Comparative analysis of armadillo family proteins in the regulation of a431 epithelial cell junction assembly, adhesion and migration.
J Invest Dermatol. 2004.
PMID: 15304078
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Butyrate enhances the intestinal barrier by facilitating tight junction assembly via activation of AMP-activated protein kinase in Caco-2 cell monolayers.
J Nutr. 2009 Sep;139(9):1619-25. doi: 10.3945/jn.109.104638. Epub 2009 Jul 22.
J Nutr. 2009.
PMID: 19625695
Free PMC article.
We further used a calcium switch assay to study the assembly of epithelial tight junctions and determined the effect of butyrate on the assembly of epithelial tight junctions and AMPK activity. ...We conclude that butyrate enhances the intestinal barri …
We further used a calcium switch assay to study the assembly of epithelial tight junctions and determined the effect of butyra …
Regulation of Tjp1 mRNA by CPEB2 for tight junction assembly in mouse blastocyst.
Reproduction. 2022 Feb 24;163(4):233-240. doi: 10.1530/REP-21-0227.
Reproduction. 2022.
PMID: 35133290
Cytoplasmic polyadenylation element-binding protein 2 (CPEB2) is an mRNA-binding protein that regulates the cytoplasmic polyadenylation of mRNA and is required for tight junction (TJ) assembly in the trophectoderm epithelium during porcine preimplantation dev …
Cytoplasmic polyadenylation element-binding protein 2 (CPEB2) is an mRNA-binding protein that regulates the cytoplasmic polyadenylati …
Regulation of connexin biosynthesis, assembly, gap junction formation, and removal.
Biochim Biophys Acta. 2004 Mar 23;1662(1-2):3-21. doi: 10.1016/j.bbamem.2004.01.007.
Biochim Biophys Acta. 2004.
PMID: 15033576
Free article.
Review.
Gap junctions (GJs) are the only known cellular structures that allow a direct transfer of signaling molecules from cell-to-cell by forming hydrophilic channels that bridge the opposing membranes of neighboring cells. The crucial role of GJ-mediated interc …
Gap junctions (GJs) are the only known cellular structures that allow a direct transfer of signaling molecules from cell-to- …
Tight junctions.
Curr Biol. 2023 Nov 6;33(21):R1135-R1140. doi: 10.1016/j.cub.2023.09.027.
Curr Biol. 2023.
PMID: 37935122
Free article.
Individual cells in such barriers are held together by cell-cell adhesion structures - also known as intercellular junctions - that are essential for barrier formation and maintenance. ...We will also discuss additional functions of TJs in cell …
Individual cells in such barriers are held together by cell-cell adhesion structures - also known as intercellular j …
Regulation of Cell Polarity by Exocyst-Mediated Trafficking.
Cold Spring Harb Perspect Biol. 2018 Mar 1;10(3):a031401. doi: 10.1101/cshperspect.a031401.
Cold Spring Harb Perspect Biol. 2018.
PMID: 28264817
Free PMC article.
Review.
Asymmetric membrane trafficking is also a critical mechanism to regulate cell differentiation, signaling, and physiology. Many eukaryotic cell types use the eight-protein exocyst complex to orchestrate polarized vesicle trafficking to certain membrane locales …
Asymmetric membrane trafficking is also a critical mechanism to regulate cell differentiation, signaling, and physiology. Many …
Regulation of Cx43 Gap Junction Intercellular Communication by Bruton's Tyrosine Kinase and Interleukin-2-Inducible T-Cell Kinase.
Biomolecules. 2023 Apr 8;13(4):660. doi: 10.3390/biom13040660.
Biomolecules. 2023.
PMID: 37189407
Free PMC article.
Overexpression of BTK or ITK in the HEK-293T cells led to increased Cx43 tyrosine phosphorylation as well as decreased gap junction intercellular communication (GJIC) and Cx43 membrane localization. In the lymphocytes, activation of the B cell receptor (Daudi …
Overexpression of BTK or ITK in the HEK-293T cells led to increased Cx43 tyrosine phosphorylation as well as decreased gap junction …
Regulation of desmosome assembly and adhesion.
Semin Cell Dev Biol. 2004 Dec;15(6):665-77. doi: 10.1016/j.semcdb.2004.09.005.
Semin Cell Dev Biol. 2004.
PMID: 15561586
Review.
Desmosomes are highly organized intercellular junctions that provide mechanical integrity to tissues by anchoring intermediate filaments to sites of strong adhesion. ...Desmosome assembly and disassembly are regulated post-translationally by calcium, k …
Desmosomes are highly organized intercellular junctions that provide mechanical integrity to tissues by anchoring intermediate …
Regulation of gap junction channels and hemichannels by phosphorylation and redox changes: a revision.
BMC Cell Biol. 2016 May 24;17 Suppl 1(Suppl 1):11. doi: 10.1186/s12860-016-0099-3.
BMC Cell Biol. 2016.
PMID: 27229925
Free PMC article.
Review.
Post-translational modifications of connexins play an important role in the regulation of gap junction and hemichannel permeability. The prerequisite for the formation of functional gap junction channels is the assembly of connexin proteins into hemich …
Post-translational modifications of connexins play an important role in the regulation of gap junction and hemichannel permeab …
Non-Cell-Autonomous Function of the GPI-Anchored Protein Undicht during Septate Junction Assembly.
Cell Rep. 2019 Feb 5;26(6):1641-1653.e4. doi: 10.1016/j.celrep.2019.01.046.
Cell Rep. 2019.
PMID: 30726744
Free article.
Occluding cell-cell junctions are pivotal during the development of many organs. One example is septate junction (SJ) strands, which are found in vertebrates and invertebrates. ...Here, we identified a GPI-anchored protein called Undicht required for s …
Occluding cell-cell junctions are pivotal during the development of many organs. One example is septate junction …
Regulation of small GTPases at epithelial cell-cell junctions.
Mol Membr Biol. 2011 Oct-Nov;28(7-8):427-44. doi: 10.3109/09687688.2011.603101. Epub 2011 Jul 25.
Mol Membr Biol. 2011.
PMID: 21781017
Free article.
Review.
Small GTPases of the Rho family (RhoA, Rac1, and Cdc42) and the Ras family GTPase Rap1 are essential for the assembly and function of epithelial cell-cell junctions. Through their downstream effectors, small GTPases modulate junction formation a …
Small GTPases of the Rho family (RhoA, Rac1, and Cdc42) and the Ras family GTPase Rap1 are essential for the assembly and function of …
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