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Year Number of Results
1997 1
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2002 8
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2008 16
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2012 32
2013 33
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426 results

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Page 1
Wnt/planar cell polarity signaling controls morphogenetic movements of gastrulation and neural tube closure.
Shi DL. Shi DL. Cell Mol Life Sci. 2022 Nov 12;79(12):586. doi: 10.1007/s00018-022-04620-8. Cell Mol Life Sci. 2022. PMID: 36369349 Free PMC article. Review.
Apical constriction also makes an important contribution to promote the formation of the blastopore and the bending of the neural plate. Planar cell polarity proteins are major regulators of asymmetric cell behaviors and critically involved in a …
Apical constriction also makes an important contribution to promote the formation of the blastopore and the bending of the neural plate. …
Wnt-frizzled planar cell polarity signaling in the regulation of cell motility.
Koca Y, Collu GM, Mlodzik M. Koca Y, et al. Curr Top Dev Biol. 2022;150:255-297. doi: 10.1016/bs.ctdb.2022.03.006. Epub 2022 May 25. Curr Top Dev Biol. 2022. PMID: 35817505 Free PMC article. Review.
The molecular complexes underlying planar cell polarity (PCP) were first identified in Drosophila through analysis of mutant phenotypes in the adult cuticle and the orientation of associated polarized protrusions such as wing hairs and sensory bristles. ...In …
The molecular complexes underlying planar cell polarity (PCP) were first identified in Drosophila through analysis of m …
Wnt signaling in colorectal cancer: pathogenic role and therapeutic target.
Zhao H, Ming T, Tang S, Ren S, Yang H, Liu M, Tao Q, Xu H. Zhao H, et al. Mol Cancer. 2022 Jul 14;21(1):144. doi: 10.1186/s12943-022-01616-7. Mol Cancer. 2022. PMID: 35836256 Free PMC article. Review.
The canonical Wnt signaling pathway regulates cell pluripotency and determines the differentiation fate of cells during development. ...RESULTS: Wnt signaling pathways include: Wnt/beta-catenin or canonical Wnt …
The canonical Wnt signaling pathway regulates cell pluripotency and determines the differentiation fate o …
Wnt signaling in breast cancer: biological mechanisms, challenges and opportunities.
Xu X, Zhang M, Xu F, Jiang S. Xu X, et al. Mol Cancer. 2020 Nov 24;19(1):165. doi: 10.1186/s12943-020-01276-5. Mol Cancer. 2020. PMID: 33234169 Free PMC article. Review.
Wnt signaling is a highly conserved signaling pathway that plays a critical role in controlling embryonic and organ development, as well as cancer progression. ...Wnt/beta-Catenin, Wnt-planar cell polarity (PCP), and …
Wnt signaling is a highly conserved signaling pathway that plays a critical role in controlling embryonic and or …
Role of Wnt signaling and planar cell polarity in left-right asymmetry.
Minegishi K, Sai X, Hamada H. Minegishi K, et al. Curr Top Dev Biol. 2023;153:181-193. doi: 10.1016/bs.ctdb.2023.01.008. Epub 2023 Feb 20. Curr Top Dev Biol. 2023. PMID: 36967194
Wnt signaling plays essential roles in multiple steps of left-right (L-R) determination in development. ...Secondly, planar cell polarity (PCP) driven by non-canonical Wnt signaling polarizes node cells along the anterio-posterior …
Wnt signaling plays essential roles in multiple steps of left-right (L-R) determination in development. ...Secondly, planar …
Activation of Wnt/beta-catenin pathway mitigates blood-brain barrier dysfunction in Alzheimer's disease.
Wang Q, Huang X, Su Y, Yin G, Wang S, Yu B, Li H, Qi J, Chen H, Zeng W, Zhang K, Verkhratsky A, Niu J, Yi C. Wang Q, et al. Brain. 2022 Dec 19;145(12):4474-4488. doi: 10.1093/brain/awac236. Brain. 2022. PMID: 35788280 Free PMC article.
In the cerebral microvessels of APP/PS1 mice and amyloid-beta-treated brain endothelial cells, we found suppressed Wnt/beta-catenin signalling triggered by an increase of GSK3beta activation, but not an inhibition of the AKT pathway or switching to the Wnt/ …
In the cerebral microvessels of APP/PS1 mice and amyloid-beta-treated brain endothelial cells, we found suppressed Wnt/beta-catenin s …
Folate regulation of planar cell polarity pathway and F-actin through folate receptor alpha.
Han X, Cao X, Cabrera RM, Ramirez PAP, Lin YL, Wlodarczyk BJ, Zhang C, Finnell RH, Lei Y. Han X, et al. FASEB J. 2024 Jan;38(1):e23346. doi: 10.1096/fj.202300202R. FASEB J. 2024. PMID: 38095297 Free PMC article.
Mouse embryonic fibroblasts (MEFs) were treated with different folates continuously for three passages, and cell proliferation and F-actin were monitored. We determined that compared to 5mTHF, FA showed stronger effects on promoting cell proliferation and F-actin fo …
Mouse embryonic fibroblasts (MEFs) were treated with different folates continuously for three passages, and cell proliferation and F- …
Wnt signaling.
Eisenmann DM. Eisenmann DM. WormBook. 2005 Jun 25:1-17. doi: 10.1895/wormbook.1.7.1. WormBook. 2005. PMID: 18050402 Free PMC article. Review.
A 'canonical' Wnt signaling pathway has been elucidated in vertebrate and invertebrate model systems. ...However, Wnt binding also acts through beta-catenin-independent, noncanonical pathways, such as the planar cell polarity …
A 'canonical' Wnt signaling pathway has been elucidated in vertebrate and invertebrate model systems. ...However, Wn …
Noncanonical Wnt planar cell polarity signaling in lung development and disease.
Vladar EK, Königshoff M. Vladar EK, et al. Biochem Soc Trans. 2020 Feb 28;48(1):231-243. doi: 10.1042/BST20190597. Biochem Soc Trans. 2020. PMID: 32096543 Free PMC article. Review.
The planar cell polarity (PCP) signaling pathway is a potent developmental regulator of directional cell behaviors such as migration, asymmetric division and morphological polarization that are critical for shaping the body axis an …
The planar cell polarity (PCP) signaling pathway is a potent developmental regulator of directiona …
Wnt regulation of planar cell polarity (PCP).
Gao B. Gao B. Curr Top Dev Biol. 2012;101:263-95. doi: 10.1016/B978-0-12-394592-1.00008-9. Curr Top Dev Biol. 2012. PMID: 23140633 Review.
Planar cell polarity (PCP), a process controlling coordinated, uniformly polarized cellular behaviors in a field of cells, has been identified to be critically required for many fundamental developmental processes. ...In addition, the underlying molecular mec …
Planar cell polarity (PCP), a process controlling coordinated, uniformly polarized cellular behaviors in a field of cel …
426 results