.1714260114. Epub 2017 Sep 25. Proc Natl Acad Sci U S A. 2017. PMID: 28973867 Free PMC article. No abstract available.
Dynamic regulation of serum aryl hydrocarbon receptor agonists in MS.
Rothhammer V, Borucki DM, Garcia Sanchez MI, Mazzola MA, Hemond CC, Regev K, Paul A, Kivisäkk P, Bakshi R, Izquierdo G, Weiner HL, Quintana FJ. Rothhammer V, et al. Among authors: quintana fj. Neurol Neuroimmunol Neuroinflamm. 2017 Jun 16;4(4):e359. doi: 10.1212/NXI.0000000000000359. eCollection 2017 Jul. Neurol Neuroimmunol Neuroinflamm. 2017. PMID: 28642887 Free PMC article.
IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment.
Nirschl CJ, Suárez-Fariñas M, Izar B, Prakadan S, Dannenfelser R, Tirosh I, Liu Y, Zhu Q, Devi KSP, Carroll SL, Chau D, Rezaee M, Kim TG, Huang R, Fuentes-Duculan J, Song-Zhao GX, Gulati N, Lowes MA, King SL, Quintana FJ, Lee YS, Krueger JG, Sarin KY, Yoon CH, Garraway L, Regev A, Shalek AK, Troyanskaya O, Anandasabapathy N. Nirschl CJ, et al. Among authors: quintana fj. Cell. 2017 Jun 29;170(1):127-141.e15. doi: 10.1016/j.cell.2017.06.016. Cell. 2017. PMID: 28666115 Free PMC article.
Role of AHR and HIF-1α in Glioblastoma Metabolism.
Gabriely G, Wheeler MA, Takenaka MC, Quintana FJ. Gabriely G, et al. Among authors: quintana fj. Trends Endocrinol Metab. 2017 Jun;28(6):428-436. doi: 10.1016/j.tem.2017.02.009. Epub 2017 Mar 16. Trends Endocrinol Metab. 2017. PMID: 28318896 Free PMC article. Review.
Bilirubin suppresses Th17 immunity in colitis by upregulating CD39.
Longhi MS, Vuerich M, Kalbasi A, Kenison JE, Yeste A, Csizmadia E, Vaughn B, Feldbrugge L, Mitsuhashi S, Wegiel B, Otterbein L, Moss A, Quintana FJ, Robson SC. Longhi MS, et al. Among authors: quintana fj. JCI Insight. 2017 May 4;2(9):e92791. doi: 10.1172/jci.insight.92791. eCollection 2017 May 4. JCI Insight. 2017. PMID: 28469075 Free PMC article.
Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation.
Rothhammer V, Kenison JE, Tjon E, Takenaka MC, de Lima KA, Borucki DM, Chao CC, Wilz A, Blain M, Healy L, Antel J, Quintana FJ. Rothhammer V, et al. Among authors: quintana fj. Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):2012-2017. doi: 10.1073/pnas.1615413114. Epub 2017 Feb 6. Proc Natl Acad Sci U S A. 2017. PMID: 28167760 Free PMC article.
Dendritic cells in autoimmunity, infections, and cancer.
Quintana FJ. Quintana FJ. Semin Immunopathol. 2017 Feb;39(2):97-98. doi: 10.1007/s00281-016-0618-5. Epub 2017 Jan 16. Semin Immunopathol. 2017. PMID: 28093619 Free PMC article. No abstract available.
Tolerogenic dendritic cells.
Takenaka MC, Quintana FJ. Takenaka MC, et al. Among authors: quintana fj. Semin Immunopathol. 2017 Feb;39(2):113-120. doi: 10.1007/s00281-016-0587-8. Epub 2016 Sep 19. Semin Immunopathol. 2017. PMID: 27646959 Free PMC article. Review.
Interleukin 1β Mediates Intestinal Inflammation in Mice and Patients With Interleukin 10 Receptor Deficiency.
