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Showing results for reddington 2013 genome biol
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Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes.
Reddington JP, Perricone SM, Nestor CE, Reichmann J, Youngson NA, Suzuki M, Reinhardt D, Dunican DS, Prendergast JG, Mjoseng H, Ramsahoye BH, Whitelaw E, Greally JM, Adams IR, Bickmore WA, Meehan RR. Reddington JP, et al. Genome Biol. 2013 Mar 25;14(3):R25. doi: 10.1186/gb-2013-14-3-r25. Genome Biol. 2013. PMID: 23531360 Free PMC article.
However, whether this role of DNA methylation is important in the context of transcriptional regulation is unclear. RESULTS: By genome-wide mapping of the Polycomb Repressive Complex 2-signature histone mark, H3K27me3, in severely DNA hypomethylated mouse somatic cells, we …
However, whether this role of DNA methylation is important in the context of transcriptional regulation is unclear. RESULTS: By genome