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Did you mean easily releasable pool (12 results)?
The readily releasable pool of synaptic vesicles.
Kaeser PS, Regehr WG. Kaeser PS, et al. Curr Opin Neurobiol. 2017 Apr;43:63-70. doi: 10.1016/j.conb.2016.12.012. Epub 2017 Jan 16. Curr Opin Neurobiol. 2017. PMID: 28103533 Free PMC article. Review.
Each presynaptic bouton is densely packed with many vesicles, only a small fraction of which are available for immediate release. These vesicles constitute the readily releasable pool (RRP). The RRP size, and the probability of release of each vesicle within …
Each presynaptic bouton is densely packed with many vesicles, only a small fraction of which are available for immediate release. These vesi …
The readily-releasable pool dynamically regulates multivesicular release.
Vaden JH, Banumurthy G, Gusarevich ES, Overstreet-Wadiche L, Wadiche JI. Vaden JH, et al. Elife. 2019 Jul 31;8:e47434. doi: 10.7554/eLife.47434. Elife. 2019. PMID: 31364987 Free PMC article.
However, using mouse brain slices, we now demonstrate that the number of vesicles released is regulated by the size of the readily-releasable pool, upstream of vesicle release probability. Our results point to a model wherein protein kinase A and its vesicle- …
However, using mouse brain slices, we now demonstrate that the number of vesicles released is regulated by the size of the readily- …
Considerations for Measuring Activity-Dependence of Recruitment of Synaptic Vesicles to the Readily Releasable Pool.
Wesseling JF. Wesseling JF. Front Synaptic Neurosci. 2019 Nov 20;11:32. doi: 10.3389/fnsyn.2019.00032. eCollection 2019. Front Synaptic Neurosci. 2019. PMID: 31824292 Free PMC article. Review.
One important factor is the timing of recruitment of synaptic vesicles to a readily-releasable pool. A number of studies have concluded that activity and/or residual Ca(2+) can accelerate the mechanism, but alternative explanations for some of the evidence ha …
One important factor is the timing of recruitment of synaptic vesicles to a readily-releasable pool. A number of studie …
Estimation of the Readily Releasable Synaptic Vesicle Pool at the Drosophila Larval Neuromuscular Junction.
Goel P, Li X, Dickman D. Goel P, et al. Bio Protoc. 2019 Jan 5;9(1):e3127. doi: 10.21769/BioProtoc.3127. Bio Protoc. 2019. PMID: 30761328 Free PMC article.
A small proportion of synaptic vesicles are docked and primed for immediate fusion upon synaptic stimulation, which together comprise the readily releasable pool. The size of the readily releasable pool is an important property of synapse …
A small proportion of synaptic vesicles are docked and primed for immediate fusion upon synaptic stimulation, which together comprise the …
Formation, stabilisation and fusion of the readily releasable pool of secretory vesicles.
Sørensen JB. Sørensen JB. Pflugers Arch. 2004 Jul;448(4):347-62. doi: 10.1007/s00424-004-1247-8. Epub 2004 Mar 2. Pflugers Arch. 2004. PMID: 14997396 Review.
Vesicles in this readily releasable pool are characterized by very low release rate constants at the resting cytosolic [Ca2+] ([Ca2+]i) and very high release rate constants at stimulated [Ca2+]i. ...Finally, I review recent evidence that the soluble N-ethylma …
Vesicles in this readily releasable pool are characterized by very low release rate constants at the resting cytosolic …
Intersectin-1 enhances calcium-dependent replenishment of the readily releasable pool of synaptic vesicles during development.
Yang YM, Fekete A, Arsenault J, Sengar AS, Aitoubah J, Grande G, Li A, Salter EW, Wang A, Mark MD, Herlitze S, Egan SE, Salter MW, Wang LY. Yang YM, et al. J Physiol. 2025 Oct;603(20):6185-6206. doi: 10.1113/JP286462. Epub 2024 Oct 9. J Physiol. 2025. PMID: 39383250 Free PMC article.
Loss of function of Itsn1 did not alter presynaptic action potentials, Ca(2+) entry via voltage-gated Ca(2+) channels (VGCCs), transmitter release or short-term depression (STD) induced by depletion of SVs in the readily releasable pool (RRP) in either age gr …
Loss of function of Itsn1 did not alter presynaptic action potentials, Ca(2+) entry via voltage-gated Ca(2+) channels (VGCCs), transmitter r …
Outside-in regulation of the readily releasable pool of synaptic vesicles by alpha2delta-1.
Martínez San Segundo P, Terni B, Burgueño J, Monroy X, Dordal A, Merlos M, Llobet A. Martínez San Segundo P, et al. FASEB J. 2020 Jan;34(1):1362-1377. doi: 10.1096/fj.201901551R. Epub 2019 Nov 30. FASEB J. 2020. PMID: 31914622
The readily releasable pool (RRP) of synaptic vesicles is a key determinant of phasic neurotransmission. ...
The readily releasable pool (RRP) of synaptic vesicles is a key determinant of phasic neurotransmission. ...
A Reduction in the Readily Releasable Vesicle Pool Impairs GABAergic Inhibition in the Hippocampus after Blood-Brain Barrier Dysfunction.
Lippmann K. Lippmann K. Int J Mol Sci. 2024 Jun 22;25(13):6862. doi: 10.3390/ijms25136862. Int J Mol Sci. 2024. PMID: 38999971 Free PMC article.
Furthermore, the paired-pulse ratio of evoked GABA release was increased at 100 Hz, and train stimulations with 100 Hz revealed that the readily releasable pool (RRP), usually assumed to correspond to the number of tightly docked presynaptic vesicles, is redu …
Furthermore, the paired-pulse ratio of evoked GABA release was increased at 100 Hz, and train stimulations with 100 Hz revealed that the …
Estimating the Readily-Releasable Vesicle Pool Size at Synaptic Connections in the Neocortex.
Barros-Zulaica N, Rahmon J, Chindemi G, Perin R, Markram H, Muller E, Ramaswamy S. Barros-Zulaica N, et al. Front Synaptic Neurosci. 2019 Oct 15;11:29. doi: 10.3389/fnsyn.2019.00029. eCollection 2019. Front Synaptic Neurosci. 2019. PMID: 31680928 Free PMC article.
In this study we present a novel method to estimate the number of release sites per synapse, also known as the size of the readily releasable pool (N(RRP)), from paired whole-cell recordings of connections between layer 5 thick tufted pyramidal cell (L5_TTPC) …
In this study we present a novel method to estimate the number of release sites per synapse, also known as the size of the readily …
Measuring the Readily Releasable Synaptic Vesicle Pool at the Drosophila Larval Neuromuscular Junction.
Wang T, Frank CA. Wang T, et al. Cold Spring Harb Protoc. 2025 May 5;2025(5):pdb.prot108425. doi: 10.1101/pdb.prot108425. Cold Spring Harb Protoc. 2025. PMID: 38688540 Free PMC article.
This calcium influx triggers the fusion of vesicles from the readily releasable vesicle pool (RRP) that are ready for immediate release. Two key presynaptic cellular mechanisms are essential for PHP's induction and maintenance. ...
This calcium influx triggers the fusion of vesicles from the readily releasable vesicle pool (RRP) that are ready for i …
833 results