Shouval DS, Biswas A, Kang YH, Griffith AE, Konnikova L, Mascanfroni ID, Redhu NS, Frei SM, Field M, Doty AL, Goldsmith JD, Bhan AK, Loizides A, Weiss B, Yerushalmi B, Yanagi T, Lui X, Quintana FJ, Muise AM, Klein C, Horwitz BH, Glover SC, Bousvaros A, Snapper SB. Shouval DS, et al. Among authors: quintana fj. Gastroenterology. 2016 Dec;151(6):1100-1104. doi: 10.1053/j.gastro.2016.08.055. Epub 2016 Sep 28. Gastroenterology. 2016. PMID: 27693323 Free PMC article.
AHR Activation Is Protective against Colitis Driven by T Cells in Humanized Mice.
Goettel JA, Gandhi R, Kenison JE, Yeste A, Murugaiyan G, Sambanthamoorthy S, Griffith AE, Patel B, Shouval DS, Weiner HL, Snapper SB, Quintana FJ. Goettel JA, et al. Among authors: quintana fj. Cell Rep. 2016 Oct 25;17(5):1318-1329. doi: 10.1016/j.celrep.2016.09.082. Cell Rep. 2016. PMID: 27783946 Free PMC article.
Anti-inflammatory effects of melatonin in multiple sclerosis.
Farez MF, Calandri IL, Correale J, Quintana FJ. Farez MF, et al. Among authors: quintana fj. Bioessays. 2016 Oct;38(10):1016-26. doi: 10.1002/bies.201600018. Epub 2016 Aug 26. Bioessays. 2016. PMID: 27561251 Review.
Regulation of the T Cell Response by CD39.
Takenaka MC, Robson S, Quintana FJ. Takenaka MC, et al. Among authors: quintana fj. Trends Immunol. 2016 Jul;37(7):427-439. doi: 10.1016/j.it.2016.04.009. Epub 2016 May 25. Trends Immunol. 2016. PMID: 27236363 Free PMC article. Review.
Digestion of Chromatin in Apoptotic Cell Microparticles Prevents Autoimmunity.
Sisirak V, Sally B, D'Agati V, Martinez-Ortiz W, Özçakar ZB, David J, Rashidfarrokhi A, Yeste A, Panea C, Chida AS, Bogunovic M, Ivanov II, Quintana FJ, Sanz I, Elkon KB, Tekin M, Yalçınkaya F, Cardozo TJ, Clancy RM, Buyon JP, Reizis B. Sisirak V, et al. Among authors: quintana fj. Cell. 2016 Jun 30;166(1):88-101. doi: 10.1016/j.cell.2016.05.034. Epub 2016 Jun 9. Cell. 2016. PMID: 27293190 Free PMC article.
Alterations of the human gut microbiome in multiple sclerosis.
Jangi S, Gandhi R, Cox LM, Li N, von Glehn F, Yan R, Patel B, Mazzola MA, Liu S, Glanz BL, Cook S, Tankou S, Stuart F, Melo K, Nejad P, Smith K, Topçuolu BD, Holden J, Kivisäkk P, Chitnis T, De Jager PL, Quintana FJ, Gerber GK, Bry L, Weiner HL. Jangi S, et al. Among authors: quintana fj. Nat Commun. 2016 Jun 28;7:12015. doi: 10.1038/ncomms12015. Nat Commun. 2016. PMID: 27352007 Free PMC article.
Tolerogenic nanoparticles inhibit T cell-mediated autoimmunity through SOCS2.
Yeste A, Takenaka MC, Mascanfroni ID, Nadeau M, Kenison JE, Patel B, Tukpah AM, Babon JA, DeNicola M, Kent SC, Pozo D, Quintana FJ. Yeste A, et al. Among authors: quintana fj. Sci Signal. 2016 Jun 21;9(433):ra61. doi: 10.1126/scisignal.aad0612. Sci Signal. 2016. PMID: 27330188 Free article.
