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Year Number of Results
2001 2
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48 results

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Page 1
The impact of transcutaneous electrical acustimulation (TEA) on rectal distension-induced pain in patients with irritable bowel syndrome (IBS)-A study to determine the optimal TEA delivery modalities and effects on rectal sensation and autonomic function.
Nojkov B, Burnett C, Watts L, Yin J, Ali K, Zhao T, Gong S, Miller C, Habrowski M, Chey WD, Chen JDZ. Nojkov B, et al. Neurogastroenterol Motil. 2024 Jul;36(7):e14799. doi: 10.1111/nmo.14799. Epub 2024 Apr 26. Neurogastroenterol Motil. 2024. PMID: 38671591 Clinical Trial.
BACKGROUND: Treatment options for abdominal pain in IBS are inadequate. TEA was reported effective treatment of disorders of gut-brain interaction but its mechanism of action and optimal delivery method for treating pain in IBS are unknown. This study …
BACKGROUND: Treatment options for abdominal pain in IBS are inadequate. TEA was reported effective treatment of disorders of g …
Somatic referral of visceral sensations and rectal sensory threshold for pain in children with functional gastrointestinal disorders.
Faure C, Wieckowska A. Faure C, et al. J Pediatr. 2007 Jan;150(1):66-71. doi: 10.1016/j.jpeds.2006.08.072. J Pediatr. 2007. PMID: 17188617
The projections of sensations induced by rectal distension, the rectal sensory threshold for pain (RSTP) and the diagnostic value of RSTP measurements were measured. ...At 30.8 mm Hg, the 5th percentile for the control subjects, the RSTP had a sensitiv …
The projections of sensations induced by rectal distension, the rectal sensory threshold for pain (RSTP) and the …
[Rectal barostat in irritable bowel syndrome].
Defilippi G C, Quera P R, Madrid S AM, Defilippi C C, Valenzuela E J. Defilippi G C, et al. Rev Med Chil. 2006 Dec;134(12):1524-9. doi: 10.4067/s0034-98872006001200005. Epub 2007 Jan 24. Rev Med Chil. 2006. PMID: 17277868 Free article. Spanish.
Visceral hypersensitivity was defined as a pain threshold under 38 mmHg. RESULTS: Only 26% of IBS patients had visceral hypersensitivity (16% and 43% of patients with IBS and constipation and IBS and diarrhea or alternating symptoms, respectivel …
Visceral hypersensitivity was defined as a pain threshold under 38 mmHg. RESULTS: Only 26% of IBS patients had visceral …
Novel techniques to study visceral hypersensitivity in irritable bowel syndrome.
Truong TT, Naliboff BD, Chang L. Truong TT, et al. Curr Gastroenterol Rep. 2008 Aug;10(4):369-78. doi: 10.1007/s11894-008-0071-2. Curr Gastroenterol Rep. 2008. PMID: 18627648 Review.
Visceral hypersensitivity has emerged as a key hypothesis in explaining the painful symptoms of irritable bowel syndrome (IBS), and it has been proposed as a "biologic marker" for the condition. Visceral hypersensitivity can be influenced by peripheral and central mechanis …
Visceral hypersensitivity has emerged as a key hypothesis in explaining the painful symptoms of irritable bowel syndrome (IBS), and i …
Contributions of pain sensitivity and colonic motility to IBS symptom severity and predominant bowel habits.
Kanazawa M, Palsson OS, Thiwan SI, Turner MJ, van Tilburg MA, Gangarosa LM, Chitkara DK, Fukudo S, Drossman DA, Whitehead WE. Kanazawa M, et al. Am J Gastroenterol. 2008 Oct;103(10):2550-61. doi: 10.1111/j.1572-0241.2008.02066.x. Epub 2008 Aug 5. Am J Gastroenterol. 2008. PMID: 18684175 Free PMC article.
OBJECTIVES: Irritable bowel syndrome (IBS) patients show pain hypersensitivity and hypercontractility in response to colonic or rectal distention. ...Average barostat bag volume at baseline was higher (muscle tone lower) in HC compared with IBS- …
OBJECTIVES: Irritable bowel syndrome (IBS) patients show pain hypersensitivity and hypercontractility in response to colonic o …
Visceral hypersensitivity in irritable bowel syndrome: evidence for involvement of serotonin metabolism--a preliminary study.
