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Page 1
A simplified guide to randomized controlled trials.
Bhide A, Shah PS, Acharya G. Bhide A, et al. Acta Obstet Gynecol Scand. 2018 Apr;97(4):380-387. doi: 10.1111/aogs.13309. Epub 2018 Feb 27. Acta Obstet Gynecol Scand. 2018. PMID: 29377058 Free article. Review.
The randomized controlled trial is the most rigorous and robust research method of determining whether a cause-effect relation exists between an intervention and an outcome. High-quality evidence can be generated by performing an randomized controll …
The randomized controlled trial is the most rigorous and robust research method of determining whether a cause-effect r …
Cluster randomized controlled trials.
Puffer S, Torgerson DJ, Watson J. Puffer S, et al. J Eval Clin Pract. 2005 Oct;11(5):479-83. doi: 10.1111/j.1365-2753.2005.00568.x. J Eval Clin Pract. 2005. PMID: 16164589
Cluster randomized controlled trial (RCT), in which groups or clusters of individuals rather than individuals themselves are randomized, are increasingly common. ...
Cluster randomized controlled trial (RCT), in which groups or clusters of individuals rather than individuals themselve …
Key concepts of clinical trials: a narrative review.
Umscheid CA, Margolis DJ, Grossman CE. Umscheid CA, et al. Postgrad Med. 2011 Sep;123(5):194-204. doi: 10.3810/pgm.2011.09.2475. Postgrad Med. 2011. PMID: 21904102 Free PMC article. Review.
This narrative review is based on a course in clinical trials developed by one of the authors (DJM), and is supplemented by a PubMed search predating January 2011 using the keywords "randomized controlled trial," "patient/clinical research," "ethics," "phase …
This narrative review is based on a course in clinical trials developed by one of the authors (DJM), and is supplemented by a PubMed search …
Stepped wedge cluster randomized controlled trial designs: a review of reporting quality and design features.
Grayling MJ, Wason JM, Mander AP. Grayling MJ, et al. Trials. 2017 Jan 21;18(1):33. doi: 10.1186/s13063-017-1783-0. Trials. 2017. PMID: 28109321 Free PMC article. Review.
BACKGROUND: The stepped wedge (SW) cluster randomized controlled trial (CRCT) design is being used with increasing frequency. However, there is limited published research on the quality of reporting of SW-CRCTs. ...
BACKGROUND: The stepped wedge (SW) cluster randomized controlled trial (CRCT) design is being used with increasing freq …
Planning a cluster randomized controlled trial: methodological issues.
Christie J, O'Halloran P, Stevenson M. Christie J, et al. Nurs Res. 2009 Mar-Apr;58(2):128-34. doi: 10.1097/NNR.0b013e3181900cb5. Nurs Res. 2009. PMID: 19289934 Review.
BACKGROUND: The standard approach in a randomized controlled trial (RCT) is to randomize individuals to intervention and control groups. ...
BACKGROUND: The standard approach in a randomized controlled trial (RCT) is to randomize individuals to intervention an …
Improving the reporting of pragmatic trials: an extension of the CONSORT statement.
Zwarenstein M, Treweek S, Gagnier JJ, Altman DG, Tunis S, Haynes B, Oxman AD, Moher D; CONSORT group; Pragmatic Trials in Healthcare (Practihc) group. Zwarenstein M, et al. BMJ. 2008 Nov 11;337:a2390. doi: 10.1136/bmj.a2390. BMJ. 2008. PMID: 19001484 Free PMC article.
A pragmatic trial (a term first used in 1967 by Schwartz and Lellouch) can be broadly defined as a randomised controlled trial whose purpose is to inform decisions about practice. This extension of the CONSORT statement is intended to improve the reporting of …
A pragmatic trial (a term first used in 1967 by Schwartz and Lellouch) can be broadly defined as a randomised controlled tr …
848,537 results
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