Purinergic Signaling as a Regulator of Th17 Cell Plasticity.
Fernández D, Flores-Santibáñez F, Neira J, Osorio-Barrios F, Tejón G, Nuñez S, Hidalgo Y, Fuenzalida MJ, Meza D, Ureta G, Lladser A, Pacheco R, Acuña-Castillo C, Guixé V, Quintana FJ, Bono MR, Rosemblatt M, Sauma D. Fernández D, et al. Among authors: quintana fj. PLoS One. 2016 Jun 20;11(6):e0157889. doi: 10.1371/journal.pone.0157889. eCollection 2016. PLoS One. 2016. PMID: 27322617 Free PMC article.
Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor.
Rothhammer V, Mascanfroni ID, Bunse L, Takenaka MC, Kenison JE, Mayo L, Chao CC, Patel B, Yan R, Blain M, Alvarez JI, Kébir H, Anandasabapathy N, Izquierdo G, Jung S, Obholzer N, Pochet N, Clish CB, Prinz M, Prat A, Antel J, Quintana FJ. Rothhammer V, et al. Among authors: quintana fj. Nat Med. 2016 Jun;22(6):586-97. doi: 10.1038/nm.4106. Epub 2016 May 9. Nat Med. 2016. PMID: 27158906 Free PMC article.
Serum lipid antibodies are associated with cerebral tissue damage in multiple sclerosis.
Bakshi R, Yeste A, Patel B, Tauhid S, Tummala S, Rahbari R, Chu R, Regev K, Kivisäkk P, Weiner HL, Quintana FJ. Bakshi R, et al. Among authors: quintana fj. Neurol Neuroimmunol Neuroinflamm. 2016 Jan 27;3(2):e200. doi: 10.1212/NXI.0000000000000200. eCollection 2016 Apr. Neurol Neuroimmunol Neuroinflamm. 2016. PMID: 26894204 Free PMC article.
System-wide Analysis of the T Cell Response.
Covacu R, Philip H, Jaronen M, Almeida J, Kenison JE, Darko S, Chao CC, Yaari G, Louzoun Y, Carmel L, Douek DC, Efroni S, Quintana FJ. Covacu R, et al. Among authors: quintana fj. Cell Rep. 2016 Mar 22;14(11):2733-44. doi: 10.1016/j.celrep.2016.02.056. Epub 2016 Mar 10. Cell Rep. 2016. PMID: 26972015 Free PMC article.
Achieving Tolerance with Perforin-Secreting Dendritic Cells.
Takenaka MC, Quintana FJ. Takenaka MC, et al. Among authors: quintana fj. Trends Mol Med. 2016 Jan;22(1):3-4. doi: 10.1016/j.molmed.2015.11.008. Epub 2015 Dec 12. Trends Mol Med. 2016. PMID: 26700492 Free PMC article.
The 'Omics' of Amyotrophic Lateral Sclerosis.
Caballero-Hernandez D, Toscano MG, Cejudo-Guillen M, Garcia-Martin ML, Lopez S, Franco JM, Quintana FJ, Roodveldt C, Pozo D. Caballero-Hernandez D, et al. Among authors: quintana fj. Trends Mol Med. 2016 Jan;22(1):53-67. doi: 10.1016/j.molmed.2015.11.001. Epub 2015 Dec 13. Trends Mol Med. 2016. PMID: 26691296 Review.
Control of autoimmune CNS inflammation by astrocytes.
Rothhammer V, Quintana FJ. Rothhammer V, et al. Among authors: quintana fj. Semin Immunopathol. 2015 Nov;37(6):625-38. doi: 10.1007/s00281-015-0515-3. Epub 2015 Jul 30. Semin Immunopathol. 2015. PMID: 26223505 Free PMC article. Review.
Melatonin Contributes to the Seasonality of Multiple Sclerosis Relapses.