Keszthelyi D, Troost FJ, Jonkers DM, van Eijk HM, Dekker J, Buurman WA, Masclee AA. Keszthelyi D, et al. Neurogastroenterol Motil. 2015 Aug;27(8):1127-37. doi: 10.1111/nmo.12600. Epub 2015 May 31. Neurogastroenterol Motil. 2015. PMID: 26031193 Clinical Trial.
KEY RESULTS: 5-HTP induces rectal allodynia in a significant number of healthy controls; IBS patients exhibit lowered pain thresholds in both placebo and 5-HTP conditions. 5-HTP induces rectal hyperalgesia in hypersensitive but not in non-hypersensitiv …
KEY RESULTS: 5-HTP induces rectal allodynia in a significant number of healthy controls; IBS patients exhibit lowered pain …
Evolution of visceral sensitivity in patients with irritable bowel syndrome.
Poitras P, Riberdy Poitras M, Plourde V, Boivin M, Verrier P. Poitras P, et al. Dig Dis Sci. 2002 Apr;47(4):914-20. doi: 10.1023/a:1014729125428. Dig Dis Sci. 2002. PMID: 11991628
The pain threshold to rectal distension was measured by a barostat programmed for phasic ascending distensions. ...In conclusion, visceral hypersensitivity appeared as a stable biological defect over a 10- to 12-week period during clinically-effective …
The pain threshold to rectal distension was measured by a barostat programmed for phasic ascending distensions. …
Does meal ingestion enhance sensitivity of visceroperception assessment in irritable bowel syndrome?
Ludidi S, Conchillo JM, Keszthelyi D, Koning CJ, Vanhoutvin SA, Lindsey PJ, Leufkens AM, Kruimel JW, Jonkers DM, Masclee AA. Ludidi S, et al. Neurogastroenterol Motil. 2012 Jan;24(1):47-53, e3. doi: 10.1111/j.1365-2982.2011.01802.x. Epub 2011 Nov 2. Neurogastroenterol Motil. 2012. PMID: 22050206
Urge, discomfort, and pain were scored on a visual analog scale. Furthermore, percentages of hypersensitive IBS patients and HC were calculated and dynamic rectal compliance was assessed. ...The HC showed increased scores for urge and pain only. Rec …
Urge, discomfort, and pain were scored on a visual analog scale. Furthermore, percentages of hypersensitive IBS patients and H …
The effects of sildenafil on rectal sensitivity and tone in patients with the irritable bowel syndrome.
Gonçalves de Medeiros MT, de Oliveira RB, dos Santos AA, de Leopoldino DM, Lima MC, Nobre RA, Nobre e Souza MÂ. Gonçalves de Medeiros MT, et al. Aliment Pharmacol Ther. 2012 Mar;35(5):577-86. doi: 10.1111/j.1365-2036.2011.04977.x. Epub 2012 Jan 10. Aliment Pharmacol Ther. 2012. PMID: 22229478 Clinical Trial.
Five IBS patients had pain threshold lower than controls 95% confidence interval (hypersensitive). ...CONCLUSIONS: Rectal relaxation following dosing with sildenafil 50 mg increased the first desire to defecate threshold in IBS as a whole …
Five IBS patients had pain threshold lower than controls 95% confidence interval (hypersensitive). ...CONCLUSIONS: R …
Visceral sensitivity remains stable over time in patients with irritable bowel syndrome, but with individual fluctuations.
Josefsson A, Rosendahl A, Jerlstad P, Näslin G, Törnblom H, Simrén M. Josefsson A, et al. Neurogastroenterol Motil. 2019 Jul;31(7):e13603. doi: 10.1111/nmo.13603. Epub 2019 Apr 22. Neurogastroenterol Motil. 2019. PMID: 31012215
BACKGROUND: Visceral hypersensitivity in irritable bowel syndrome (IBS), measured with rectal balloon distensions, using a barostat, has been suggested to be a phenomenon that is reduced due to habituation at repeated investigations. We investigated the stabi …
BACKGROUND: Visceral hypersensitivity in irritable bowel syndrome (IBS), measured with rectal balloon distensions, using a …
48 results