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GRB7 protein over-expression and clinical outcome in breast cancer.
Ramsey B, Bai T, Hanlon Newell A, Troxell M, Park B, Olson S, Keenan E, Luoh SW. Ramsey B, et al. Breast Cancer Res Treat. 2011 Jun;127(3):659-69. doi: 10.1007/s10549-010-1010-0. Epub 2010 Jul 16. Breast Cancer Res Treat. 2011. PMID: 20635137
The growth factor receptor-bound protein-7 gene (GRB7) encodes a multi-domain signal transduction molecule. The purpose of this study was to examine the clinical significance of GRB7 protein expression in human breast cancer. ...GRB7 protein over-expression i …
The growth factor receptor-bound protein-7 gene (GRB7) encodes a multi-domain signal transduction molecule. The purpose of this study …
GRB7 dependent proliferation of basal-like, HER-2 positive human breast cancer cell lines is mediated in part by HER-1 signaling.
Luoh SW, Wagoner W, Wang X, Hu Z, Lai X, Chin K, Sears R, Ramsey E. Luoh SW, et al. Mol Carcinog. 2019 May;58(5):699-707. doi: 10.1002/mc.22963. Epub 2019 Jan 28. Mol Carcinog. 2019. PMID: 30604896 Free PMC article.
GRB7 gene encodes a multi-domain signal transduction molecule and is part of the core of the HER-2 amplicon. GRB7 is commonly co-amplified and overexpressed with HER-2 in human breast cancer. This study addresses the role of GRB7 in HER-2 positive human breas …
GRB7 gene encodes a multi-domain signal transduction molecule and is part of the core of the HER-2 amplicon. GRB7 is commonly …
HER-2 gene amplification in human breast cancer without concurrent HER-2 over-expression.
Luoh SW, Ramsey B, Hanlon Newell A, Troxell M, Hu Z, Chin K, Spellman P, Olson S, Keenan E. Luoh SW, et al. Springerplus. 2013 Aug 15;2:386. doi: 10.1186/2193-1801-2-386. eCollection 2013. Springerplus. 2013. PMID: 24102037 Free PMC article.
The growth factor receptor-bound protein-7 (GRB7) gene is in close proximity to HER-2 on chromosome 17q11-12 and codes a signal transduction molecule shown to be an independent adverse marker in breast cancer. METHODS: HER-2 and GRB7 protein expression from 613 froz …
The growth factor receptor-bound protein-7 (GRB7) gene is in close proximity to HER-2 on chromosome 17q11-12 and codes a signal trans …