Farez MF, Mascanfroni ID, Méndez-Huergo SP, Yeste A, Murugaiyan G, Garo LP, Balbuena Aguirre ME, Patel B, Ysrraelit MC, Zhu C, Kuchroo VK, Rabinovich GA, Quintana FJ, Correale J. Farez MF, et al. Among authors: quintana fj. Cell. 2015 Sep 10;162(6):1338-52. doi: 10.1016/j.cell.2015.08.025. Cell. 2015. PMID: 26359987 Free PMC article.
Fatal autoimmunity in mice reconstituted with human hematopoietic stem cells encoding defective FOXP3.
Goettel JA, Biswas S, Lexmond WS, Yeste A, Passerini L, Patel B, Yang S, Sun J, Ouahed J, Shouval DS, McCann KJ, Horwitz BH, Mathis D, Milford EL, Notarangelo LD, Roncarolo MG, Fiebiger E, Marasco WA, Bacchetta R, Quintana FJ, Pai SY, Klein C, Muise AM, Snapper SB. Goettel JA, et al. Among authors: quintana fj. Blood. 2015 Jun 18;125(25):3886-95. doi: 10.1182/blood-2014-12-618363. Epub 2015 Apr 1. Blood. 2015. PMID: 25833964 Free PMC article.
Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α.
Mascanfroni ID, Takenaka MC, Yeste A, Patel B, Wu Y, Kenison JE, Siddiqui S, Basso AS, Otterbein LE, Pardoll DM, Pan F, Priel A, Clish CB, Robson SC, Quintana FJ. Mascanfroni ID, et al. Among authors: quintana fj. Nat Med. 2015 Jun;21(6):638-46. doi: 10.1038/nm.3868. Epub 2015 May 25. Nat Med. 2015. PMID: 26005855 Free PMC article.
Epitope spreading as an early pathogenic event in pediatric multiple sclerosis.
Quintana FJ, Patel B, Yeste A, Nyirenda M, Kenison J, Rahbari R, Fetco D, Hussain M, O'Mahony J, Magalhaes S, McGowan M, Johnson T, Rajasekharan S, Narayanan S, Arnold DL, Weiner HL, Banwell B, Bar-Or A; Canadian Pediatric Demyelinating Disease Network. Quintana FJ, et al. Neurology. 2014 Dec 9;83(24):2219-26. doi: 10.1212/WNL.0000000000001066. Epub 2014 Nov 7. Neurology. 2014. PMID: 25381299 Free PMC article.
Immunological Relevance of the Coevolution of IDO1 and AHR.
Jaronen M, Quintana FJ. Jaronen M, et al. Among authors: quintana fj. Front Immunol. 2014 Oct 20;5:521. doi: 10.3389/fimmu.2014.00521. eCollection 2014. Front Immunol. 2014. PMID: 25368620 Free PMC article. Review.
Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation.
Mayo L, Trauger SA, Blain M, Nadeau M, Patel B, Alvarez JI, Mascanfroni ID, Yeste A, Kivisäkk P, Kallas K, Ellezam B, Bakshi R, Prat A, Antel JP, Weiner HL, Quintana FJ. Mayo L, et al. Among authors: quintana fj. Nat Med. 2014 Oct;20(10):1147-56. doi: 10.1038/nm.3681. Epub 2014 Sep 14. Nat Med. 2014. PMID: 25216636 Free PMC article.
LeA(H)Rning self-control.
Quintana FJ. Quintana FJ. Cell Res. 2014 Oct;24(10):1155-6. doi: 10.1038/cr.2014.96. Epub 2014 Jul 25. Cell Res. 2014. PMID: 25060701 Free PMC article.
Interleukin-10 receptor signaling in innate immune cells regulates mucosal immune tolerance and anti-inflammatory macrophage function.
