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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
1973 2
1974 1
1975 5
1976 4
1977 2
1978 2
1979 6
1980 2
1981 3
1982 6
1983 6
1984 10
1985 5
1986 6
1987 10
1988 3
1989 3
1990 6
1991 7
1992 13
1993 26
1994 23
1995 23
1996 30
1997 38
1998 43
1999 46
2000 67
2001 91
2002 88
2003 117
2004 132
2005 158
2006 168
2007 203
2008 206
2009 190
2010 273
2011 292
2012 329
2013 372
2014 388
2015 360
2016 351
2017 352
2018 403
2019 459
2020 480
2021 494
2022 384
2023 89
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5,939 results
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Page 1
ROS function in redox signaling and oxidative stress.
Schieber M, Chandel NS. Schieber M, et al. Curr Biol. 2014 May 19;24(10):R453-62. doi: 10.1016/j.cub.2014.03.034. Curr Biol. 2014. PMID: 24845678 Free PMC article. Review.
Oxidative stress has been linked to a myriad of pathologies. However, elevated ROS also act as signaling molecules in the maintenance of physiological functions--a process termed redox biology. ...Redox biology involves a small increase in ROS levels t …
Oxidative stress has been linked to a myriad of pathologies. However, elevated ROS also act as signaling molecules in the main …
Oxidative stress: a concept in redox biology and medicine.
Sies H. Sies H. Redox Biol. 2015;4:180-3. doi: 10.1016/j.redox.2015.01.002. Epub 2015 Jan 3. Redox Biol. 2015. PMID: 25588755 Free PMC article. Review.
The fundamental importance of linking redox shifts to phosphorylation/dephosphorylation signaling is being more fully appreciated, thanks to major advances in methodology. ...This can lead to indiscriminate use of the term, oxidative stress, without clear relation t …
The fundamental importance of linking redox shifts to phosphorylation/dephosphorylation signaling is being more fully apprecia …
Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress.
Sies H. Sies H. Redox Biol. 2017 Apr;11:613-619. doi: 10.1016/j.redox.2016.12.035. Epub 2017 Jan 5. Redox Biol. 2017. PMID: 28110218 Free PMC article. Review.
Hydrogen peroxide emerged as major redox metabolite operative in redox sensing, signaling and redox regulation. ...What are the metabolic sources and sinks of H(2)O(2)? What is the role of H(2)O(2) in redox signaling and oxidative stress? …
Hydrogen peroxide emerged as major redox metabolite operative in redox sensing, signaling and redox regulation. …
Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling.
Ray PD, Huang BW, Tsuji Y. Ray PD, et al. Cell Signal. 2012 May;24(5):981-90. doi: 10.1016/j.cellsig.2012.01.008. Epub 2012 Jan 20. Cell Signal. 2012. PMID: 22286106 Free PMC article. Review.
Paradoxically, accumulating evidence indicates that ROS also serve as critical signaling molecules in cell proliferation and survival. While there is a large body of research demonstrating the general effect of oxidative stress on signaling pathways, less is …
Paradoxically, accumulating evidence indicates that ROS also serve as critical signaling molecules in cell proliferation and s …
Targeting oxidative stress in disease: promise and limitations of antioxidant therapy.
Forman HJ, Zhang H. Forman HJ, et al. Nat Rev Drug Discov. 2021 Sep;20(9):689-709. doi: 10.1038/s41573-021-00233-1. Epub 2021 Jun 30. Nat Rev Drug Discov. 2021. PMID: 34194012 Free PMC article. Review.
Oxidative stress is a component of many diseases, including atherosclerosis, chronic obstructive pulmonary disease, Alzheimer disease and cancer. Although numerous small molecules evaluated as antioxidants have exhibited therapeutic potential in preclinical studies, clinic …
Oxidative stress is a component of many diseases, including atherosclerosis, chronic obstructive pulmonary disease, Alzheimer disease and ca …
Reactive Oxygen Species in Plant Signaling.
Waszczak C, Carmody M, Kangasjärvi J. Waszczak C, et al. Annu Rev Plant Biol. 2018 Apr 29;69:209-236. doi: 10.1146/annurev-arplant-042817-040322. Epub 2018 Feb 28. Annu Rev Plant Biol. 2018. PMID: 29489394 Review.
Initially considered by-products from aerobic metabolism, reactive oxygen species (ROS) have emerged as major regulatory molecules in plants and their roles in early signaling events initiated by cellular metabolic perturbation and environmental stimuli are now esta …
Initially considered by-products from aerobic metabolism, reactive oxygen species (ROS) have emerged as major regulatory molecules in …
Redox signaling: An evolution from free radicals to aging.
Forman HJ. Forman HJ. Free Radic Biol Med. 2016 Aug;97:398-407. doi: 10.1016/j.freeradbiomed.2016.07.003. Epub 2016 Jul 5. Free Radic Biol Med. 2016. PMID: 27393004 Free PMC article. Review.
Although the concept that signal transduction involved changes in the redox state dates from the 1930s, the modern history of redox biology began with the discovery of superoxide dismutase by McCord and Fridovich. ...Thus, the field of redox
Although the concept that signal transduction involved changes in the redox state dates from the 1930s, the modern hist …
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents.
Sies H, Jones DP. Sies H, et al. Nat Rev Mol Cell Biol. 2020 Jul;21(7):363-383. doi: 10.1038/s41580-020-0230-3. Epub 2020 Mar 30. Nat Rev Mol Cell Biol. 2020. PMID: 32231263 Review.
Here we focus on ROS at physiological levels and their central role in redox signalling via different post-translational modifications, denoted as 'oxidative eustress'. ...In addition, several other reactive species are involved in redox signalling, fo …
Here we focus on ROS at physiological levels and their central role in redox signalling via different post-translational modif …
Free radicals in the physiological control of cell function.
Dröge W. Dröge W. Physiol Rev. 2002 Jan;82(1):47-95. doi: 10.1152/physrev.00018.2001. Physiol Rev. 2002. PMID: 11773609 Free article. Review.
At moderate concentrations, however, nitric oxide (NO), superoxide anion, and related reactive oxygen species (ROS) play an important role as regulatory mediators in signaling processes. Many of the ROS-mediated responses actually protect the cells against oxidative stress …
At moderate concentrations, however, nitric oxide (NO), superoxide anion, and related reactive oxygen species (ROS) play an important role a …
Reactive oxygen species and mitochondria: A nexus of cellular homeostasis.
Dan Dunn J, Alvarez LA, Zhang X, Soldati T. Dan Dunn J, et al. Redox Biol. 2015 Dec;6:472-485. doi: 10.1016/j.redox.2015.09.005. Epub 2015 Sep 10. Redox Biol. 2015. PMID: 26432659 Free PMC article. Review.
Reactive oxygen species (ROS) are integral components of multiple cellular pathways even though excessive or inappropriately localized ROS damage cells. ROS function as anti-microbial effector molecules and as signaling molecules that regulate such processes …
Reactive oxygen species (ROS) are integral components of multiple cellular pathways even though excessive or inappropriately localized ROS d …
5,939 results