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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1960 1
1962 1
1965 39
1966 191
1967 217
1968 271
1969 288
1970 356
1971 378
1972 476
1973 572
1974 646
1975 940
1976 1248
1977 1253
1978 1478
1979 1801
1980 2081
1981 2301
1982 2580
1983 3093
1984 2947
1985 3573
1986 3953
1987 4497
1988 4585
1989 5792
1990 6987
1991 7499
1992 8110
1993 8988
1994 10799
1995 11859
1996 11640
1997 12113
1998 12949
1999 14136
2000 14474
2001 15920
2002 16752
2003 18436
2004 20553
2005 17865
2006 13172
2007 13799
2008 14861
2009 16046
2010 17269
2011 18772
2012 20088
2013 22150
2014 23592
2015 25088
2016 25905
2017 26786
2018 27609
2019 29553
2020 32216
2021 32172
2022 30284
2023 28185
2024 28655
2025 97

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640,893 results

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Page 1
A simplified guide to randomized controlled trials.
Bhide A, Shah PS, Acharya G. Bhide A, et al. Acta Obstet Gynecol Scand. 2018 Apr;97(4):380-387. doi: 10.1111/aogs.13309. Epub 2018 Feb 27. Acta Obstet Gynecol Scand. 2018. PMID: 29377058 Free article. Review.
A randomized controlled trial is a prospective, comparative, quantitative study/experiment performed under controlled conditions with random allocation of interventions to comparison groups. ...Therefore, randomized controlled trials …
A randomized controlled trial is a prospective, comparative, quantitative study/experiment performed under controlle …
Key concepts of clinical trials: a narrative review.
Umscheid CA, Margolis DJ, Grossman CE. Umscheid CA, et al. Postgrad Med. 2011 Sep;123(5):194-204. doi: 10.3810/pgm.2011.09.2475. Postgrad Med. 2011. PMID: 21904102 Free PMC article. Review.
However, clinical trials also have the potential to pose unknown risks to their participants, and biased knowledge extracted from flawed clinical trials may lead to the inadvertent harm of patients. ...This narrative review is based on a course in c …
However, clinical trials also have the potential to pose unknown risks to their participants, and biased knowledge extracted f …
Re-inventing the randomized controlled trial in medical oncology: The registry-based trial.
Foroughi S, Wong HL, Gately L, Lee M, Simons K, Tie J, Burgess AW, Gibbs P. Foroughi S, et al. Asia Pac J Clin Oncol. 2018 Dec;14(6):365-373. doi: 10.1111/ajco.12992. Epub 2018 Jun 26. Asia Pac J Clin Oncol. 2018. PMID: 29947051 Review.
Much of this progress has resulted from the serial testing of promising treatment strategies, typically using prospective randomized controlled trials to compare outcomes achieved with the new approach versus the current standard(s) of care. ...These question …
Much of this progress has resulted from the serial testing of promising treatment strategies, typically using prospective randomized …
Clinical hypertension research tools: the randomized controlled clinical trial.
Lackland DT, Woolson RF. Lackland DT, et al. J Clin Hypertens (Greenwich). 2006 Jun;8(6):427-31; quiz 432-3. doi: 10.1111/j.1524-6175.2006.04721.x. J Clin Hypertens (Greenwich). 2006. PMID: 16760682 Free PMC article. Review.
The randomized clinical trial is used in hypertension research as a primary mode for evaluating new, promising therapies. Herein, the authors provide an overview of design features of clinical trials, particularly those useful for designing a hy …
The randomized clinical trial is used in hypertension research as a primary mode for evaluating new, promising therapie …
The primary outcome measure and its importance in clinical trials.
Andrade C. Andrade C. J Clin Psychiatry. 2015 Oct;76(10):e1320-3. doi: 10.4088/JCP.15f10377. J Clin Psychiatry. 2015. PMID: 26528658 Free article. Review.
This article discusses the setting of the primary outcome measure, the need for it, the increased risk of false-positive and false-negative errors in secondary outcome results, how to regard articles that do not state the primary outcome, how to interpret results when secondary o …
This article discusses the setting of the primary outcome measure, the need for it, the increased risk of false-positive and false-negative …
Randomized controlled trials: what are they and who needs them?
Pihlstrom BL, Curran AE, Voelker HT, Kingman A. Pihlstrom BL, et al. Periodontol 2000. 2012 Jun;59(1):14-31. doi: 10.1111/j.1600-0757.2011.00439.x. Periodontol 2000. 2012. PMID: 22507057 Review.
Well-designed randomized controlled trials are conceptually simple but deceptively complex to design, implement and translate into clinical practice. Randomized controlled trials are fundamentally different from observational cl …
Well-designed randomized controlled trials are conceptually simple but deceptively complex to design, implement and tra …
The randomized clinical trial.
Budsberg SC. Budsberg SC. Vet Surg. 1991 Sep-Oct;20(5):326-8. doi: 10.1111/j.1532-950x.1991.tb01278.x. Vet Surg. 1991. PMID: 1962417 Review.
Randomized clinical trials were developed to eliminate biases inherent in clinical medicine. Six types of bias that can occur during patient selection and treatment allocation and in the collection and analysis of the data have been identified. A varia …
Randomized clinical trials were developed to eliminate biases inherent in clinical medicine. Six types of bias t …
Randomized controlled trials.
McCarthy CM. McCarthy CM. Plast Reconstr Surg. 2011 Apr;127(4):1707-1712. doi: 10.1097/PRS.0b013e31820da3eb. Plast Reconstr Surg. 2011. PMID: 21460678
According to this classification, the randomized clinical trial is the most effective way to determine whether a cause-and-effect relationship exists between an intervention and a predefined outcome. The basic principles of clinical trial design …
According to this classification, the randomized clinical trial is the most effective way to determine whether a cause- …
640,893 results
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