Shouval DS, Biswas A, Goettel JA, McCann K, Conaway E, Redhu NS, Mascanfroni ID, Al Adham Z, Lavoie S, Ibourk M, Nguyen DD, Samsom JN, Escher JC, Somech R, Weiss B, Beier R, Conklin LS, Ebens CL, Santos FG, Ferreira AR, Sherlock M, Bhan AK, Müller W, Mora JR, Quintana FJ, Klein C, Muise AM, Horwitz BH, Snapper SB. Shouval DS, et al. Among authors: quintana fj. Immunity. 2014 May 15;40(5):706-19. doi: 10.1016/j.immuni.2014.03.011. Epub 2014 May 1. Immunity. 2014. PMID: 24792912 Free PMC article.
IL-21 induces IL-22 production in CD4+ T cells.
Yeste A, Mascanfroni ID, Nadeau M, Burns EJ, Tukpah AM, Santiago A, Wu C, Patel B, Kumar D, Quintana FJ. Yeste A, et al. Among authors: quintana fj. Nat Commun. 2014 May 6;5:3753. doi: 10.1038/ncomms4753. Nat Commun. 2014. PMID: 24796415 Free PMC article.
[Immunopathology of multiple sclerosis].
Quintana FJ, Pérez-Sánchez S, Farez MF. Quintana FJ, et al. Medicina (B Aires). 2014;74(5):404-10. Medicina (B Aires). 2014. PMID: 25347906 Free article. Review. Spanish.
Aryl hydrocarbon receptor control of adaptive immunity.
Quintana FJ, Sherr DH. Quintana FJ, et al. Pharmacol Rev. 2013 Aug 1;65(4):1148-61. doi: 10.1124/pr.113.007823. Print 2013. Pharmacol Rev. 2013. PMID: 23908379 Free PMC article. Review.
Antigen microarrays for the study of autoimmune diseases.
Yeste A, Quintana FJ. Yeste A, et al. Among authors: quintana fj. Clin Chem. 2013 Jul;59(7):1036-44. doi: 10.1373/clinchem.2012.194423. Epub 2013 Mar 13. Clin Chem. 2013. PMID: 23487172 Review.
Individual and meta-immune networks.
Bransburg-Zabary S, Kenett DY, Dar G, Madi A, Merbl Y, Quintana FJ, Tauber AI, Cohen IR, Ben-Jacob E. Bransburg-Zabary S, et al. Among authors: quintana fj. Phys Biol. 2013 Apr;10(2):025003. doi: 10.1088/1478-3975/10/2/025003. Epub 2013 Mar 15. Phys Biol. 2013. PMID: 23492831
Induction and molecular signature of pathogenic TH17 cells.
Lee Y, Awasthi A, Yosef N, Quintana FJ, Xiao S, Peters A, Wu C, Kleinewietfeld M, Kunder S, Hafler DA, Sobel RA, Regev A, Kuchroo VK. Lee Y, et al. Among authors: quintana fj. Nat Immunol. 2012 Oct;13(10):991-9. doi: 10.1038/ni.2416. Epub 2012 Sep 9. Nat Immunol. 2012. PMID: 22961052 Free PMC article.
Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice.
Xiao S, Brooks CR, Zhu C, Wu C, Sweere JM, Petecka S, Yeste A, Quintana FJ, Ichimura T, Sobel RA, Bonventre JV, Kuchroo VK. Xiao S, et al. Among authors: quintana fj. Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12105-10. doi: 10.1073/pnas.1120914109. Epub 2012 Jul 5. Proc Natl Acad Sci U S A. 2012. PMID: 22773818 Free PMC article.
The innate immune system in demyelinating disease.
Mayo L, Quintana FJ, Weiner HL. Mayo L, et al. Among authors: quintana fj. Immunol Rev. 2012 Jul;248(1):170-87. doi: 10.1111/j.1600-065X.2012.01135.x. Immunol Rev. 2012. PMID: 22725961 Free PMC article. Review.
Antigen microarrays identify CNS-produced autoantibodies in RRMS.
Quintana FJ, Farez MF, Izquierdo G, Lucas M, Cohen IR, Weiner HL. Quintana FJ, et al. Neurology. 2012 Feb 21;78(8):532-9. doi: 10.1212/WNL.0b013e318247f9f3. Epub 2012 Jan 18. Neurology. 2012. PMID: 22262743 Free PMC article.
Overexpression of the Ctla-4 isoform lacking exons 2 and 3 causes autoimmunity.
Liu SM, Sutherland AP, Zhang Z, Rainbow DB, Quintana FJ, Paterson AM, Sharpe AH, Oukka M, Wicker LS, Kuchroo VK. Liu SM, et al. Among authors: quintana fj. J Immunol. 2012 Jan 1;188(1):155-62. doi: 10.4049/jimmunol.1102042. Epub 2011 Nov 28. J Immunol. 2012. PMID: 22124121 Free PMC article.
The HSP60 immune system network.
Quintana FJ, Cohen IR. Quintana FJ, et al. Trends Immunol. 2011 Feb;32(2):89-95. doi: 10.1016/j.it.2010.11.001. Epub 2010 Dec 8. Trends Immunol. 2011. PMID: 21145789 Review.
T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice.
Rodriguez-Manzanet R, Sanjuan MA, Wu HY, Quintana FJ, Xiao S, Anderson AC, Weiner HL, Green DR, Kuchroo VK. Rodriguez-Manzanet R, et al. Among authors: quintana fj. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8706-11. doi: 10.1073/pnas.0910359107. Epub 2010 Apr 5. Proc Natl Acad Sci U S A. 2010. PMID: 20368430 Free PMC article.
Oral administration of OKT3 monoclonal antibody to human subjects induces a dose-dependent immunologic effect in T cells and dendritic cells.
Ilan Y, Zigmond E, Lalazar G, Dembinsky A, Ben Ya'acov A, Hemed N, Kasis I, Axelrod E, Zolotarov L, Klein A, El Haj M, Gandhi R, Baecher-Allan C, Wu H, Murugaiyan G, Kivisakk P, Farez MF, Quintana FJ, Khoury SJ, Weiner HL. Ilan Y, et al. Among authors: quintana fj. J Clin Immunol. 2010 Jan;30(1):167-77. doi: 10.1007/s10875-009-9323-7. Epub 2009 Sep 16. J Clin Immunol. 2010. PMID: 19756989 Free PMC article. Clinical Trial.
Organization of the autoantibody repertoire in healthy newborns and adults revealed by system level informatics of antigen microarray data.
Madi A, Hecht I, Bransburg-Zabary S, Merbl Y, Pick A, Zucker-Toledano M, Quintana FJ, Tauber AI, Cohen IR, Ben-Jacob E. Madi A, et al. Among authors: quintana fj. Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14484-9. doi: 10.1073/pnas.0901528106. Epub 2009 Aug 10. Proc Natl Acad Sci U S A. 2009. PMID: 19667184 Free PMC article.
Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway.
Espinosa A, Dardalhon V, Brauner S, Ambrosi A, Higgs R, Quintana FJ, Sjöstrand M, Eloranta ML, Ní Gabhann J, Winqvist O, Sundelin B, Jefferies CA, Rozell B, Kuchroo VK, Wahren-Herlenius M. Espinosa A, et al. Among authors: quintana fj. J Exp Med. 2009 Aug 3;206(8):1661-71. doi: 10.1084/jem.20090585. Epub 2009 Jul 27. J Exp Med. 2009. PMID: 19635858 Free PMC article.
Environmental control of Th17 differentiation.
Quintana FJ, Weiner HL. Quintana FJ, et al. Eur J Immunol. 2009 Mar;39(3):655-7. doi: 10.1002/eji.200839198. Eur J Immunol. 2009. PMID: 19283716 Free PMC article.
Regulatory T cells and immune computation.
Quintana FJ, Cohen IR. Quintana FJ, et al. Eur J Immunol. 2008 Apr;38(4):903-7. doi: 10.1002/eji.200838143. Eur J Immunol. 2008. PMID: 18395856 Free article.
232 results